Inhibition of proliferation and induction of apoptosis in juvenile myelomonocytic leukemic cells by the granulocyte-macrophage colony- stimulating factor analogue E21R

Blood

Volumn 88, Issue 7, 1996, Pages 2634-2639

  Iversen, Per O ^b   Rodwell, Robyn L ^b   Pitcher, Lydia ^b   Taylor, Kerry M ^b   Lopez, Angel F ^a  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

E 21R; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHILD; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; DRUG EFFECT; FEMALE; HUMAN; HUMAN CELL; MALE; MYELOMONOCYTIC LEUKEMIA; PRIORITY JOURNAL;

EID: 0029796382     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.7.2634.bloodjournal8872634     Document Type: Article

References (29)

1. Castro-Malaspina H, Schaison G, Passe S, Pasquier A, Berger R, Bayle-Weisgerber C, Miller D, Seligmann M, Bernard J: Subacute and chronic myelomonocytic leukemia in children (juvenile CML). Cancer 54:675, 1984
2. Busque L, Gilliland DG, Prchal JT, Sieff CA, Weinstein HJ, Sokol JM, Belickova M, Wayne AS, Zuckerman KS, Sokol L, Castleberry RP, Emanuel PD: Clonality in juvenile chronic myelogenous leukemia. Blood 85:21, 1995
3. Lau RC, Squire J, Brisson L, Kamel-Reid S, Grunberger T, Dube I, Letarte M. Shannon K, Freedman MH: Lymphoid blast crisis of B-lineage phenotype with monosomy 7 in a patient with juvenile chronic myelogenous leukemia (JCML). Leukemia 8:903, 1994
4. Chan HSL, Estrov Z, Weitzman SS, Freedman MH: The value of intensive combination chemotherapy for juvenile chronic myelogenous leukemia. J Clin Oncol 5:1960, 1987
5. Castleberry RP, Emanuel PD, Zuckerman KS, Cohn S, Strauss L, Byrd RL, Homans A, Chaffee S, Nitschke R, Gualtieri RJ: A pilot study of isoretinoin in the treatment of juvenile chronic myelogenous leukemia. N Engl J Med 331:1680, 1994
6. Sanders JE, Buckner CD, Thomas ED, Fleischer R, Sullivan KM, Appelbaum FA, Storb R: Allogeneic marrow transplantation for children with juvenile chronic myelogenous leukemia. Blood 71:1144, 1988
7. Gualtieri RJ, Emanuel PD, Zuckerman KS, Martin G, Clark SC, Shadduck RK, Dracker RA, Akabutu J, Nitschke R, Hetherington ML, Dickerman JD, Hakami N, Castleberry RP: Granulocyte-macrophage colony-stimulating factor is an endogeneous regulator of cell proliferation in juvenile chronic myelogenous leukemia. Blood 74:2360, 1989
8. Freedman MH, Cohen A, Grunberger T, Bunin N, Luddy RE, Saunders EF, Shahidi N, Lau A, Estrov Z: Central role of tumour necrosis factor, GM-CSF, and interleukin 1 in the pathogenesis of juvenile chronic myelogenous leukaemia. Br J Haematol 80:40, 1992
9. Attias D, Grunberger T, Vanek W, Estrov Z, Cohen A, Lau R, Freedman MH: B-lineage lymphoid blast crisis in juvenile chronic myelogenous leukemia: II interleukin-1-mediated autocrine growth regulation of the lymphoblasts. Leukemia 9:884, 1995
10. Emanuel PD, Bates LJ, Castleberry RP, Gualtieri RJ, Zuckerman KS: Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors. Blood 77:925, 1991
11. Largaespada DA, Brannan CI, Jenkins NA, Copeland NG: NF1 deficiency causes Ras-mediated granulocyte-macrophage colony-stimulating factor hypersensitivity and chronic myeloid leukaemia. Nat Genet 12:137, 1996
12. Bollag G, Clapp DW, Shih S, Adler F, Zhang YY, Thompson P, Lange BJ, Freedman MH, McCormick F, Jacks T, Shannon K: Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells. Nat Genet 12:144, 1996
13. Lopez AF, Elliott MJ, Woodcock J, Vadas MA: GM-CSF, IL-3 and IL-5: cross-competition on human haemopoietic cells. Immunol Today 13:495, 1992
14. Hercus TR, Bagley CJ, Cambareri B, Dottore M, Woodcock JM, Vadas MA, Shannon MF, Lopez AF: Specific human granulocyte-macrophage colony-stimulating factor antagonists. Proc Natl Acad Sci USA 91:5838, 1994
15. Iversen PO, To LB, Lopez AF: Apoptosis of hemopoietic cells by the human granulocyte-macrophage colony-stimulating factor mutant E21R. Proc Natl Acad Sci USA 93:2785, 1996
16. Korpelainen EI, Gamble JR, Smith WB, Goodall GJ, Qiyu S, Woodcock JM, Dottore M, Vada MA, Lopez AF: The receptor for interleukin 3 is selectively induced in human endothelial cells by tumor necrosis factor a and potentiates interleukin 8 secretion and neutrophil transmigration. Proc Natl Acad Sci USA 90:11137, 1993
17. Woodcock JM, Zacharakis B, Plaetinck G, Bagley CJ, Qiuy S, Hercus TR, Tavernier J, Lopez AF: Three residues in the common β chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. EMBO J 13:5176, 1994
18. Haylock DN, To LB, Dowse TL, Juttner CA, Simmons PJ: Ex vivo expansion and maturation of peripheral blood CD34+ cells into the myeloid lineage. Blood 80:1405, 1992
19. Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C: A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139:271, 1991
20. Lotem J, Cragoe Jr. EJ, Sachs L: Rescue from programmed cell death in leukemic and normal myeloid cells. Blood 78:953, 1991
21. Cohen JJ: Apoptosis. Immunol Today 14:126, 1993
22. Wyllie AH: Glucocorticoid-induced thymocyte apoptosis is associated with endogeneous endonuclease activation. Nature 284:555, 1980
23. Baby GC Jr, DinarelloCA, Neerhout RC, Ridgway D, McCall E: Interleukin 1-dependent paracrine granulopoiesis in chronic granulocytic leukemia of the juvenile type. J Clin Invest 82:1430, 1988
24. Levy Y, Tsapis A, Brouet J-C: Interleukin-6 antisense oligonucleotides inhibit the growth of human myeloma cell lines. J Clin Invest 88:696, 1991
25. Kinoshita T, Yokota T, Arai K, Miyajima A: Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors. EMBO J 14:266, 1995
26. Inhorn RC, Carlesso N, Durstin M, Frank DA, Griffin JD: Identification of a viability domain in the granulocyte-macrophage colony-stimulating factor receptor β-chain involving tyrosine-750. Proc Natl Acad Sci USA 92:8665, 1995
27. Miyauchi J, Asada M, Sasaki M, Tsunematsu Y, Kojima S, Mizutani S: Mutations of the N-ras gene in juvenile chronic myelogenous leukemia. Blood 83:2248, 1994
28. Schiro R, Longoni D, Rossi V, Maglia O, Doni A, Arsura M, Carrara G, Masera G, Vannier E, Dinarello CA, Rambaldi A, Blondi A: Suppression of juvenile chronic myelogenous leukemia colony growth by interleukin-1 receptor antagonist. Blood 83:460, 1994
29. Emanuel PD, Bates LJ, Zhu S-W, Castleberry RP, Gualtieri RJ, Zuckerman KS: The role of monocyte-derived hemopoietic growth factors in the regulation of myeloproliferation in juvenile chronic myelogenous leukemia. Exp Hematol 19:1017, 1991