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Volumn 810, Issue 1-2, 1998, Pages 181-199

Glutamate receptor antagonists inhibit calpain-mediated cytoskeletal proteolysis in focal cerebral ischemia

Author keywords

Calpain; Cerebral ischemia; Microtubule associated protein; Neuronal degeneration

Indexed keywords

CALPAIN; GLUTAMATE RECEPTOR ANTAGONIST; MICROTUBULE ASSOCIATED PROTEIN;

EID: 0032501191     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00921-4     Document Type: Article
Times cited : (66)

References (66)
  • 1
    • 0001454672 scopus 로고    scopus 로고
    • The calpain hypothesis of neurodegeneration: Evidence for a common cytotoxic pathway
    • Bartus R.T. The calpain hypothesis of neurodegeneration: evidence for a common cytotoxic pathway. The Neuroscientist. 3:1997;314-327.
    • (1997) The Neuroscientist , vol.3 , pp. 314-327
    • Bartus, R.T.1
  • 2
    • 0028850474 scopus 로고
    • Time-related neuronal changes following middle cerebral artery occlusion: Implications for therapeutic intervention and the role of calpain
    • Bartus R.T., Dean R.L., Cavanaugh K., Eveleth D., Carriero D.L., Lynch G. Time-related neuronal changes following middle cerebral artery occlusion: implications for therapeutic intervention and the role of calpain. J. Cereb. Blood Flow Metab. 15:1995;969-979.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 969-979
    • Bartus, R.T.1    Dean, R.L.2    Cavanaugh, K.3    Eveleth, D.4    Carriero, D.L.5    Lynch, G.6
  • 3
    • 0023502387 scopus 로고
    • Subcellular compartmentalization of calcium-dependent and calcium-independent neutral proteases in brain
    • Baudry M., DuBrin R., Lynch G. Subcellular compartmentalization of calcium-dependent and calcium-independent neutral proteases in brain. Synapse. 1:1987;506-511.
    • (1987) Synapse , vol.1 , pp. 506-511
    • Baudry, M.1    Dubrin, R.2    Lynch, G.3
  • 4
    • 0022870943 scopus 로고
    • Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats
    • Bederson J.B., Pitts L.H., Germano S.M., Nishimura M.C., Davis R.L., Bartkowski H.M. Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke. 17:1986;472-476.
    • (1986) Stroke , vol.17 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Germano, S.M.3    Nishimura, M.C.4    Davis, R.L.5    Bartkowski, H.M.6
  • 5
    • 0021707433 scopus 로고
    • Elevation of extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
    • Benveniste H., Drejer J., Schousboe A., Diemer N.H. Elevation of extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43:1984;1369-1374.
    • (1984) J. Neurochem. , vol.43 , pp. 1369-1374
    • Benveniste, H.1    Drejer, J.2    Schousboe, A.3    Diemer, N.H.4
  • 7
    • 0022365608 scopus 로고
    • The distribution of tau in the mammalian central nervous system
    • Binder L.I., Frankfurter A., Rebhun L.I. The distribution of tau in the mammalian central nervous system. J. Cell Biol. 101:1985;1371-1378.
    • (1985) J. Cell Biol. , vol.101 , pp. 1371-1378
    • Binder, L.I.1    Frankfurter, A.2    Rebhun, L.I.3
  • 9
    • 0023856682 scopus 로고
    • The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils
    • Boast C.A., Gerhardt S.C., Pastor G., Lehmann J., Etienne P.E., Liebman J.M. The N-methyl-D-aspartate antagonists CGS 19755 and CPP reduce ischemic brain damage in gerbils. Brain Res. 442:1988;345-348.
    • (1988) Brain Res. , vol.442 , pp. 345-348
    • Boast, C.A.1    Gerhardt, S.C.2    Pastor, G.3    Lehmann, J.4    Etienne, P.E.5    Liebman, J.M.6
  • 10
    • 0023786051 scopus 로고
    • Focal brain ischemia in the rat: Methods for reproducible neocortical infarction using tandem occlusion of the distal middle cerebral artery and ipsilateral common carotid arteries
    • Brint S., Jacewicz M., Kiessling M., Tanabe J., Pulsinelli W. Focal brain ischemia in the rat: methods for reproducible neocortical infarction using tandem occlusion of the distal middle cerebral artery and ipsilateral common carotid arteries. J. Cereb. Blood Flow Metab. 8:1988;474-485.
