-
1
-
-
35949002429
-
Malignant astrocytic glioma: Genetics, biology, and paths to treatment
-
Furnari FB, Fenton T, Bachoo RM et al.: Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev. 21(21), 2683-2710 (2007).
-
(2007)
Genes Dev
, vol.21
, Issue.21
, pp. 2683-2710
-
-
Furnari, F.B.1
Fenton, T.2
Bachoo, R.M.3
-
2
-
-
34547113747
-
Tumor growth need not be driven by rare cancer stem cells
-
Kelly PN, Dakic A. Adams JM, Nutt SL, Strasser A: Tumor growth need not be driven by rare cancer stem cells. Science 317, 337 (2007).
-
(2007)
Science
, vol.317
, pp. 337
-
-
Kelly, P.N.1
Dakic, A.2
Adams, J.M.3
Nutt, S.L.4
Strasser, A.5
-
4
-
-
33947433676
-
Cancer stem cells: At the headwaters of tumor development
-
Ward RJ, Dirks PB: Cancer stem cells: at the headwaters of tumor development. Annu. Rev. Pathol. 2, 175-189 (2007).
-
(2007)
Annu. Rev. Pathol
, vol.2
, pp. 175-189
-
-
Ward, R.J.1
Dirks, P.B.2
-
5
-
-
35148888629
-
Cancer stem cells in radiation resistance
-
Rich JN: Cancer stem cells in radiation resistance. Cancer Res. 67(19), 8980-8984 (2007).
-
(2007)
Cancer Res
, vol.67
, Issue.19
, pp. 8980-8984
-
-
Rich, J.N.1
-
7
-
-
26644435531
-
Radial glia cells are candidate stem cells of ependymoma
-
Taylor MD, Poppleton H, Fuiler C et al.: Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 8(4), 323-335 (2005).
-
(2005)
Cancer Cell
, vol.8
, Issue.4
, pp. 323-335
-
-
Taylor, M.D.1
Poppleton, H.2
Fuiler, C.3
-
8
-
-
23644443053
-
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
-
Zhu Y, Guignard F, Zhao D et al.: Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma. Cancer Cell 8(2), 119-130 (2005).
-
(2005)
Cancer Cell
, vol.8
, Issue.2
, pp. 119-130
-
-
Zhu, Y.1
Guignard, F.2
Zhao, D.3
-
9
-
-
0034020459
-
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
-
Holland EC, Celestino J, Dai C, Schaefer L, Sawaya RE, Fuller GN: Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nat. Genet. 25(1), 55-57 (2000).
-
(2000)
Nat. Genet
, vol.25
, Issue.1
, pp. 55-57
-
-
Holland, E.C.1
Celestino, J.2
Dai, C.3
Schaefer, L.4
Sawaya, R.E.5
Fuller, G.N.6
-
10
-
-
33846815345
-
Olig2-regulated lineage-restricted pathway controls replitation competence in neural stem cells and malignant glioma
-
Ligon KL, Huillard E, Mehta S et al.: Olig2-regulated lineage-restricted pathway controls replitation competence in neural stem cells and malignant glioma. Neuron 53(4), 503-517 (2007).
-
(2007)
Neuron
, vol.53
, Issue.4
, pp. 503-517
-
-
Ligon, K.L.1
Huillard, E.2
Mehta, S.3
-
11
-
-
19044397160
-
Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
-
Bachoo RM, Maher EA, Ligon KL et al.: Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell 1, 269-277 (2002).
-
(2002)
Cancer Cell
, vol.1
, pp. 269-277
-
-
Bachoo, R.M.1
Maher, E.A.2
Ligon, K.L.3
-
12
-
-
0036791177
-
Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt
-
Uhrbom L, Dai C, Celestino JC, Rosenblum MK, Fuller GN, Holland EC: Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt. Cancer Res. 62(19), 5551-5558 (2002).
-
(2002)
Cancer Res
, vol.62
, Issue.19
, pp. 5551-5558
-
-
Uhrbom, L.1
Dai, C.2
Celestino, J.C.3
Rosenblum, M.K.4
Fuller, G.N.5
Holland, E.C.6
-
13
-
-
16844370694
-
Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis
-
Ubrbom L, Kastemar M, Johansson FK, Westermark B, Holland EC: Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis. Cancer Res. 65(6), 2065-2069 (2005).
