-
1
-
-
0031734471
-
Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide
-
Alexeev V, Yoon K. Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide. Nat Biotechnol 1998; 16: 1343-1346.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 1343-1346
-
-
Alexeev, V.1
Yoon, K.2
-
2
-
-
0030772320
-
Targeted gene conversion in a mammalian CD34+-enriched cell population using a chimeric RNA/DNA oligonucleotide
-
Xiang Y et al. Targeted gene conversion in a mammalian CD34+-enriched cell population using a chimeric RNA/DNA oligonucleotide. J Mol Med 1997; 75: 829-835.
-
(1997)
J. Mol. Med.
, vol.75
, pp. 829-835
-
-
Xiang, Y.1
-
3
-
-
0033392739
-
A sequence-specific gene correction by an RNA-DNA oligonucleotide in mammalian cells characterized by transfection and nuclear extract using a lacZ shuttle system
-
Igoucheva O, Peritz AE, Levy D, Yoon K. A sequence-specific gene correction by an RNA-DNA oligonucleotide in mammalian cells characterized by transfection and nuclear extract using a lacZ shuttle system. Gene Therapy 1999; 6: 1960-1971.
-
(1999)
Gene Therapy
, vol.6
, pp. 1960-1971
-
-
Igoucheva, O.1
Peritz, A.E.2
Levy, D.3
Yoon, K.4
-
4
-
-
0035077792
-
Targeted gene correction by small single-stranded oligonucleotides in mammalian cells
-
Igoucheva O, Alexeev V, Yoon K. Targeted gene correction by small single-stranded oligonucleotides in mammalian cells. Gene Therapy 2001; 8: 391-399.
-
(2001)
Gene Therapy
, vol.8
, pp. 391-399
-
-
Igoucheva, O.1
Alexeev, V.2
Yoon, K.3
-
5
-
-
0042878534
-
A comparison of gene repair strategies in cell culture using a lacZ reporter system
-
Nickerson HD, Colledge WH. A comparison of gene repair strategies in cell culture using a lacZ reporter system. Gene Therapy 2003; 10: 1584-1591.
-
(2003)
Gene Therapy
, vol.10
, pp. 1584-1591
-
-
Nickerson, H.D.1
Colledge, W.H.2
-
6
-
-
0141927821
-
Correction/mutation of acid alpha-D-glucosidase gene by modified single-stranded oligonucleotides: In vitro and in vivo studies
-
Lu IL et al. Correction/mutation of acid alpha-D-glucosidase gene by modified single-stranded oligonucleotides: in vitro and in vivo studies. Gene Therapy 2003; 10: 1910-1916.
-
(2003)
Gene Therapy
, vol.10
, pp. 1910-1916
-
-
Lu, I.L.1
-
7
-
-
0031953132
-
In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides
-
(see comments)
-
Kren BT, Bandyopadhyay P, Steer CJ. In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides (see comments). Nat Med 1998; 4: 285-290.
-
(1998)
Nat. Med.
, vol.4
, pp. 285-290
-
-
Kren, B.T.1
Bandyopadhyay, P.2
Steer, C.J.3
-
8
-
-
0033621041
-
Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide
-
Kren BT et al. Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide. Proc Natl Acad Sci USA 1999; 96: 10349-10354.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10349-10354
-
-
Kren, B.T.1
-
9
-
-
0033989521
-
Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide
-
(see comments)
-
Alexeev V et al. Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide (see comments). Nat Biotechnol 2000; 18: 43-47.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 43-47
-
-
Alexeev, V.1
-
10
-
-
0034086776
-
In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA:DNA oligonucleotide
-
Bartlett RJ et al. In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA:DNA oligonucleotide. Nat Biotechnol 2000; 18: 615-622.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 615-622
-
-
Bartlett, R.J.1
-
11
-
-
0034743499
-
Expression of DeltaF508 CFTR in normal mouse lung after site-specific modification of CFTR sequences by SFHR
-
Goncz KK et al. Expression of DeltaF508 CFTR in normal mouse lung after site-specific modification of CFTR sequences by SFHR. Gene Therapy 2001; 8: 961-965.
-
(2001)
Gene Therapy
, vol.8
, pp. 961-965
-
-
Goncz, K.K.1
-
12
-
-
0035831649
-
In vivo and in vitro correction of the mdx dystrophin gene nonsense mutation by short-fragment homologous replacement
-
Kapsa R et al. In vivo and in vitro correction of the mdx dystrophin gene nonsense mutation by short-fragment homologous replacement. Hum Gene Ther 2001; 12: 629-642.
