메뉴 건너뛰기




Volumn 25, Issue 8, 2004, Pages 1443-1448

The MTHFR 677C>T polymorphism is associated with an increased risk of hepatocellular carcinoma in patients with alcoholic cirrhosis

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CYSTEINE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); THREONINE; DNA; METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NAD);

EID: 4344703254     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh147     Document Type: Article
Times cited : (58)

References (37)
  • 2
    • 0022368621 scopus 로고
    • Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis
    • Niederau,C., Fischer,R., Sonnenberg,A., Stremmel,W., Trampisch,H.J. and Strohmeyer,G. (1985) Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis. N. Engl. J. Med., 313, 1256-1262.
    • (1985) N. Engl. J. Med. , vol.313 , pp. 1256-1262
    • Niederau, C.1    Fischer, R.2    Sonnenberg, A.3    Stremmel, W.4    Trampisch, H.J.5    Strohmeyer, G.6
  • 3
    • 0022637178 scopus 로고
    • Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency
    • Eriksson,S., Carlson,J. and Velez,R. (1986) Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency. N. Engl. J. Med., 314, 736-739.
    • (1986) N. Engl. J. Med. , vol.314 , pp. 736-739
    • Eriksson, S.1    Carlson, J.2    Velez, R.3
  • 4
    • 0030785082 scopus 로고    scopus 로고
    • Epidemiological characteristics and risk factors of hepatocellular carcinoma
    • Chen,C.J., Yu,M.W. and Liaw,Y.F. (1997) Epidemiological characteristics and risk factors of hepatocellular carcinoma. J. Gastroenterol. Hepatol., 12, S294-308.
    • (1997) J. Gastroenterol. Hepatol. , vol.12
    • Chen, C.J.1    Yu, M.W.2    Liaw, Y.F.3
  • 5
    • 0033755177 scopus 로고    scopus 로고
    • Genomic aberrations in human hepatocellular carcinomas of differing etiologies
    • Wong,N., Lai,P., Pang,E. et al. (2000) Genomic aberrations in human hepatocellular carcinomas of differing etiologies. Clin. Cancer Res., 6, 4000-4009.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 4000-4009
    • Wong, N.1    Lai, P.2    Pang, E.3
  • 6
    • 18644371590 scopus 로고    scopus 로고
    • Comprehensive allelotyping of well-differentiated human hepatocellular carcinoma with semiquantitative determination of chromosomal gain or loss
    • Nishimura,T., Nishida,N., Itoh,T., Kuno,M., Minata,M., Komeda,T., Fukuda,Y., Ikai,I., Yamaoka,Y. and Nakao,K. (2002) Comprehensive allelotyping of well-differentiated human hepatocellular carcinoma with semiquantitative determination of chromosomal gain or loss. Genes Chromosomes Cancer, 35, 329-339.
    • (2002) Genes Chromosomes Cancer , vol.35 , pp. 329-339
    • Nishimura, T.1    Nishida, N.2    Itoh, T.3    Kuno, M.4    Minata, M.5    Komeda, T.6    Fukuda, Y.7    Ikai, I.8    Yamaoka, Y.9    Nakao, K.10
  • 7
    • 0029080804 scopus 로고
    • Cytochrome P450 2E1 and glutathione S-transferase M1 polymorphisms and susceptibility to hepatocellular carcinoma
    • Yu,M.W., Gladek-Yarborough,A., Chiamprasert,S., Santella,R.M., Liaw,Y.F. and Chen,C.J. (1995) Cytochrome P450 2E1 and glutathione S-transferase M1 polymorphisms and susceptibility to hepatocellular carcinoma. Gastroenterology, 109, 1266-1273.
    • (1995) Gastroenterology , vol.109 , pp. 1266-1273
    • Yu, M.W.1    Gladek-Yarborough, A.2    Chiamprasert, S.3    Santella, R.M.4    Liaw, Y.F.5    Chen, C.J.6
  • 8
    • 0030927394 scopus 로고    scopus 로고
    • Lack of association of cytochrome P450 2E1 genetic polymorphisms with the risk of human hepatocellular carcinoma
    • Lee,H.S., Yoon,J.H., Kamimura,S., Iwata,K., Watanabe,H. and Kim,C.Y. (1997) Lack of association of cytochrome P450 2E1 genetic polymorphisms with the risk of human hepatocellular carcinoma. Int. J. Cancer, 71, 737-740.
