Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment

DNA Repair

Volumn 7, Issue 6, 2008, Pages 951-969

  Schroering, Allen G ^a   Williams, Kandace J ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Cell cycle synchronization; DNA mismatch repair; Monofunctional alkylation damage

Indexed keywords

CYCLINE; DNA POLYMERASE; METHYLNITRONITROSOGUANIDINE; MISMATCH REPAIR PROTEIN; PROTEIN MUTL; PROTEIN MUTS; TRANSLESION SYNTHESIS POLYMERASE;

ALKYLATION; ARTICLE; CELL CYCLE G2 PHASE; CELL SYNCHRONIZATION; CHROMATIN; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA REPLICATION; DNA SYNTHESIS; DOUBLE STRANDED DNA BREAK; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MISMATCH REPAIR; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

BASE PAIR MISMATCH; BLOTTING, WESTERN; CELL CYCLE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; DNA DAMAGE; DNA REPAIR; FLUORESCENT ANTIBODY TECHNIQUE; HELA CELLS; HUMANS; METHYLNITRONITROSOGUANIDINE;

MAMMALIA;

EID: 43849107802     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2008.03.023     Document Type: Article

References (61)

1. Drablos F., Feyzi E., Aas P.A., Vaagbo C.B., Kavli B., Bratlie M.S., Pena-Diaz J., Otterlei M., Slupphaug G., and Krokan H.E. Alkylation damage in DNA and RNA-repair mechanisms and medical significance. DNA Repair 3 (2004) 1389-1407
2. Sedgwick B., Bates P.A., Paik J., Jacobs S.C., and Lindahl T. Repair of alkylated DNA: recent advances. DNA Repair 6 (2007) 429-442
3. Trivedi R.N., Almeida K.L., Forsaglio J.L., Schamus S., and Sobol R.W. The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death. Cancer Res. 65 (2005) 6394-6400
4. Gerson S.L. MGMT: it's role in cancer aetiology and cancer therapeutics. Nat. Rev. Cancer 4 (2004) 296-307
5. Karran P., and Hampson R. Genomic instability and tolerance to alkylating agents. Cancer Surveys 28 (1996) 69-85
6. Tomita-Mitchell A., Kat A.G., Marcelino L.A., Li-Sucholeiki X.-C., Goodluck-Griffith J., and Thilly W.G. Mismatch repair deficient human cells: spontaneous and MNNG-induced mutational spectra in the HPRT gene. Mutat. Res. 450 (2000) 125-138
7. N1 type methylating agents requires the ATR kinase. Genes Dev. 18 (2004) 1331-1344
8. Tominaga Y., Tsuzuki T., Shiraishi A., Kawate H., and Sekiguchi M. Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting. Carcinogenesis 18 (1997) 889-896
9. Iyer R.R., Pluciennik A., Burdett V., and Modrich P. DNA mismatch repair: functions and mechanisms. Chem. Rev. 106 (2006) 302-323
10. Jiricny J. The multifaceted mismatch-repair system. Nat. Rev. Mol. Cell Biol. 7 (2006) 335-347
11. Hoffman P.D., Wang H., Lawrence C.W., Iwai S., Hanaoka F., and Hays J.B. Binding of MutS mismatch repair protein to DNA containing UV photoproducts, "mismatched" opposite Watson-Crick and novel nucleotides, in different DNA sequence contexts. DNA Repair 4 (2005) 983-993
12. Fourrier L., Brooks P., and Malinge J.-M. Binding discrimination of MutS to a set of lesions and compound lesions (base damage and mismatch) reveals its potential role as a cisplatin-damaged DNA sensing protein. J. Biol. Chem. 278 (2003) 21267-21275
13. Mu D., Tursun M., Duckett D.R., Drummond J.T., Modrich P., and Sancar A. Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems. Mol. Cell. Biol. 17 (1997) 760-769
14. Wu J., Gu L., Wang H., Geacintov N.E., and Li G.M. Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis. Mol. Cell. Biol. 19 (1999) 8292-8301
