Biochemical and biological responses induced by coupling of Gab1 to phosphatidylinositol 3-kinase in RET-expressing cells

Biochemical and Biophysical Research Communications

Volumn 323, Issue 1, 2004, Pages 345-354

  Maeda, Kengo ^a   Murakami, Hideki ^a   Yoshida, Reiko ^a   Ichihara, Masatoshi ^a   Abe, Akihiro ^a   Hirai, Makoto ^b   Murohara, Toyoaki ^a   Takahashi, Masahide ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

Apoptosis; Gab1; GDNF; Lamellipodia; RET tyrosine kinase

Indexed keywords

BINDING PROTEIN; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN GAB1; PROTEIN RET; PROTEIN TYROSINE PHOSPHATASE SHP 2; RAC1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CARCINOMA CELL; CELL SURVIVAL; CONTROLLED STUDY; ENDOCRINE TUMOR; ENZYME ACTIVATION; ENZYME BINDING; ENZYME RELEASE; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOUSE; NEUROECTODERM TUMOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; THYROID MEDULLARY CARCINOMA; TUMOR CELL; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; BINDING SITES; CELL LINE, TUMOR; CELL SEPARATION; CYTOCHROMES C; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ETOPOSIDE; FLOW CYTOMETRY; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; GLUTATHIONE TRANSFERASE; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICE; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; NERVE GROWTH FACTORS; NIH 3T3 CELLS; PHOSPHOPROTEINS; PLASMIDS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RET; RECEPTOR PROTEIN-TYROSINE KINASES; RETROVIRIDAE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 4444293961     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.08.095     Document Type: Article

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