Activin A/bone morphogenetic protein (BMP) chimeras exhibit BMP-like activity and antagonize activin and myostatin

Journal of Biological Chemistry

Volumn 283, Issue 7, 2008, Pages 3782-3790

  Korupolu, Radhika V ^a   Muenster, Uwe ^a   Read, Jessica D ^a   Vale, Wylie ^a   Fischer, Wolfgang H ^a,b  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOACTIVITY; CELL GROWTH; CELL MEMBRANES; DIFFERENTIATION (CALCULUS); GROWTH (MATERIALS); INTERNET; LIGANDS; MODULATION; PEPTIDES; PROTEINS;

ALKALINE PHOSPHATASES; BINDING AFFINITIES; BONE MORPHOGENETIC PROTEINS; CELL SURFACES; CENTRAL REGIONS; HEPG2 CELLS; MORPHOGENETIC PROTEINS; MYOSTATIN; REPORTER ASSAYS; T CELLS; TARGET CELLS; TERMINAL REGIONS; TRANSFORMING GROWTH FACTORS; TYPE II; WILD TYPES;

GLYCOPROTEINS;

ACTIVIN A; ACTIVIN RECEPTOR 2; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; MYOSTATIN; OSTEOGENIC PROTEIN 1; SMAD1 PROTEIN; SMAD2 PROTEIN; ACTIVIN; BONE MORPHOGENETIC PROTEIN; HYBRID PROTEIN; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL STRAIN HEPG2; CHIMERA; HUMAN; HUMAN CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RAT; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; SEQUENCE HOMOLOGY;

ACTIVINS; AMINO ACID SEQUENCE; ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL LINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MOLECULAR SEQUENCE DATA; RATS; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 42949168652     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M704530200     Document Type: Article

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