메뉴 건너뛰기




Volumn 155, Issue 1-2, 2004, Pages 43-54

Interleukin-6 produces neuronal loss in developing cerebellar granule neuron cultures

Author keywords

CNS inflammation; Cytokine; Neurodevelopment; Neuroimmune interactions; Neurotoxicity; NMDA

Indexed keywords

INTERLEUKIN 6; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 4444249316     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2004.06.014     Document Type: Article
Times cited : (95)

References (61)
  • 1
    • 0035943096 scopus 로고    scopus 로고
    • Predictive value of serum interleukin-6 level in influenza virus-associated encephalopathy
    • H. Aiba, M. Mochizuki, M. Kimura, and H. Hojo Predictive value of serum interleukin-6 level in influenza virus-associated encephalopathy Neurology 57 2001 199 295
    • (2001) Neurology , vol.57 , pp. 199-295
    • Aiba, H.1    Mochizuki, M.2    Kimura, M.3    Hojo, H.4
  • 2
  • 3
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • M. Ankarcrona, J.M. Dypbukt, E. Bonfoco, G. Zhivotovsky, S. Orrenius, S. Lipton, and P. Nicotera Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function Neuron 15 1995 961 973
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, G.4    Orrenius, S.5    Lipton, S.6    Nicotera, P.7
  • 4
    • 0023939128 scopus 로고
    • Effect of depolarization on the maturation of cerebellar granule cells in culture
    • R. Balazs, V. Gallo, and A. Kingsbury Effect of depolarization on the maturation of cerebellar granule cells in culture Brain Res. 468 1988 269 276
    • (1988) Brain Res. , vol.468 , pp. 269-276
    • Balazs, R.1    Gallo, V.2    Kingsbury, A.3
  • 5
    • 0023901981 scopus 로고
    • Stimulation of the N-methyl-d-aspartate receptor has a trophic effect on differentiating cerebellar granule cells
    • R. Balazs, N. Hack, and O.S. Jorgensen Stimulation of the N-methyl-d-aspartate receptor has a trophic effect on differentiating cerebellar granule cells Neurosci. Lett. 87 1988 80 86
    • (1988) Neurosci. Lett. , vol.87 , pp. 80-86
    • Balazs, R.1    Hack, N.2    Jorgensen, O.S.3
  • 6
    • 0023804295 scopus 로고
    • N-Methyl-d-aspartate promotes the survival of cerebellar granule cells in culture
    • R. Balazs, O.S. Jorgensen, and N. Hack N-Methyl-d-aspartate promotes the survival of cerebellar granule cells in culture Neuroscience 27 1988 437 451
    • (1988) Neuroscience , vol.27 , pp. 437-451
    • Balazs, R.1    Jorgensen, O.S.2    Hack, N.3
  • 7
    • 0024375059 scopus 로고
    • N-Methyl-d-aspartate promotes the survival of cerebellar granule cells: Pharmacological characterization
    • R. Balazs, N. Hack, O.S. Jorgensen, and C.W. Cotman N-Methyl-d-aspartate promotes the survival of cerebellar granule cells: pharmacological characterization Neurosci. Lett. 101 1989 241 246
    • (1989) Neurosci. Lett. , vol.101 , pp. 241-246
    • Balazs, R.1    Hack, N.2    Jorgensen, O.S.3    Cotman, C.W.4
  • 10
    • 0028843876 scopus 로고
    • Reduced long-term potentiation in the dentate gyrus of transgenic mice with cerebral overexpression of interleukin-6
    • F.P. Bellinger, S.G. Madamba, I.L. Campbell, and G.R. Siggins Reduced long-term potentiation in the dentate gyrus of transgenic mice with cerebral overexpression of interleukin-6 Neurosci. Lett. 198 1995 95 98
    • (1995) Neurosci. Lett. , vol.198 , pp. 95-98
    • Bellinger, F.P.1    Madamba, S.G.2    Campbell, I.L.3    Siggins, G.R.4
