Stimulation of fibroblast growth factor receptor-1 occupancy and signaling by cell surface-associated syndecans and glypican

Journal of Cell Biology

Volumn 133, Issue 2, 1996, Pages 405-416

  Steinfeld, Robert ^a   Van Den Berghe, Herman ^a   David, Guido ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b CENTER FOR HUMAN GENETICS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; GLYCOPHORIN A; GLYPICAN; HEPARIN; PROTEOGLYCAN; SYNDECAN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN K 562; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CROSS LINKING; RECEPTOR BINDING; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION;

ANTIGENS, CD14; BASE SEQUENCE; CELL DIFFERENTIATION; CROSS-LINKING REAGENTS; FIBROBLAST GROWTH FACTOR 2; GLYCOPHORIN; GLYCOSAMINOGLYCANS; HEMATOPOIETIC STEM CELLS; HEPARAN SULFATE PROTEOGLYCANS; HEPARIN; HEPARITIN SULFATE; HUMANS; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEOGLYCANS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTORS, FIBROBLAST GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0029878968     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.133.2.405     Document Type: Article

References (54)

1. Armstrong, E , S. Vamikka, J Partanen, J. Korhonen, and R. Alitalo. 1992. Expression of fibroblast growth factor receptors in human leukemia cells. Cancer Res. 52:2004-2007
2. Aviezer, D., E. Levy, M. Safran, C Svahn, E. Buddecke, A. Schmidt, G David, I. Vlodavsky, and A. Yayon. 1994a Differential structural requirements of heparin and heparan sulfate proteoglycans that promote binding of basic fibroblast growth factor to its receptor. J. Biol. Chem. 269:114-121.
3. Aviezer, D., D. Hecht, M. Safran, M. Eisinger, G. David, and A Yayon 1994b Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis. Cell 79 1005-1013.
4. Bergonzoni, L , P. Caccia, O. Cletini, P. Sarmientos, and A. Isacchi. 1992. Characterization of a biologically active extracellular domain of fibroblast growth factor receptor 1 expressed in Eschericlua coli. Eur. J. Biochem. 210:823-829.
5. Chellaiah, A.T., D.G. McEwen, S. Werner, J. Xu, and D.M. Ornitz. 1994. Fibroblast growth factor receptor (FGFR) 3 Alternative splicing in immunoglobulin-like domain III creates a receptor hitihly specific for acidic FGF/FGF-1. J. Biol Chem 269:11620-11627.
6. David, G., V Lories, B Decock, P Marynen, J -J. Cassiman. and H. van den Berghe. 1990. Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts. J. Cell Biol 111:3165-3176
7. David, G , X.M. Bai, B van der Schueren, J.-J. Cassiman, and H van den Berghe. 1992a. Developmental changes in heparan sulfate expression. in situ detection with monoclonal antibodies. J. Cell Biol. 119:961-975.
8. David, G., B. van der Schueren, P. Marynen. J.-J. Cassiman, and H. van den Berghe. 1992b. Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells J Cell Biol. 118.961-969.
9. Dionne, C.A., G. Crumley, F. Bellot, J.M. Kaplow, G. Searfoss, M. Ruta, W H. Burgess, M. Jaye, and J. Schlessinger. 1990. Cloning and expression of two distinct high-affinity receptors cross reacting with acidic and basic fibroblast growth factors. EMBO (Eur. Mol Biol. Organ.) J. 9:2685-2692.
10. Eisemann, A., J A. Ahn, G Graziani, S.R. Tronick, and D. Ron. 1991 Alternative splicing generates at least five different isoforms of the human basic-FGF receptor. Oncogene. 6:1195-1202.
11. Guimond, S., M. Maccarana, B.B. Olwin, U. Lindahl, and A.C. Rapraeger 1993. Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4. J Biol Chem. 268: 23906-23914.
12. Habuchi, H., S. Suzuki, T. Saito, T. Tamura, T. Harada, K. Yoshida, and K. Kimata. 1992. Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor Biochem J. 285.805-813
13. Hochuli, E., H Döbeli, and A. Schacher 1987 New metal chelate adsorbant selective for proteins and peptide containing neighboring histidine residues. J Chromatogr. 411 177-184.
14. Honma, Y., J. Okabe-Kado, M. Hozumi, Y Uehara, and S Mizumi. 1989. Induction of erythroid differentiation of K562 human leukemic cells by herbimycin A, an inhibitor of tyrosine kinase activity. Cancer Res. 49.331-334.
