Gpc3 expression correlates with the phenotype of the Simpson-Golabi- Behmel syndrome

Developmental Dynamics

Volumn 213, Issue 4, 1998, Pages 431-439

  Pellegrini, Massimo ^a,f   Pilia, Giuseppe ^b,c   Pantano, Serafino ^a   Lucchini, Franco ^d   Uda, Manuela ^b,c   Fumi, Mariapaola ^d   Cao, Antonio ^b,c   Schlessinger, David ^e   Forabosco, Antonino ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b Centro Nazionale delle Ricerche   (Italy)

^c UNIVERSITY OF CAGLIARI   (Italy)

^d UNIVERSITÀ CATTOLICA DEL SACRO CUORE   (Italy)

^e NATIONAL INSTITUTE ON AGING   (United States)

^f Sezione di Istol Embriol e Genet   (Italy)

Author keywords

Gene expression; Glypican 3; Glypican related integral membrane heparan sulfate proteoglycans; Gpc3; In situ hybridization; Mouse; Simpson Golabi Behmel syndrome

Indexed keywords

COMPLEMENTARY DNA; GLYPICAN; GLYPICAN 3; MEMBRANE PROTEIN; SOMATOMEDIN B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BECKWITH WIEDEMANN SYNDROME; EMBRYO; FETUS DEVELOPMENT; GROWTH REGULATION; HUMAN; HUMAN CELL; MEMBRANE MODEL; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; SIMPSON GOLABI BEHMEL SYNDROME; SYNDROME DELINEATION;

ABNORMALITIES, MULTIPLE; ANIMALS; BLOTTING, NORTHERN; ECTODERM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GIGANTISM; GLYPICANS; HEPARAN SULFATE PROTEOGLYCANS; HEPARITIN SULFATE; HUMANS; IN SITU HYBRIDIZATION; MESODERM; MICE; PHENOTYPE; PROTEOGLYCANS; SYNDROME;

EID: 0031730116     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(199812)213:4<431::AID-AJA8>3.0.CO;2-7     Document Type: Article

References (29)

