An estrogen receptor-α knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo

Endocrinology

Volumn 149, Issue 6, 2008, Pages 2970-2979

  Sinkevicius, Kerstin W ^a   Burdette, Joanna E ^c   Woloszyn, Karolina ^a   Hewitt, Sylvia C ^d   Hamilton, Katherine ^d   Sugg, Sonia L ^e   Temple, Karla A ^b   Wondisford, Fredric E ^f   Korach, Kenneth S ^d   Woodruff, Teresa K ^g   Greene, Geoffrey L ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e UNIVERSITY OF IOWA   (United States)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3,5 TRIS(4 HYDROXYPHENYL) 4 PROPYLPYRAZOLE; DIETHYLSTILBESTROL; ESTROGEN RECEPTOR ALPHA; GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENTIATION;

ADENOCARCINOMA; ADIPOSE TISSUE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE, TUMOR; CLONING, MOLECULAR; DIETHYLSTILBESTROL; ENDOMETRIAL NEOPLASMS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; FOLLICLE STIMULATING HORMONE; GENOTYPE; HUMANS; LIGANDS; LUTEINIZING HORMONE; MAMMARY GLANDS, ANIMAL; MICE; MUTATION; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UTERUS;

EID: 44249102300     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-1526     Document Type: Article

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