-
1
-
-
0030843626
-
Juvenile myelomonocytic leukemia
-
Aricò, M., Biondi, A. Pui, C.H. (1997) Juvenile myelomonocytic leukemia. Blood, 90, 479 488.
-
(1997)
Blood
, vol.90
, pp. 479-488
-
-
Aricò, M.1
Biondi, A.2
Pui, C.H.3
-
2
-
-
0030712155
-
Occurrence of myeloproliferative disorder in patients with Noonan syndrome
-
Bader-Meunier, B., Tchernia, G., Miélot, F., Fontaine, J.L., Thomas, C., Lyonnet, S., Lavergne, J.M. Dommergues, J.P. (1997) Occurrence of myeloproliferative disorder in patients with Noonan syndrome. Journal of Pediatrics, 130, 885 889.
-
(1997)
Journal of Pediatrics
, vol.130
, pp. 885-889
-
-
Bader-Meunier, B.1
Tchernia, G.2
Miélot, F.3
Fontaine, J.L.4
Thomas, C.5
Lyonnet, S.6
Lavergne, J.M.7
Dommergues, J.P.8
-
3
-
-
35148867031
-
Non-hematopoietic stem cell transplantation treatment of juvenile myelomonocytic leukemia: A retrospective analysis and definition of response criteria
-
Bergstraesser, E., Hasle, H., Rogge, T., Fischer, A., Zimmermann, M., Noellke, P. Niemeyer, C.M. (2007) Non-hematopoietic stem cell transplantation treatment of juvenile myelomonocytic leukemia: a retrospective analysis and definition of response criteria. Pediatric Blood & Cancer, 49, 629 633.
-
(2007)
Pediatric Blood & Cancer
, vol.49
, pp. 629-633
-
-
Bergstraesser, E.1
Hasle, H.2
Rogge, T.3
Fischer, A.4
Zimmermann, M.5
Noellke, P.6
Niemeyer, C.M.7
-
4
-
-
0036529829
-
Transient hematologic and clinical effect of E21R in a child with end-stage juvenile myelomonocytic leukemia
-
Bernard, F., Thomas, C., Emile, J.F., Hercus, T., Cassinat, B., Chomienne, C. Donadieu, J. (2002) Transient hematologic and clinical effect of E21R in a child with end-stage juvenile myelomonocytic leukemia. Blood, 99, 2615 2616.
-
(2002)
Blood
, vol.99
, pp. 2615-2616
-
-
Bernard, F.1
Thomas, C.2
Emile, J.F.3
Hercus, T.4
Cassinat, B.5
Chomienne, C.6
Donadieu, J.7
-
5
-
-
0345743699
-
Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder
-
Braun, B.S., Tuveson, D.A., Kong, N., Le, D.T., Kogan, S.C., Rozmus, J., Le Beau, M.M., Jacks, T.E. Shannon, K.M. (2004) Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder. Proceedings of The National Academy of Sciences of the USA, 101, 597 602.
-
(2004)
Proceedings of the National Academy of Sciences of the USA
, vol.101
, pp. 597-602
-
-
Braun, B.S.1
Tuveson, D.A.2
Kong, N.3
Le, D.T.4
Kogan, S.C.5
Rozmus, J.6
Le Beau, M.M.7
Jacks, T.E.8
Shannon, K.M.9
-
6
-
-
0028831774
-
Clonality in juvenile chronic myelogenious leukemia
-
Busque, L., Gilliland, D.G., Prchal, J.T., Sieff, C.A., Weinstein, H.J., Sokol, J.M., Belickova, M., Wayne, A.S., Zuckerman, K.S., Sokol, L. Castleberry, R.P. (1995) Clonality in juvenile chronic myelogenious leukemia. Blood, 85, 21 30.
-
(1995)
Blood
, vol.85
, pp. 21-30
-
-
Busque, L.1
Gilliland, D.G.2
Prchal, J.T.3
Sieff, C.A.4
Weinstein, H.J.5
Sokol, J.M.6
Belickova, M.7
Wayne, A.S.8
Zuckerman, K.S.9
Sokol, L.10
Castleberry, R.P.11
-
7
-
-
33947305184
-
Phase II Window Study of the Farnesyltransferase Inhibitor R115777 (Zarnestra) in Untreated Juvenile Myelomonocytic Leukemia (JMML): A Children's Oncology Group Study
-
Castleberry, R.P., Loh, M.L., Jayaprakash, N., Peterson, A., Casey, V., Chang, M., Widemann, B. Emanuel, P.D. (2005) Phase II Window Study of the Farnesyltransferase Inhibitor R115777 (Zarnestra) in Untreated Juvenile Myelomonocytic Leukemia (JMML): A Children's Oncology Group Study. Blood (ASH Meeting Abstracts), 106, 727a.
-
(2005)
Blood (ASH Meeting Abstracts)
, vol.106
-
-
Castleberry, R.P.1
Loh, M.L.2
Jayaprakash, N.3
Peterson, A.4
Casey, V.5
Chang, M.6
Widemann, B.7
Emanuel, P.D.8
-
8
-
-
33846854905
-
PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase
-
Chan, R.J. Feng, G.S. (2007) PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase. Blood, 109, 862 867.
-
(2007)
Blood
, vol.109
, pp. 862-867
-
-
Chan, R.J.1
Feng, G.S.2
-
9
-
-
18244395853
-
Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor
-
Chan, R.J., Leedy, M.B., Munugalavadla, V., Voorhorst, C.S., Li, Y., Yu, M. Kapur, R. (2005) Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor. Blood, 105, 3737 3742.
-
(2005)
Blood
, vol.105
, pp. 3737-3742
-
-
Chan, R.J.1
Leedy, M.B.2
Munugalavadla, V.3
Voorhorst, C.S.4
Li, Y.5
Yu, M.6
Kapur, R.7
-
10
-
-
33646589708
-
Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies
-
Chen, Y., Takita, J., Hiwatari, M., Igarashi, T., Hanada, R., Kikuchi, A., Hongo, T., Taki, T., Ogasawara, M., Shimada, A. Hayashi, Y. (2006) Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies. Genes, Chromosomes and Cancer, 45, 583 591.
