Polycystin-1 induced apoptosis and cell cycle arrest in G0/G1 phase in cancer cells

Cell Biology International

Volumn 32, Issue 4, 2008, Pages 427-435

  Zheng, Rong ^a   Zhang, Zheng ^a   Lv, Xiaoyan ^a   Fan, JunMing ^a   Chen, Ye ^a   Wang, Yidong ^a   Tan, Ruizhi ^a   Liu, Yuhang ^a   Zhou, Qin ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Apoptosis; Cell cycle; Polycystin 1; Proliferation; Wnt pathway

Indexed keywords

POLYCYSTIN 1; WNT PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELL STRAIN HEPG2; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CELL PROLIFERATION; FLOW CYTOMETRY; G0 PHASE; G1 PHASE; HUMANS; NEOPLASMS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TRPP CATION CHANNELS; UP-REGULATION; WNT PROTEINS;

EID: 42749093528     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2007.12.014     Document Type: Article

References (33)

1. Arnaout M.A. Molecular genetics and pathogenesis of autosomal dominant polycystic kidney disease. Annu Rev Med 52 (2001) 93-123
2. Bhunia A.K., Piontek K., Boletta A., et al. PKD1 induces p21wafl and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2. Cell 109 (2002) 157-168
3. Bienz M., and Clevers H. Armadillo/β-catenin signals in the nucleus-proof beyond a reasonable doubt?. Nat Cell Biol 5 (2003) 179-182
4. Boletta A., Qian F., Onuchic L.F., et al. The molecular basis of focal cyst formation in human autosomal dominant induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells. Mol Cell 6 (2000) 1267-1273
5. Couillard M., Guillaume R., Tanji N., et al. c-myc-induced apoptosis in polycystic kidney disease is independent of FasL/Fas interaction 1. Cancer Res 62 (2002) 2210-2214
6. Dang C.V., Resar L.M., Emison E., et al. Function of the c-Myc oncogenic transcription factor. Exp Cell Res 253 (1999) 63-77
7. Fossdal R., Bothvarsson M., Asmundsson P., et al. Icelandic families with autosomal dominant polycystic kidney disease: families unlinked to chromosome 16p13.3 revealed by linkage analysis. Hum Genet 91 (1993) 609-613
8. Gabow P.A. Autosomal dominant polycystic kidney disease. N Engl J Med 329 (1993) 332-342
9. Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
10. Huan Y., and Van A.J. Polycystin-1, the PKD1 gene product, is in a complex containing E-cardherin and the catenins. J Clin Invest 104 (1999) 1459-1468
11. Igarashi P., and Somlo S. Genetics and pathogenesis of polycystic kidney disease. J Am Soc Nephrol 13 (2002) 2384-2398
12. Kim E., Arnould T., Sellin L.K., Drummond I., and Walz G. The polycystic kidney disease 1 gene product modulates Wnt signaling. J Biol Chem 274 (1999) 4947-4953
13. Kim H., Bae Y., Jeong W., et al. Depletion of PKD1 by an antisense oligodeoxynucleotide induces premature G1/S-phase transition. Eur J Hum Genet 12 (2004) 433-440
14. Krammer P.H., Galle P.R., and Moller P. CD95 (APO-1/Fas)-mediated apoptosis in normal and malignant liver, colon, and hematopoietic cells. Adv Cancer Res 75 (1998) 251-273
15. Lanoix J., D'Agati V., Szabolcs M., et al. Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant polycystic kidney disease(ADPKD). Oncogene 13 (1996) 1153-1160
16. Liu C., Li Y., Semenov M., et al. Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 108 (2002) 837-847
17. Lockshin R.A., and Zakeri Z. Caspase-independent cell death?. Oncogene 23 (2004) 2766-2773
18. Mary C., and Abraham Shai S. Death without caspases, caspases without death. Trends Cell Biol 14 (2004) 184-193
19. Moon R.T., Bowerman B., Boutros M., et al. The promise and perils of Wnt signaling through beta-catenin. Science 296 (2002) 1644-1646
20. Moser M., Pscherer A., Roth C., et al. Enhanced apoptotic cell death of renal epithelial cells in mice lacking. transcription factor AP-2beta. Genes Dev 11 (1997) 1938-1948
21. Nicholson D.W., Ali A., Thornberry N.A., et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376 (1995) 37-43
22. Nusse R. Wnts and Hedgehogs. Lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development 130 (2003) 5297-5305
23. Roitbak T., Ward C.J., and Harris P.C. A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells. Mol Biol Cell 15 (2004) 1334-1346
24. Ruel L., Stambolic V., Ali A., et al. Regulation of the protein kinase activity of Shaggy (Zeste-white3) by components of the wingless pathway in Drosophila cells and embryos. J Biol Chem 274 (1999) 21790-21796
25. Sandford R., Sgotto B., Aparicio S., et al. Comparative analysis of the polycystic kidney disease 1 (PKD1) gene reveals an integral membrane glycoprotein with multiple evolutionary conserved domains. Hum Mol Genet 6 (1997) 1483-1489
26. Satoru M., Atsa A., and Yuichirou S. Pioglitazone improves the phenotype and molecular defects of a targeted PKD1 mutant. Hum Mol Genet 11 (2002) 1731-1742
27. Trudel M., Lanoix J., Barisoni L., et al. c-myc-induced apoptosis in polycystic kidney disease is Bcl-2 and p53 independent. J Exp Med 186 (1997) 1873-1884
28. Veis D.J., Sorenson C.M., Shutter J.R., Korsmeyer S.J., et al. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75 (1993) 229-240
29. Vermeulen K., Berneman Z.N., and Van D.R. Cell cycle and apoptosis. Cell Prolif 36 (2003) 165-175
30. Willert K., Brown J.D., Danenberg E., et al. Wnt proteins are lipid modified and can act as stem cell growth factors. Nature 423 (2003) 448-452
31. Wilson P.D. Polycystin. new aspects of structure, function and regulation. J Am Soc Nephrol 12 (2001) 834-845
32. Winyard P.J., Nauta J., Lirenman D.S., et al. Deregulation of cell survival in cystic and dysplastic renal development. Kidney Int 49 (1996) 135-146
33. Woo D. Apoptosis and loss of renal tissue in polycystic kidney disease. N Engl J Med 333 (1995) 18-25