RNA interference and its current application in mammals

Chinese Medical Journal

Volumn 117, Issue 7, 2004, Pages 1084-1091

  Shen, Wei Gan ^a,b   Li, Chao Jun ^a,b  

^a NANJING NORMAL UNIVERSITY   (China)

^b YANGZHOU UNIVERSITY   (China)

Author keywords

Double stranded RNA; Gene knock down; Mammalian; Post transcriptional gene silencing; RNA interference; Small interfering RNA; Therapeutics

Indexed keywords

BCR ABL PROTEIN; CALCIUM PHOSPHATE; CD4 ANTIGEN; DNA DIRECTED RNA POLYMERASE III; DOUBLE STRANDED DNA; INTERLEUKIN 12; LIPOSOME; MELANOMA ANTIGEN; MYOCYTE ENHANCER FACTOR 2; SMALL INTERFERING RNA; TRINUCLEOTIDE;

DNA VECTOR; ELECTROPORATION; EXPRESSION VECTOR; GENE DELIVERY SYSTEM; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE SILENCING; GENE TARGETING; GENE TECHNOLOGY; GENE THERAPY; GENETIC TRANSFECTION; GENETICS; HUMAN; MAMMAL CELL; MICROINJECTION; NONHUMAN; PUBLICATION; REVIEW; RNA INTERFERENCE;

ANIMALS; ANTIGENS, NEOPLASM; GENE SILENCING; GENE THERAPY; GENES, ABL; HUMANS; NEOPLASM PROTEINS; RNA INTERFERENCE;

EID: 4344681982     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (41)

1. Elbashir SM, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001;411:494-498.
2. Tuschl T, Zamore PD, Lehmann R, et al. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev 1999;13:3191-3197.
3. Vaucheret H, Beclin C, Fagard M. Post-transcriptional gene silencing in plants. J Cell Sci 2001;114:3083-3091.
4. Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998;391:806-811.
5. Paddison PJ, Candy AA, Bernstein E, et al. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev 2002;16:948-958.
6. Paddison PJ, Caudy AA, Hannon GJ. Stable suppression of gene expression by RNAi in mammalian cells. Proc Natl Acad Sci USA 2002;99:1443-1448.
7. Lee NS, Dohjima T, Bauer G, et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 2002;20:500-505.
8. Billy E, Brondani V, Zhang H, et al. Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines. Proc Natl Acad Sci USA 2001;98:14428-14433.
9. Yang S, Tutton S, Pierce E, et al. Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells. Mol Cell Biol 2001;21:7807-7816.
10. Donze O, Picard D. RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res 2002;30:e46.
11. McManus MT, Sharp PA. Gene silencing in mammalians by small interfering RNAs. Nat Rev Genet 2002;3:737-747.
12. Harborth J, Elbashir SM, Bechert K, et al. Identification of essential genes in cultured mammalian cells using small interfering RNAs. J Cell Sci 2001;114:4557-4565.
13. Gaudilliere B, Shi Y, Bonni A. RNA interference reveals a requirement for MEF2A in activity-dependent neuronal survival. J Biol Chem 2002;277:46442-46446.
14. Paul CP, Good PD, Winer I, et al. Effective expression of small interfering RNA in human cells. Nat Biotechnol 2002; 20:505-508.
15. Grosshans H, Slack FJ. Micro-RNAs: small is plentiful. J Cell Biol 2002;156:17-21.
16. Reinhart BJ, Bartel DP. Small RNAs correspond to centromere heterochromatic repeats. Science 2002;297:831.
17. Baulcombe D. DNA events. An RNA microcosm. Science 2002;297:2002-2003.
18. Zhou Y, Ching YP, Kok KH, et al. Post-transcriptional suppression of gene expression in xenopus embryos by small interfering RNA. Nucleic Acids Res 2002;30:1664-1669.
19. Nicholson RH, Nicholson AW. Molecular characterization of a mouse cDNA encoding Dicer, a ribonuclease III ortholog involved in RNA interference. Mamm Genome 2002;13:67-73.
20. Provost P, Dishart D, Doucet J, et al. Ribonuclease activity and RNA binding of recombinant human Dicer. EMBO J 2002;21:5864-5874.
21. Tuschl T. Expanding small RNA interference. Nat Biotechnol 2002;20:446-448.
22. Miyagishi M, Taira K. U6 promoter-driven siRNAs with four uridine 3′-overhangs efficiently suppress targeted gene expression in mammalian cells. Nat Biotechnol 2002;20:497-500.
23. Yant SR, Ehrhardt A, Mikkelsen JG, et al. Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo. Nat Biotechnol 2002;20:999-1005.
24. Shuey DJ, McCallus DE, Giordano T. RNAi: gene-silencing in therapeutic intervention. Drug Discov Today 2002;7:1041-1046.
25. Yu JY, DeRuiter SL, Turner DL. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 2002;99:6047-6052.
26. Sui G, Soohoo C, Affarel B, et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 2002;99:5515-5520.
27. Chang TS, Jeong W, Choi SY, et al. Regulation of peroxiredoxin I activity by Cdc2- mediated phosphorylation. J Biol Chem 2002;277:25370-25376.
28. Scadden AD, Smith CW. RNAi is antagonized by A → I hyper-editing. EMBO Rep 2001;2:1107-1111.
29. Wilda M, Fuchs U, Wossmann W, et al. Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene 2002;21:5716-5724.
30. Caplen NJ, Taylor JP, Statham VS, et al. Rescue of polyglutamine- mediated cytotoxicity by double-stranded RNA-mediated RNA interference. Hum Mol Genet 2002;11:175-184.
31. Muda M, Worby CA, Simonson-Leff N, et al. Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases. Biochem J 2002;366:73-77.
32. Silva JM, Hammond SM, Hannon GJ. RNA interference: a promising approach to antiviral therapy? Trends Mol Med 2002;8:505-518.
33. Jacque JM, Triques K, Stevenson M. Modulation of HIV-1 replication by RNA interference. Nature 2002;418:435-438.
34. Capodici J, Kariko K, Weissman D. Inhibition of HIV-1 infection by small interferring RNA-mediated RNA Interference. J Immunol 2002;169:5196-5201.
35. Novina CD, Murray MF, Dykxhoorn DM, et al. siRNA-directed inhibition of HIV-1 infection. Nat Med 2002;8:681-686.
36. McCaffrey AP, Meuse L, Pham TT, et al. RNA interference in adult mice. Nature 2002;418:38-39.
37. Winston WM, Molodowitch C, Hunter CP. Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science 2002;295:2456-2459.
38. Sijen T, Fleenor J, Simmer F, et al. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 2001; 107:465-476.
39. Lipardi C, Wei Q, Paterson BM. RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs. Cell 2001;107:297-307.
40. Krichevsky AM, Kosik KS. RNAi functions in cultured mammalian neurons. Proc Natl Acad Sci USA 2002;99:11926-11929.
41. Stewart SA, Dykxhoorn DM, Palliser D, et al. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 2003;9:493-501.