-
(2006)
Genes, Chromosomes and Cancer
, vol.45
, pp. 583-591
-
-
Chen, Y.1
Takita, J.2
Hiwatari, M.3
Igarashi, T.4
Hanada, R.5
Kikuchi, A.6
Hongo, T.7
Taki, T.8
Ogasawara, M.9
Shimada, A.10
Hayashi, Y.11
-
11
-
-
0034665775
-
Evidence that juvenile myelomonocytic leukemia can arise from a pluripotential stem cell
-
Cooper, L.J., Shannon, K.M., Loken, M.R., Weaver, M., Stephens, K. Sievers, E.L. (2000) Evidence that juvenile myelomonocytic leukemia can arise from a pluripotential stem cell. Blood, 96, 2310 2313.
-
(2000)
Blood
, vol.96
, pp. 2310-2313
-
-
Cooper, L.J.1
Shannon, K.M.2
Loken, M.R.3
Weaver, M.4
Stephens, K.5
Sievers, E.L.6
-
12
-
-
0034651043
-
Inhibition of juvenile myelomonocytic leukemia cell growth in vitro by farnesyltransferase inhibitors
-
Emanuel, P.D., Snyder, R.C., Wiley, T., Gopurala, B. Castleberry, R.P. (2000) Inhibition of juvenile myelomonocytic leukemia cell growth in vitro by farnesyltransferase inhibitors. Blood, 95, 639 645.
-
(2000)
Blood
, vol.95
, pp. 639-645
-
-
Emanuel, P.D.1
Snyder, R.C.2
Wiley, T.3
Gopurala, B.4
Castleberry, R.P.5
-
13
-
-
0032896457
-
RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML)
-
Flotho, C., Valcamonica, S., Mach-Pascual, S., Schmahl, G., Corral, L., Ritterbach, J., Hasle, H., Aricò, M., Biondi, A. Niemeyer, C.M. (1999) RAS mutations and clonality analysis in children with juvenile myelomonocytic leukemia (JMML). Leukemia, 13, 32 37.
-
(1999)
Leukemia
, vol.13
, pp. 32-37
-
-
Flotho, C.1
Valcamonica, S.2
MacH-Pascual, S.3
Schmahl, G.4
Corral, L.5
Ritterbach, J.6
Hasle, H.7
Aricò, M.8
Biondi, A.9
Niemeyer, C.M.10
-
14
-
-
38349111411
-
Genotype-phenotype correlation in cases of juvenile myelomonocytic leukemia with clonal RAS mutations
-
on behalf of the European Working Group of Myelodysplastic Syndromes in Childhood (
-
Flotho, C., Kratz, C.P., Bergsträsser, E., Hasle, H., Stary, J., Trebo, M., van den Heuvel-Eibrink, M.M., Wójcik, D., Zecca, M., Locatelli, F. Niemeyer, C.M. on behalf of the European Working Group of Myelodysplastic Syndromes in Childhood (2007) Genotype-phenotype correlation in cases of juvenile myelomonocytic leukemia with clonal RAS mutations. Blood, 111, 966 967.
-
(2007)
Blood
, vol.111
, pp. 966-967
-
-
Flotho, C.1
Kratz, C.P.2
Bergsträsser, E.3
Hasle, H.4
Stary, J.5
Trebo, M.6
Van Den Heuvel-Eibrink, M.M.7
Wójcik, D.8
Zecca, M.9
Locatelli, F.10
Niemeyer, C.M.11
-
15
-
-
20244362034
-
European Working Group on childhood MDS. the International Prognostic Scoring System (IPSS) for childhood myelodysplastic syndrome (MDS) and juvenile myelomonocytic leukemia (JMML)
-
Hasle, H., Baumann, I., Bergsträsser, E., Fenu, S., Fischer, A., Kardos, G., Kerndrup, G., Locatelli, F., Rogge, T., Schultz, K.R., Stary, J., Trebo, M., van den Heuvel-Eibrink, M.M., Harbott, J., Nöllke, P. Niemeyer, C.M. (2004) European Working Group on childhood MDS. The International Prognostic Scoring System (IPSS) for childhood myelodysplastic syndrome (MDS) and juvenile myelomonocytic leukemia (JMML). Leukemia, 18, 2008 2014.
-
(2004)
Leukemia
, vol.18
, pp. 2008-2014
-
-
Hasle, H.1
Baumann, I.2
Bergsträsser, E.3
Fenu, S.4
Fischer, A.5
Kardos, G.6
Kerndrup, G.7
Locatelli, F.8
Rogge, T.9
Schultz, K.R.10
Stary, J.11
Trebo, M.12
Van Den Heuvel-Eibrink, M.M.13
Harbott, J.14
Nöllke, P.15
Niemeyer, C.M.16
-
16
-
-
33749324960
-
Identification of an immunogenic CD8+ T-cell epitope derived from gamma-globin, a putative tumor-associated antigen for juvenile myelomonocytic leukemia
-
Hirano, N., Butler, M.O., Xia, Z., Berezovskaya, A., Murray, A.P., Ansén, S., Kojima, S. Nadler, L.M. (2006) Identification of an immunogenic CD8+ T-cell epitope derived from gamma-globin, a putative tumor-associated antigen for juvenile myelomonocytic leukemia. Blood, 108, 2662 2668.
-
(2006)
Blood
, vol.108
, pp. 2662-2668
-
-
Hirano, N.1
Butler, M.O.2
Xia, Z.3
Berezovskaya, A.4
Murray, A.P.5
Ansén, S.6
Kojima, S.7
Nadler, L.M.8
-
17
-
-
0029796382
-
Inhibition of proliferation and induction of apoptosis in juvenile myelomonocytic leukemic cells by the granulocyte-macrophage colony-stimulating factor analogue E21R
-
Iversen, P.O., Rodwell, R.L., Pitcher, L., Taylor, K.M. Lopez, A.F. (1996) Inhibition of proliferation and induction of apoptosis in juvenile myelomonocytic leukemic cells by the granulocyte-macrophage colony-stimulating factor analogue E21R. Blood, 88, 2634 2639.