1. Ayer-Le Lievre C, Stahlbom RA, Sara VR. 1991. Expression of IGF-I and -II mRNA in the brain and craniofacial region of the rat fetus. Development 111:105-115.
2. Baker J, Liu J-P, Robertson EJ, Efstratiadis A. 1993. Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75: 73-82.
3. Beck F, Samani NJ, Penschow JD, Thorley B, Tregear GW, Coghlan JP. 1987. Histochemical localization of IGF-I and -II mRNA in the developing rat embryo. Development 101:175-184.
4. Bondy CA, Werner H, Roberts, CT Jr, LeRoith D. 1990. Cellular pattern of insulin like growth factor-1 (IGF-1) and type I IGF receptor gene expression in early organogenesis: Comparison with IGF-II gene expression. Mol Endocrinol 4:1386-1398.
5. Cross M, Dexter TM. 1991. Growth factors in development, transformation, and tumorigenesis. Cell 64:271-280.
6. David G. 1993. Integral membrane heparan sulfate proteoglycans. FASEB J 7:1023-1030.
7. Garganta CL, Bodurtha JN. 1992. Report of another family with Simpson-Golabi-Behmel syndrome and a review of the literature. Am J Med Genet 44:129-135.
8. Haig D, Graham C. 1991. Genomic imprinting in the strange case of the insulin-like growth factor ii receptor. Cell 64:1045-1046.
9. Lahm H, Amstad P. Wyniger J, Yilmaz A, Fischer JR, Schreyer M, Givel JC. 1994. Blockade of the insulin-like growth factor-1 receptor inhibits growth of human colorectal cancer cells: Evidence of a functional IGF-II-mediated autocrine loop. Int J Cancer 58:452-459
10. Lau MMH, Stewart CEH, Liu Z, Bhatt H, Rotwein P, Stewart CL. 1994. Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality. Genes Dev 8:2953-2963.
11. Lee JE, Pintar J, Efstratiadis A. 1990. Pattern of insulin-like growth factor II gene expression during early mouse embryogenesis. Development 110:151-159.
12. Leighton PA, Ingram RS, Eggenschwiler J, Efstratiadis A, Tilghman SM. 1995. Disruption of imprinting caused by deletion of the H19 gene region in mice. Nature 375:34-39.
13. Liu J-P, Baker J, Perkins AS, Robertson EJ, Efstratiadis A. 1993. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-I) and type 1 IGF receptor (Igf1r). Cell 75:59-72.
14. Louvi A, Accili D, Efstratiadis A. 1997. Growth-promoting interaction if IGF-II with the insulin receptor during mouse embryonic development. Dev Biol 189:33-48.
15. Lui VCH, Ng LJ, Nicholls J, Tam PPT, and Cheah, KSE. 1995. Tissue-specific and differential expression of alternatively spliced 1(II) collagen mRNAs in early human embryos. Dev Dyn 203:198-211.
16. Matzner U, Von Figura K, Pohlmann R. 1992. Expression of the two mannose 6-phosphate receptors is spatially and temporally different during mouse embryogenesis. Development 114:965-972.
17. Matzner U, Hille-Rehfeld A, Von Figura K, Pohlmann R. 1996. Expression of Mannose 6-phosphate receptors in chicken. Dev Dyn 207:11-24.
18. Morgan DO, Edman JC, Standring DN, Fried VA, Smith MC, Roth RA, and Rutter W.J. 1987. Insulin-like growth factor II receptor as a multifunctional binding protein. Nature 329:301-307.
19. Ogawa O, Becroft DM, Morison IM, Eccles MR, Skeen JE, Mauger DC, Reeve AE. 1993. Constitutional relaxation of insulin-like growth factor II gene imprinting associated with Wilms' tumour and gigantism. Nat Genet 5:408-412.
20. Pilia G, Hughes-Benzie RM, MacKenzie A, Baybayan P, Chen EY, Huber R, Neri G, Cao A, Forabosco A, Schlessinger D. 1996. Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat Genet 12:241-247.
21. Raff CM. 1996. Size control: The regulation of cell numbers in animal development. Cell 86:173-175.
22. Retsch-Bogart GZ, Moats-Staats BM, Howard K, D'Ercole AJ, Stiles AD. 1996. Cellular localization of messenger RNAs for insulin-like growth factors (IGFs), their receptors and binding proteins during fetal rat lung development. Am J Respir Cell Mol Biol 14:61-69.
23. Schlessinger J, Lax I, Lemmon M. 1995. Regulation of growth factor activation by proteoglycans: What is the role of the low affinity receptors? Cell 83:357-360.
24. Senior PV, Byrne S, Brammar WJ, Beck F. 1990. Expression of the IGF-II/mannose-6-phosphate receptor mRNA and protein in the developing rat. Development 109:67-73.
25. Stylianopoulou F, Efstratiadis A, Herbert J, Pintar J. 1988. Pattern of the insulin-like growth factor II gene expression during rat embryogenesis. Development 103:497-506.
26. Sun F-L, Dean WL, Kelsey G, Allen ND, Reik W. 1997. Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome. Nature 389:809-815.
27. Thorogood P, Bee J, Von der Mark K. 1986. Transient expression of collagen type II at epitheliomesenchymal interfaces during morphogenesis of the cartilaginous neurocranium. Dev Biol 116:497-509.
28. Wang Z-Q, Furg MR, Barlow DP, Wagner EF. 1994. Regulation of embryonic growth and lysosomal targeting by the imprinted IgfII/ Mpr gene. Nature 372:464-467.
29. Wilkinson DG, Nieto MA. 1993. Detection of messenger RNAby in situ hybridization to tissue sections and whole mounts. Methods Enzymol 225:361-373.