    • (1997) Int. J. Cancer , vol.71 , pp. 737-740
    • Lee, H.S.1    Yoon, J.H.2    Kamimura, S.3    Iwata, K.4    Watanabe, H.5    Kim, C.Y.6
  • 9
    • 0032927750 scopus 로고    scopus 로고
    • Cytochrome P450 1A1 genetic polymorphisms and risk of hepatocellular carcinoma among chronic hepatitis B carriers
    • Yu,M.W., Chiu,Y.H., Yang,S.Y., Santella,R.M., Chern,H.D., Liaw,Y.F. and Chen,C.J. (1999) Cytochrome P450 1A1 genetic polymorphisms and risk of hepatocellular carcinoma among chronic hepatitis B carriers. Br. J. Cancer, 80, 598-603.
    • (1999) Br. J. Cancer , vol.80 , pp. 598-603
    • Yu, M.W.1    Chiu, Y.H.2    Yang, S.Y.3    Santella, R.M.4    Chern, H.D.5    Liaw, Y.F.6    Chen, C.J.7
  • 10
    • 0033119878 scopus 로고    scopus 로고
    • Plasma carotenoids, glutathione S-transferase M1 and T1 genetic polymorphisms and risk of hepatocellular carcinoma: Independent and interactive effects
    • Yu,M.W., Chiu,Y.H., Chiang,Y.C., Chen,C.H., Lee,T.H., Santella,R.M., Chern,H.D., Liaw,Y.F. and Chen,C.J. (1999) Plasma carotenoids, glutathione S-transferase M1 and T1 genetic polymorphisms and risk of hepatocellular carcinoma: independent and interactive effects. Am. J. Epidemiol., 149, 621-629.
    • (1999) Am. J. Epidemiol. , vol.149 , pp. 621-629
    • Yu, M.W.1    Chiu, Y.H.2    Chiang, Y.C.3    Chen, C.H.4    Lee, T.H.5    Santella, R.M.6    Chern, H.D.7    Liaw, Y.F.8    Chen, C.J.9
  • 11
    • 0034714521 scopus 로고    scopus 로고
    • Genotype analysis of the CYP2C19 gene in HCV-seropositive patients with cirrhosis and hepatocellular carcinoma
    • Chau,T.K., Marakami,S., Kawai,B., Nasu,K., Kubota,T. and Ohnishi,A. (2000) Genotype analysis of the CYP2C19 gene in HCV-seropositive patients with cirrhosis and hepatocellular carcinoma, Life Sci., 67, 1719-1724.
    • (2000) Life Sci. , vol.67 , pp. 1719-1724
    • Chau, T.K.1    Marakami, S.2    Kawai, B.3    Nasu, K.4    Kubota, T.5    Ohnishi, A.6
  • 12
    • 0034765595 scopus 로고    scopus 로고
    • Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene
    • Vogel,A., Kneip,S., Barut,A., Ehmer,U., Tukey,R.H., Manns,M.P. and Strassburg,C.P. (2001) Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene. Gastroenterology, 121, 1136-1144.
    • (2001) Gastroenterology , vol.121 , pp. 1136-1144
    • Vogel, A.1    Kneip, S.2    Barut, A.3    Ehmer, U.4    Tukey, R.H.5    Manns, M.P.6    Strassburg, C.P.7
  • 13
    • 0032979681 scopus 로고    scopus 로고
    • A p53 genetic polymorphism as a modulator of hepatocellular carcinoma risk in relation to chronic liver disease, familial tendency and cigarette smoking in hepatitis B carriers
    • Yu,M.W., Yang,S.Y., Chiu,Y.H., Chiang,Y.C., Liaw,Y.F. and Chen,C.J. (1999) A p53 genetic polymorphism as a modulator of hepatocellular carcinoma risk in relation to chronic liver disease, familial tendency and cigarette smoking in hepatitis B carriers. Hepatology, 29, 697-702.