-
(1996)
Blood
, vol.88
, pp. 2634-2639
-
-
Iversen, P.O.1
Rodwell, R.L.2
Pitcher, L.3
Taylor, K.M.4
Lopez, A.F.5
-
18
-
-
0031470405
-
Inhibition of granulocyte-macrophage colony-stimulating factor prevents dissemination and induces remission of juvenile myelomonocytic leukemia in engrafted immunodeficient mice
-
Iversen, P.O., Lewis, I.D., Turczynowicz, S., Hasle, H., Niemeyer, C., Schmiegelow, K., Bastiras, S., Biondi, A., Hughes, T.P. Lopez, A.F. (1997) Inhibition of granulocyte-macrophage colony-stimulating factor prevents dissemination and induces remission of juvenile myelomonocytic leukemia in engrafted immunodeficient mice. Blood, 90, 4910 4917.
-
(1997)
Blood
, vol.90
, pp. 4910-4917
-
-
Iversen, P.O.1
Lewis, I.D.2
Turczynowicz, S.3
Hasle, H.4
Niemeyer, C.5
Schmiegelow, K.6
Bastiras, S.7
Biondi, A.8
Hughes, T.P.9
Lopez, A.F.10
-
19
-
-
0036624790
-
Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth
-
Iversen, P.O., Emanuel, P.D. Sioud, M. (2002) Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth. Blood, 99, 4147 4153.
-
(2002)
Blood
, vol.99
, pp. 4147-4153
-
-
Iversen, P.O.1
Emanuel, P.D.2
Sioud, M.3
-
20
-
-
36048994587
-
Concomitant EBV-related B-cell proliferation and juvenile myelomonocytic leukemia in a 2-year-old child
-
Janik-Moszant, A., Barc-Czarnecka, M., van der Burg, M., Langerak, A.W., Hartwig, N.G., Vossen, A.C., Niemeyer, C.M., Wachowiak, J., Sonta-Jakimczyk, D. Szczepanski, T. (2008) Concomitant EBV-related B-cell proliferation and juvenile myelomonocytic leukemia in a 2-year-old child. Leukemia Research, 32, 181 184.
-
(2008)
Leukemia Research
, vol.32
, pp. 181-184
-
-
Janik-Moszant, A.1
Barc-Czarnecka, M.2
Van Der Burg, M.3
Langerak, A.W.4
Hartwig, N.G.5
Vossen, A.C.6
Niemeyer, C.M.7
Wachowiak, J.8
Sonta-Jakimczyk, D.9
Szczepanski, T.10
-
21
-
-
0028125213
-
Genetic analysis is consistent with the hypothesis that NF1 limits myeloid cell growth through p21ras
-
Kalra, R., Paderanga, D.C., Olson, K. Shannon, K.M. (1994) Genetic analysis is consistent with the hypothesis that NF1 limits myeloid cell growth through p21ras. Blood, 84, 3435 3439.
-
(1994)
Blood
, vol.84
, pp. 3435-3439
-
-
Kalra, R.1
Paderanga, D.C.2
Olson, K.3
Shannon, K.M.4
-
22
-
-
15544380331
-
Allogeneic bone marrow transplantation for juvenile myelomonocytic leukemia: A single center experience of 23 patients
-
Korthof, E.T., Snijder, P.P., de Graaff, A.A., Lankester, A.C., Bredius, R.G., Ball, L.M., Lie, J.L., Vossen, J.M. Egeler, R.M. (2005) Allogeneic bone marrow transplantation for juvenile myelomonocytic leukemia: a single center experience of 23 patients. Bone Marrow Transplantation, 35, 455 461.
-
(2005)
Bone Marrow Transplantation
, vol.35
, pp. 455-461
-
-
Korthof, E.T.1
Snijder, P.P.2
De Graaff, A.A.3
Lankester, A.C.4
Bredius, R.G.5
Ball, L.M.6
Lie, J.L.7
Vossen, J.M.8
Egeler, R.M.9
-
23
-
-
24744455046
-
The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease
-
Kratz, C.P., Niemeyer, C.M., Castleberry, R.P., Cetin, M., Bergsträsser, E., Emanuel, P.D., Hasle, H., Kardos, G., Klein, C., Kojima, S., Stary, J., Trebo, M., Zecca, M., Gelb, B.D., Tartaglia, M. Loh, M.L. (2005) The mutational spectrum of PTPN11 in juvenile myelomonocytic leukemia and Noonan syndrome/myeloproliferative disease. Blood, 106, 2183 2185.
-
(2005)
Blood
, vol.106
, pp. 2183-2185
-
-
Kratz, C.P.1
Niemeyer, C.M.2
Castleberry, R.P.3
Cetin, M.4
Bergsträsser, E.5
Emanuel, P.D.6
Hasle, H.7
Kardos, G.8
Klein, C.9
Kojima, S.10
Stary, J.11
Trebo, M.12
Zecca, M.13
Gelb, B.D.14
Tartaglia, M.15
Loh, M.L.16
-
24
-
-
0028358155
-
Lymphoid blast crisis of B-lineage phenotype with monosomy 7 in a patient with juvenile chronic myelogenous leukemia (JCML)
-
Lau, R.C., Squire, J., Brisson, L., Kamel-Reid, S., Grunberger, T., Dubé, I., Letarte, M., Shannon, K. Freedman, M.H. (1994) Lymphoid blast crisis of B-lineage phenotype with monosomy 7 in a patient with juvenile chronic myelogenous leukemia (JCML). Leukemia, 8, 903 908.
