Two components of the Myb complex, DMyb and Mip130, are specifically associated with euchromatin and degraded during prometaphase throughout development

Mechanisms of Development

Volumn 125, Issue 7, 2008, Pages 646-661

  Scaria, George S ^a   Ramsay, Gary ^a   Katzen, Alisa L ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

APC C; Cell cycle; Dm myb; DMyb; Drosophila; Mitosis; Myb; Myb complex; Proto oncogene

Indexed keywords

ADAPTOR PROTEIN; ALPHA TUBULIN; CYCLIN A; DIMETHYL SULFOXIDE; MESSENGER RNA; PROTEIN DMYB; PROTEIN MIP130; PROTEIN MYB; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL CYCLE S PHASE; CELL MATURATION; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; EUCHROMATIN; GENE; LARVA; MITOSIS; MYB GENE; NONHUMAN; POLYPLOIDY; PRIORITY JOURNAL; PROMETAPHASE; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; REGULATORY MECHANISM;

ANIMALS; CARRIER PROTEINS; CELL CYCLE PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EUCHROMATIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; PROMETAPHASE; PROTO-ONCOGENE PROTEINS C-MYB;

MAMMALIA;

EID: 43949088146     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mod.2008.02.005     Document Type: Article

References (63)

1. Adler P.N., and MacQueen M. Cell proliferation and DNA replication in the imaginal wing disc of Drosophila melanogaster. Dev. Biol. 103 (1984) 28-37
2. Araki M., Yu H., and Asano M. A novel motif governs APC-dependent degradation of Drosophila ORC1 in vivo. Genes Dev. 19 (2005) 2458-2465
3. Badugu R., Yoo Y., Singh P.B., and Kellum R. Mutations in the heterochromatin protein 1 (HP1) hinge domain affect HP1 protein interactions and chromosomal distribution. Chromosoma 113 (2005) 370-384
4. Beall E.L., Bell M., Georlette D., and Botchan M.R. Dm-myb mutant lethality in Drosophila is dependent upon mip130: positive and negative regulation of DNA replication. Genes Dev. 18 (2004) 1667-1680
5. Beall E.L., Manak J.R., Zhou S., Bell M., Lipsick J.S., and Botchan M.R. Role for a Drosophila Myb-containing protein complex in site-specific DNA replication. Nature 420 (2002) 833-837
6. Bessa M., Joaquin M., Tavner F., Saville M.K., and Watson R.J. Regulation of the cell cycle by B-Myb. Blood Cells Mol. Dis. 27 (2001) 416-421
7. Bies J., and Wolff L. Oncogenic activation of c-Myb by carboxyl-terminal truncation leads to decreased proteolysis by the ubiquitin-26S proteasome pathway. Oncogene 14 (1997) 203-212
8. Campos-Ortega J.A., and Hartenstein V. The Embryonic Development of Drosophila melanogaster (1997), Springer, Berlin, New York pp. xvii, 405 p
9. Castro A., Vigneron S., Bernis C., Labbe J.C., and Lorca T. Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway. Mol. Cell Biol. 23 (2003) 4126-4138
10. Catron K.M., Purkerson J.M., Isakson P.C., and Bender T.P. Constitutive versus cell cycle regulation of c-myb mRNA expression correlates with developmental stages in murine B lymphoid tumors. J. Immunol. 148 (1992) 934-942
11. Charrasse S., Carena I., Brondani V., Klempnauer K.H., and Ferrari S. Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCF(p45Skp2) pathway. Oncogene 19 (2000) 2986-2995
12. Dawson I.A., Roth S., Akam M., and Artavanis-Tsakonas S. Mutations of the fizzy locus cause metaphase arrest in Drosophila melanogaster embryos. Development 117 (1993) 359-376
13. Dawson I.A., Roth S., and Artavanis-Tsakonas S. The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J. Cell Biol. 129 (1995) 725-737
14. Duronio R.J., Brook A., Dyson N., and O'Farrell P.H. E2F-induced S phase requires cyclin E. Genes Dev. 10 (1996) 2505-2513
15. Duronio R.J., and O'Farrell P.H. Developmental control of the G1 to S transition in Drosophila: cyclin Eis a limiting downstream target of E2F. Genes Dev. 9 (1995) 1456-1468
16. Ebert A., Schotta G., Lein S., Kubicek S., Krauss V., Jenuwein T., and Reuter G. Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila. Genes Dev. 18 (2004) 2973-2983