    • (1988) J. Cereb. Blood Flow Metab. , vol.8 , pp. 474-485
    • Brint, S.1    Jacewicz, M.2    Kiessling, M.3    Tanabe, J.4    Pulsinelli, W.5
  • 11
    • 0025012714 scopus 로고
    • Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia
    • Buchan A., Pulsinelli W.A. Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia. J. Neurosci. 10:1990;311-316.
    • (1990) J. Neurosci. , vol.10 , pp. 311-316
    • Buchan, A.1    Pulsinelli, W.A.2
  • 12
    • 0025603178 scopus 로고
    • Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion
    • Butcher S.P., Bullock R., Graham D.I., McCullough J. Correlation between amino acid release and neuropathologic outcome in rat brain following middle cerebral artery occlusion. Stroke. 21:1990;1727-1733.
    • (1990) Stroke , vol.21 , pp. 1727-1733
    • Butcher, S.P.1    Bullock, R.2    Graham, D.I.3    McCullough, J.4
  • 13
    • 0025831476 scopus 로고
    • Calcium-activated neutral protease (calpain) system: Structure, function, and regulation
    • Croall D.E., DeMartino G.N. Calcium-activated neutral protease (calpain) system: structure, function, and regulation. Physiol. Rev. 71:1991;813-847.
    • (1991) Physiol. Rev. , vol.71 , pp. 813-847
    • Croall, D.E.1    Demartino, G.N.2
  • 14
    • 0029123294 scopus 로고
    • The phosphorylation state of the microtubule-associated protein tau as affected by glutamate, colchicine and β-amyloid in primary rat cortical neuronal cultures
    • Davis D.R., Brion J.P., Couck A.M., Gallo J.M., Hanger D.P., Ladhani K., Lewis C., Lewis C.C.J., Rupniak T., Smith C., Anderton B.H. The phosphorylation state of the microtubule-associated protein tau as affected by glutamate, colchicine and β-amyloid in primary rat cortical neuronal cultures. Biochem. J. 309:1995;941-949.
    • (1995) Biochem. J. , vol.309 , pp. 941-949
    • Davis, D.R.1    Brion, J.P.2    Couck, A.M.3    Gallo, J.M.4    Hanger, D.P.5    Ladhani, K.6    Lewis, C.7    Lewis, C.C.J.8    Rupniak, T.9    Smith, C.10    Anderton, B.H.11
  • 15
    • 0030029825 scopus 로고    scopus 로고
    • Acute focal ischemia-induced alterations in MAP2 immunostaining: Description of temporal changes and utilization as a marker for volumetric assessment of acute brain injury
    • Dawson D.A., Hallenbeck J.M. Acute focal ischemia-induced alterations in MAP2 immunostaining: description of temporal changes and utilization as a marker for volumetric assessment of acute brain injury. J. Cereb. Blood Flow Metab. 16:1996;170-174.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 170-174
    • Dawson, D.A.1    Hallenbeck, J.M.2
  • 16
    • 0027171627 scopus 로고
    • Threshold of calcium disturbances after focal cerebral ischemia in rats. Implications of the window of therapeutic opportunity
    • DeGraba T.J., Ostrow P.T., Grotta J.C. Threshold of calcium disturbances after focal cerebral ischemia in rats. Implications of the window of therapeutic opportunity. Stroke. 24:1993;1212-1217.
    • (1993) Stroke , vol.24 , pp. 1212-1217
    • Degraba, T.J.1    Ostrow, P.T.2    Grotta, J.C.3
  • 18
    • 0027521274 scopus 로고
    • Neuronal vacuolization and necrosis induced by the noncompetitive N-methyl-D-aspartate (NMDA) antagonist MK(+)801 (dizocilpine maleate): A light and electron microscopic evaluation of the rat retrosplenial cortex
    • Fix A.S., Horn J.W., Wightman K.A., Johnson C.A., Long G.G., Storts R.W., Farber N., Wozniak D.F., Olney J.W. Neuronal vacuolization and necrosis induced by the noncompetitive N-methyl-D-aspartate (NMDA) antagonist MK(+)801 (dizocilpine maleate): a light and electron microscopic evaluation of the rat retrosplenial cortex. Exp. Neurol. 123:1993;204-215.