    • (1999) Hepatology , vol.29 , pp. 697-702
    • Yu, M.W.1    Yang, S.Y.2    Chiu, Y.H.3    Chiang, Y.C.4    Liaw, Y.F.5    Chen, C.J.6
  • 17
    • 0033607241 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults
    • Skibola,C.F., Smith,M.T., Kane,E., Roman,E., Rollinson,S., Cartwright,R.A. and Morgan,G. (1999) Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. Proc. Natl Acad. Sci. USA, 96, 12810-12815.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 12810-12815
    • Skibola, C.F.1    Smith, M.T.2    Kane, E.3    Roman, E.4    Rollinson, S.5    Cartwright, R.A.6    Morgan, G.7
  • 18
    • 0035672957 scopus 로고    scopus 로고
    • The methylenetetrahydrofolate reductase C677T gene polymorphism decreases the risk of childhood acute lymphocytic leukaemia
    • Franco,R.F., Simoes,B.P., Tone,L.G., Gabellini,S.M., Zago,M.A. and Falcao,R.P. (2001) The methylenetetrahydrofolate reductase C677T gene polymorphism decreases the risk of childhood acute lymphocytic leukaemia. Br. J. Haematol., 115, 616-618.
    • (2001) Br. J. Haematol. , vol.115 , pp. 616-618
    • Franco, R.F.1    Simoes, B.P.2    Tone, L.G.3    Gabellini, S.M.4    Zago, M.A.5    Falcao, R.P.6
  • 19
    • 0031431662 scopus 로고    scopus 로고
    • Germ line polymorphisms in cytochrome-P450 1A1 (C4887 CYP1A1) and methylenetetrahydrofolate reductase (MTHFR) genes and endometrial cancer susceptibility
    • Esteller,M., Garcia,A., Martinez-Palones,J.M., Xercavins,J. and Reventos,J. (1997) Germ line polymorphisms in cytochrome-P450 1A1 (C4887 CYP1A1) and methylenetetrahydrofolate reductase (MTHFR) genes and endometrial cancer susceptibility. Carcinogenesis, 18, 2307-2311.
    • (1997) Carcinogenesis , vol.18 , pp. 2307-2311
    • Esteller, M.1    Garcia, A.2    Martinez-Palones, J.M.3    Xercavins, J.4    Reventos, J.5
  • 20
    • 0035870245 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population
    • Song,C., Xing,D., Tan,W., Wei,Q. and Lin,D. (2001) Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population. Cancer Res., 61, 3272-3275.
    • (2001) Cancer Res. , vol.61 , pp. 3272-3275
    • Song, C.1    Xing, D.2    Tan, W.3    Wei, Q.4    Lin, D.5
  • 21
    • 0036016321 scopus 로고    scopus 로고
    • Linkage disequilibrium between the 667C>T and 1298A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer
    • Chen,J., Ma,J., Stampfer,M.J., Palomeque,C., Selhub,J. and Hunter,D.J. (2002) Linkage disequilibrium between the 667C>T and 1298A>C polymorphisms in human methylenetetrahydrofolate reductase gene and their contributions to risk of colorectal cancer. Pharmacogenomics, 12, 339-342.
    • (2002) Pharmacogenomics , vol.12 , pp. 339-342
    • Chen, J.1    Ma, J.2    Stampfer, M.J.3    Palomeque, C.4    Selhub, J.5    Hunter, D.J.6
  • 23
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst,P., Blom,H.J., Milos,R. et al. (1995) A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nature Genet., 10, 111-113.
    • (1995) Nature Genet. , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 25
    • 0033970043 scopus 로고    scopus 로고
    • Folate and carcinogenesis: An integrated scheme
    • Choi,S.W. and Mason,J.B. (2000) Folate and carcinogenesis: an integrated scheme. J. Nutr., 130, 129-132.
    • (2000) J. Nutr. , vol.130 , pp. 129-132
    • Choi, S.W.1    Mason, J.B.2
  • 28
    • 0036757192 scopus 로고    scopus 로고
    • Rapid automated simultaneous screening of (G1691A) factor V, (G20210A) Prothrombin and (C677T) methylenetetrahydrofolate reductase variants by multiplex PCR using fluorescence scanning technology
    • Saffroy,R., Lemoine,A., Haas,P., Marion,S. and Debuire,B. (2002) Rapid automated simultaneous screening of (G1691A) factor V, (G20210A) Prothrombin and (C677T) methylenetetrahydrofolate reductase variants by multiplex PCR using fluorescence scanning technology. Genet Test., 6, 233-236.