17. Edgar B.A., Lehman D.A., and O'Farrell P.H. Transcriptional regulation of string (cdc25): a link between developmental programming and the cell cycle. Development 120 (1994) 3131-3143
18. Edgar B.A., and O'Farrell P.H. The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string. Cell 62 (1990) 469-480
19. Edgar B.A., Sprenger F., Duronio R.J., Leopold P., and O'Farrell P.H. Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis. Genes Dev. 8 (1994) 440-452
20. Fitzpatrick C.A., Sharkov N.V., Ramsay G., and Katzen A.L. Drosophila myb exerts opposing effects on S phase, promoting proliferation and suppressing endoreduplication. Development 129 (2002) 4497-4507
21. Foe V.E. Mitotic domains reveal early commitment of cells in Drosophila embryos. Development 107 (1989) 1-22
22. Fung S.M., Ramsay G., and Katzen A.L. Mutations in Drosophila myb lead to centrosome amplification and genomic instability. Development 129 (2002) 347-359
23. Fung S.M., Ramsay G., and Katzen A.L. MYB and CBP: physiological relevance of a biochemical interaction. Mech. Dev. 120 (2003) 711-720
24. Ganter B., and Lipsick J.S. Myb and oncogenesis. Adv. Cancer Res. 76 (1999) 21-60
25. Glotzer M., Murray A.W., and Kirschner M.W. Cyclin is degraded by the ubiquitin pathway. Nature 349 (1991) 132-138
26. Hiraoka Y., Agard D.A., and Sedat J.W. Temporal and spatial coordination of chromosome movement, spindle formation, and nuclear envelope breakdown during prometaphase in Drosophila melanogaster embryos. J. Cell Biol. 111 (1990) 2815-2828
27. Hirose F., Yamaguchi M., Kuroda K., Omori A., Hachiya T., Ikeda M., Nishimoto Y., and Matsukage A. Isolation and characterization of cDNA for DREF, a promoter-activating factor for Drosophila DNA replication-related genes. J. Biol. Chem. 271 (1996) 3930-3937
28. Huang J., and Raff J.W. The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells. EMBO J. 18 (1999) 2184-2195
29. Huang J.Y., and Raff J.W. The dynamic localisation of the Drosophila APC/C: evidence for the existence of multiple complexes that perform distinct functions and are differentially localised. J. Cell Sci. 115 (2002) 2847-2856
30. Jackson J., Ramsay G., Sharkov N.V., Lium E., and Katzen A.L. The role of transcriptional activation in the function of the Drosophila myb gene. Blood Cells Mol. Dis. 27 (2001) 446-455
31. Jiang J., Kosman D., Ip Y.T., and Levine M. The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos. Genes Dev. 5 (1991) 1881-1891
32. Katzen A.L. Drosophila Myb: lessons for the understanding of vertebrate Myb proteins. Myb Transcription Factors: Their Role in Growth, Differentiation and Disease. Proteins and Cell Regulation vol. 2 (2004), Kluwer Academic Publishers B.V., Dordrecht, The Netherlands 36-64
33. Katzen A.L., and Bishop J.M. Myb provides an essential function during Drosophila development. Proc. Natl. Acad. Sci. USA 93 (1996) 13955-13960
34. Katzen A.L., Jackson J., Harmon B.P., Fung S.M., Ramsay G., and Bishop J.M. Drosophila myb is required for the G2/M transition and maintenance of diploidy. Genes Dev. 12 (1998) 831-843
35. Katzen A.L., Kornberg T.B., and Bishop J.M. Isolation of the proto-oncogene c-myb from D. melanogaster. Cell 41 (1985) 449-456
36. Lam E.W., Bennett J.D., and Watson R.J. Cell-cycle regulation of human B-myb transcription. Gene 160 (1995) 277-281
37. Lam E.W., Robinson C., and Watson R.J. Characterization and cell cycle-regulated expression of mouse B-myb. Oncogene 7 (1992) 1885-1890
38. Lewis P.W., Beall E.L., Fleischer T.C., Georlette D., Link A.J., and Botchan M.R. Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex. Genes Dev. 18 (2004) 2929-2940
39. Lilly M.A., and Spradling A.C. The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion. Genes Dev. 10 (1996) 2514-2526
40. Littlepage L.E., and Ruderman J.V. Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit. Genes Dev. 16 (2002) 2274-2285