  • 11
    • 0001596469 scopus 로고    scopus 로고
    • Techniques for distinguishing apoptosis from necrosis in cerebrocortical and cerebellar neurons
    • E. Bonfoco, M. Ankarcrona, D. Krainc, P. Nicotera, and S. Lipton Techniques for distinguishing apoptosis from necrosis in cerebrocortical and cerebellar neurons Neuromethods 29 1997 237 253
    • (1997) Neuromethods , vol.29 , pp. 237-253
    • Bonfoco, E.1    Ankarcrona, M.2    Krainc, D.3    Nicotera, P.4    Lipton, S.5
  • 12
    • 0033032141 scopus 로고    scopus 로고
    • Neurons depend on astrocytes in a coculture system for protection from glutamate toxicity
    • D.R. Brown Neurons depend on astrocytes in a coculture system for protection from glutamate toxicity Mol. Cell. Neurosci. 13 1999 379 389
    • (1999) Mol. Cell. Neurosci. , vol.13 , pp. 379-389
    • Brown, D.R.1
  • 13
    • 0029044650 scopus 로고    scopus 로고
    • Neuropathogenic actions of cytokines assessed in transgenic mice
    • I.L. Campbell Neuropathogenic actions of cytokines assessed in transgenic mice Int. J. Dev. Neurosci. 13 1996 275 284
    • (1996) Int. J. Dev. Neurosci. , vol.13 , pp. 275-284
    • Campbell, I.L.1
  • 14
    • 0032077767 scopus 로고    scopus 로고
    • Transgenic mice and cytokine actions in the brain: Bridging the gap between structural and functional neuropathology
    • I.L. Campbell Transgenic mice and cytokine actions in the brain: bridging the gap between structural and functional neuropathology Brain Res. Rev. 26 1998 327 336
    • (1998) Brain Res. Rev. , vol.26 , pp. 327-336
    • Campbell, I.L.1
  • 16
    • 0033215124 scopus 로고    scopus 로고
    • Inflammatory cytokines IL-1α, IL-1β, IL-6 and TNFα impart neuroprotection to an excitotoxin through distinct pathways
    • N.G. Carlson, W.A. Wieggel, J. Chen, A. Bacchi, S. Rogers, and L.C. Gahring Inflammatory cytokines IL-1α, IL-1β, IL-6 and TNFα impart neuroprotection to an excitotoxin through distinct pathways J. Immunol. 163 1999 3963 3968
    • (1999) J. Immunol. , vol.163 , pp. 3963-3968
    • Carlson, N.G.1    Wieggel, W.A.2    Chen, J.3    Bacchi, A.4    Rogers, S.5    Gahring, L.C.6
  • 17
    • 0027098010 scopus 로고
    • N-Methyl-d-aspartate exposure blocks glutamate toxicity in cultured cerebellar granule cells
    • D.-M. Chanug, X.-M. Gao, and S.M. Paul N-Methyl-d-aspartate exposure blocks glutamate toxicity in cultured cerebellar granule cells Mol. Pharmacol. 42 1992 210 216
    • (1992) Mol. Pharmacol. , vol.42 , pp. 210-216
    • Chanug, D.-M.1    Gao, X.-M.2    Paul, S.M.3
  • 18
    • 0028598750 scopus 로고
    • Reactive gliosis as a consequence of interleukin-6 expression in the brain: Studies in transgenic mice
    • C.-S. Chiang, A. Stalder, A. Samimi, and I.L. Campbell Reactive gliosis as a consequence of interleukin-6 expression in the brain: studies in transgenic mice Dev. Neurosci. 16 1994 212 221
    • (1994) Dev. Neurosci. , vol.16 , pp. 212-221
    • Chiang, C.-S.1    Stalder, A.2    Samimi, A.3    Campbell, I.L.4
  • 19
    • 0029670953 scopus 로고    scopus 로고
    • α-Internexin is the only neuronal intermediate filament expressed in developing cerebellar granule neurons
    • C.L. Chien, C.A. Mason, and R.K. Liem α-Internexin is the only neuronal intermediate filament expressed in developing cerebellar granule neurons J. Neurobiol. 29 1996 304 318
    • (1996) J. Neurobiol. , vol.29 , pp. 304-318
