The 5-HT3B subunit confers spontaneous channel opening and altered ligand properties of the 5-HT3 receptor

Journal of Biological Chemistry

Volumn 283, Issue 11, 2008, Pages 6826-6831

  Hu, Xiang Qun ^a   Peoples, Robert W ^a  

^a MARQUETTE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; HYDRAULIC GATES; MODULATION; MODULATORS;

293 CELLS; ALLOSTERIC MODULATORS; CHANNEL OPENINGS; COUPLED RECEPTORS; G PROTEINS; HUMAN EMBRYONIC KIDNEYS; ION CHANNELS; LIGAND PROPERTIES; POSITIVE ALLOSTERIC MODULATORS; RECEPTOR FUNCTIONS; STATE MODELS; SYNAPTIC TRANSMISSIONS;

LIGANDS;

5 METHOXYINDOLE 2 CARBOXYLIC ACID; LIGAND; RECEPTOR SUBUNIT; SEROTONIN 3A RECEPTOR; SEROTONIN 3B RECEPTOR; 5 METHOXYINDOLE; 5-METHOXYINDOLE; COMPLEMENTARY DNA; INDOLE DERIVATIVE; SEROTONIN 3 RECEPTOR;

ALLOSTERISM; ARTICLE; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR AFFINITY; BIOLOGICAL MODEL; CELL FUNCTION; CELL LINE; CHEMICAL MODEL; CHEMISTRY; GENETIC TRANSFECTION; KINETICS; METABOLISM; PATCH CLAMP; PROTEIN BINDING;

PROTEA;

CELL LINE; CELL PHYSIOLOGY; DNA, COMPLEMENTARY; HUMANS; INDOLES; KINETICS; LIGANDS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; PATCH-CLAMP TECHNIQUES; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, SEROTONIN, 5-HT3; TRANSFECTION;

EID: 43749083736     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M707571200     Document Type: Article

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