Role of gastrointestinal eosinophils in inflammatory bowel disease and intestinal tumours

Best Practice and Research: Clinical Gastroenterology

Volumn 22, Issue 3, 2008, Pages 537-549

  Wedemeyer, Jochen ^a   Vosskuhl, Katja ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

chemokines; colonic neoplasms; Crohn's disease; eosinophils; inflammatory bowel disease; ulcerative colitis

Indexed keywords

ALPHA INTERFERON; AZATHIOPRINE; CHEMOKINE; ENEMA; EOTAXIN; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; INTERLEUKIN 10 ANTIBODY; INTERLEUKIN 5 ANTIBODY; NATALIZUMAB; PLACEBO; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; STEROID; TUMOR NECROSIS FACTOR ALPHA INHIBITOR;

ARTICLE; CARCINOGENESIS; CELL ACTIVATION; CELL DIFFERENTIATION; CELL FUNCTION; CHEMOTAXIS; CLINICAL TRIAL; COLITIS; CROHN DISEASE; DISEASE SEVERITY; EHRLICH ASCITES TUMOR CELL; ENTERITIS; EOSINOPHIL; EOSINOPHILIA; HUMAN; IMMUNOHISTOLOGY; INTESTINE CARCINOMA; INTESTINE TUMOR; NONHUMAN; PATHOGENESIS; ULCERATIVE COLITIS;

CHEMOKINES; EOSINOPHILS; HUMANS; INFLAMMATORY BOWEL DISEASES; INTESTINAL NEOPLASMS;

EID: 43549120052     PISSN: 15216918     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpg.2007.12.001     Document Type: Article

References (70)