    • Chien, C.L.1    Mason, C.A.2    Liem, R.K.3
  • 20
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • D.W. Choi Excitotoxic cell death J. Neurobiol. 23 1992 1261 1276
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 21
    • 0030924241 scopus 로고    scopus 로고
    • Maternal intrauterine infection, cytokines, and brain damage in the preterm newborn
    • O. Dammann, and A. Leviton Maternal intrauterine infection, cytokines, and brain damage in the preterm newborn Pediatr. Res. 42 1997 1 8
    • (1997) Pediatr. Res. , vol.42 , pp. 1-8
    • Dammann, O.1    Leviton, A.2
  • 22
    • 0036317426 scopus 로고    scopus 로고
    • Neonatal encephalopathy in the term infant: Neuroimaging and inflammatory cytokines
    • A. Foster-Barber, and D.M. Ferriero Neonatal encephalopathy in the term infant: neuroimaging and inflammatory cytokines Ment. Retard. Dev. Disabil. Res. Rev. 8 2002 20 24
    • (2002) Ment. Retard. Dev. Disabil. Res. Rev. , vol.8 , pp. 20-24
    • Foster-Barber, A.1    Ferriero, D.M.2
  • 23
    • 0028069262 scopus 로고
    • Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development
    • R.A. Gadient, and U. Otten Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development Brain Res. 637 1994 10 14
    • (1994) Brain Res. , vol.637 , pp. 10-14
    • Gadient, R.A.1    Otten, U.2
  • 24
    • 0027949041 scopus 로고
    • Identification of interleukin-6 (IL-6)-expressing neurons in the cerebellum and hippocampus of normal adult rats
    • R.A. Gadient, and U. Otten Identification of interleukin-6 (IL-6)-expressing neurons in the cerebellum and hippocampus of normal adult rats Neurosci. Lett. 182 1994 243 246
    • (1994) Neurosci. Lett. , vol.182 , pp. 243-246
    • Gadient, R.A.1    Otten, U.2
  • 25
    • 0023337641 scopus 로고
    • Morphological and physiological differentiation of Purkinje neurons in cultures of rat cerebellum
    • D.L. Gruol, and C.L. Franklin Morphological and physiological differentiation of Purkinje neurons in cultures of rat cerebellum J. Neurosci. 7 1987 1271 1293
    • (1987) J. Neurosci. , vol.7 , pp. 1271-1293
    • Gruol, D.L.1    Franklin, C.L.2
  • 26
    • 0031301027 scopus 로고    scopus 로고
    • Physiological and pathological roles of interleukin-6 in the central nervous system
    • D.L. Gruol, and T.E. Nelson Physiological and pathological roles of interleukin-6 in the central nervous system Mol. Neurobiol. 15 1997 307 339
    • (1997) Mol. Neurobiol. , vol.15 , pp. 307-339
    • Gruol, D.L.1    Nelson, T.E.2
  • 27
    • 0036663074 scopus 로고    scopus 로고
    • The role of gp130 in cerebral cortical development: In vitro functional analysis in a mouse exo utero system
    • T. Hatta, K. Moriyama, K. Nakashima, T. Taga, and H. Otani The role of gp130 in cerebral cortical development: in vitro functional analysis in a mouse exo utero system J. Neurosci. 22 2002 5516 5524
    • (2002) J. Neurosci. , vol.22 , pp. 5516-5524
    • Hatta, T.1    Moriyama, K.2    Nakashima, K.3    Taga, T.4    Otani, H.5
  • 28
    • 0031028141 scopus 로고    scopus 로고
    • Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin-6 in the brain
    • C.J. Heyser, E. Masliah, A. Samimi, I.L. Campbell, and L.H. Gold Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin-6 in the brain Proc. Natl. Acad. Sci. U. S. A. 94 1997 1500 1505
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 1500-1505