-
(2005)
Cancer Res
, vol.65
, Issue.6
, pp. 2065-2069
-
-
Ubrbom, L.1
Kastemar, M.2
Johansson, F.K.3
Westermark, B.4
Holland, E.C.5
-
14
-
-
35148840173
-
BMI1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma
-
Bruggeman SW, Hulsman D, Tanger E et al.: BMI1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma. Cancer Cell 12(4), 328-341 (2007).
-
(2007)
Cancer Cell
, vol.12
, Issue.4
, pp. 328-341
-
-
Bruggeman, S.W.1
Hulsman, D.2
Tanger, E.3
-
15
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF, Weissman IL: Stem cells, cancer, and cancer stem cells. Nature 414, 105-111 (2001).
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
17
-
-
0034687840
-
Direct isolation of human central nervous system stem cells
-
Uchida N, Buck DW, He D et al.: Direct isolation of human central nervous system stem cells. Proc. Natl Acad Sci. USA 97(26), 14720-14725 (2000).
-
(2000)
Proc. Natl Acad Sci. USA
, vol.97
, Issue.26
, pp. 14720-14725
-
-
Uchida, N.1
Buck, D.W.2
He, D.3
-
18
-
-
9244241576
-
Identification of Human brain rumour initiating cells
-
Singh SK, Hawkins C, Clarke ID et al.: Identification of Human brain rumour initiating cells. Nature 432, 396-401 (2004).
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
-
19
-
-
0141842674
-
Identification of a cancer stem cell in human brain Tumors
-
Singh SK, Clarke ID, Terasaki M et al.: Identification of a cancer stem cell in human brain Tumors. Cancer Res. 63(18), 5821-5828 (2003).
-
(2003)
Cancer Res
, vol.63
, Issue.18
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
-
20
-
-
4944250781
-
Isolation and characterization of rumorigenic, stem-like neural precursors from human glioblastoma
-
Galh R, Binda E, Orfanelli U et al.: Isolation and characterization of rumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res. 64(19), 7011-7021 (2004).
-
(2004)
Cancer Res
, vol.64
, Issue.19
, pp. 7011-7021
-
-
Galh, R.1
Binda, E.2
Orfanelli, U.3
-
21
-
-
0036737914
-
Human cortical glial rumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
-
Ignatova TN, Kukekov VG, Laywell ED, Suslov ON, Vrionis FD, Steindler DA. Human cortical glial rumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia 39(3), 193-206 (2002).
-
(2002)
Glia
, vol.39
, Issue.3
, pp. 193-206
-
-
Ignatova, T.N.1
Kukekov, V.G.2
Laywell, E.D.3
Suslov, O.N.4
Vrionis, F.D.5
Steindler, D.A.6
-
22
-
-
0344735881
-
-
Hemmati HD, Nakano i, Lazareff JA et al.: Cancerous stem cells can arise from pediatric brain rumors. Proc. Natl Acad. Sci. USA 100(25), 15178-15183 (2003).
-
Hemmati HD, Nakano i, Lazareff JA et al.: Cancerous stem cells can arise from pediatric brain rumors. Proc. Natl Acad. Sci. USA 100(25), 15178-15183 (2003).
-
-
-
-
23
-
-
33646358694
-
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
-
Lee J, Kotliarova S, Kotliarov Y et al.: Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 9(5), 391-403 (2006).
-
(2006)
Cancer Cell
, vol.9
, Issue.5
, pp. 391-403
-
-
Lee, J.1
Kotliarova, S.2
Kotliarov, Y.3
-
24
-
-
11244293572
-
Isolation of cancer stem cells from adult glioblastoma multiforme
-
Yuan X, Curtin J, Xiong Y et al.: Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene 23(58), 9392-9400 (2004).
-
(2004)
Oncogene
, vol.23
, Issue.58
, pp. 9392-9400
-
-
Yuan, X.1
Curtin, J.2
Xiong, Y.3
-
25
-
-
33748990080
-
Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology
-
Singec I, Knoth R, Meyer RP et al.: Defining the actual sensitivity and specificity of the neurosphere assay in stem cell biology. Nat. Methods 3(10), 801-806 (2006).
-
(2006)
Nat. Methods
, vol.3
, Issue.10
, pp. 801-806
-
-
Singec, I.1
Knoth, R.2
Meyer, R.P.3
-
26
-
-
0028091194
-
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice, 367, 645-A8
-
Lapidot T, Shard C, Vormoor J et al.: A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367, 645-(A8 (1994).