15. Ishihara, M , D J. Tyrrell, G.B Stauber, S. Brown, L.S Cousens. and R.J. Stack. 1993. Preparation of affinity-fractionated, heparin-derived oligosaccharides and their effects on selected biological activities mediated by basic fibroblast growth factor. J Biol. Chem. 268:4675-4683
16. Johnson, D.E. J Lu, H. Chen, S. Werner, and L.T. Williams. 1991. The human fibroblast growth factor receptor genes. a common structural arrangement underlies the mechanism for generating receptor forms that differ in their third immunoglobulin domain. Mol Cell Biol 11 4627-4634.
17. Kan, M., F Wang, J Xu. J.W. Crabb, J. Hou, and W.L McKeehan 1993. An essential heparin-binding domain in the fibroblast growth factor receptor kinase. Science (Wash. DC). 259:1918-1921.
18. Kato, M., H. Wang, M. Bernfield, J.T. Gallagher, and J.E. Turnbull. 1994. Cell surface syndecan-1 on distinct cell types differs in fine structure and ligand binding of its heparan sulfate chains. J. Biol. Chem 269 18881-18890.
19. Keegan, K., D.E Johnson, L.T. Williams, and M.J. Hayman. 1991. Isolation of an additional member of the fibroblast growth factor receptor family. FGFR-3. Proc Natl. Acad. Sci. USA. 88:1095-1099
20. Kiefer, M.C., A. Baird, T. Nguyen, C. Gcorgc-Nascimcnto, O.B. Mason, L.J. Boley, P. Valenzuela, and P.J Barr. 1991. Molecular cloning of a human basic fibroblast growth factor receptor cDNA and expression of a biologically active extracellular domain in a baculovirus system. Growth Factors 5:115-127.
21. Lories, V., J.-J. Cassiman, H. van den Berghe, and G. David. 1989. Multiple distinct membrane heparan sulfate proteoglycans in human lung fibroblasts. J. Biol. Chem. 264:7009-7016.
22. Lories, V., H. De Boeck, G. David, J.-J. Cassiman, and H. van den Berghe. 1987. Heparan sulfate proteoglycans of human lung fibroblasts. J Biol Chem. 262:854-859.
23. Maccarana, M., B. Casu, and U. Lindahl. 1993. Minimal sequence in heparin/ heparan sulfate required for binding of basic fibroblast growth factor J. Biol. Chem. 268:23898-23905.
24. Mali, M , K. Elenius, H M Miettinen, and M. Jalkanen. 1993. Inhibition of basic fibroblast growth factor-induced growth promotion by overexpression of syndecan-1. J. Biol. Chem. 268:24215-24222.
25. Mali, M., P. Jaakkola, A.-M Arvilommi, and M. Jalkanen. 1990. Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans. J. Biol. Chem. 265:6884-6889.
26. Marynen, P., J. Zhang, J -J. Cassiman, H van den Berghe, and G. David 1989. Partial primary structure of the 48- and 90-kilodalton core proteins of cell surface-associated heparan sulfate proteoglycans of lung fibroblasts. J. Biol. Chem. 264:7017-7024.
27. Mason, I J. 1994. The ins and outs of fibroblast growth factors. Cell 78:547-552.
28. Metz, C N, G. Brunner, N H. Choi-Muira, H. Nguyen, J. Gabnlove, I W. Caras, N. Altszuler, D.B Rifkin, E L. Wilson, and M.A. Davitz. 1994 Release of GPI-anchored membrane proteins by a cell-associated GPI-specific phospholipase D EMBO (Eur. Mol. Biol. Organ ) J. 13:1741-1751.
29. Miki, T.. D.P. Bottaro, T.P. Fleming, C.L. Smith, W.H. Burgess, A.M. Chan, and S.A. Aaronson. 1992 Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc Natl. Acad. Sci. USA 89:246-250.
30. Moscatelli, D. 1987. High and low affinity binding sites for basic fibroblast growth factor on cultured cells: absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells. J. Cell. Physiol. 131:123-130.
31. Nugent, M.A.. and E.R. Edelman. 1992. Kinetics of basic fibroblast growth factor to its receptor and heparan sulfate proteoglycan: a mechanism for cooperativity. Biochemistry 31:8876-8883.
32. Nurcombe, V., M D. Ford, J.A. Wildschut, and P.F Bartlett. 1993. Developmental regulation of neural response to FGF-1 and FGF-2 by heparan sulfate proteoglycan Science (Wash. DC). 260:103-106.
33. Ornitz, D.M., A. Yayon, J G. Flanagan, C.M. Svahn, E. Levi, and P. Leder. 1992. Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Mol. Cell. Biol 12:240-247.