-
(1994)
Leukemia
, vol.8
, pp. 903-908
-
-
Lau, R.C.1
Squire, J.2
Brisson, L.3
Kamel-Reid, S.4
Grunberger, T.5
Dubé, I.6
Letarte, M.7
Shannon, K.8
Freedman, M.H.9
-
25
-
-
2542457470
-
Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder
-
Le, D.T., Kong, N., Zhu, Y., Lauchle, J.O., Aiyigari, A., Braun, B.S., Wang, E., Kogan, S.C., Le Beau, M.M., Parada, L. Shannon, K.M. (2004) Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder. Blood, 103, 4243 4250.
-
(2004)
Blood
, vol.103
, pp. 4243-4250
-
-
Le, D.T.1
Kong, N.2
Zhu, Y.3
Lauchle, J.O.4
Aiyigari, A.5
Braun, B.S.6
Wang, E.7
Kogan, S.C.8
Le Beau, M.M.9
Parada, L.10
Shannon, K.M.11
-
26
-
-
19944428598
-
Hematopoietic stem cell transplantation (HSCT) in children with juvenile myelomonocytic leukemia (JMML): Results of the EWOG-MDS/EBMT trial
-
European Working Group on Childhood MDS; European Blood and Marrow Transplantation Group (
-
Locatelli, F., Nollke, P., Zecca, M., Korthof, E., Lanino, E., Peters, C., Pession, A., Kabisch, H., Uderzo, C., Bonfim, C.S., Bader, P., Dilloo, D., Stary, J., Fischer, A., Revesz, T., Fuhrer, M., Hasle, H., Trebo, M., van den Heuvel-Eibrink, M.M., Fenu, S., Strahm, B., Giorgiani, G., Bonora, M.R., Duffner, U. Niemeyer, C.M. European Working Group on Childhood MDS; European Blood and Marrow Transplantation Group (2005) Hematopoietic stem cell transplantation (HSCT) in children with juvenile myelomonocytic leukemia (JMML): results of the EWOG-MDS/EBMT trial. Blood, 105, 410 419.
-
(2005)
Blood
, vol.105
, pp. 410-419
-
-
Locatelli, F.1
Nollke, P.2
Zecca, M.3
Korthof, E.4
Lanino, E.5
Peters, C.6
Pession, A.7
Kabisch, H.8
Uderzo, C.9
Bonfim, C.S.10
Bader, P.11
Dilloo, D.12
Stary, J.13
Fischer, A.14
Revesz, T.15
Fuhrer, M.16
Hasle, H.17
Trebo, M.18
Van Den Heuvel-Eibrink, M.M.19
Fenu, S.20
Strahm, B.21
Giorgiani, G.22
Bonora, M.R.23
Duffner, U.24
Niemeyer, C.M.25
more..
-
27
-
-
0036173565
-
Human herpesvirus 6 infection mimicking juvenile myelomonocytic leukemia in an infant
-
Lorenzana, A., Lyons, H., Sawaf, H., Higgins, M., Carrigan, D. Emanuel, P.D. (2002) Human herpesvirus 6 infection mimicking juvenile myelomonocytic leukemia in an infant. Journal of Pediatric Hematology and Oncology, 24, 136 141.
-
(2002)
Journal of Pediatric Hematology and Oncology
, vol.24
, pp. 136-141
-
-
Lorenzana, A.1
Lyons, H.2
Sawaf, H.3
Higgins, M.4
Carrigan, D.5
Emanuel, P.D.6
-
28
-
-
0033555976
-
Myelodysplastic and myeloproliferative disorders of childhood: A study of 167 patients
-
Luna-Fineman, S., Shannon, K.M., Atwater, S.K., Davis, J., Masterson, M., Ortega, J., Sanders, J., Steinherz, P., Weinberg, V. Lange, B.J. (1999) Myelodysplastic and myeloproliferative disorders of childhood: a study of 167 patients. Blood, 93, 459 466.
-
(1999)
Blood
, vol.93
, pp. 459-466
-
-
Luna-Fineman, S.1
Shannon, K.M.2
Atwater, S.K.3
Davis, J.4
Masterson, M.5
Ortega, J.6
Sanders, J.7
Steinherz, P.8
Weinberg, V.9
Lange, B.J.10
-
29
-
-
0033214846
-
In vitro and in vivo effects of a farnesyltransferase inhibitor on Nf1-deficient hematopoietic cells
-
Mahgoub, N., Taylor, B.R., Gratiot, M., Kohl, N.E., Gibbs, J.B., Jacks, T. Shannon, K.M. (1999) In vitro and in vivo effects of a farnesyltransferase inhibitor on Nf1-deficient hematopoietic cells. Blood, 94, 2469 2476.
-
(1999)
Blood
, vol.94
, pp. 2469-2476
-
-
Mahgoub, N.1
Taylor, B.R.2
Gratiot, M.3
Kohl, N.E.4
Gibbs, J.B.5
Jacks, T.6
Shannon, K.M.7
-
30
-
-
85014195924
-
Allogeneic hematopoietic stem cell transplantation for 27 children with juvenile myelomonocytic leukemia diagnosed based on the criteria of the International JMML Working Group
-
MDS Committee of the Japanese Society of Pediatric Hematology (
-
Manabe, A., Okamura, J., Yumura-Yagi, K., Akiyama, Y., Sako, M., Uchiyama, H., Kojima, S., Koike, K., Saito, T. Nakahata, T. MDS Committee of the Japanese Society of Pediatric Hematology (2002) Allogeneic hematopoietic stem cell transplantation for 27 children with juvenile myelomonocytic leukemia diagnosed based on the criteria of the International JMML Working Group. Leukemia, 16, 645 649.