    • Heyser, C.J.1    Masliah, E.2    Samimi, A.3    Campbell, I.L.4    Gold, L.H.5
  • 29
    • 0031934336 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 in cerebrospinal fluid from children with prolonged febrile seizure. Comparison with acute encephalitis/encephalopathy
    • T. Ichiyama, M. Nishikawa, T. Yoshitomi, T. Hayashi, and S. Furukawa Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 in cerebrospinal fluid from children with prolonged febrile seizure. Comparison with acute encephalitis/encephalopathy Neurology 50 1998 407 411
    • (1998) Neurology , vol.50 , pp. 407-411
    • Ichiyama, T.1    Nishikawa, M.2    Yoshitomi, T.3    Hayashi, T.4    Furukawa, S.5
  • 30
    • 0003917826 scopus 로고
    • Methods for studying cell death and viability in primary neuronal cultures
    • L.M. Schwartz B.A. Osborn Academic Press San Diego
    • J.E. Johnson Methods for studying cell death and viability in primary neuronal cultures L.M. Schwartz B.A. Osborn Cell Death 1995 Academic Press San Diego 242 276
    • (1995) Cell Death , pp. 242-276
    • Johnson, J.E.1
  • 31
    • 0026658025 scopus 로고
    • Interleukin-6 and leukemia inhibitory factor promote the survival of acetylcholinesterase-positive neurons in culture from embryonic rat spinal
    • Y. Kushima, and H. Hatanaka Interleukin-6 and leukemia inhibitory factor promote the survival of acetylcholinesterase-positive neurons in culture from embryonic rat spinal Neurosci. Lett. 143 1992 110 114
    • (1992) Neurosci. Lett. , vol.143 , pp. 110-114
    • Kushima, Y.1    Hatanaka, H.2
  • 32
    • 0026579153 scopus 로고
    • Interleukin-6 as a neurotrophic factor for promoting the survival of cultured catecholaminergic neurons in a chemically defined medium from fetal and postnatal rat midbrains
    • Y. Kushima, T. Hama, and H. Hatanaka Interleukin-6 as a neurotrophic factor for promoting the survival of cultured catecholaminergic neurons in a chemically defined medium from fetal and postnatal rat midbrains Neurosci. Res. 13 1992 267 280
    • (1992) Neurosci. Res. , vol.13 , pp. 267-280
    • Kushima, Y.1    Hama, T.2    Hatanaka, H.3
  • 33
    • 0024392837 scopus 로고
    • Neurotransmitter regulation of neuronal outgrowth, plasticity and survival
    • S.A. Lipton, and S.B. Kater Neurotransmitter regulation of neuronal outgrowth, plasticity and survival TINS 12 1989 265 270
    • (1989) TINS , vol.12 , pp. 265-270
    • Lipton, S.A.1    Kater, S.B.2
  • 34
    • 0031894808 scopus 로고    scopus 로고
    • Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat
    • S.A. Loddick, A.V. Turnbull, and N.J. Rothwell Cerebral interleukin-6 is neuroprotective during permanent focal cerebral ischemia in the rat J. Cereb. Blood Flow Metab. 18 1998 176 179
    • (1998) J. Cereb. Blood Flow Metab. , vol.18 , pp. 176-179
    • Loddick, S.A.1    Turnbull, A.V.2    Rothwell, N.J.3
  • 35
    • 0026747874 scopus 로고
    • N-Methyl-d-aspartate receptor-mediated neuroprotection in cerebellar granule cells requires new RNA and protein synthesis
    • A.M. Marini, and S.M. Paul N-Methyl-d-aspartate receptor-mediated neuroprotection in cerebellar granule cells requires new RNA and protein synthesis Proc. Natl. Acad. Sci. U. S. A. 89 1992 6555 6559
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 6555-6559
    • Marini, A.M.1    Paul, S.M.2
  • 36
    • 0037396768 scopus 로고    scopus 로고
    • Radiation injury and neurogenesis