    • (1993) Exp. Neurol. , vol.123 , pp. 204-215
    • Fix, A.S.1    Horn, J.W.2    Wightman, K.A.3    Johnson, C.A.4    Long, G.G.5    Storts, R.W.6    Farber, N.7    Wozniak, D.F.8    Olney, J.W.9
  • 19
    • 0028006179 scopus 로고
    • Effects of intrahippocampal colchicine administration on the levels and localization of microtubule-associated proteins, tau and MAP2
    • Geddes J.W., Bondada M., Keller J.N. Effects of intrahippocampal colchicine administration on the levels and localization of microtubule-associated proteins, tau and MAP2. Brain Res. 633:1994;1-8.
    • (1994) Brain Res. , vol.633 , pp. 1-8
    • Geddes, J.W.1    Bondada, M.2    Keller, J.N.3
  • 20
    • 0029971924 scopus 로고    scopus 로고
    • Permanent focal and transient global cerebral ischemia increase glial and neuronal expression of heme oxygenase-1, but not heme oxygenase-2, protein in rat brain
    • Geddes J.W., Pettigrew L.C., Holtz M.L., Craddock S.D., Maines M.D. Permanent focal and transient global cerebral ischemia increase glial and neuronal expression of heme oxygenase-1, but not heme oxygenase-2, protein in rat brain. Neurosci. Lett. 210:1996;205-208.
    • (1996) Neurosci. Lett. , vol.210 , pp. 205-208
    • Geddes, J.W.1    Pettigrew, L.C.2    Holtz, M.L.3    Craddock, S.D.4    Maines, M.D.5
  • 22
    • 0026710232 scopus 로고
    • The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischemia model
    • Gill R., Nordholm L., Lodge D. The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischemia model. Brain Res. 580:1992;35-43.
    • (1992) Brain Res. , vol.580 , pp. 35-43
    • Gill, R.1    Nordholm, L.2    Lodge, D.3
  • 25
    • 0024429317 scopus 로고
    • Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis
    • Hillered L., Hallström A., Segersvärd S., Persson L., Ungerstedt U. Dynamics of extracellular metabolites in the striatum after middle cerebral artery occlusion in the rat monitored by intracerebral microdialysis. J. Cereb. Blood Flow Metab. 9:1989;607-616.
    • (1989) J. Cereb. Blood Flow Metab. , vol.9 , pp. 607-616
    • Hillered, L.1    Hallström, A.2    Segersvärd, S.3    Persson, L.4    Ungerstedt, U.5
  • 26
    • 0025184647 scopus 로고
    • Suppressive effect of E-64c on ischemic degradation of cerebral proteins following occlusion of the middle cerebral artery in rats
    • Inuzuka T., Tamura A., Sato S., Kirino T., Toyoshima I., Miyatake T. Suppressive effect of E-64c on ischemic degradation of cerebral proteins following occlusion of the middle cerebral artery in rats. Brain Res. 526:1990;177-179.
    • (1990) Brain Res. , vol.526 , pp. 177-179
    • Inuzuka, T.1    Tamura, A.2    Sato, S.3    Kirino, T.4    Toyoshima, I.5    Miyatake, T.6
  • 27
    • 0029889986 scopus 로고    scopus 로고
    • Intracortical perfusion of glutamate in vivo induces alterations of tau and microtubule-associated protein 2 immunoreactivity in the rat
    • Irving E.A., McCulloch J., Dewar D. Intracortical perfusion of glutamate in vivo induces alterations of tau and microtubule-associated protein 2 immunoreactivity in the rat. Acta Neuropathol. 92:1996;186-196.
    • (1996) Acta Neuropathol. , vol.92 , pp. 186-196
    • Irving, E.A.1    McCulloch, J.2    Dewar, D.3
  • 29
    • 0025731595 scopus 로고
    • Degradation of microtubule-associated protein 2 and brain spectrin by calpain: A comparative study
    • Johnson G.V.W., Litersky J.M., Jope R.S. Degradation of microtubule-associated protein 2 and brain spectrin by calpain: a comparative study. J. Neurochem. 56:1991;1630-1638.
