Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I

Nucleic Acids Research

Volumn 32, Issue 15, 2004, Pages 4657-4664

  Rideout, Marc C ^a   Raymond, Amy C ^a,b   Burgin Jr , Alex B ^a,b  

^a DeCODE Chemistry & Biostructures   (United States)

^b SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DOUBLE STRANDED DNA; HYMECROMONE; NEW DRUG; NUCLEOTIDE; OLIGONUCLEOTIDE; PHOSPHATE; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PHOSPHOTYROSINE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SINGLE STRANDED DNA; TYROSINE; TYROSYL DNA PHOSPHODIESTERASE I; UMBELLIFERONE DERIVATIVE; UNCLASSIFIED DRUG; VANADIC ACID; 4-METHYLUMBELLIFERONE; DRUG DERIVATIVE; FLUORESCENT DYE; TDP1 PROTEIN, HUMAN; TYROSYL DNA PHOSPHODIESTERASE; TYROSYL-DNA PHOSPHODIESTERASE;

ARTICLE; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME DEGRADATION; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SYNTHESIS; FLUORESCENCE ANALYSIS; HIGH THROUGHPUT SCREENING; HUMAN; INTERMETHOD COMPARISON; MAMMAL CELL; PRIORITY JOURNAL; REPORTER GENE; SENSITIVITY ANALYSIS; SPINOCEREBELLAR DEGENERATION; STEADY STATE; VALIDATION PROCESS; CHEMISTRY; KINETICS; METABOLISM; SPECTROFLUOROMETRY; SYNTHESIS;

MAMMALIA;

FLUORESCENT DYES; HUMANS; HYMECROMONE; KINETICS; OLIGONUCLEOTIDES; PHOSPHORIC DIESTER HYDROLASES; SPECTROMETRY, FLUORESCENCE;

EID: 4344587481     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh796     Document Type: Article

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