Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival

Cancer Research

Volumn 60, Issue 14, 2000, Pages 3727-3731

  De Vita, Gabriella ^a   Melillo, Rosa Marina ^a   Carlomagno, Francesca ^a   Visconti, Roberta ^a   Castellone, Maria Domenica ^a   Bellacosa, Alfonso ^b,c   Billaud, Marc ^d   Fusco, Alfredo ^e   Tsichlis, Philip N ^f   Santoro, Massimo ^a  

^a CNR   (Italy)

^b FOX CHASE CANCER CENTER   (United States)

^c CATHOLIC UNIVERSITY   (Italy)

^d CNRS   (France)

^e Dipartimento di Medicina Sperimentale e Clinica   (Italy)

^f THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P85; TYROSINE;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; ENZYME ACTIVATION; GERM LINE; HIRSCHSPRUNG DISEASE; NONHUMAN; PHEOCHROMOCYTOMA CELL; POINT MUTATION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SIPPLE SYNDROME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOTTING, WESTERN; CELL SURVIVAL; CHROMONES; CULTURE MEDIA, SERUM-FREE; DNA FRAGMENTATION; DROSOPHILA PROTEINS; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; IN SITU NICK-END LABELING; LIGANDS; MAP KINASE SIGNALING SYSTEM; MORPHOLINES; MULTIPLE ENDOCRINE NEOPLASIA TYPE 2A; PC12 CELLS; PRECIPITIN TESTS; PROTEIN ISOFORMS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-RET; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; TRANSFECTION; TYROSINE;

EID: 0034660859     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

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