    • (1991) J. Neurochem. , vol.56 , pp. 1630-1638
    • Johnson, G.V.W.1    Litersky, J.M.2    Jope, R.S.3
  • 30
    • 0020051129 scopus 로고
    • Delayed neuronal death in the gerbil hippocampus following ischaemia
    • Kirino T. Delayed neuronal death in the gerbil hippocampus following ischaemia. Brain Res. 239:1982;57-69.
    • (1982) Brain Res. , vol.239 , pp. 57-69
    • Kirino, T.1
  • 32
    • 0031953601 scopus 로고    scopus 로고
    • Calcium in ischemic cell death
    • Kristián T., Siesjö B.K. Calcium in ischemic cell death. Stroke. 29:1998;705-718.
    • (1998) Stroke , vol.29 , pp. 705-718
    • Kristián, T.1    Siesjö, B.K.2
  • 33
    • 0026537712 scopus 로고
    • The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat
    • Le Peillet E., Arvin B., Moncada C., Meldrum B.S. The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat. Brain Res. 571:1992;115-120.
    • (1992) Brain Res. , vol.571 , pp. 115-120
    • Le Peillet, E.1    Arvin, B.2    Moncada, C.3    Meldrum, B.S.4
  • 35
    • 0027445864 scopus 로고
    • Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury
    • Li H., Buchan A.M. Treatment with an AMPA antagonist 12 hours following severe normothermic forebrain ischemia prevents CA1 neuronal injury. J. Cereb. Blood Flow Metab. 13:1993;933-939.
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 933-939
    • Li, H.1    Buchan, A.M.2
  • 36
    • 0029935974 scopus 로고    scopus 로고
    • Regional differences in gene expression for calcium activated neutral proteases (calpains) and their endogenous inhibitor calpastatin in mouse brain and spinal cord
    • Li J., Grynspan F., Berman S., Nixon R., Bursztajn S. Regional differences in gene expression for calcium activated neutral proteases (calpains) and their endogenous inhibitor calpastatin in mouse brain and spinal cord. J. Neurobiol. 30:1996;177-191.
    • (1996) J. Neurobiol. , vol.30 , pp. 177-191
    • Li, J.1    Grynspan, F.2    Berman, S.3    Nixon, R.4    Bursztajn, S.5
  • 37
    • 0026597280 scopus 로고
    • Phosphorylation by cAMP-dependent protein kinase inhibits the degradation of tau by calpain
    • Litersky J.M., Johnson G.V.W. Phosphorylation by cAMP-dependent protein kinase inhibits the degradation of tau by calpain. J. Biol. Chem. 267:1992;1563-1568.
    • (1992) J. Biol. Chem. , vol.267 , pp. 1563-1568
    • Litersky, J.M.1    Johnson, G.V.W.2
  • 38
    • 0025993117 scopus 로고
    • Glutamate neurotoxicity is independent of calpain I inhibition in primary cultures of cerebellar granule cells
    • Manev H., Favaron M., Siman R., Guidotti A., Costa E. Glutamate neurotoxicity is independent of calpain I inhibition in primary cultures of cerebellar granule cells. J. Neurochem. 57:1991;1288-1295.
    • (1991) J. Neurochem. , vol.57 , pp. 1288-1295
    • Manev, H.1    Favaron, M.2    Siman, R.3    Guidotti, A.4    Costa, E.5
  • 40
    • 0028087618 scopus 로고
    • Microtubule-associated protein 2 as an early indicator of ischemia-induced neurodegeneration in the gerbil forebrain
    • Matesic D.F., Lin R.C.S. Microtubule-associated protein 2 as an early indicator of ischemia-induced neurodegeneration in the gerbil forebrain. J. Neurochem. 63:1994;1012-1020.
    • (1994) J. Neurochem. , vol.63 , pp. 1012-1020
    • Matesic, D.F.1    Lin, R.C.S.2
  • 42
    • 0029039987 scopus 로고
    • Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau
    • Mercken M., Grynspan F., Nixon R.A. Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau. FEBS Letters. 368:1995;10-14.