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 629-642
-
-
Kapsa, R.1
-
13
-
-
0035918314
-
Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty
-
Tagalakis AD et al. Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty. J Biol Chem 2001; 276: 13226-13230.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 13226-13230
-
-
Tagalakis, A.D.1
-
14
-
-
0030990991
-
Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells
-
Zambrowicz BP et al. Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci USA 1997; 94: 3789-3794.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3789-3794
-
-
Zambrowicz, B.P.1
-
15
-
-
0025992469
-
Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice
-
Friedrich G, Soriano P. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 1991; 5: 1513-1523.
-
(1991)
Genes Dev.
, vol.5
, pp. 1513-1523
-
-
Friedrich, G.1
Soriano, P.2
-
16
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
(letter)
-
Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain (letter). Nat Genet 1999; 21: 70-71.
-
(1999)
Nat. Genet.
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
17
-
-
0033608980
-
Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice
-
Mao X, Fujiwara Y, Orkin SH. Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice. Proc Natl Acad Sci USA 1999; 96: 5037-5042.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5037-5042
-
-
Mao, X.1
Fujiwara, Y.2
Orkin, S.H.3
-
18
-
-
0035185002
-
An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus
-
Awatramani R, Soriano P, Mai JJ, Dymecki S. An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus. Nat Genet 2001; 29: 257-259.
-
(2001)
Nat. Genet.
, vol.29
, pp. 257-259
-
-
Awatramani, R.1
Soriano, P.2
Mai, J.J.3
Dymecki, S.4
-
19
-
-
0025339237
-
A set of lacZ mutations in Escherichia coli that allow rapid detection of specific frameshift mutations
-
Cupples CG, Cabrera M, Cruz C, Miller JH. A set of lacZ mutations in Escherichia coli that allow rapid detection of specific frameshift mutations. Genetics 1990; 125: 275-280.
-
(1990)
Genetics
, vol.125
, pp. 275-280
-
-
Cupples, C.G.1
Cabrera, M.2
Cruz, C.3
Miller, J.H.4
-
20
-
-
0034329384
-
Targeted single-base correction by RNA-DNA oligonucleotides
-
Igoucheva O, Yoon K. Targeted single-base correction by RNA-DNA oligonucleotides. Hum Gene Ther 2000; 11: 2307-2312.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 2307-2312
-
-
Igoucheva, O.1
Yoon, K.2
-
21
-
-
0037265663
-
Oligonucleotide-directed single-base DNA alterations in mouse embryonic stem cells
-
Pierce EA et al. Oligonucleotide-directed single-base DNA alterations in mouse embryonic stem cells. Gene Therapy 2003; 10: 24-33.
-
(2003)
Gene Therapy
, vol.10
, pp. 24-33
-
-
Pierce, E.A.1
-
22
-
-
0037133550
-
Embryonic stem cells and somatic cells differ in mutation frequency and type
-
Cervantes RB et al. Embryonic stem cells and somatic cells differ in mutation frequency and type. Proc Natl Acad Sci USA 2002; 99: 3586-3590.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 3586-3590
-
-
Cervantes, R.B.1
-
23
-
-
0029020950
-
Plasmid DNA entry into postmitotic nuclei of primary rat myotubes
-
Dowty ME et al. Plasmid DNA entry into postmitotic nuclei of primary rat myotubes. Proc Natl Acad Sci USA 1995; 92: 4572-4576.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4572-4576
-
-
Dowty, M.E.1
-
24
-
-
0030768810
-
Nuclear import of DNA in digitonin-permeabilized cells
-
Hagstrom JE et al. Nuclear import of DNA in digitonin-permeabilized cells. J Cell Sci 1997; 110 (Part 18): 2323-2331.
-
(1997)
J. Cell Sci.
, vol.110
, Issue.PART 18
, pp. 2323-2331
-
-
Hagstrom, J.E.1
-
25
-
-
0025838289
-
Analysis of spontaneous and induced mutations in transgenic mice using a lambda ZAP/lacI shuttle vector
-
Kohler SW et al. Analysis of spontaneous and induced mutations in transgenic mice using a lambda ZAP/lacI shuttle vector. Environ Mol Mutagen 1991; 18: 316-321.
-
(1991)
Environ. Mol. Mutagen.