15. Wu J., Zhu B.-B., Yu J., Zhu H., Qiu L., Kindy M.S., Gu L., Seidel A., and Li G.-M. In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system. Nucleic Acids Res. 31 (2003) 6428-6434
16. Dosch J., Christmann M., and Kaina B. Mismatch G-T binding activity and MSH2 expression is quantitatively related to sensitivity of cells to methylating agents. Carcinogenesis 19 (1998) 567-573
17. 6-methylguanine. Mol. Cell 14 (2004) 105-116
18. Schofield M.J., and Hsieh P. DNA mismatch repair: molecular mechanisms and biological function. Annu. Rev. Microbiol. 57 (2003) 579-608
19. Stojic L., Brun R., and Jiricny J. Mismatch repair and DNA damage signaling. DNA Repair 3 (2004) 1091-1101
20. Yang G., Scherer S.J., Shell S.S., Yang K., Kim M., Lipkin M., Kucherlapati R., Kolodner R.D., and Edelmann W. Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility. Cancer Cell 6 (2004) 139-150
21. Lin D.P., Wang Y., Scherer S.J., Clark A.B., Yang K., Avdievich E., Jin B., Werling U., Parris T., Kurihara N., Umar A., Kucherlapati R., Lipkin M., Kunkel T.A., and Edelmann W. An Msh2 point mutation uncouples DNA mismatch repair and apoptosis. Cancer Res. 64 (2004) 517-522
22. Wang Y., and Qin J. MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 15387-15392
23. 6-methylguanine adducts. Mol. Cell 22 (2006) 501-510
24. 6-methylguanine lesions in human nuclear extracts. J. Biol. Chem. 281 (2006) 22674-22683
25. Hoege C., Pfander B., Moldovan G.-L., Pyrowolakis G., and Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419 (2002) 135-141
26. Kannouche P.L., Wing J., and Lehmann A.R. Interaction of human DNA polymerase η with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. Mol. Cell 14 (2004) 491-500
27. Plosky B.S., and Woodgate R. Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases. Curr. Opin. Genet. Dev. 14 (2004) 113-119
28. Watanabe K., Tateishi S., Kawasuji M., Tsurimoto T., Inoue H., and Yamaizumi M. Rad18 guides pol η to replication stalling sites through physical interaction and PCNA monoubiquitination. EMBO J. 23 (2004) 2004
29. Wood A., Garg P., and Burgers P.M.J. A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage. J. Biol. Chem. 282 (2007) 20256-20263
30. Kitagawa R., Bakkenist C.J., McKinnon P.J., and Kastan M.B. Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes Dev. 18 (2004) 1423-1438
31. Olson E., Nievera C.J., Lee A.Y.-L., Chen L., and Wu X. The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment. J. Biol. Chem. 282 (2007) 22939-22952
32. Schar P., Fasi M., and Jessberger R. SMC1 coordinates DNA double-strand break repair pathways. Nucleic Acids Res. 32 (2004) 3921-3929
33. Zhong H., Bryson A., Eckersdorff M., and Ferguson D.O. Rad50 depletion impacts upon ATR-dependent DNA damage responses. Hum. Mol. Genet. 14 (2005) 2685-2693
34. Christmann M., and Kaina B. Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents. J. Biol. Chem. 275 (2000) 36256-36262
35. 1-S border. Exp. Cell Res. 68 (1971) 163-168
36. Spector D.L., Goldman R.D., and Leinwand L.A. Cells: A Laboratory Manual (1998), Cold Spring Harbor Press
37. Schroering A.G., Edelbrock M.A., Richards T.J., and Williams K.J. The cell cycle and DNA mismatch repair. Exp. Cell Res. 313 (2007) 292-304
38. 6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration. Carcinogenesis 24 (2003) 1337-1345