    • (1995) FEBS Letters , vol.368 , pp. 10-14
    • Mercken, M.1    Grynspan, F.2    Nixon, R.A.3
  • 43
    • 0027299234 scopus 로고
    • Temperature effect on immunostaining of microtubule-associated protein 2 and synaptophysin after 30 minutes of forebrain ischemia
    • Miyazawa T., Bonnekoh P., Hossman K.A. Temperature effect on immunostaining of microtubule-associated protein 2 and synaptophysin after 30 minutes of forebrain ischemia. Acta Neuropathol. 85:1993;526-532.
    • (1993) Acta Neuropathol. , vol.85 , pp. 526-532
    • Miyazawa, T.1    Bonnekoh, P.2    Hossman, K.A.3
  • 44
    • 0026505401 scopus 로고
    • Postischemic blockage of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia
    • Nellgård B., Wieloch T. Postischemic blockage of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia. J. Cereb. Blood Flow Metab. 12:1992;2-11.
    • (1992) J. Cereb. Blood Flow Metab. , vol.12 , pp. 2-11
    • Nellgård, B.1    Wieloch, T.2
  • 45
    • 0025285178 scopus 로고
    • Distribution of calcium-activated protease calpain in the rat brain
    • Perlmutter L.S., Gall C., Baudry M., Lynch G. Distribution of calcium-activated protease calpain in the rat brain. J. Comp. Neurol. 296:1990;269-276.
    • (1990) J. Comp. Neurol. , vol.296 , pp. 269-276
    • Perlmutter, L.S.1    Gall, C.2    Baudry, M.3    Lynch, G.4
  • 46
    • 0023866466 scopus 로고
    • The ultrastructural localization of calcium-activated protease 'calpain' in rat brain
    • Perlmutter L.S., Siman R., Gall C., Seubert P., Baudry M., Lynch G. The ultrastructural localization of calcium-activated protease 'calpain' in rat brain. Synapse. 2:1988;79-88.
    • (1988) Synapse , vol.2 , pp. 79-88
    • Perlmutter, L.S.1    Siman, R.2    Gall, C.3    Seubert, P.4    Baudry, M.5    Lynch, G.6
  • 48
    • 0027215039 scopus 로고
    • Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo
    • Rami A., Krieglstein J. Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo. Brain Res. 609:1993;67-70.
    • (1993) Brain Res. , vol.609 , pp. 67-70
    • Rami, A.1    Krieglstein, J.2
  • 49
    • 0028282502 scopus 로고
    • Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain
    • Roberts-Lewis J.M., Savage M.J., Marcy V.L., Pinsker L.R., Siman R. Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain. J. Neurosci. 14:1994;3934-3944.
    • (1994) J. Neurosci. , vol.14 , pp. 3934-3944
    • Roberts-Lewis, J.M.1    Savage, M.J.2    Marcy, V.L.3    Pinsker, L.R.4    Siman, R.5
  • 50
    • 0027981303 scopus 로고
    • Postmortem changes in the levels and localization of microtubule-associated proteins (tau, MAP2 and MAP1B) in the rat and human hippocampus
    • Schwab C., Bondada V., Sparks D.L., Cahan L.D., Geddes J.W. Postmortem changes in the levels and localization of microtubule-associated proteins (tau, MAP2 and MAP1B) in the rat and human hippocampus. Hippocampus. 4:1994;210-225.
    • (1994) Hippocampus , vol.4 , pp. 210-225
    • Schwab, C.1    Bondada, V.2    Sparks, D.L.3    Cahan, L.D.4    Geddes, J.W.5
  • 51
    • 0023766340 scopus 로고
    • Stimulation of NMDA receptors induces proteolysis of spectrin in hippocampus
    • Seubert P., Larson J., Oliver M., Jung M.W., Baudry M., Lynch G. Stimulation of NMDA receptors induces proteolysis of spectrin in hippocampus. Brain Res. 460:1988;189-194.
    • (1988) Brain Res. , vol.460 , pp. 189-194
    • Seubert, P.1    Larson, J.2    Oliver, M.3    Jung, M.W.4    Baudry, M.5    Lynch, G.6
  • 52
    • 0024347477 scopus 로고
    • Ischemia triggers NMDA receptor-linked cytoskeletal proteolysis in hippocampus
    • Seubert P., Lee K., Lynch G. Ischemia triggers NMDA receptor-linked cytoskeletal proteolysis in hippocampus. Brain Res. 492:1989;366-370.