    • M.L. Monje, and T. Palmer Radiation injury and neurogenesis Curr. Opin. Neurol. 16 2003 129 134
    • (2003) Curr. Opin. Neurol. , vol.16 , pp. 129-134
    • Monje, M.L.1    Palmer, T.2
  • 37
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory blockade restores adult hippocampal neurogenesis
    • M.L. Monje, H. Toda, and T.D. Palmer Inflammatory blockade restores adult hippocampal neurogenesis Science 30 2003 1760 1765
    • (2003) Science , vol.30 , pp. 1760-1765
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 38
    • 0033802839 scopus 로고    scopus 로고
    • Blockade of the NMDA receptor increases developmental apoptotic elimination of granule neurons and activates caspases in the rat cerebellum
    • B. Monti, and A. Contestabile Blockade of the NMDA receptor increases developmental apoptotic elimination of granule neurons and activates caspases in the rat cerebellum Eur. J. Neurosci. 2000 3117 3123
    • (2000) Eur. J. Neurosci. , pp. 3117-3123
    • Monti, B.1    Contestabile, A.2
  • 39
    • 0036314843 scopus 로고    scopus 로고
    • Chronic interleukin-6 treatment alters electrophysiological properties and calcium signaling in cerebellar Purkinje neurons in culture
    • T.E. Nelson, and D.L. Gruol Chronic interleukin-6 treatment alters electrophysiological properties and calcium signaling in cerebellar Purkinje neurons in culture J. Neurophysiol. 88 2002 475 486
    • (2002) J. Neurophysiol. , vol.88 , pp. 475-486
    • Nelson, T.E.1    Gruol, D.L.2
  • 40
    • 0033105025 scopus 로고    scopus 로고
    • Altered physiology of Purkinje neurons in cerebellar slices from transgenic mice with chronic central nervous system expression of interleukin-6
    • T.E. Nelson, I.L. Campbell, and D.L. Gruol Altered physiology of Purkinje neurons in cerebellar slices from transgenic mice with chronic central nervous system expression of interleukin-6 Neuroscience 89 1999 127 136
    • (1999) Neuroscience , vol.89 , pp. 127-136
    • Nelson, T.E.1    Campbell, I.L.2    Gruol, D.L.3
  • 41
    • 0037532683 scopus 로고    scopus 로고
    • Interleukin-6, beta-amyloid peptide and NMDA interactions in rat cortical neurons
    • Z. Qiu, and D.L. Gruol Interleukin-6, beta-amyloid peptide and NMDA interactions in rat cortical neurons J. Neuroimmunol. 139 2003 51 57
    • (2003) J. Neuroimmunol. , vol.139 , pp. 51-57
    • Qiu, Z.1    Gruol, D.L.2
  • 42
    • 0028812570 scopus 로고
    • Interleukin-6 selectively enhances the intracellular calcium response to NMDA in developing CNS neurons
    • Z. Qiu, K.L. Parsons, and D.L. Gruol Interleukin-6 selectively enhances the intracellular calcium response to NMDA in developing CNS neurons J. Neurosci. 15 1995 6688 6699
    • (1995) J. Neurosci. , vol.15 , pp. 6688-6699
    • Qiu, Z.1    Parsons, K.L.2    Gruol, D.L.3
  • 43
    • 0032535026 scopus 로고    scopus 로고
    • Chronic interleukin-6 alters NMDA receptor-mediated responses and enhances neurotoxicity in developing CNS neurons
    • Z. Qiu, D.D. Sweeney, J.G. Netzeband, and D.L. Gruol Chronic interleukin-6 alters NMDA receptor-mediated responses and enhances neurotoxicity in developing CNS neurons J. Neurosci. 18 1998 10445 10456
    • (1998) J. Neurosci. , vol.18 , pp. 10445-10456
    • Qiu, Z.1    Sweeney, D.D.2    Netzeband, J.G.3    Gruol, D.L.4
  • 44
    • 0027385331 scopus 로고
    • The developmental onset of NMDA receptor channel activity during neuronal migration