1. M.E. Rothenberg S.P. Hogan The eosinophil Annu Rev Immunol 24 2006 147 174
2. H.F. Rosenberg S. Phipps P.S. Foster Eosinophil trafficking in allergy and asthma J Allergy Clin Immunol 119 2007 1303 1310
3. E.A. Jacobsen A.G. Taranova N.A. Lee Eosinophils: singularly destructive effector cells or purveyors of immunoregulation? J Allergy Clin Immunol 119 2007 1313 1320
4. M.F. Neurath Mucosal immunity in Crohn's disease Inflamm Bowel Dis 10 Suppl. 1 2004 S29 S31
5. R.B. Sartor Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis Nat Clin Pract Gastroenterol Hepatol 3 2006 390 407
6. W. Strober I. Fuss P. Mannon The fundamental basis of inflammatory bowel disease J Clin Invest 117 2007 514 521
7. J.P. Hugot CARD15/NOD2 mutations in Crohn's disease Ann N Y Acad Sci 1072 2006 9 18
8. M. Stoll B. Corneliussen C.M. Costello Genetic variation in DLG5 is associated with inflammatory bowel disease Nat Genet 36 2004 476 480
9. S. Waller M. Tremelling F. Bredin Evidence for association of OCTN genes and IBD5 with ulcerative colitis Gut 55 2006 809 814
10. P.D. Collins S. Marleau D.A. Griffiths-Johnson Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo J Exp Med 182 1995 1169 1174
11. P.S. Foster S.P. Hogan A.J. Ramsay Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model J Exp Med 183 1996 195 201
12. A. Mishra S.P. Hogan J.J. Lee Fundamental signals that regulate eosinophil homing to the gastrointestinal tract J Clin Invest 103 1999 1719 1727
13. E.A. Garcia-Zepeda M.E. Rothenberg R.T. Ownbey Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia Nat Med 2 1996 449 456
14. S.P. Hogan A. Mishra E.B. Brandt A pathological function for eotaxin and eosinophils in eosinophilic gastrointestinal inflammation Nat Immunol 2 2001 353 360
15. A.A. Humbles B. Lu D.S. Friend The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness Proc Natl Acad Sci U S A 99 2002 1479 1484
16. S. Danese A. Gasbarrini Chemokines in inflammatory bowel disease J Clin Pathol 58 2005 1025 1027
17. K. Gijsbers K. Geboes J. Van Damme Chemokines in gastrointestinal disorders Curr Drug Targets 7 2006 47 64
18. J. Wedemeyer A. Lorentz M. Goke Enhanced production of monocyte chemotactic protein 3 in inflammatory bowel disease mucosa Gut 44 1999 629 635
19. N. Zimmermann B.L. Daugherty J.L. Kavanaugh Analysis of the CC chemokine receptor 3 gene reveals a complex 5′ exon organization, a functional role for untranslated exon 1, and a broadly active promoter with eosinophil-selective elements Blood 96 2000 2346 2354
20. P.D. Ponath S. Qin T.W. Post Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils J Exp Med 183 1996 2437 2448
21. P.D. Ponath S. Qin D.J. Ringler Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils J Clin Invest 97 1996 604 612
22. H. Tachimoto M. Ebisawa B.S. Bochner Cross-talk between integrins and chemokines that influences eosinophil adhesion and migration Int Arch Allergy Immunol 128 Suppl. 1 2002 18 20
23. S.K. Shaw M.B. Brenner The beta 7 integrins in mucosal homing and retention Semin Immunol 7 1995 335 342
24. H.S. Souza C.C. Elia J. Spencer Expression of lymphocyte-endothelial receptor-ligand pairs, alpha4beta7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease Gut 45 1999 856 863
25. Z.T. Bercovitz S.C. Sommers Altered inflammatory reaction in non-specific ulcerative colitis Arch Intern Med 117 1966 504 510
26. S.C. Bischoff J. Wedemeyer A. Herrmann Quantitative assessment of intestinal eosinophils and mast cells in inflammatory bowel disease Histopathology 28 1996 1 13
27. S.C. Bischoff J. Mayer Q.T. Nguyen Immunnohistological assessment of intestinal eosinophil activation in patients with eosinophilic gastroenteritis and inflammatory bowel disease Am J Gastroenterol 94 1999 3521 3529
28. M.Y. Choy J.A. Walker-Smith C.B. Williams Activated eosinophils in chronic inflammatory bowel disease Lancet 336 1990 126 127
29. S.K. Sarin V. Malhotra G.S. Sen Significance of eosinophil and mast cell counts in rectal mucosa in ulcerative colitis. A prospective controlled study Dig Dis Sci 32 1987 363 367
30. Y. Raab K. Fredens B. Gerdin Eosinophil activation in ulcerative colitis: studies on mucosal release and localization of eosinophil granule constituents Dig Dis Sci 43 1998 1061 1070
31. M. Lampinen A. Ronnblom K. Amin Eosinophil granulocytes are activated during the remission phase of ulcerative colitis Gut 54 2005 1714 1720
32. A.T. Carvalho C.C. Elia H.S. de Souza Immunohistochemical study of intestinal eosinophils in inflammatory bowel disease J Clin Gastroenterol 36 2003 120 125
33. M. Jeziorska N. Haboubi P. Schofield Distribution and activation of eosinophils in inflammatory bowel disease using an improved immunohistochemical technique J Pathol 194 2001 484 492
34. W.J. Beil A.R. McEuen M. Schulz Selective alterations in mast cell subsets and eosinophil infiltration in two complementary types of intestinal inflammation: ascariasis and Crohn's disease Pathobiology 70 2002 303 313
35. S. Dubucquoi A. Janin O. Klein Activated eosinophils and interleukin 5 expression in early recurrence of Crohn's disease Gut 37 1995 242 246
36. A.M. Dvorak Ultrastructural evidence for release of major basic protein-containing crystalline cores of eosinophil granules in vivo: cytotoxic potential in Crohn's disease J Immunol 125 1980 460 462
37. W. Luck M. Becker B. Niggemann In vitro release of eosinophil cationic protein from peripheral eosinophils reflects disease activity in childhood Crohn disease and ulcerative colitis Eur J Pediatr 156 1997 921 924
