A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting

Nature Neuroscience

Volumn 6, Issue 6, 2003, Pages 572-578

  Bräuer, Anja U ^a   Savaskan, Nicolai E ^a   Kühn, Hartmut ^a   Prehn, Siegfried ^a   Ninnemann, Olaf ^a   Nitsch, Robert ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDATE PHOSPHATASE; PHOSPHOLIPID; PROTEIN PRG 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; EMBRYO; EXTRACELLULAR SPACE; HIPPOCAMPUS; LIGAND BINDING; NERVE CELL DIFFERENTIATION; NERVE CELL MEMBRANE; NERVE FIBER GROWTH; NERVE REGENERATION; NERVE SPROUTING; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; BASE SEQUENCE; CELL DIFFERENTIATION; DNA, COMPLEMENTARY; EXTRACELLULAR SPACE; FEMALE; FETUS; GROWTH CONES; HIPPOCAMPUS; MEMBRANE LIPIDS; MICE; MOLECULAR SEQUENCE DATA; NERVE REGENERATION; NEURONAL PLASTICITY; ORGAN CULTURE TECHNIQUES; PHOSPHOLIPIDS; PHOSPHORIC MONOESTER HYDROLASES; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0038359758     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn1052     Document Type: Article

References (37)

1. Tessier-Lavigne, M. & Goodman, C.S. The molecular biology of axon guidance. Science 274, 1123-1133 (1996).
2. Goodman, C.S. Mechanisms and molecules that control growth cone guidance. Annu. Rev. Neurosci. 19, 341-377 (1996).
3. Super, H. & Soriano, E. The organization of the embryonic and early postnatal murine hippocampus. II. Development of entorhinal, commissural, and septal connections studied with the lipophilic tracer Dil. J. Comp. Neurol. 344, 101-120 (1994).
4. Cotman, C., Gentry, C. & Steward, O. Synaptic replacement in the dentate gyrus after unilateral entorhinal lesion: electron microscopic analysis of the extent of replacement of synapses by the remaining entorhinal cortex. J. Neurocytol. 6, 455-464 (1977).
5. Frotscher, M, Heimrich, B. & Deller, T. Sprouting in the hippocampus is layerspecific. Trends Neurosci. 20, 218-223 (1997).
6. Stein, E. & Tessier-Lavigne, M. Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex. Science 291, 1928-1938 (2001).
7. Colamarino, S.A. & Tessier-Lavigne, M. The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons. Cell 81, 621-629 (1995).
8. Kobayashi, H., Koppel, A.M., Luo, Y. & Raper, J.A. A role for collapsin-1 in olfactory and cranial sensory axon guidance. J. Neurosci. 17, 8339-8352 (1997).
9. Stein, E. et al. A role for the Eph ligand ephrin-A3 in entorhino-hippocampal axon targeting. J. Neurosci. 19, 8885-8893 (1999).
10. Steup, A. et al. Sema3C and netrin-1 differentially affect axon growth in the hippocampal formation. Mol. Cell. Neurosci. 15, 141-155 (2000).
11. Jalink, K. et al. Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J. Cell Biol. 126, 801-810 (1994).
12. Tigyi, G. et al. Lysophosphatidic acid-induced neurite retraction in PC12 cells: neurite-protective effects of cyclic AMP signaling. J. Neurochem. 66, 549-558 (1996).
13. Moolenaar, W.H. Development of our current understanding of bioactive lysophospholipids. Ann. NY Acad. Sci. 905, 1-10 (2000).
14. Skutella, T. & Nitsch, R. New molecules for hippocampal development. Trends Neurosci. 24, 107-113 (2001).
15. Savaskan, N.E. & Nitsch, R. Molecules involved in reactive sprouting in the hippocampus. Rev. Neurosci. 12, 195-215 (2001).
16. Jalink, K., Hordijk, P.L. & Moolenaar, W.H. Growth factor-like effects of lysophosphatidic acid, a novel lipid mediator. Biochim. Biophys. Acta 1198, 185-196 (1994).