    • D. Rossi, and T.N. Slater The developmental onset of NMDA receptor channel activity during neuronal migration Neuropharmacology 32 1993 1239 1248
    • (1993) Neuropharmacology , vol.32 , pp. 1239-1248
    • Rossi, D.1    Slater, T.N.2
  • 46
    • 0027423232 scopus 로고
    • Cellular localization of interleukin-6 mRNA and interleukin-6 receptor mRNA in rat brain
    • B. Schobitz, E.R. De Kloet, W. Sutanto, and F. Holsboer Cellular localization of interleukin-6 mRNA and interleukin-6 receptor mRNA in rat brain Eur. J. Neurosci. 5 1993 1426 1435
    • (1993) Eur. J. Neurosci. , vol.5 , pp. 1426-1435
    • Schobitz, B.1    De Kloet, E.R.2    Sutanto, W.3    Holsboer, F.4
  • 47
    • 0025139268 scopus 로고
    • Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: Role of the glutamate receptor responsive to N-methyl-d-aspartate
    • M. Schramm, S. Eimerl, and E. Costa Serum and depolarizing agents cause acute neurotoxicity in cultured cerebellar granule cells: role of the glutamate receptor responsive to N-methyl-d-aspartate Proc. Natl. Acad. Sci. U. S. A. 87 1990 1193 1197
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 1193-1197
    • Schramm, M.1    Eimerl, S.2    Costa, E.3
  • 48
    • 0028298627 scopus 로고
    • Site-specific hippocampal pathophysiology due to cerebral overexpression of interleukin-6 in transgenic mice
    • S.C. Steffensen, I.L. Campbell, and S.J. Henriksen Site-specific hippocampal pathophysiology due to cerebral overexpression of interleukin-6 in transgenic mice Brain Res. 652 1994 149 153
    • (1994) Brain Res. , vol.652 , pp. 149-153
    • Steffensen, S.C.1    Campbell, I.L.2    Henriksen, S.J.3
  • 49
    • 0026781413 scopus 로고
    • Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons
    • S. Toulmond, X. Vige, D. Fage, and J. Benavides Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons Neurosci. Lett. 144 1992 49 52
    • (1992) Neurosci. Lett. , vol.144 , pp. 49-52
    • Toulmond, S.1    Vige, X.2    Fage, D.3    Benavides, J.4
  • 50
    • 0037079993 scopus 로고    scopus 로고
    • Reduced hippocampal neurogenesis in adult transgeinc mice with chronic astrocyte production of interleukin-6
    • L. Vallieres, I.L. Campbell, F.H. Gage, and P.E. Swanchenko Reduced hippocampal neurogenesis in adult transgeinc mice with chronic astrocyte production of interleukin-6 J. Neurosci. 22 2002 486 492
    • (2002) J. Neurosci. , vol.22 , pp. 486-492
    • Vallieres, L.1    Campbell, I.L.2    Gage, F.H.3    Swanchenko, P.E.4
  • 51
    • 0024565073 scopus 로고
    • Endogenous amino acid release from cultured cerebellar neuronal cells: Effect of tetanus toxin on glutamate release
    • B.J. Van-Vliet, M. Sebben, A. Dumuis, J. Grabion, J. Bockaert, and J.-P. Pin Endogenous amino acid release from cultured cerebellar neuronal cells: effect of tetanus toxin on glutamate release J. Neurochem. 52 1989 1229 1239
    • (1989) J. Neurochem. , vol.52 , pp. 1229-1239
    • Van-Vliet, B.J.1    Sebben, M.2    Dumuis, A.3    Grabion, J.4    Bockaert, J.5    Pin, J.-P.6
  • 52
    • 0028884420 scopus 로고
    • Screening of interleukins for survival promoting effects on cultured mesencephalic dopaminergic neurons from embryonic rat brain
    • R. von Coelln, K. Unsicker, and T.B. Kristiansen Screening of interleukins for survival promoting effects on cultured mesencephalic dopaminergic neurons from embryonic rat brain Dev. Brain Res. 89 1995 150 154
