The β-globin recombinational hotspot reduces the effects of strong selection around HbC, a recently arisen mutation providing resistance to malaria

American Journal of Human Genetics

Volumn 77, Issue 4, 2005, Pages 637-642

  Wood, Elizabeth T ^a,b   Stover, Daryn A ^a   Slatkin, Montgomery ^c   Nachman, Michael W ^b   Hammer, Michael F ^a,b  

^a UNIVERSITY OF ARIZONA   (United States)

^b University of Arizona   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; HEMOGLOBIN C;

ALLELE; ARTICLE; CALCULATION; CHROMOSOME; CROSSING OVER; GENE CONVERSION; GENE LINKAGE DISEQUILIBRIUM; GENE SEQUENCE; GENETIC RECOMBINATION; GENETIC SELECTION; GENETIC VARIABILITY; HUMAN; HUMAN GENOME; INFECTION RESISTANCE; LINKAGE ANALYSIS; MALARIA; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL; RECOMBINATIONAL HOTSPOT; SEQUENCE ANALYSIS;

EID: 25444507435     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/491748     Document Type: Article

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