41. Lyon J., Robinson C., and Watson R. The role of Myb proteins in normal and neoplastic cell proliferation. Crit. Rev. Oncog. 5 (1994) 373-388
42. Mahowald A.P., and Hardy P.A. Genetics of Drosophila embryogenesis. Annu. Rev. Genet. 19 (1985) 149-177
43. Maldonado-Codina G., and Glover D.M. Cyclins A and B associate with chromatin and the polar regions of spindles, respectively, and do not undergo complete degradation at anaphase in syncytial Drosophila embryos. J. Cell Biol. 116 (1992) 967-976
44. Manak J.R., Mitiku N., and Lipsick J.S. Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability. Proc. Natl. Acad. Sci. USA 99 (2002) 7438-7443
45. Manak J.R., Wen H., Van T., Andrejka L., and Lipsick J.S. Loss of Drosophila Myb interrupts the progression of chromosome condensation. Nat. Cell Biol. 9 (2007) 581-587
46. Margottin-Goguet F., Hsu J.Y., Loktev A., Hsieh H.M., Reimann J.D., and Jackson P.K. Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. Dev. Cell 4 (2003) 813-826
47. Oh I.H., and Reddy E.P. The myb gene family in cell growth, differentiation and apoptosis. Oncogene 18 (1999) 3017-3033
48. Ohno K., Hirose F., Sakaguchi K., Nishida Y., and Matsukage A. Transcriptional regulation of the Drosophila CycA gene by the DNA replication-related element (DRE) and DRE binding factor (DREF). Nucleic Acids Res. 24 (1996) 3942-3946
49. Okada M., Akimaru H., Hou D.X., Takahashi T., and Ishii S. Myb controls G(2)/M progression by inducing cyclin B expression in the Drosophila eye imaginal disc. EMBO J. 21 (2002) 675-684
50. Peters J.M. The anaphase-promoting complex: proteolysis in mitosis and beyond. Mol. Cell. 9 (2002) 931-943
51. Pfleger C.M., and Kirschner M.W. The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes Dev. 14 (2000) 655-665
52. Robinson C., Light Y., Groves R., Mann D., Marias R., and Watson R. Cell-cycle regulation of B-Myb protein expression: specific phosphorylation during the S phase of the cell cycle. Oncogene 12 (1996) 1855-1864
53. Schotta G., Ebert A., Krauss V., Fischer A., Hoffmann J., Rea S., Jenuwein T., Dorn R., and Reuter G. Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. EMBO J. 21 (2002) 1121-1131
54. Schwed G., May N., Pechersky Y., and Calvi B.R. Drosophila minichromosome maintenance 6 is required for chorion gene amplification and genomic replication. Mol. Biol. Cell 13 (2002) 607-620
55. Sharkov N.V., Ramsay G., and Katzen A.L. The DNA replication-related element-binding factor (DREF) is a transcriptional regulator of the Drosophila myb gene. Gene 297 (2002) 209-219
56. Sigrist S., Jacobs H., Stratmann R., and Lehner C.F. Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3. EMBO J. 14 (1995) 4827-4838
57. Stiffler L.A., Ji J.Y., Trautmann S., Trusty C., and Schubiger G. Cyclin A and B functions in the early Drosophila embryo. Development 126 (1999) 5505-5513
58. Su T.T., Campbell S.D., and O'Farrell P.H. Drosophila grapes/CHK1 mutants are defective in cyclin proteolysis and coordination of mitotic events. Curr. Biol. 9 (1999) 919-922
59. Sullivan W., Ashburner M., and Hawley R.S. Drosophila Protocols (2000), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY pp. 140-173
60. Tyler J.K., Bulger M., Kamakaka R.T., Kobayashi R., and Kadonaga J.T. The p55 subunit of Drosophila chromatin assembly factor 1 is homologous to a histone deacetylase-associated protein. Mol. Cell. Biol. 16 (1996) 6149-6159
61. Vlassova I.E., Graphodatsky A.S., Belyaeva E.S., and Zhimulev I.F. Constitutive heterochromatin in early embryogenesis of Drosophila melanogaster. Mol. Gen. Genet. 229 (1991) 316-318
62. Wakefield J.G., Huang J.Y., and Raff J.W. Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos. Curr. Biol. 10 (2000) 1367-1370
63. Whitfield W.G., Gonzalez C., Maldonado-Codina G., and Glover D.M. The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition. EMBO J. 9 (1990) 2563-2572