39. Kaufmann S.H., Desnoyers S., Ottaviano Y., Davidson N.E., and Poirier G. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res. 53 (1993) 3976-3985
40. Rao L., Perez D., and White E. Lamin proteolysis facilitates nuclear events during apoptosis. J. Cell Biol. 135 (1996) 1441-1455
41. Kleczkowska H.E., Marra G., Lettieri T., and Jiricny J. hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci. Genes Dev. 15 (2001) 724-736
42. Jackson D.A., and Pombo A. Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells. J. Cell Biol. 140 (1998) 1285-1295
43. Mi J., and Kupfer G.M. The Fanconi anemia core complex associates with chromatin during S phase. Blood 150 (2005) 759-766
44. Wang X.-Z., Andreassen P.R., and D'Andrea A.D. Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Mol. Cell. Biol. 24 (2004) 5850-5862
45. Jansen J.G., Fousteri M.I., and de Wind N. Send in the clamps: control of DNA translesion synthesis in eukaryotes. Mol. Cell 28 (2007) 522-529
46. Parlanti E., Pascucci B., Terrados G., Blanco L., and Dogliotti E. Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase β-defective mouse cells. DNA Repair 3 (2004) 703-710
47. Friedberg E.C., Walker G.C., Siede W., Wood R.D., Schultz R.A., and Ellenberger T. DNA Repair and Mutagenesis (2006), ASM Press, Washington DC
48. 32P postlabeling: evidence for the nonrandom manifestation of phosphotriester lesions in vivo. Cancer Res. 60 (2000) 1276-1282
49. Ho E.L.Y., Parent M., and Satoh M. Induction of base damages representing a high risk site for double-strand DNA break formation in genomic DNA by exposure of cells to DNA damaging agents. J. Biol. Chem. 282 (2007) 21913-21923
50. Richardson F.C., and Richardson K.K. Sequence-dependent formation of alkyl DNA adducts: a review of methods, results, and biological correlates. Mutat. Res. 233 (1990) 127-138
51. Dery U., and Masson J.-Y. Twists and turns in the function of DNA damage signaling and repair proteins by post-translational modifications. DNA Repair 6 (2007) 561-577
52. Hidaka M., Takagi Y., Takano T.Y., and Sekiguchi M. PCNA-MutSα-mediated binding of MutLα to replicative DNA with mismatched bases to induce apoptosis in human cells. Nucleic Acids Res. 33 (2005) 5703-5712
53. 6-alkylguanine DNA adducts by recombinant human DNA polymerases. J. Biol. Chem. 281 (2006) 38244-38256
54. Spector D.L., Goldman R.D., and Leinwand L.A. Cells: A Laboratory Manual. Cold Spring Harbor Laboratory Press (1998)
55. Warbrick E. The puzzle of PCNA's many partners. Bioessays 22 (2000) 997-1006
56. Masih P.J., Kunnev D., and Melendy T. Mismatch repair proteins are recruited to replicating DNA through interaction with proliferating cell nuclear antigen (PCNA). Nucleic Acids Res. 36 (2008) 67-75
57. Masutani C., Araki M., Yamada A., Kusumoto R., Nogimori T., Maekawa T., Iwai S., and Hanaoka F. Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO J. 18 (1999) 3491-3501
58. Takata K., Shimizu T., Iwai S., and Wood R.D. Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. J. Biol. Chem. 281 (2006) 23445-23455
59. Lomax M.E., Cunniffe S., and O'Neill P. Efficiency of repair of an abasic site within DNA clustered damage sites by mammalian cell nuclear extracts. Biochemistry 43 (2004) 11017-11026
60. Nowosielska A., and Marinus M.G. DNA mismatch repair-induced double-strand breaks. DNA Repair 7 (2008) 48-56
61. 6-methylguanine triggered apoptosis, SCEs and chromosomal aberrations. DNA Repair 3 (2004) 359-368