Serum-induced membrane depolarization in quiescent fibroblasts: Activation of a chloride conductance through the G protein-coupled LPA receptor

EMBO Journal

Volumn 15, Issue 1, 1996, Pages 63-72

  Postma, Friso R ^a   Jalink, Kees ^a,c   Hengeveld, Trudi ^a   Bot, Alice G M ^b   Alblas, Jacqueline ^a   De Jonge, Hugo R ^b   Moolenaar, Wouter H ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chloride current; Fibroblasts; G protein coupled receptor; Lysophosphatidic acid; Membrane depolarization

Indexed keywords

ACTIN; ALBUMIN; CHLORIDE ION; ENDOTHELIN RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; LYSOPHOSPHATIDIC ACID; MEMBRANE RECEPTOR; NEUROPEPTIDE; PHOSPHOLIPASE C; TACHYKININ RECEPTOR; THROMBIN; THROMBIN RECEPTOR;

ANIMAL CELL; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CHLORIDE CONDUCTANCE; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; FIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SERUM;

ANIMALIA;

EID: 0030048805     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00334.x     Document Type: Article

References (46)

1. Alblas, J , van Etten, I., Khanum, A. and Moolenaar, W.H (1995) C-Terminal truncation of the neurokinin-2 receptor causes enhanced and sustained agonist-induced signaling. Role of receptor phosphorylation in signal attenuation. J. Biol. Chem., 270, 8944-8951.
2. 2 inhibit release of free arachidonic acid in thrombin-stimulaled platelets. J Biol. Chem., 269, 15625-15630.
3. Cao, G., Kuhn, A. and Dalbey, R.E. (1995) The translocation of negatively charged residues across the membrane is driven by the electrochemical potential: evidence for electrophoresis-like membrane transfer mechanism. EMBO J., 14, 866-875.
4. Chen, C., Corbley, M.J., Roberts, T M and Hess, P. (1988) Voltage-sensitive calcium channels in normal and transformed 3T3 fibroblasts. Science, 239, 1024-1026.
5. Chrzanowska-Wodnicka, M. and Burridge, K. (1994) Tyrosine phosphorylation is involved in reorganization of the actin cytoskeleton in response to serum and LPA stimulation. J. Cell Sci., 107, 3643-3654.
6. Clancy, J.P., McCann, J.D., Li, M and Welsh, M.J. (1990) Calcium-dependent regulation of airway epithelial chloride channels. Am. J. Physiol., 258, L25-L32.
7. Davis, P.D. et al. (1989) Potent selective inhibitors of protein kinase C. FEBS Lett., 259, 61-63
8. 2+ changes in human neutrophils J. Biol. Chem., 262, 4574-4579.
9. Eichholtz, T., Jalink, K., Fahrenfort, I. and Moolenaar, W.H. (1993) The bioactive phospholipid lysophosphatidic acid is released by activated platelets. Biochem. J., 291, 677-680.
10. Ford-Hutchinson, A.W., Gresser, M. and Young, R.N. (1994) 5-Lipoxygenase. Annu. Rev. Biochem., 63, 383-417.
11. Frace, A M and Gargus, J J. (1989) Activation of single-channel currents in mouse fibroblasts by platelet-derived growth factor. Proc. Natl Acad. Sci. USA, 86, 2511-2515.
12. Haslberger, A., Romanin, C and Koerber, R (1992) Membrane potential modulates release of tumor necrosis factor in lipopolysaccharide-stimulated mouse macrophages. Mol. Cell. Biol., 3, 451-460.
13. Hoffman, E.P., Lehmann-Horn, F. and Rude, R. (1995) Overexcited or inactive: ion channels in muscle disease Cell, 80, 681-686.
14. Hordijk, P.L., Verlaan, I , van Corven, E.J. and Moolenaar, W.H (1994) Protein tyrosine phosphorylation induced by lysophosphatidic acid in Rat-1 fibroblasts. J. Biol. Chem., 269, 645-651.
15. Hülser, D.F. and Frank, W. (1971) Stimulation of embryonic rat cells by a protein fraction isolated from fetal calf serum: electrophysiological measurements at the cell surface membrane. Z. Naturforsch., 26b, 1045-1048.
16. Jalink, K. and Mootenaar, W.H (1992) Thrombin receptor activation causes rapid neural cell rounding and neunte retraction independent of classic second messengers J Cell Biol., 118, 411-419.
17. Jalink, K., Hordijk, P.L. and Moolenaar, W.H. (1994) Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator. Biochim. Biophys. Acta, 1198, 185-196.
18. Janssen, L.J. and Sims, S.M. (1992) Acetylcholine activates non-selective cation and chloride conductances in canine and guinea-pig tracheal myocytes. J. Physiol., 453, 197-218.
19. Jentsch, T.J. (1994) Molecular physiology of anion channels. Curr. Opin. Cell Biol., 6, 600-606.
20. Kahn, R.A. (1991) Fluoride is not an activator of the smaller (20-25 kDa) GTP-binding proteins. J. Biol. Chem., 266, 15595-15597