-
(2002)
Leukemia
, vol.16
, pp. 645-649
-
-
Manabe, A.1
Okamura, J.2
Yumura-Yagi, K.3
Akiyama, Y.4
Sako, M.5
Uchiyama, H.6
Kojima, S.7
Koike, K.8
Saito, T.9
Nakahata, T.10
-
31
-
-
33644502897
-
Chromosomal change during 6-mercaptopurine (6-MP) therapy in juvenile myelomonocytic leukemia: The growth of a 6-MP-refractory clone that already exists at onset
-
Matsuda, K., Matsuzaki, S., Miki, J., Hidaka, E., Yanagisawa, R., Nakazawa, Y., Sakashit, K., Kamijo, T., Asami, K., Sano, K. Koike, K. (2006) Chromosomal change during 6-mercaptopurine (6-MP) therapy in juvenile myelomonocytic leukemia: the growth of a 6-MP-refractory clone that already exists at onset. Leukemia, 20, 485 490.
-
(2006)
Leukemia
, vol.20
, pp. 485-490
-
-
Matsuda, K.1
Matsuzaki, S.2
Miki, J.3
Hidaka, E.4
Yanagisawa, R.5
Nakazawa, Y.6
Sakashit, K.7
Kamijo, T.8
Asami, K.9
Sano, K.10
Koike, K.11
-
32
-
-
36349016067
-
Acquirement of loss of the wild-type NRAS locus with aggressive disease progression in a patient with juvenile myelomonocytic leukemia and a heterozygous NRAS mutation
-
Matsuda, K., Nakazawa, Y., Sakashita, K., Shiohara, M., Yamauchi, K. Koike, K. (2007a) Acquirement of loss of the wild-type NRAS locus with aggressive disease progression in a patient with juvenile myelomonocytic leukemia and a heterozygous NRAS mutation. Haematologica, 92, 1576 1578.
-
(2007)
Haematologica
, vol.92
, pp. 1576-1578
-
-
Matsuda, K.1
Nakazawa, Y.2
Sakashita, K.3
Shiohara, M.4
Yamauchi, K.5
Koike, K.6
-
33
-
-
34250017142
-
Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations
-
Matsuda, K., Shimada, A., Yoshida, N., Ogawa, A., Watanabe, A., Yajima, S., Iizuka, S., Koike, K., Yanai, F., Kawasaki, K., Yanagimachi, M., Kikuchi, A., Ohtsuka, Y., Hidaka, E., Yamauchi, K., Tanaka, M., Yanagisawa, R., Nakazawa, Y., Shiohara, M., Manabe, A., Kojima, S. Koike, K. (2007b) Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. Blood, 109, 5477 5480.
-
(2007)
Blood
, vol.109
, pp. 5477-5480
-
-
Matsuda, K.1
Shimada, A.2
Yoshida, N.3
Ogawa, A.4
Watanabe, A.5
Yajima, S.6
Iizuka, S.7
Koike, K.8
Yanai, F.9
Kawasaki, K.10
Yanagimachi, M.11
Kikuchi, A.12
Ohtsuka, Y.13
Hidaka, E.14
Yamauchi, K.15
Tanaka, M.16
Yanagisawa, R.17
Nakazawa, Y.18
Shiohara, M.19
Manabe, A.20
Kojima, S.21
Koike, K.22
more..
-
34
-
-
22144454674
-
Development of two cytogenetically abnormal clones from multipotential hematopoietic stem cells in a patient with juvenile myelomonocytic leukemia
-
Matsuzaki, S., Matsuda, K., Miki, J., Nakazawa, Y., Sakashita, K., Kamijo, T., Hidaka, E. Koike, K. (2005) Development of two cytogenetically abnormal clones from multipotential hematopoietic stem cells in a patient with juvenile myelomonocytic leukemia. Leukemia Research, 29, 1069 1072.
-
(2005)
Leukemia Research
, vol.29
, pp. 1069-1072
-
-
Matsuzaki, S.1
Matsuda, K.2
Miki, J.3
Nakazawa, Y.4
Sakashita, K.5
Kamijo, T.6
Hidaka, E.7
Koike, K.8
-
35
-
-
0034081412
-
Exhaustive mutation analysis of the NF1 gene allows identification of 95% of mutations and reveals a high frequency of unusual splicing defects
-
Messiaen, L.M., Callens, T., Mortier, G., Beysen, D., Vandenbroucke, I., Van Roy, N., Speleman, F. Paepe, A.D. (2000) Exhaustive mutation analysis of the NF1 gene allows identification of 95% of mutations and reveals a high frequency of unusual splicing defects. Human Mutation, 15, 541 555.
-
(2000)
Human Mutation
, vol.15
, pp. 541-555
-
-
Messiaen, L.M.1
Callens, T.2
Mortier, G.3
Beysen, D.4
Vandenbroucke, I.5
Van Roy, N.6
Speleman, F.7
Paepe, A.D.8
-
36
-
-
34247137233
-
Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations
-
Metzner, A., Horstmann, M.A., Fehse, B., Ortmeyer, G., Niemeyer, C.M., Stocking, C., Mayr, G.W. Jucker, M. (2007) Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations. Gene Therapy, 14, 699 703.
-
(2007)
Gene Therapy
, vol.14
, pp. 699-703
-
-
Metzner, A.1
Horstmann, M.A.2
Fehse, B.3
Ortmeyer, G.4
Niemeyer, C.M.5
Stocking, C.6
Mayr, G.W.7
Jucker, M.8
-
37
-
-
13844265841
-
Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations
-
Mohi, M.G., Williams, I.R., Dearolf, C.R., Chan, G., Kutok, J.L., Cohen, S., Morgan, K., Boulton, C., Shigematsu, H., Keilhack, H., Akashi, K., Gilliland, D.G. Neel, B.G. (2005) Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations. Cancer Cell, 7, 179 191.
-
(2005)
Cancer Cell
, vol.7
, pp. 179-191
-
-
Mohi, M.G.1
Williams, I.R.2
Dearolf, C.R.3
Chan, G.4
Kutok, J.L.5
Cohen, S.6
Morgan, K.7
Boulton, C.8
Shigematsu, H.9
Keilhack, H.10
Akashi, K.11
Gilliland, D.G.12
Neel, B.G.13
-
38
-
-
5644284103
-
HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2)
-
Morerio, C., Acquila, M., Rosanda, C., Rapella, A., Dufour, C., Locatelli, F., Maserati, E., Pasquali, F. Panarello, C. (2004) HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2). Cancer Research, 64, 2649 2651.