    • (1989) Brain Res. , vol.492 , pp. 366-370
    • Seubert, P.1    Lee, K.2    Lynch, G.3
  • 53
    • 0025786634 scopus 로고
    • MK-801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex
    • Sharp F.R., Jasper P., Hall J., Noble L., Sagar S.M. MK-801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex. Ann. Neurol. 30:1991;801-809.
    • (1991) Ann. Neurol. , vol.30 , pp. 801-809
    • Sharp, F.R.1    Jasper, P.2    Hall, J.3    Noble, L.4    Sagar, S.M.5
  • 54
    • 0025117827 scopus 로고
    • 2,3-dihyroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: A neuroprotectant for cerebral ischemia
    • Sheardown M.J., Nielsen E.O., Hansen A.J., Jacobsen P., Honore T. 2,3-dihyroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia. Science. 247:1990;571-574.
    • (1990) Science , vol.247 , pp. 571-574
    • Sheardown, M.J.1    Nielsen, E.O.2    Hansen, A.J.3    Jacobsen, P.4    Honore, T.5
  • 55
    • 0024020782 scopus 로고
    • Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo
    • Siman R., Noszek J.C. Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo. Neuron. 1:1988;279-287.
    • (1988) Neuron , vol.1 , pp. 279-287
    • Siman, R.1    Noszek, J.C.2
  • 56
    • 0024363137 scopus 로고
    • Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage
    • Siman R., Noszek J.C., Kegerise C. Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage. J. Neurosci. 9:1989;1579-1590.
    • (1989) J. Neurosci. , vol.9 , pp. 1579-1590
    • Siman, R.1    Noszek, J.C.2    Kegerise, C.3
  • 57
    • 0025309389 scopus 로고
    • N-methyl-D-aspartate antagonist reduces stroke size and regional glucose metabolism
    • Simon R.P., Shiraishi K. N-methyl-D-aspartate antagonist reduces stroke size and regional glucose metabolism. Ann. Neurol. 27:1990;606-611.
    • (1990) Ann. Neurol. , vol.27 , pp. 606-611
    • Simon, R.P.1    Shiraishi, K.2
  • 59
    • 0031452173 scopus 로고    scopus 로고
    • Structure and physiological function of calpains
    • Sorimachi H., Ishiura S., Suzuki K. Structure and physiological function of calpains. Biochem. J. 328:1997;721-732.
    • (1997) Biochem. J. , vol.328 , pp. 721-732
    • Sorimachi, H.1    Ishiura, S.2    Suzuki, K.3
  • 61
    • 0026703324 scopus 로고
    • Absence of early destructive changes of cytoskeletal proteins after transient ischemia in the rat
    • Tomioka C., Nishioka H., Kogure K. Absence of early destructive changes of cytoskeletal proteins after transient ischemia in the rat. Brain Res. 586:1992;352-357.
    • (1992) Brain Res. , vol.586 , pp. 352-357
    • Tomioka, C.1    Nishioka, H.2    Kogure, K.3
  • 63
    • 0022525549 scopus 로고
    • Cerebral ischemia in the gerbil: Transmission electron microscopic and immunoelectron microscopic investigation
    • Yamamoto K., Morimoto K., Yanagihara T. Cerebral ischemia in the gerbil: transmission electron microscopic and immunoelectron microscopic investigation. Brain Res. 384:1986;1-10.
    • (1986) Brain Res. , vol.384 , pp. 1-10
    • Yamamoto, K.1    Morimoto, K.2    Yanagihara, T.3
  • 65
    • 0028785672 scopus 로고
    • Calpain-induced proteolysis of normal human tau and tau associated with paired helical filaments
    • Yang L.S., Ksiezak-Reding H. Calpain-induced proteolysis of normal human tau and tau associated with paired helical filaments. Eur. J. Biochem. 233:1995;9-17.
    • (1995) Eur. J. Biochem. , vol.233 , pp. 9-17
    • Yang, L.S.1    Ksiezak-Reding, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.