OCI-5/GPC3, a glypican encoded by a gene that is mutated in the Simpson- Golabi-Behmel overgrowth syndrome, induces apoptosis in a cell line-specific manner

Journal of Cell Biology

Volumn 141, Issue 6, 1998, Pages 1407-1414

  Gonzalez, Alfonso Dueñas ^a,b   Kaya, Mitsunori ^a,b   Shi, Wen ^a,b   Song, Howard ^a,b   Testa, Joseph R ^c   Penn, Linda Z ^b,d   Filmus, Jorge ^a,b  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c FOX CHASE CANCER CENTER   (United States)

^d PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL; GLYPICAN; GLYPICAN 3; PROTEOHEPARAN SULFATE; SOMATOMEDIN B; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BECKWITH WIEDEMANN SYNDROME; BONE MALFORMATION; BREAST CARCINOMA; CONTROLLED STUDY; GENE MUTATION; GROWTH DISORDER; HUMAN; HUMAN CELL; MALFORMATION SYNDROME; MESOTHELIOMA; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; SIMPSON GOLABI BEHMEL OVERGROWTH SYNDROME; VISCERAL PAIN; X CHROMOSOME LINKED DISORDER;

3T3 CELLS; ANIMALS; APOPTOSIS; COS CELLS; GENE EXPRESSION; GLYCOSYLPHOSPHATIDYLINOSITOLS; GLYPICANS; GROWTH DISORDERS; HEPARAN SULFATE PROTEOGLYCANS; HT29 CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR II; MEMBRANE PROTEINS; MESOTHELIOMA; MICE; RATS; SYNDROME; TUMOR CELLS, CULTURED;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS;

EID: 0032526939     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.141.6.1407     Document Type: Article

References (41)