-
(2004)
Cancer Research
, vol.64
, pp. 2649-2651
-
-
Morerio, C.1
Acquila, M.2
Rosanda, C.3
Rapella, A.4
Dufour, C.5
Locatelli, F.6
Maserati, E.7
Pasquali, F.8
Panarello, C.9
-
39
-
-
34548121797
-
Chronic myeloproliferative disorders
-
In: ed. by. C.H. Pui. pp. Cambridge University Press, New York.
-
Niemeyer, C.M. Locatelli, F. (2006) Chronic myeloproliferative disorders. In : Childhood Leukemia (ed. by C.H. Pui pp. 571 598. Cambridge University Press, New York.
-
(2006)
Childhood Leukemia
, pp. 571-598
-
-
Niemeyer, C.M.1
Locatelli, F.2
-
40
-
-
0030977399
-
Chronic myelomonocytic leukemia in childhood: A retrospective analysis of 110 cases. European Working Group on myelodysplastic syndromes in childhood (EWOG-MDS)
-
Niemeyer, C.M., Aricò, M., Basso, G., Biondi, A., Cantu Rajnoldi, A., Creutzig, U., Haas, O., Harbott, J., Hasle, H., Kerndrup, G., Locatelli, F., Mann, G., Stollmann-Gibbels, B., van't Veer-Korthof, E.T., van Wering, E. Zimmermann, M. (1997) Chronic myelomonocytic leukemia in childhood: a retrospective analysis of 110 cases. European Working Group on myelodysplastic syndromes in childhood (EWOG-MDS). Blood, 89, 3534 3543.
-
(1997)
Blood
, vol.89
, pp. 3534-3543
-
-
Niemeyer, C.M.1
Aricò, M.2
Basso, G.3
Biondi, A.4
Cantu Rajnoldi, A.5
Creutzig, U.6
Haas, O.7
Harbott, J.8
Hasle, H.9
Kerndrup, G.10
Locatelli, F.11
Mann, G.12
Stollmann-Gibbels, B.13
Van'T Veer-Korthof, E.T.14
Van Wering, E.15
Zimmermann, M.16
-
41
-
-
0142099097
-
Differentiating juvenile myelomonocytic leukemia from infectious disease
-
Niemeyer, C.M., Fenu, S., Hasle, H., Mann, G., Stary, J. van Wering, E. (1998) Differentiating juvenile myelomonocytic leukemia from infectious disease. Blood, 91, 365 367.
-
(1998)
Blood
, vol.91
, pp. 365-367
-
-
Niemeyer, C.M.1
Fenu, S.2
Hasle, H.3
Mann, G.4
Stary, J.5
Van Wering, E.6
-
42
-
-
27644504641
-
RAS-blocking bisphosphonate zoledronic acid inhibits the abnormal proliferation and differentiation of juvenile myelomonocytic leukemia cells in vitro
-
Ohtsuka, Y., Manabe, A., Kawasaki, H., Hasegawa, D., Zaike, Y., Watanabe, S., Tanizawa, T., Nakahata, T. Tsuji, K. (2005) RAS-blocking bisphosphonate zoledronic acid inhibits the abnormal proliferation and differentiation of juvenile myelomonocytic leukemia cells in vitro. Blood, 106, 3134 3141.
-
(2005)
Blood
, vol.106
, pp. 3134-3141
-
-
Ohtsuka, Y.1
Manabe, A.2
Kawasaki, H.3
Hasegawa, D.4
Zaike, Y.5
Watanabe, S.6
Tanizawa, T.7
Nakahata, T.8
Tsuji, K.9
-
43
-
-
0030989159
-
Loss of heterozygosity at the N-ras locus in 7,12-dimethylbenz[a] anthracene-induced rat leukemia
-
Osaka, M., Matsuo, S., Koh, T. Sugiyama, T. (1997) Loss of heterozygosity at the N-ras locus in 7,12-dimethylbenz[a] anthracene-induced rat leukemia. Molecular Carcinogenesis, 18, 206 212.
-
(1997)
Molecular Carcinogenesis
, vol.18
, pp. 206-212
-
-
Osaka, M.1
Matsuo, S.2
Koh, T.3
Sugiyama, T.4
-
44
-
-
22044452124
-
Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells
-
Schubbert, S., Lieuw, K., Rowe, S.L., Lee, C.M., Li, X., Loh, M.L., Clapp, D.W. Shannon, K.M. (2005) Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells. Blood, 106, 311 317.
-
(2005)
Blood
, vol.106
, pp. 311-317
-
-
Schubbert, S.1
Lieuw, K.2
Rowe, S.L.3
Lee, C.M.4
Li, X.5
Loh, M.L.6
Clapp, D.W.7
Shannon, K.M.8
-
45
-
-
0037376751
-
B lineage acute lymphoblastic leukemia transformation in a child with juvenile myelomonocytic leukemia, type 1 neurofibromatosis and monosomy of chromosome 7. Possible implications in the leukemogenesis
-
Scrideli, C.A., Baruffi, M.R., Rogatto, S.R., Valera, E.T., Defavery, R. Tone, L.G. (2003) B lineage acute lymphoblastic leukemia transformation in a child with juvenile myelomonocytic leukemia, type 1 neurofibromatosis and monosomy of chromosome 7. Possible implications in the leukemogenesis. Leukemia Research, 27, 371 374.
-
(2003)
Leukemia Research
, vol.27
, pp. 371-374
-
-
Scrideli, C.A.1
Baruffi, M.R.2
Rogatto, S.R.3
Valera, E.T.4
Defavery, R.5
Tone, L.G.6
-
46
-
-
0030724855
-
Mutations of the RAS genes in childhood acute myeloid leukemia, myelodysplastic syndrome and juvenile chronic myelocytic leukemia
-
Sheng, X.M., Kawamura, M., Ohnishi, H., Ida, K., Hanada, R., Kojima, S., Kobayashi, M., Bessho, F., Yanagisawa, M. Hayashi, Y. (1997) Mutations of the RAS genes in childhood acute myeloid leukemia, myelodysplastic syndrome and juvenile chronic myelocytic leukemia. Leukemia Research, 21, 697 701.
