Evidence of gene conversion in the evolutionary process of the codon 41/42 (-CTTT) mutation causing β-thalassemia in southern China

Journal of Molecular Evolution

Volumn 66, Issue 5, 2008, Pages 436-445

  Zhang, Wen ^a   Cai, Wang Wei ^a,b   Zhou, Wei Ping ^c,d,e   Li, Hai Peng ^f   Li, Liang ^a   Yan, Wei ^a   Deng, Qin Kai ^a   Zhang, Ya Ping ^c,d   Fu, Yun Xin ^g   Xu, Xiang Min ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b HAINAN MEDICAL UNIVERSITY   (China)

^c KUNMING INSTITUTE OF ZOOLOGY   (China)

^d YUNNAN UNIVERSITY   (China)

^e UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^f UNIVERSITY OF COLOGNE   (Germany)

^g UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Thalassemia; Balancing selection; Evolutionary process; Gene conversion; Malaria

Indexed keywords

BETA GLOBIN;

ALLELE; ARTICLE; BETA THALASSEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; GENE CLUSTER; GENE CONVERSION; GENE DELETION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GLOBIN GENE; HETEROZYGOSITY; HUMAN; MOLECULAR EVOLUTION; NATURAL SELECTION; POPULATION GENETICS;

BASE SEQUENCE; BETA-THALASSEMIA; CHINA; CODON; DNA MUTATIONAL ANALYSIS; EVOLUTION, MOLECULAR; GENE CONVERSION; GLOBINS; HAPLOTYPES; HUMANS; MODELS, GENETIC; MUTATION; POLYMORPHISM, GENETIC; SEQUENCE DELETION; VARIATION (GENETICS);

EID: 44249123251     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00239-008-9096-2     Document Type: Article

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