Characterization of the MODY3 phenotype. Early-onset diabetes caused by an insulin secretion defect

Journal of Clinical Investigation

Volumn 99, Issue 4, 1997, Pages 582-591

  Lehto, Markku ^a,i   Tuomi, Tiinamaija ^a   Mahtani, Melanie M ^b   Widén, Elisabeth ^b   Forsblom, Carol ^c   Sarelin, Leena ^e   Gullström, Monika ^f   Isomaa, Bo ^e   Lehtovirta, Mikko ^c   Hyrkkö, Auli ^c   Kanninen, Timo ^a   Orho, Marju ^a   Manley, Sue ^h   Turner, Robert C ^h   Brettin, Thomas ^b   Kirby, Andrew ^b   Thomas, Jeffrey ^d   Duyk, Geoffrey ^d   Lander, Eric ^b,g   Taskinen, Marja Riitta ^c   Groop, Leif ^a   more..

^a LUND UNIVERSITY   (Sweden)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d MILLENNIUM PHARMACEUTICALS INC   (United States)

^e Jakobstad Primary Care Center   (Finland)

^f Närpes Primary Care Center   (Finland)

^g MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^h UNIVERSITY OF OXFORD   (United Kingdom)

ⁱ Department of Endocrinology   (Sweden)

Author keywords

genetics; insulin deficiency; insulin sensitivity; maturity onset diabetes of the young; non insulin dependent diabetes mellitus

Indexed keywords

ADULT; AGED; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CHROMOSOME 12Q; FEMALE; GENE LOCUS; GENE MUTATION; GENETIC LINKAGE; HUMAN; INSULIN DEFICIENCY; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PENETRANCE; PHENOTYPE; PRIORITY JOURNAL;

EID: 0031027502     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119199     Document Type: Article

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