-
(1997)
Leukemia Research
, vol.21
, pp. 697-701
-
-
Sheng, X.M.1
Kawamura, M.2
Ohnishi, H.3
Ida, K.4
Hanada, R.5
Kojima, S.6
Kobayashi, M.7
Bessho, F.8
Yanagisawa, M.9
Hayashi, Y.10
-
47
-
-
23844478260
-
Little response to zoledronic acid in a child of juvenile myelomonocytic leukemia (JMML) harboring the PTPN11 mutation
-
Shimada, H., Shima, H., Shimasaki, N., Yoshihara, H., Mori, T. Takahashi, T. (2005) Little response to zoledronic acid in a child of juvenile myelomonocytic leukemia (JMML) harboring the PTPN11 mutation. Annals of Oncology, 16, 1400.
-
(2005)
Annals of Oncology
, vol.16
, pp. 1400
-
-
Shimada, H.1
Shima, H.2
Shimasaki, N.3
Yoshihara, H.4
Mori, T.5
Takahashi, T.6
-
48
-
-
0030947237
-
Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders
-
Side, L., Taylor, B., Cayouette, M., Conner, E., Thompson, P., Luce, M. Shannon, K.M. (1997) Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders. New England Journal of Medicine, 336, 1713 1720.
-
(1997)
New England Journal of Medicine
, vol.336
, pp. 1713-1720
-
-
Side, L.1
Taylor, B.2
Cayouette, M.3
Conner, E.4
Thompson, P.5
Luce, M.6
Shannon, K.M.7
-
49
-
-
0032125716
-
Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1
-
Side, L.E., Emanuel, P.D., Taylor, B., Franklin, J., Thompson, P., Castleberry, R.P. Shannon, K.M. (1998) Mutations of the NF1 gene in children with juvenile myelomonocytic leukemia without clinical evidence of neurofibromatosis, type 1. Blood, 92, 267 272.
-
(1998)
Blood
, vol.92
, pp. 267-272
-
-
Side, L.E.1
Emanuel, P.D.2
Taylor, B.3
Franklin, J.4
Thompson, P.5
Castleberry, R.P.6
Shannon, K.M.7
-
50
-
-
0036183285
-
National Marrow Donor Program. Unrelated donor bone marrow transplantation for children with juvenile myelomonocytic leukaemia
-
Smith, F.O., King, R., Nelson, G., Wagner, J.E., Robertson, K.A., Sanders, J.E., Bunin, N., Emaunel, P.D. Davies, S.M. (2002) National Marrow Donor Program. Unrelated donor bone marrow transplantation for children with juvenile myelomonocytic leukaemia. British Journal of Haematology, 116, 716 724.
-
(2002)
British Journal of Haematology
, vol.116
, pp. 716-724
-
-
Smith, F.O.1
King, R.2
Nelson, G.3
Wagner, J.E.4
Robertson, K.A.5
Sanders, J.E.6
Bunin, N.7
Emaunel, P.D.8
Davies, S.M.9
-
51
-
-
0027974256
-
Neurofibromatosis and childhood leukemia/lymphoma: A population-based UKCCSG study
-
Stiller, C.A., Chessells, J.M. Fitchett, M. (1994) Neurofibromatosis and childhood leukemia/lymphoma: a population-based UKCCSG study. British Journal of Cancer, 70, 969 972.
-
(1994)
British Journal of Cancer
, vol.70
, pp. 969-972
-
-
Stiller, C.A.1
Chessells, J.M.2
Fitchett, M.3
-
52
-
-
18344385476
-
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
-
Tartaglia, M., Mehler, E.L., Goldberg, R., Zampino, G., Brunner, H.G., Kremer, H., van der Burgt, I., Crosby, A.H., Ion, A., Jeffery, S., Kalidas, K., Patton, M.A., Kucherlapati, R.S. Gelb, B.D. (2001) Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome. Nature Genetics, 29, 465 468.
-
(2001)
Nature Genetics
, vol.29
, pp. 465-468
-
-
Tartaglia, M.1
Mehler, E.L.2
Goldberg, R.3
Zampino, G.4
Brunner, H.G.5
Kremer, H.6
Van Der Burgt, I.7
Crosby, A.H.8
Ion, A.9
Jeffery, S.10
Kalidas, K.11
Patton, M.A.12
Kucherlapati, R.S.13
Gelb, B.D.14
-
53
-
-
0038278866
-
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia
-
Tartaglia, M., Niemeyer, C.M., Fragale, A., Song, X., Buechner, J., Jung, A., Hählen, K., Hasle, H., Licht, J.D. Gelb, B.D. (2003) Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia. Nature Genetics, 34, 148 150.
-
(2003)
Nature Genetics
, vol.34
, pp. 148-150
-
-
Tartaglia, M.1
Niemeyer, C.M.2
Fragale, A.3
Song, X.4
Buechner, J.5
Jung, A.6
Hählen, K.7
Hasle, H.8
Licht, J.D.9
Gelb, B.D.10
-
54
-
-
27144432878
-
Val617Phe activating tyrosine kinase mutation in juvenile myelomonocytic leukemia
-
JAK2 (
-
Tono, C., Xu, G., Toki, T., Takahashi, Y., Sasaki, S., Terui, K. Ito, E. JAK2 (2005) Val617Phe activating tyrosine kinase mutation in juvenile myelomonocytic leukemia. Leukemia, 19, 1843 1844.