38. L.C. Coppi S.M. Thomazzi M.L. de Ayrizono Comparative study of eosinophil chemotaxis, adhesion, and degranulation in vitro in ulcerative colitis and Crohn's disease Inflamm Bowel Dis 13 2007 211 218
39. A. Mir M. Minguez J. Tatay Elevated serum eotaxin levels in patients with inflammatory bowel disease Am J Gastroenterol 97 2002 1452 1457
40. W. Chen B. Paulus D. Shu Increased serum levels of eotaxin in patients with inflammatory bowel disease Scand J Gastroenterol 36 2001 515 520
41. A. Berstad B. Borkje B. Riedel Increased fecal eosinophil cationic protein in inflammatory bowel disease Hepatogastroenterology 40 1993 276 278
42. S.C. Bischoff J. Grabowsky M.P. Manns Quantification of inflammatory mediators in stool samples of patients with inflammatory bowel disorders and controls Dig Dis Sci 42 1997 394 403
43. O. Saitoh K. Kojima K. Sugi Fecal eosinophil granule-derived proteins reflect disease activity in inflammatory bowel disease Am J Gastroenterol 94 1999 3513 3520
44. C.G. Peterson E. Eklund Y. Taha A new method for the quantification of neutrophil and eosinophil cationic proteins in feces: establishment of normal levels and clinical application in patients with inflammatory bowel disease Am J Gastroenterol 97 2002 1755 1762
45. A.M. Levy G.J. Gleich W.J. Sandborn Increased eosinophil granule proteins in gut lavage fluid from patients with inflammatory bowel disease Mayo Clin Proc 72 1997 117 123
46. S. Winterkamp M. Raithel E.G. Hahn Secretion and tissue content of eosinophil cationic protein in Crohn's disease J Clin Gastroenterol 30 2000 170 175
47. M. Carlson Y. Raab C. Peterson Increased intraluminal release of eosinophil granule proteins EPO, ECP, EPX, and cytokines in ulcerative colitis and proctitis in segmental perfusion Am J Gastroenterol 94 1999 1876 1883
48. E. Forbes T. Murase M. Yang Immunopathogenesis of experimental ulcerative colitis is mediated by eosinophil peroxidase J Immunol 172 2004 5664 5675
49. G.T. Furuta E.E. Nieuwenhuis J. Karhausen Eosinophils alter colonic epithelial barrier function: role for major basic protein Am J Physiol Gastrointest Liver Physiol 289 2005 G890 G897
50. J.J. Lee D. Dimina M.P. Macias Defining a link with asthma in mice congenitally deficient in eosinophils Science 305 2004 1773 1776
51. C. Yu A.B. Cantor H. Yang Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo J Exp Med 195 2002 1387 1395
52. D.C. Baumgart W.J. Sandborn Inflammatory bowel disease: clinical aspects and established and evolving therapies Lancet 369 2007 1641 1657
53. R.P. Schleimer B.S. Bochner The effects of glucocorticoids on human eosinophils J Allergy Clin Immunol 94 1994 1202 1213
54. P. Sangfelt M. Carlson M. Thorn Neutrophil and eosinophil granule proteins as markers of response to local prednisolone treatment in distal ulcerative colitis and proctitis Am J Gastroenterol 96 2001 1085 1090
55. D.C. Baumgart A.U. Dignass Current biological therapies for inflammatory bowel disease Curr Pharm Des 10 2004 4127 4147
56. M. Lampinen M. Carlson P. Sangfelt IL-5 and TNF-alpha participate in recruitment of eosinophils to intestinal mucosa in ulcerative colitis Dig Dis Sci 46 2001 2004 2009
57. P. Rutgeerts W.J. Sandborn B.G. Feagan Infliximab for induction and maintenance therapy for ulcerative colitis N Engl J Med 353 2005 2462 2476
58. W.J. Sandborn J.F. Colombel R. Enns Natalizumab induction and maintenance therapy for Crohn's disease N Engl J Med 353 2005 1912 1925
59. E.B. Brandt N. Zimmermann E.E. Muntel The alpha4bbeta7-integrin is dynamically expressed on murine eosinophils and involved in eosinophil trafficking to the intestine Clin Exp Allergy 36 2006 543 553
60. J.R. Korzenik B.K. Dieckgraefe J.F. Valentine Sargramostim for active Crohn's disease N Engl J Med 352 2005 2193 2201
61. D. Aldebert B. Lamkhioued C. Desaint Eosinophils express a functional receptor for interferon alpha: inhibitory role of interferon alpha on the release of mediators Blood 87 1996 2354 2360
62. R.W. Summers D.E. Elliott J.F. Urban Jr. Trichuris suis therapy in Crohn's disease Gut 54 2005 87 90
63. R.L. Kradin K. Badizadegan P. Auluck Iatrogenic Trichuris suis infection in a patient with Crohn disease Arch Pathol Lab Med 130 2006 718 720
64. E. Przewoski Über die lokale Eosinophilie beim Krebs nebst Bemerkungen über die Bedeutung der eosinophilen Zellen im Allgemeinen Zentralbl f allg Path u path Anat 7 1896 177
65. I.L. Yoon The eosinophil and gastrointestinal carcinoma Am J Surg 97 1959 195 200
66. T.P. Pretlow E.F. Keith A.K. Cryar Eosinophil infiltration of human colonic carcinomas as a prognostic indicator Cancer Res 43 1983 2997 3000
67. M.J. Fernandez-Acenero M. Galindo-Gallego J. Sanz Prognostic influence of tumor-associated eosinophilic infiltrate in colorectal carcinoma Cancer 88 2000 1544 1548
68. L. Simson J.I. Ellyard L.A. Dent Regulation of carcinogenesis by IL-5 and CCL11: a potential role for eosinophils in tumor immune surveillance J Immunol 178 2007 4222 4229
69. E.R. Fisher S.M. Paik H. Rockette Prognostic significance of eosinophils and mast cells in rectal cancer: findings from the National Surgical Adjuvant Breast and Bowel Project (protocol R-01) Hum Pathol 20 1989 159 163
70. J. Moezzi N. Gopalswamy R.J. Haas Jr. Stromal eosinophilia in colonic epithelial neoplasms Am J Gastroenterol 95 2000 520 523