, vol.18
, pp. 316-321
-
-
Kohler, S.W.1
-
26
-
-
0024374202
-
Efficient rescue of integrated shuttle vectors from transgenic mice: A model for studying mutations in vivo
-
Gossen JA et al. Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo. Proc Natl Acad Sci USA 1989; 86: 7971-7975.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7971-7975
-
-
Gossen, J.A.1
-
27
-
-
0032511836
-
A comparative study of in vivo mutation assays: Analysis of hprt, lacI, cII/cI and as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue mice
-
Monroe JJ et al. A comparative study of in vivo mutation assays: analysis of hprt, lacI, cII/cI and as mutational targets for N-nitroso-N-methylurea and benzo[a]pyrene in Big Blue mice. Mutat Res 1998; 421: 121-136.
-
(1998)
Mutat. Res.
, vol.421
, pp. 121-136
-
-
Monroe, J.J.1
-
28
-
-
0031688612
-
Inflammatory responses following direct injection of plasmid DNA into skeletal muscle
-
McMahon JM et al. Inflammatory responses following direct injection of plasmid DNA into skeletal muscle. Gene Therapy 1998; 5: 1283-1290.
-
(1998)
Gene Therapy
, vol.5
, pp. 1283-1290
-
-
McMahon, J.M.1
-
30
-
-
0036953421
-
Simultaneous targeted alteration of the tyrosinase and c-kit genes by single-stranded oligonucleotides
-
Alexeev V, Igoucheva O, Yoon K. Simultaneous targeted alteration of the tyrosinase and c-kit genes by single-stranded oligonucleotides. Gene Therapy 2002; 9: 1667-1675.
-
(2002)
Gene Therapy
, vol.9
, pp. 1667-1675
-
-
Alexeev, V.1
Igoucheva, O.2
Yoon, K.3
-
31
-
-
0037053330
-
Tyrosine kinase c-Src constitutes a bridge between cystic fibrosis transmembrane regulator channel failure and MUC1 overexpression in cystic fibrosis
-
Gonzaez-Guerrico AM et al. Tyrosine kinase c-Src constitutes a bridge between cystic fibrosis transmembrane regulator channel failure and MUC1 overexpression in cystic fibrosis. J Biol Chem 2002; 277: 17239-17247.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 17239-17247
-
-
Gonzaez-Guerrico, A.M.1
-
32
-
-
0036268053
-
Application of SFHR to gene therapy of monogenic disorders
-
Goncz KK et al. Application of SFHR to gene therapy of monogenic disorders. Gene Therapy 2002; 9: 691-694.
-
(2002)
Gene Therapy
, vol.9
, pp. 691-694
-
-
Goncz, K.K.1
-
33
-
-
0035287212
-
Enhanced gene delivery to human airway epithelial cells using an integrin-targeting lipoplex
-
Scott ES, Wiseman JW, Evans MJ, Colledge WH. Enhanced gene delivery to human airway epithelial cells using an integrin-targeting lipoplex. J Gene Med 2001; 3: 125-134.
-
(2001)
J. Gene Med.
, vol.3
, pp. 125-134
-
-
Scott, E.S.1
Wiseman, J.W.2
Evans, M.J.3
Colledge, W.H.4
-
34
-
-
0034743705
-
Targeted correction of a defective selectable marker gene in human epithelial cells by small DNA fragments
-
Colosimo A et al. Targeted correction of a defective selectable marker gene in human epithelial cells by small DNA fragments. Mol Ther 2001; 3: 178-185.
-
(2001)
Mol. Ther.
, vol.3
, pp. 178-185
-
-
Colosimo, A.1
-
35
-
-
0035171056
-
Steroid hormone enhancement of gene delivery to a human airway epithelial cell line in vitro and mouse airways in vivo
-
Wiseman JW, Goddard CA, Colledge WH. Steroid hormone enhancement of gene delivery to a human airway epithelial cell line in vitro and mouse airways in vivo. Gene Therapy 2001; 8: 1562-1571.
-
(2001)
Gene Therapy
, vol.8
, pp. 1562-1571
-
-
Wiseman, J.W.1
Goddard, C.A.2
Colledge, W.H.3
-
36
-
-
0036401268
-
A nonionic amphiphile agent promotes gene delivery in vivo to skeletal and cardiac muscles
-
Pitard B et al. A nonionic amphiphile agent promotes gene delivery in vivo to skeletal and cardiac muscles. Hum Gene Ther 2002; 13: 1767-1775.
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 1767-1775
-
-
Pitard, B.1
|