-
(2005)
Leukemia
, vol.19
, pp. 1843-1844
-
-
Tono, C.1
Xu, G.2
Toki, T.3
Takahashi, Y.4
Sasaki, S.5
Terui, K.6
Ito, E.7
-
55
-
-
0037080290
-
Prospective study of 90 children requiring treatment for juvenile myelomonocytic leukemia or myelodysplastic syndrome: A report from the Children's Cancer Group
-
Woods, W.G., Barnard, D.R., Alonzo, T.A., Buckley, J.D., Kobrinsky, N., Arthur, D.C., Sanders, J., Neudorf, S., Gold, S. Lange, B.J. (2002) Prospective study of 90 children requiring treatment for juvenile myelomonocytic leukemia or myelodysplastic syndrome: a report from the Children's Cancer Group. Journal of Clinical Oncology, 20, 434 440.
-
(2002)
Journal of Clinical Oncology
, vol.20
, pp. 434-440
-
-
Woods, W.G.1
Barnard, D.R.2
Alonzo, T.A.3
Buckley, J.D.4
Kobrinsky, N.5
Arthur, D.C.6
Sanders, J.7
Neudorf, S.8
Gold, S.9
Lange, B.J.10
-
56
-
-
0037369296
-
Successful treatment of juvenile myelomonocytic leukemia relapsing post stem cell transplant using donor lymphocyte infusion
-
Worth, A., Rao, K., Webb, D., Chessells, J., Passmore, J. Veys, P. (2003) Successful treatment of juvenile myelomonocytic leukemia relapsing post stem cell transplant using donor lymphocyte infusion. Blood, 101, 1713 1714.
-
(2003)
Blood
, vol.101
, pp. 1713-1714
-
-
Worth, A.1
Rao, K.2
Webb, D.3
Chessells, J.4
Passmore, J.5
Veys, P.6
-
57
-
-
20044376886
-
Chimaerism analyses and subsequent immunological intervention after stem cell transplantation in patients with juvenile myelomonocytic leukaemia
-
Yoshimi, A., Niemeyer, C.M., Bohmer, V., Duffner, U., Strahm, B., Kreyenberg, H., Dilloo, D., Zintl, F., Claviez, A., Wossmann, W., Kremens, B., Holter, W., Niethammer, D., Beck, J.F., Kontny, U., Nollke, P., Klingebiel, T. Bader, P. (2005a) Chimaerism analyses and subsequent immunological intervention after stem cell transplantation in patients with juvenile myelomonocytic leukaemia. British Journal of Haematology, 129, 542 549.
-
(2005)
British Journal of Haematology
, vol.129
, pp. 542-549
-
-
Yoshimi, A.1
Niemeyer, C.M.2
Bohmer, V.3
Duffner, U.4
Strahm, B.5
Kreyenberg, H.6
Dilloo, D.7
Zintl, F.8
Claviez, A.9
Wossmann, W.10
Kremens, B.11
Holter, W.12
Niethammer, D.13
Beck, J.F.14
Kontny, U.15
Nollke, P.16
Klingebiel, T.17
Bader, P.18
-
58
-
-
20044393759
-
European Working Group of MDS in childhood (EWOG-MDS). Donor leukocyte infusion after hematopoietic stem cell transplantation in patients with juvenile myelomonocytic leukemia
-
Yoshimi, A., Bader, P., Matthes-Martin, S., Stary, J., Sedlacek, P., Duffner, U., Klingebiel, T., Dilloo, D., Holter, W., Zintl, F., Kremens, B., Sykora, K.W., Urban, C., Hasle, H., Korthof, E., Revesz, T., Fischer, A., Nollke, P., Locatelli, F. Niemeyer, C.M. (2005b) European Working Group of MDS in childhood (EWOG-MDS). Donor leukocyte infusion after hematopoietic stem cell transplantation in patients with juvenile myelomonocytic leukemia. Leukemia, 19, 971 977.
-
(2005)
Leukemia
, vol.19
, pp. 971-977
-
-
Yoshimi, A.1
Bader, P.2
Matthes-Martin, S.3
Stary, J.4
Sedlacek, P.5
Duffner, U.6
Klingebiel, T.7
Dilloo, D.8
Holter, W.9
Zintl, F.10
Kremens, B.11
Sykora, K.W.12
Urban, C.13
Hasle, H.14
Korthof, E.15
Revesz, T.16
Fischer, A.17
Nollke, P.18
Locatelli, F.19
Niemeyer, C.M.20
more..
-
59
-
-
33847184613
-
Second allogeneic hematopoietic stem cell transplantation (HSCT) results in outcome similar to that of first HSCT for patients with juvenile myelomonocytic leukemia
-
Yoshimi, A., Mohamed, M., Bierings, M., Urban, C., Korthof, E., Zecca, M., Sykora, K.W., Duffner, U., Trebo, M., Matthes-Martin, S., Sedlacek, P., Klingebiel, T., Lang, P., Fuhrer, M., Claviez, A., Wossmann, W., Pession, A., Arvidson, J., O'Marcaigh, A.S., van den Heuvel-Eibrink, M.M., Stary, J., Hasle, H., Nollke, P., Locatelli, F. Niemeyer, C.M. (2007) Second allogeneic hematopoietic stem cell transplantation (HSCT) results in outcome similar to that of first HSCT for patients with juvenile myelomonocytic leukemia. Leukemia, 21, 556 560.
-
(2007)
Leukemia
, vol.21
, pp. 556-560
-
-
Yoshimi, A.1
Mohamed, M.2
Bierings, M.3
Urban, C.4
Korthof, E.5
Zecca, M.6
Sykora, K.W.7
Duffner, U.8
Trebo, M.9
Matthes-Martin, S.10
Sedlacek, P.11
Klingebiel, T.12
Lang, P.13
Fuhrer, M.14
Claviez, A.15
Wossmann, W.16
Pession, A.17
Arvidson, J.18
O'Marcaigh, A.S.19
Van Den Heuvel-Eibrink, M.M.20
Stary, J.21
Hasle, H.22
Nollke, P.23
Locatelli, F.24
Niemeyer, C.M.25
more..
|