1. Baker, S.J., S. Markowitz, E.R. Fearon, J.K.V. Willson, and B. Vogelstein. 1990. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science. 249:912-915.
2. Bonneh-Barkay, D., M. Shlissel, B. Berman, E. Shaoul, A. Admon, I. Vlodavsky, D.J. Carey, V.K. Asundi, R. Reich-Slotky, and D. Ron. 1997. Identification of glypican as a dual modulator of the biological activity of fibroblast growth factors. J. Biol. Chem. 272:12415-12421.
3. Brodsky, R.A., M.S. Vala, J.P. Barber, M.E. Medof, and R.J. Jones. 1997. Resistance to apoptosis caused by PIG-A gene mutations in paroxysmal nocturnal hemoglobinuria. Proc. Natl. Acad. Sci. USA. 94:8756-8760.
4. Cadwell, R.C., and G.F. Joyce. 1995. Mutagenesis by PCR. In PCR Primer, a Laboratory Manual. C.W. Dieffenbach and G.S. Dveksler, editors. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 581-613.
5. Carey, D.J., and D.M. Evans. 1989. Membrane anchoring of heparan sulfate proteoglycans by phosphatidylinositol and kinetics of synthesis of peripheral and detergent-solubilized proteoglycans in Schwann cells. J. Cell Biol. 108: 1891-1897.
6. Chinnaiyan, A.M., K. O'Rourke, M. Tewari, and V.M. Dixit. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell. 81:505-512.
7. David, G. 1993. Integral membrane heparan sulfate proteoglycans. FASEB (Fed. Am. Soc. Exp. Biol.) J. 7:1023-1030.
8. David, G., V. Lories, B. Decock, P. Marynen, J. Cassiman, and H. Van Den Berghe. 1990. Molecular cloning of a phosphatidylinositol-anchorcd membrane heparan sulfate proteoglycan from human lung fibroblasts. J. Cell Biol. 111:3165-3176.
9. Eggenschwiler, J., T. Ludwig, P. Fisher, P.A. Leighton, S.M. Tilghman, and A. Efstratiadis. 1997. Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes. Genes Dev. 11:3128-3142.
10. Filmus, J., J. Church, and R.N. Buick. 1988. Isolation of a cDNA corresponding to a developmentally regulated transcript in rat intestine. Mol. Cell. Biol. 8:4243-4249.
11. Filmus, J., A.I. Robles, W. Shi, M.J. Wong, L.L. Colombo, and C.J. Conti. 1994. Induction of cyclin D1 overexpression by activated ras. Oncogene. 9:3627-3633.
12. Filmus, J., W. Shi, Z.M. Wong, and M.J. Wong. 1995. Identification of a new membrane-bound heparan sulfate proteoglycan. Biochem. J. 311:561-565.
13. Garganta, C.L., and J.N. Bodurtha. 1992. Report of another family with Simpson-Golabi-Behmel syndrome and a review of the literature. Am. J. Med. Genet. 44:129-135.
14. Gossen, M., A.L. Bonin, and H. Bujard. 1993. Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements. Trends Biol. Sci. 18:471-415.
15. Guillonneau, X., F. Regnier-Ricard, C. Dupuis, Y. Courtois, and F. Mascarelli. 1997. FGF2-stimulated release of endogenous FGF1 is associated with reduced apoptosis in retinal pigmented epithelial cells. Exp. Cell Res. 233:198-206.
16. Gurrieri, F., M. Cappa, and G. Neri. 1992. Further delineation of the Simpson-Golabi-Behmel (SGB) syndrome. Am. J. Med. Genet. 44:136-137.
17. Hague, A., D.J. Hicks, T.S. Bracey, and C. Paraskeva. 1997. Cell-cell contact and specific cytokines inhibit apoptosis of colonic epithelial cells: growth factors protect against c-myc-independent apoptosis. Br. J. Cancer. 75:960-968.
18. Harrington, E.A., M.R. Bennett, A. Fanidi, and G.I. Evan. 1994. c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO (Eur. Mol. Biol. Organ.) J. 13:3286-3295.
19. Hughes-Benzie, R.M., A.G.W. Hunter, J.E. Allanson, and A.E. Mackenzie. 1992. Simson-Golahi-Behmel syndrome associated with renal dysplasia and embryonal tumor: localization of the gene to Xqcen-q21. Am. J. Med. Genet. 43:428-435.
20. Hughes-Benzie, R.M., G. Pilia, J.Y. Xuan, A.G.W. Hunter, E. Chen, M. Golabi, J.A. Hurst, J. Kobori, K. Marymee, R.A. Pagon, et al. 1996. Simpson-Golabi-Behmel Syndrome: genotype/phenotype analysis of 18 affected males from 7 unrelated families. Am. J. Med. Genet. 66:227-234.
21. Jackson, S.M., H. Nakato, M. Sugiura, A. Jannuzi, R. Oakes, V. Kaluza, C. Golden, and S.B. Selleck. 1997. dally, a Drosophila glypican, controls cellular responses to the TGF-β-related morphogen Dpp. Development (Camb.). 124:4113-4120.
22. Jacobson, M.D., M. Weil, and M.C. Raff. 1997. Programmed cell death in animal development. Cell. 88:347-354.
23. Lin, J., C. Reichner, X. Wu, and A.J. Levine. 1996. Analysis of wild-type and mutant p21WAF-1 gene activities. Mol. Cell. Biol. 16:1786-1793.
24. Mizushima, S., and S. Nagata. 1990. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18:5322.
25. Muzio, M., A.M. Chinnaiyan, F.C. Kischkel, K. O'Rourke, A. Shevchenko, J. Ni, C. Scaffidi, J.D. Bretz, M. Zhang, R. Gentz, et al. 1996. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell. 85:817-827.
26. Nakato, H., T.A. Futch, and S.B. Selleck. 1995. The division abnormally delayed (dally) gene: a putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila. Development (Camb.). 121:3687-3702.
27. Pilia, G., R.M. Hughes-Benzie, A. MacKenzie, P. Baybayan, E.Y. Chen, R. Huber, G. Neri, A. Cao, A. Forabosco, and D. Schlessinger. 1996. Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat. Genet. 12:241-247.
28. Polyak, K., T. Waldman, T.C. He, K.W. Kinzler, and B. Vogelstein. 1996. Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev. 10:1945-1952.
29. Rapraeger, A.C., S. Guimond, A. Krufka, and B.B. Olwin. 1994. Regulation by heparan sulfate in fibroblast growth factor signaling. Methods Enzymol. 245: 219-240.
30. Rodeck, U., M. Jost, C. Kari, D.T. Shih, R.M. Lavker, D.L. Ewert, and P.J. Jensen. 1997. EGF-R dependent regulation of keratinocyte survival. J. Cell Sci. 110:113-121.
31. Salmivirta, M., K. Lidholt, and U. Lindahl. 1996. Heparan sulfate: a piece of information. FASEB (Fed. Am. Soc. Exp. Biol.) J. 10:1270-1279.
32. Saunders, S., S. Paine-Saunders, and A.D. Lander. 1997. Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain. Dev. Biol. 190:78-93.
33. Song, H.H., W. Shi, and J. Filmus. 1997. OCI-5/rat glypican-3 hinds to fibroblast growth factor-2 but not to insulin-like growth factor-2. J. Biol. Chem. 272: 7574-7577.
34. Steinfeld, R., H. Van Den Berghe, and G. David. 1996. Stimulation of fibroblast growth factor receptor-1 occupancy, and signaling by cell surface-associated syndecans and glypican. J. Cell Biol. 133:405-416.
35. Stipp, C.S., E.D. Litwac, and A.D. Lander. 1994. Cerebroglycan: an integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation. J. Cell Biol. 124:149-160.
36. Terespolsky, D., S.A. Farrell, J. Siegel-Bartelt, and R. Weksberg. 1995. Infantile lethal variant of Simpson-Golabi-Behmel syndrome associated with hydrops fetalis. Am. J. Med. Genet. 59:329-333.
37. Verloes, A., B. Massart, I. Dehalleux, J.P. Langhendries, and L. Koulischer. 1995. Clinical overlap of Beckwith-Wiedemann, Perlman and Simpsim-Golabi-Behmel syndromes: a diagnostic pitfall. Clin. Genet. 47:257-262.
38. Veugelers, M., J. Vermeesch, G. Reekmans, R. Steinfeld, P. Marynen, and G. David. 1997. Characterization of glypican-5 and chromosomal localization of human GPC5, a new member of the glypican gene family. Genomics. 40:24-30.
39. Watanabe, K., H. Yamada, and Y. Yamaguchi. 1995. K-glypican: a novel GPI-linked heparan sulfate proteoglycan that is highly expressed in developing brain and kidney. J. Cell Biol. 130:1207-1218.
40. Weksberg, R., J.A. Squire, and D.M. Templeton. 1996. Glypicans: a growing trend. Nat. Genet. 12:225-227.
41. Wight, T.N., M.G. Kinsella, and E. Qwarnstrom. 1992. The role of proteoglycans in cell adhesion, migration and proliferation. Curr. Opin. Cell Biol. 4:793-801.