21. Kamugai, N , Morii, N., Fujisawa, K., Nemoto, Y. and Narumiya, S. (1993) ADP-ribosylation of rho p21 inhibits lysophosphatidic acid-induced protein tyrosine phosphorylation and phosphatidylinositol 3-kinase activation in cultured Swiss 3T3 cells. J. Biol. Chem., 268, 24535-24538.
22. Kremer, S G., Breuer, W.V. and Skorecki, K.L. (1989) Vasoconstrictor hormones depolarize renal glomerular mesangial cells by activating chloride channels. J. Cell. Physiol., 138, 97-105.
23. - transport in human fibroblasts. Am J. Physiol., 255, C112-C122.
24. Lovisolo, D., Munaron, L., Baccino, F.M. and Bonelli, G. (1992) Potassium and calcium currents activated by fetal calf serum in Balb-c 3T3 fibroblasts. Biochim. Biophys. Acta, 1112, 241-245.
25. Lytton, J., Westlin, M. and Hanley, M.R. (1991) Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps J. Biol. Chem , 266, 17067-17071
26. Moolenaar, W.H (1995a) Lysophosphatidic acid signalling. Curr Opin. Cell Biol., 7, 203-210.
27. Moolenaar, W.H. (1995b) Lysophosphatidic acid, a multifunctional phospholipid messenger J. Biol. Chem., 270, 12949-12952.
28. Moolenaar, W H , Mummery, C L., van der Saag, P.T. and de Laat, S.W. (1981) Rapid ionic events and the initiation of growth in serum-stimulated neuroblastoma cells. Cell, 23, 789-798.
29. + influx in human fibroblasts. J. Biol. Chem., 257, 8502-8506.
30. Otero, A.S., Yi, X.B., Gray, M.C., Szabo, G. and Hewlett, E.L. (1995) Membrane depolarization prevents cell invasion by Bordetella pertussis adenylate cyclase toxin. J. Biol. Chem., 270, 9695-9697
31. Rae, J., Cooper, K., Gates, P. and Watsky, M. (1991) Low access resistance perforated patch recordings using amphotericin B. J. Neurosci. Meth., 37, 15-26.
32. Ridley, A.J and Hall, A. (1992) The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibres in response to growth factors. Cell, 70, 389-399.
33. Rouzer, C.A., Ford-Hutchinson, A.W., Morton, H.E. and Gillard, J.W. (1990) MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes J. Biol Chem., 265, 1436-1442.
34. Seckl, M.J., Seufferlein, T. and Rozengurt, E. (1994) Lysophosphatidic acid-depleted serum, hepatocyte growth factor and stem cell growth factor stimulate colony growth of small cell lung cancer cells through a calcium-independent pathway. Cancer Res , 54, 6143-6147.
35. Seufferlein, T. and Rozengurt, E. (1994) Lysophosphatidic acid stimulates tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130. J. Biol. Chem., 269, 9345-9351.
36. 2+-ATPase. Proc. Natl Acad. Sci. USA, 87, 2466-2470.
37. Thompson, A.K., Mostafapour, S.P., Denlinger, L.C., Bleasdale, J.E. and Fisher, S.K. (1991) The aminosteroid U-731222 inhibits muscarinic receptor sequestration and phosphoinositide hydrolysis in SK-N-SH neuroblastoma cells. J. Biol. Chem., 266, 23856-23862.
38. Tigyi, G. and Miledi, R. (1992) Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neunte retraction in PC12 pheochromocytoma cells. J. Biol. Chem., 267, 21360-21367.
39. 2+ and cAMP activate different chloride efflux pathways in HT-29 colonic epithelial cell line. Am. J. Physiol., 261, G958-G965.
40. Van Corven, E.J., Groenink, A., Jalink, K., Eichholtz, T. and Moolenaar, W.H. (1989) Lysophosphatidate-induced cell proliferation: identification and dissection of G protein-mediated signaling pathways. Cell, 59, 45-54.
41. Van Corven, E.J., van Rijswijk, A., Jalink, K , van der Bend, R.L , van Blitterswijk, W.J and Moolenaar, W.H. (1992) Mitogenic action of lysophosphatidic acid and phosphatidic acid on fibroblasts. Biochem. J., 281, 163-169.
42. Van der Bend, R.L., de Widt, J , van Corven, E.J., Moolenaar, W.H. and van Blitterswijk, W.J. (1992) The biologically active phospholipid, lysophosphatidic acid, induces phosphatidylcholine breakdown in fibroblasts via activation of phospholipase D. Biochem. J., 285, 235-240.
43. v-src alters the ionic permeability of the plasma membrane in rat cells. J.Biol. Chem., 262, 2431-2434.
44. Van Renterghem, C. and Lazdunski, M. (1993) Endothelin and vasopressin activate low conductance chloride channels in aortic smooth muscle cells. Pflügers Arch , 425, 156-163.
45. Welsh, M.J. and Smith, A.E. (1993) Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell, 73, 1251-1254.
46. - channels in Xenopus oocytes. Mol. Pharmacol., 37, 720-724.