34. Pantohano, M.W , R.A Horlick, B.A. Springer, D.E. Van Dyk, T. Tobery, D R. Wetmore, J.D. Lear, A.T. Nahapetian, J D. Bradley, and W P. Sisk, 1994 Multivalent ligand-receptor binding interactions in the fibroblast growth factor system produce a cooperative growth factor and heparin mechanism for receptor dimerization. Biochemistry. 33:10229-10248.
35. Papayannopoulou, T., B Nakamoto, T Yokochi, A Chait, and R. Kannagi. 1983. Human erythroleukemia cell line (HEL) undergoes a macrophage-like shift with TPA. Blood. 62:832-845.
36. Partanen, J., T.P. Makelä, E. Eerola, J. Korhoncn, H. Hirvonen, L. Claesson-Welsh, and K. Alitalo. 1991. FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO (Eur. Mol Biol. Organ ) J 10:1347-1354.
37. Rapraeger, A.C., A. Krufka, and B.B. Olwin. 1991. Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation. Science (Wash DC). 252:1705-1708
38. Richardson, J.M., A.O. Morla, and J Y.J. Wang. 1987. Reduction in protein tyrosinc phosphorylation during differentiation of human leukemia cell line K562. Cancer Res 47.4066-4070.
39. Roghani, M , A. Mansukhani, P. Dell'Era, P. Bellosta, C. Basilico, D.B Rifkin, and D. Moscatelli. 1994. Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding. J Biol Chem 269:3976-3984.
40. Saiki, R.K , D.H. Gelfand, S. Stoffel, S J. Scharf, R Higuchi, G. T. Horn, K.B. Mullis, and H.A. Ehrlich 1988. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science (Wash DC). 239:487-491.
41. Sambrook, J., E F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
42. Scatchard, G. 1949. The attractions of proteins for small molecules and ions. Ann NY Acad. Sci. 51:660-672.
43. Schagger, H., and G. von Jagow. 1987. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 166 368-379.
44. Seno, M., R Sasada, T. Kurokawa, and K. Igarashi. 1990. Carboxyl-terminal structure of basic fibroblast growth factor significantly contributes to its affinity for heparin. Eur. J. Biochem. 188:239-245.
45. Shively, I.E., and H.E Conrad. 1976. Formation of anhydrosugars in the chemical depolymerization of heparin. Biochemistry. 15:3932-3942
46. Shworak, N.W., M. Shirakawa, S. Colliec-Jouault, J. Liu, R.C. Mulligan, L.K. Birinyi, and R.D. Rosenberg. 1994. Pathway-specific regulation of the synthesis of anticoagulantly active heparan sulfate. J. Biol. Chem. 269:24941-24952.
47. Spivak-Kroizman, T., M.A. Lemmon, I. Dikic, J.E. Ladbury, D. Pinchasi, J. Huang, M. Jaye, G. Crumley, J. Schlessinger, and I Lax 1994. Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization. activation, and cell proliferation. Cell 79.1015-1024.
48. Turnbull, J.E., D.G. Fernig, Y Ke, M C. Wilkinson, and J.T. Gallagher. 1992 Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate. J. Biol. Chem. 267:10337-10341.
49. Tyrrell, D.J., M. Ishihara, N. Rao, A. Horne, M C. Kiefer, G. B Stauber, L.H. Lam, and R.J. Stack. 1993. Structure and biological activities of a heparinderived hexasaccharide with high affinity for basic fibroblast growth factor J. Biol. Chem. 268:4684-4689.
50. Walker, A., J.E. Turnbull, and J.T Gallagher. 1994. Specific heparan sulfate saccharides mediate the activity of basic fibroblast growth factor. J. Biol Chem. 269:931-935.
51. Wennström, S., C. Sandström, and L. Claesson-Welsh. 1991 cDNA cloning and expression of a human FGF receptor which binds acidic and basic FGF Growth Factors. 4:197-208.
52. Werner, S., D.S. Duan, C. de Vries, K.G. Peters, D.E. Johnson, and L. T. Williams 1992. Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities. Mol. Cell. Biol. 12:82-88.
53. Yayon, A., M Klagsbrun, J.D. Esko, P. Leder, and D.M Ornitz 1991. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell. 64:841-848
54. Yayon, A., Y. Zimmer, G.H. Shen, A. Avivi, Y. Yarden, and D. Givol. 1992. A confined variable region confers ligand specificity on fibroblast growth factor receptors: implications for the origin of the immunoglobulin fold. EMB (Eur. Mol. Biol. Organ ) J 11:1885-1890.