-
(1994)
Nature
-
-
Lapidot, T.1
Shard, C.2
Vormoor, J.3
-
27
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE: Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med. 3, 730-737 (1997).
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
28
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez; A, Morrison SJ, Clarke MF: Prospective identification of tumorigenic breast cancer cells. Proc. Natl Acad Sci. USA 100, 3983-3988. (2003).
-
(2003)
Proc. Natl Acad Sci. USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
29
-
-
34250794574
-
CD 133 is not present on neurogenic astrocytes in the adult subventricular zone, but on embryonic neural stem cells, ependymal cells, and glioblastoma cells
-
Pfenninger CV, Roschupkina T, Hertwig F et al.: CD 133 is not present on neurogenic astrocytes in the adult subventricular zone, but on embryonic neural stem cells, ependymal cells, and glioblastoma cells, Cancer Res. 67(12), 5727-5736 (2007).
-
(2007)
Cancer Res
, vol.67
, Issue.12
, pp. 5727-5736
-
-
Pfenninger, C.V.1
Roschupkina, T.2
Hertwig, F.3
-
30
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao S, Wu Q, McLendon RE et al.: Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444, 756-760 (2006).
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
-
31
-
-
34249332411
-
CD133' and CD133 glioblastoma-derived cancer stem cells show differential growth, characteristics and molecular profiles
-
Beier D, Hau P, Proescholdt M et al.: CD133' and CD133 glioblastoma-derived cancer stem cells show differential growth, characteristics and molecular profiles. Cancer Res. 67, 4010-4015 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 4010-4015
-
-
Beier, D.1
Hau, P.2
Proescholdt, M.3
-
32
-
-
34248547533
-
Most C6 cells are cancer stem cells: Evidence from clonal and population analyses
-
Zheng X, Shen G, Yang X, Liu W. Most C6 cells are cancer stem cells: evidence from clonal and population analyses. Cancer Res. 67(8), 3691-3697 (2007).
-
(2007)
Cancer Res
, vol.67
, Issue.8
, pp. 3691-3697
-
-
Zheng, X.1
Shen, G.2
Yang, X.3
Liu, W.4
-
33
-
-
38349075007
-
CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells
-
Wang J, Sakariassen PØ, Tsinkalovsky O et al.: CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. Int. J. Cancer 122(4), 761-768 (2008).
-
(2008)
Int. J. Cancer
, vol.122
, Issue.4
, pp. 761-768
-
-
Wang, J.1
Sakariassen, P.2
Tsinkalovsky, O.3
-
34
-
-
34247543119
-
IQGAPI regulates adult neural progenitors in vivo and vascular endothelial growth factor-triggered neural progenitor migration in vitro
-
Balend L, Saoudi Y, Grunwald D et al.: IQGAPI regulates adult neural progenitors in vivo and vascular endothelial growth factor-triggered neural progenitor migration in vitro. J Neurosci. 27(17), 4716-4724 (2007).
-
(2007)
J Neurosci
, vol.27
, Issue.17
, pp. 4716-4724
-
-
Balend, L.1
Saoudi, Y.2
Grunwald, D.3
-
35
-
-
33749455736
-
IQGAPI protein specifies amplifying cancer cells in glioblastoma multiforme
-
Balenci L, Clarke ID, Dirks PB et al.: IQGAPI protein specifies amplifying cancer cells in glioblastoma multiforme. Cancer Res. 66(18), 9074-90782 (2006).
-
(2006)
Cancer Res
, vol.66
, Issue.18
, pp. 9074-90782
-
-
Balenci, L.1
Clarke, I.D.2
Dirks, P.B.3
-
36
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA: The hallmarks of cancer. Cell 100, 57-76 (2000).
-
(2000)
Cell
, vol.100
, pp. 57-76
-
-
Hanahan, D.1
Weinberg, R.A.2
-
37
-
-
33846237601
-
HEDGEHOG-GLII signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
-
Clement V, Sanchez P, de Tribolet N, Radovanovic I, Ruiz i Altaba A: HEDGEHOG-GLII signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity. Curr. Biol. 17(2), 165-172 (2007).