    • (1995) Dev. Brain Res. , vol.89 , pp. 150-154
    • Von Coelln, R.1    Unsicker, K.2    Kristiansen, T.B.3
  • 54
    • 0030046508 scopus 로고    scopus 로고
    • Life, death, and the pursuit of apoptosis
    • E. White Life, death, and the pursuit of apoptosis Genes Dev. 10 1996 1 15
    • (1996) Genes Dev. , vol.10 , pp. 1-15
    • White, E.1
  • 55
    • 0027495786 scopus 로고
    • In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum
    • K.A. Wood, B. Dipasquale, and R.J. Youle In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum Neuron 11 1993 621 632
    • (1993) Neuron , vol.11 , pp. 621-632
    • Wood, K.A.1    Dipasquale, B.2    Youle, R.J.3
  • 56
    • 0028266972 scopus 로고
    • Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death
    • M. Yamada, and H. Htanaka Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death Brain Res. 643 1994 173 180
    • (1994) Brain Res. , vol.643 , pp. 173-180
    • Yamada, M.1    Htanaka, H.2
  • 57
    • 0006444685 scopus 로고    scopus 로고
    • Cultured cerebellar granule neurons as a model of neuronal apoptosis
    • G.-M. Yan, and S. Paul Cultured cerebellar granule neurons as a model of neuronal apoptosis Neuromethods 29 1997 47 66
    • (1997) Neuromethods , vol.29 , pp. 47-66
    • Yan, G.-M.1    Paul, S.2
  • 58
    • 0030872032 scopus 로고    scopus 로고
    • Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy
    • B.H. Yoon, J.K. Jun, R. Romero, K.H. Park, R. Gomez, J.H. Choi, and I.O. Kim Amniotic fluid inflammatory cytokines (interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha), neonatal brain white matter lesions, and cerebral palsy Am. J. Obstet. Gynecol. 177 1997 19 26
    • (1997) Am. J. Obstet. Gynecol. , vol.177 , pp. 19-26
    • Yoon, B.H.1    Jun, J.K.2    Romero, R.3    Park, K.H.4    Gomez, R.5    Choi, J.H.6    Kim, I.O.7
  • 59
    • 0030883944 scopus 로고    scopus 로고
    • High expression of tumor necrosis factor-a and interleukin-6 in periventricular leukomalacia
    • B.H. Yoon, R. Romero, C.J. Kim, J.N. Koo, G. Choe, H.C. Syn, and J.G. Chi High expression of tumor necrosis factor-a and interleukin-6 in periventricular leukomalacia Am. J. Obstet. Gynecol. 177 1997 406 411
    • (1997) Am. J. Obstet. Gynecol. , vol.177 , pp. 406-411
    • Yoon, B.H.1    Romero, R.2    Kim, C.J.3    Koo, J.N.4    Choe, G.5    Syn, H.C.6    Chi, J.G.7
  • 60
    • 0034037785 scopus 로고    scopus 로고
    • Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years
    • B.H. Yoon, R. Romero, J.S. Park, C.J. Kim, S.H. Kim, J.H. Choi, and T.R. Han Fetal exposure to an intra-amniotic inflammation and the development of cerebral palsy at the age of three years Am. J. Obstet. Gynecol. 182 2000 675 681
    • (2000) Am. J. Obstet. Gynecol. , vol.182 , pp. 675-681
    • Yoon, B.H.1    Romero, R.2    Park, J.S.3    Kim, C.J.4    Kim, S.H.5    Choi, J.H.6    Han, T.R.7
  • 61
    • 0032528151 scopus 로고    scopus 로고
    • Glutamate receptor targeting to synaptic populations on Purkinje cells is developmentally regulated
    • H.-M. Zhao, R.J. Wenthold, and R.S. Petralia Glutamate receptor targeting to synaptic populations on Purkinje cells is developmentally regulated J. Neurosci. 18 1998 5517 5528
    • (1998) J. Neurosci. , vol.18 , pp. 5517-5528
    • Zhao, H.-M.1    Wenthold, R.J.2    Petralia, R.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.