    • (2002) Genet. Test. , vol.6 , pp. 233-236
    • Saffroy, R.1    Lemoine, A.2    Haas, P.3    Marion, S.4    Debuire, B.5
  • 29
    • 0033865333 scopus 로고    scopus 로고
    • Elevated homocysteine levels in alcohol withdrawal
    • Bleich,S., Degner,D., Wiltfang,J. et al. (2000) Elevated homocysteine levels in alcohol withdrawal. Alcohol Alcohol, 35, 351-354.
    • (2000) Alcohol Alcohol , vol.35 , pp. 351-354
    • Bleich, S.1    Degner, D.2    Wiltfang, J.3
  • 30
    • 0035676273 scopus 로고    scopus 로고
    • High prevalence of hyperhomocysteinemia in chronic alcoholism: The importance of the thermolabile form of the enzyme methylenetetrahydrofolate reductase (MTHFR)
    • de la Vega,M.J., Santolaria,F., Gonzalez-Reimers,E., Aleman,M.R., Milena,A., Martinez-Riera,A. and Gonzalez-Garcia,C. (2001) High prevalence of hyperhomocysteinemia in chronic alcoholism: the importance of the thermolabile form of the enzyme methylenetetrahydrofolate reductase (MTHFR). Alcohol, 25, 59-67.
    • (2001) Alcohol , vol.25 , pp. 59-67
    • de la Vega, M.J.1    Santolaria, F.2    Gonzalez-Reimers, E.3    Aleman, M.R.4    Milena, A.5    Martinez-Riera, A.6    Gonzalez-Garcia, C.7
  • 31
    • 0037102253 scopus 로고    scopus 로고
    • Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis
    • Machover,D., Zittoun,J., Saffroy,R. et al. (2002) Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis. Cancer Res., 62, 4685-4689.
    • (2002) Cancer Res. , vol.62 , pp. 4685-4689
    • Machover, D.1    Zittoun, J.2    Saffroy, R.3
  • 34
    • 0031816123 scopus 로고    scopus 로고
    • Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
    • Jacob,R.A., Gretz,D.M., Taylor,P.C., James,S.J., Pogribny,I.P., Miller,B.J., Henning,S.M. and Swendseid,M.E. (1998) Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women. J. Nutr., 128, 1204-1212.
    • (1998) J. Nutr. , vol.128 , pp. 1204-1212
    • Jacob, R.A.1    Gretz, D.M.2    Taylor, P.C.3    James, S.J.4    Pogribny, I.P.5    Miller, B.J.6    Henning, S.M.7    Swendseid, M.E.8
  • 35
    • 0026064347 scopus 로고
    • Repair of uracil residues closely spaced on the opposite strands of plasmid DNA results in double-strand break and deletion formation
    • Dianov,G.L., Timchenko,T.V., Sinitsina,O.I., Kuzminov,A.V., Medvedev,O.A. and Salganik,R.I. (1991) Repair of uracil residues closely spaced on the opposite strands of plasmid DNA results in double-strand break and deletion formation. Mol. Gen. Genet., 225, 448-452.
    • (1991) Mol. Gen. Genet. , vol.225 , pp. 448-452
    • Dianov, G.L.1    Timchenko, T.V.2    Sinitsina, O.I.3    Kuzminov, A.V.4    Medvedev, O.A.5    Salganik, R.I.6
  • 36
    • 0032530829 scopus 로고    scopus 로고
    • Chromosomal aberrations in lymphocytes predict human cancer: A report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH)
    • Hagmar,L., Bonassi,S., Stromberg,U., Brogger,A., Knudsen,L.E., Norppa,H. and Reuterwall,C. (1998) Chromosomal aberrations in lymphocytes predict human cancer: a report from the European Study Group on Cytogenetic Biomarkers and Health (ESCH). Cancer Res., 58, 4117-4121.
    • (1998) Cancer Res. , vol.58 , pp. 4117-4121
    • Hagmar, L.1    Bonassi, S.2    Stromberg, U.3    Brogger, A.4    Knudsen, L.E.5    Norppa, H.6    Reuterwall, C.7
  • 37
    • 0034653699 scopus 로고    scopus 로고
    • Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens
    • European Study Group on Cytogenetic Biomarkers and Health
    • Bonassi,S., Hagmar,L., Stromberg,U. et al. (2000) Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens. European Study Group on Cytogenetic Biomarkers and Health. Cancer Res., 60, 1619-1625.
    • (2000) Cancer Res. , vol.60 , pp. 1619-1625
    • Bonassi, S.1    Hagmar, L.2    Stromberg, U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.