-
(2007)
Curr. Biol
, vol.17
, Issue.2
, pp. 165-172
-
-
Clement, V.1
Sanchez, P.2
de Tribolet, N.3
Radovanovic, I.4
Ruiz i Altaba, A.5
-
38
-
-
35348837163
-
Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma
-
Bar EE, Chaudhry A, Lin A et al.: Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Stem Cells 25(10), 2524-2533 (2007).
-
(2007)
Stem Cells
, vol.25
, Issue.10
, pp. 2524-2533
-
-
Bar, E.E.1
Chaudhry, A.2
Lin, A.3
-
39
-
-
33747874155
-
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
-
Fan X, Matsui W, Khaki L et al.: Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res. 66, 7445-7452 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 7445-7452
-
-
Fan, X.1
Matsui, W.2
Khaki, L.3
-
40
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
Molofsky AV, Pardal R, Iwashita T et al.: Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425, 962-967 (2003).
-
(2003)
Nature
, vol.425
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
-
41
-
-
33845610993
-
Bone morphogenetic proteins inhibit the tumaorigenic potential of human brain tumour initiating cells
-
Piccirillo SG, Reynolds BA, Zanetti N et al.: Bone morphogenetic proteins inhibit the tumaorigenic potential of human brain tumour initiating cells. Nature 444(7120), 761-765 (2006).
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 761-765
-
-
Piccirillo, S.G.1
Reynolds, B.A.2
Zanetti, N.3
-
42
-
-
34548162850
-
Ligand-dependent activation of the hedgehog pathway in glioma progenitor cells
-
2907
-
Ehtesham M, Sarangi A, Valadez JG et al.: Ligand-dependent activation of the hedgehog pathway in glioma progenitor cells. Oncogene 26(39), 5752-5761 (2907).
-
Oncogene
, vol.26
, Issue.39
, pp. 5752-5761
-
-
Ehtesham, M.1
Sarangi, A.2
Valadez, J.G.3
-
43
-
-
37349067098
-
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
-
Lee J, Son MJ, Woolard K et al.: Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell 13(1), 69-810 (2008).
-
(2008)
Cancer Cell
, vol.13
, Issue.1
, pp. 69-810
-
-
Lee, J.1
Son, M.J.2
Woolard, K.3
-
44
-
-
38049090322
-
Maternal embryonic leucine zipper kinase is a key regulator of die proliferation of malignant brain tumors, including brain tumor stem cells
-
Nakano I, Masterman-Smith M, Saigusa K et al.: Maternal embryonic leucine zipper kinase is a key regulator of die proliferation of malignant brain tumors, including brain tumor stem cells. J. Neurosci. Res. 86(1), 48-60 (2007).
-
(2007)
J. Neurosci. Res
, vol.86
, Issue.1
, pp. 48-60
-
-
Nakano, I.1
Masterman-Smith, M.2
Saigusa, K.3
-
45
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ et al.: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352(10), 987-996 (2005).
-
(2005)
N. Engl. J. Med
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
47
-
-
33845671339
-
Analysis of gene expression and chemoresistance of CD133′ cancer stem cells in glioblastoma
-
Liu G, Yuan X, Zeng Z et al.: Analysis of gene expression and chemoresistance of CD133′ cancer stem cells in glioblastoma. Mol. Cancer 5, 67 (2006).
-
(2006)
Mol. Cancer
, vol.5
, pp. 67
-
-
Liu, G.1
Yuan, X.2
Zeng, Z.3
-
48
-
-
34248550985
-
Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors
-
Folkins C, Man S, Xu P, Shaked Y, Hicklin DJ, Kerbel RS: Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors. Cancer Res. 67(8), 3560-3564(2007).
-
(2007)
Cancer Res
, vol.67
, Issue.8
, pp. 3560-3564
-
-
Folkins, C.1
Man, S.2
Xu, P.3
Shaked, Y.4
Hicklin, D.J.5
Kerbel, R.S.6
-
49
-
-
34648821254
-
Making a tumour's bed: Glioblastoma stem cells and the vascular niche
-
Gilbertson RJ, Rich JN: Making a tumour's bed: glioblastoma stem cells and the vascular niche. Nat. Rev. Cancer 7(10), 733-736 (2007).