17. Moolenaar, W.H. Lysophosphatidic acid signalling. Curr. Opin. Cell Biol. 7, 203-210 (1995).
18. Zhang, N., Zhang, J., Purcell, K.J., Cheng, Y. & Howard, K. The Drosophila protein Wunen repels migrating germ cells. Nature 385, 64-67 (1997).
19. Fukushima, N., Weiner, J.A. & Chun, J. Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology. Dev. Biol. 228, 6-18 (2000).
20. Neuwald, A.F. An unexpected structural relationship between integral membrane phosphatases and soluble haloperoxidases. Protein Sci. 6, 1764-1767 (1997).
21. Doren, M.V. & Lehmann, R. Cell migration: don't tread on me. Curr. Biol. 7, R148-R150 (1997).
22. Bräuer, A.U. et al. Molecular and functional analysis of hyperpolarizationactivated pacemaker channels in the hippocampus after entorhinal cortex lesion. FASEB J. 15, 2689-2701 (2001).
23. Bayer, S.A., Yackel, J.W. & Puri, P.S. Neurons in the rat dentate gyrus granular layer substantially increase during juvenile and adult life. Science 216, 890-892 (1982).
24. Deller, T., Frotscher, M. & Nitsch, R. Morphological evidence for the sprouting of inhibitory commissural fibers in response to the lesion of the excitatory entorhinal input to the rat dentate gyrus. J. Neurosci. 15, 6868-6878 (1995).
25. Jalink, K., Eichholtz, T., Postma, F.R., van Corven, E.J. & Moolenaar, W.H. Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: similarity to thrombin action. Cell Growth Differ, 4, 247-255 (1993).
26. Bothmer, J., Markerink, M. & Jolles, J. Brain phosphatidic acid and polyphosphoinositide formation in a broken cell preparation: regional distribution and the effect of age, Neurochem. Int. 21, 223-228 (1992).
27. Moolenaar, W.H., Kranenburg, O., Postma, F.R. & Zondag, G.C, Lysophosphatidic acid: G-protein signalling and cellular responses. Curr. Opin. Cell Biol. 9, 168-173 (1997).
28. Brindley, D.N. & Waggoner, D.W, Mammalian lipid phosphate phosphohydrolases. J. Biol. Chem. 273, 24281-24284 (1998).
29. Kanoh, H., Kai, M. & Wada, I. Phosphatidic acid phosphatase from mammalian tissues: discovery of channel-like proteins with unexpected functions, Biochim. Biophys. Acta 1348, 56-62 (1997).
30. Hla, T., Lee, M.J., Ancellin, N., Paik, J.H. & Kluk, M.J. Lysophospholipids - receptor revelations. Science 294, 1875-1878 (2001).
31. Bräuer, A.U., Savaskan, N.E., Plaschke, M., Ninnemann, O. & Nitsch, R. Perforant path lesion induces up-regulation of stathmin messenger RNA, but not SCG10 messenger RNA, in the adult rat hippocampus. Neuroscience 102, 515-526 (2001).
32. Meier, S. et al. Molecular analysis of Nogo genes in the hippocampus during develoment and following lesion and seizure. FASEB J. (Apr. 8, 2003).
33. Savaskan, N.E. et al. Outgrowth-promoting molecules in the adult hippocampus after perforant path lesion. Eur. J. Neurosci, 12, 1024-1032 (2000).
34. Savaskan, N.E. et al. Selenium deficiency increases susceptibility to glutamate-induced excitotoxicity. FASEB J. 17, 112-114 (2003).
35. Imai, A., Furui, T., Tamaya, T. & Mills, G.B. A gonadotropin-releasing hormoneresponsive phosphatase hydrolyses lysophosphatidic acid within the plasma membrane of ovarian cancer cells. J. Clin. Endocrinol. Metab. 85, 3370-3375 (2000).
36. Hooks, S.B. et al. Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent. J. Biol. Chem. 276, 4611-4621 (2001).
37. Brauer, A.U. et al. IG-molecule Kilon shows differential expression pattern from LAMP in the developing and adult rat hippocampus. Hippocampus 10, 632-644 (2000).