Hepatic ABCG5 and ABCG8 overexpression increases hepatobiliary sterol transport but does not alter aortic atherosclerosis in transgenic mice

Journal of Biological Chemistry

Volumn 279, Issue 22, 2004, Pages 22913-22925

  Wu, Justina E ^a   Basso, Federica ^a   Shamburek, Robert D ^a   Amar, Marcelo J A ^a   Vaisman, Boris ^a   Szakacs, Gergely ^b   Joyce, Charles ^a   Tansey, Terese ^a   Freeman, Lita ^a   Paigen, Beverly J ^c   Thomas, Fairwell ^a   Brewer Jr , H Bryan ^a   Santamarina Fojo, Silvia ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTION; BIOLOGICAL ORGANS; CHOLESTEROL; GENETIC ENGINEERING; METABOLISM;

ATHEROSCELOROSIS; HEPATIC OVEREXPRESSION; STEROL TRANSPORT;

BIOCHEMISTRY;

LOW DENSITY LIPOPROTEIN RECEPTOR; PHYTOSTEROL; PROTEIN; PROTEIN ABCG5; PROTEIN ABCG8; UNCLASSIFIED DRUG;

ANIMAL CELL; AORTA ATHEROSCLEROSIS; ARTICLE; BILE SECRETION; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DIETARY INTAKE; FECES; GENE OVEREXPRESSION; HEPATOBILIARY SYSTEM; INTESTINE ABSORPTION; LIPID BLOOD LEVEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEROL METABOLISM; TRANSGENIC MOUSE;

ANIMALS; AORTA; ARTERIOSCLEROSIS; ATP-BINDING CASSETTE TRANSPORTERS; BILIARY TRACT; BIOLOGICAL TRANSPORT; CHOLESTEROL, DIETARY; DIET; GENE EXPRESSION REGULATION; HUMANS; LIPOPROTEINS; LIVER; MICE; MICE, TRANSGENIC; STEROLS;

ANIMALIA; MUS MUSCULUS;

EID: 2542427448     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402838200     Document Type: Article

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