-
(2007)
Nat. Rev. Cancer
, vol.7
, Issue.10
, pp. 733-736
-
-
Gilbertson, R.J.1
Rich, J.N.2
-
50
-
-
33748051406
-
Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor
-
Bao S, Wu Q, Sathornsumetee S et al.: Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res. 66, 7843-7848 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 7843-7848
-
-
Bao, S.1
Wu, Q.2
Sathornsumetee, S.3
-
51
-
-
33750306612
-
Most early disseminated cancer cells detected in bone marrow of brcast cancer patients have a putative breast cancer stem cell phenotype
-
Balic M, Lin H, Young L et al.: Most early disseminated cancer cells detected in bone marrow of brcast cancer patients have a putative breast cancer stem cell phenotype. Clin. Cancer Res. 12(19), 5615-56121 (2006).
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.19
, pp. 5615-56121
-
-
Balic, M.1
Lin, H.2
Young, L.3
-
52
-
-
34548455927
-
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
-
Hermann PC, Huber SL, Herrler T et al.: Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1, 313-323 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 313-323
-
-
Hermann, P.C.1
Huber, S.L.2
Herrler, T.3
-
53
-
-
34447632643
-
Angiogenesis in brain turnouts
-
Jain RK, di Tomaso, E, Duda DG, Loeffler JS, Sorensen AG, Batchelor TT: Angiogenesis in brain turnouts. Nat. Rev. Neurosci. 8(8), 610-622 (2007).
-
(2007)
Nat. Rev. Neurosci
, vol.8
, Issue.8
, pp. 610-622
-
-
Jain, R.K.1
di Tomaso, E.2
Duda, D.G.3
Loeffler, J.S.4
Sorensen, A.G.5
Batchelor, T.T.6
-
54
-
-
36049037819
-
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
-
Vredenburgh JJ, Desjardins A, Herndon JE 2nd et al.: Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J. Clin. Oncol. 25(30), 4722-4729 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.30
, pp. 4722-4729
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon 2nd, J.E.3
-
55
-
-
33947191055
-
Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
-
Vredenburgh JJ, Desjardins A, Herndon JE 2nd et al.: Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin. Cancer Res. 13(4), 1253-1259 (2007).
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.4
, pp. 1253-1259
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon 2nd, J.E.3
-
56
-
-
33846149645
-
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
-
Bauchelor TT, Sorensen AG, di Tomaso E et al.: AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 11(1), 83-95 (2007).
-
(2007)
Cancer Cell
, vol.11
, Issue.1
, pp. 83-95
-
-
Bauchelor, T.T.1
Sorensen, A.G.2
di Tomaso, E.3
-
57
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C, Poppleton H, Kocak M et al.: A perivascular niche for brain tumor stem cells. Cancer Cell 11, 69-82 (2007).
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
-
58
-
-
33646260685
-
Using molecular information to guide brain tumor therapy
-
Mischel PS, Cloughesy T: Using molecular information to guide brain tumor therapy. Nat. Clin. Pract. Neurol. 2(5), 232-233 (2006).
-
(2006)
Nat. Clin. Pract. Neurol
, vol.2
, Issue.5
, pp. 232-233
-
-
Mischel, P.S.1
Cloughesy, T.2
-
59
-
-
33645732219
-
Molecular pathology of malignant gliomas
-
Louis DN: Molecular pathology of malignant gliomas. Annu. Rev. Pathol. 1, 97-117 (2006).
-
(2006)
Annu. Rev. Pathol
, vol.1
, pp. 97-117
-
-
Louis, D.N.1
-
60
-
-
33846425793
-
The prognostic role of a gene signature from tumorigenic breast-cancer cells
-
Liu R, Wang X, Chen GY et al.: The prognostic role of a gene signature from tumorigenic breast-cancer cells. N. Engl. J. Med. 356, 217-226 (2007).
-
(2007)
N. Engl. J. Med
, vol.356
, pp. 217-226
-
-
Liu, R.1
Wang, X.2
Chen, G.Y.3
-
61
-
-
40749155451
-
Stem cell marker CD133 affects clinical outcome in glioma patients
-
Zeppernick F, Ahmadi R, Campos B et al.: Stem cell marker CD133 affects clinical outcome in glioma patients. Clin. Cancer Res. 14(1), 123-129 (2008).
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.1
, pp. 123-129
-
-
Zeppernick, F.1
Ahmadi, R.2
Campos, B.3
-
62
-
-
34250306257
-
Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
-
Ho MM, Ng AV, Lam S, Hung JY: Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res. 67, 4827-4833 (2007).
-
(2007)
Cancer Res
, vol.67
, pp. 4827-4833
-
-
Ho, M.M.1
Ng, A.V.2
Lam, S.3
Hung, J.Y.4
-
63
-
-
4644306516
-
A distinct 'side population' of cells with high drug efflux capacity in human tumor cells
-
Hirschmann-Jax C, Foster AE, Wulf GG et al.: A distinct 'side population' of cells with high drug efflux capacity in human tumor cells. Proc. Natl. Acad. Sci. USA 101, 14228-14233 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 14228-14233
-
-
Hirschmann-Jax, C.1
Foster, A.E.2
Wulf, G.G.3
-
64
-
-
0034795256
-
The ABC transporter Bcrp1/ ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
Zhou S, Schuetz JD, Bunting KD et al.: The ABC transporter Bcrp1/ ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat. Med. 7, 1028-1034 (2001).
-
(2001)
Nat. Med
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
-
65
-
-
0025799513
-
Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
-
Chaudhary PM, Roninson IB: Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 66, 85-94 (1991).
-
(1991)
Cell
, vol.66
, pp. 85-94
-
-
Chaudhary, P.M.1
Roninson, I.B.2
-
66
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
Ginestier C, Hur MH, Charafe-Jauffret E et al.: ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1, 555-567 (2007).
-
(2007)
Cell Stem Cell
, vol.1
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
-
67
-
-
20344364875
-
Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples
-
Pearce DJ, Taussig D, Simpson C et al.: Characterization of cells with a high aldehyde dehydrogenase activity from cord blood and acute myeloid leukemia samples. Stem Cells 23, 752-760 (2005).
-
(2005)
Stem Cells
, vol.23
, pp. 752-760
-
-
Pearce, D.J.1
Taussig, D.2
Simpson, C.3
-
68
-
-
34247217907
-
Chemical genetics reveals a complex functional ground state of neural stem cells
-
Diamandis P, Wildenhain J, Clarke ID et al.: Chemical genetics reveals a complex functional ground state of neural stem cells. Nat. Chem. Biol. 3(5), 268-273 (2007).
-
(2007)
Nat. Chem. Biol
, vol.3
, Issue.5
, pp. 268-273
-
-
Diamandis, P.1
Wildenhain, J.2
Clarke, I.D.3
-
69
-
-
33749515476
-
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
-
Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE: Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat. Med. 12, 1167-1174 (2006).
-
(2006)
Nat. Med
, vol.12
, pp. 1167-1174
-
-
Jin, L.1
Hope, K.J.2
Zhai, Q.3
Smadja-Joffe, F.4
Dick, J.E.5
-
70
-
-
33751297619
-
Neurospheres enriched in cancer stem-like cells are highly effective in eliciting a dendritic cell-mediated immune response against malignant gliomas
-
Pellegatta S, Poliani PL, Corno D et al.: Neurospheres enriched in cancer stem-like cells are highly effective in eliciting a dendritic cell-mediated immune response against malignant gliomas. Cancer Res. 66, 10247-10252 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 10247-10252
-
-
Pellegatta, S.1
Poliani, P.L.2
Corno, D.3
-
71
-
-
34748880650
-
Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: Role of autophagic cell death
-
Jiang H, Gomez-Manzano C, Aoki H et al.: Examination of the therapeutic potential of Delta-24-RGD in brain tumor stem cells: role of autophagic cell death. J. Natl. Cancer Inst. 99(18), 1410-1414 (2007).
-
(2007)
J. Natl. Cancer Inst
, vol.99
, Issue.18
, pp. 1410-1414
-
-
Jiang, H.1
Gomez-Manzano, C.2
Aoki, H.3
-
72
-
-
33750706917
-
Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
-
Roy NS, Cleren C, Singh SK, Yang L, Beal MF, Goldman SA: Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nat Med. 12(11), 1259-1268 (2006).
-
(2006)
Nat Med
, vol.12
, Issue.11
, pp. 1259-1268
-
-
Roy, N.S.1
Cleren, C.2
Singh, S.K.3
Yang, L.4
Beal, M.F.5
Goldman, S.A.6
-
73
-
-
33644560281
-
Cancer stem cells: An old idea - a paradigm shift
-
Wicha MS, Liu S, Dontu G: Cancer stem cells: an old idea - a paradigm shift. Cancer Res. 66, 1883-1890 (2006).
-
(2006)
Cancer Res
, vol.66
, pp. 1883-1890
-
-
Wicha, M.S.1
Liu, S.2
Dontu, G.3
|