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Volumn 18, Issue 1, 1997, Pages 185-192

Lung carcinogenesis and formation of 8-hydroxy-deoxyguanosine in mice by diesel exhaust particles

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BETA CAROTENE; DIESEL FUEL; OXYGEN RADICAL;

EID: 0031419002     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/18.1.185     Document Type: Article
Times cited : (208)

References (55)
  • 2
    • 0020959016 scopus 로고
    • A long-term inhalation study evaluates the pulmonary effects of diesel emissions
    • White,H., Vostal,J.J., Kaplan,H. and MacKenzie,W.F. (1983) A long-term inhalation study evaluates the pulmonary effects of diesel emissions. J. Appl. Toxicol., 3, 332.
    • (1983) J. Appl. Toxicol. , vol.3 , pp. 332
    • White, H.1    Vostal, J.J.2    Kaplan, H.3    MacKenzie, W.F.4
  • 3
    • 0022994002 scopus 로고
    • Chronic effects on the respiratory tract of hamsters, mice and rats after long-term inhalation of high concentrations of filtered and unfiltered diesel engine emissions
    • Heinrich,U., Muhle,H., Takenaka.S., Ernst,H., Fuhst,R., Mohr,U., Pott,F. and Stober,W. (1986) Chronic effects on the respiratory tract of hamsters, mice and rats after long-term inhalation of high concentrations of filtered and unfiltered diesel engine emissions, J. Appl. Toxicol., 6, 383-395.
    • (1986) J. Appl. Toxicol. , vol.6 , pp. 383-395
    • Heinrich, U.1    Muhle, H.2    Takenaka, S.3    Ernst, H.4    Fuhst, R.5    Mohr, U.6    Pott, F.7    Stober, W.8
  • 4
    • 0022634377 scopus 로고
    • Chronic inhalation studies of diesel exhaust gas - Morphological changes observed in intra- and extra-pulmonary organs
    • Iwai,K., Udagawa,T., Yamagishi,M. and Yamada,H. (1986) Chronic inhalation studies of diesel exhaust gas - Morphological changes observed in intra- and extra-pulmonary organs. J. Japan. Soc. Air Pottut., 21, 38-51.
    • (1986) J. Japan. Soc. Air Pottut. , vol.21 , pp. 38-51
    • Iwai, K.1    Udagawa, T.2    Yamagishi, M.3    Yamada, H.4
  • 6
    • 0025367336 scopus 로고
    • Long-term inhalation experiments on the health effects of diesel exhaust - The findings on F344 rats in carcinogenicity experiment in terms of dose response relationship
    • Suzuki,T., Nakajima,T., Maejima,K., Kato,A., Takaki,Y., Kuwabara,N., Hisanaga,A. and Ishinishi,N. (1990) Long-term inhalation experiments on the health effects of diesel exhaust - The findings on F344 rats in carcinogenicity experiment in terms of dose response relationship. J. Japan Soc. Air Pallut., 25, 192-205.
    • (1990) J. Japan Soc. Air Pallut. , vol.25 , pp. 192-205
    • Suzuki, T.1    Nakajima, T.2    Maejima, K.3    Kato, A.4    Takaki, Y.5    Kuwabara, N.6    Hisanaga, A.7    Ishinishi, N.8
  • 7
    • 0023160835 scopus 로고
    • Health effects of exposure to diesel exhaust particles
    • McClellan,R.O. (1987) Health effects of exposure to diesel exhaust particles. Ann. Rev. Pharmacol. Toxicol., 27, 279-300.
    • (1987) Ann. Rev. Pharmacol. Toxicol. , vol.27 , pp. 279-300
    • McClellan, R.O.1
  • 8
    • 0020979975 scopus 로고
    • Detection and average content levels of carcinogenic and mutagenic compounds from the particulates on diesel and gasoline engine mufflers
    • Handa,T., Yamauchi,T., Ohnishi,M., Hisamatu,Y. and Ishii,T. (1983) Detection and average content levels of carcinogenic and mutagenic compounds from the particulates on diesel and gasoline engine mufflers. Environ. Internat., 9, 335-342.
    • (1983) Environ. Internat. , vol.9 , pp. 335-342
    • Handa, T.1    Yamauchi, T.2    Ohnishi, M.3    Hisamatu, Y.4    Ishii, T.5
  • 9
    • 2642636079 scopus 로고
    • Enhancement of respiratory carcinogenesis by tracheal wounding from cannulation
    • KeenanK.P., Saffiotti,U., Stinson,S.F., Riggs,C.W. and McDowell,E.M. (1987) Enhancement of respiratory carcinogenesis by tracheal wounding from cannulation. Fed. Proc., 46, 432.
    • (1987) Fed. Proc. , vol.46 , pp. 432
    • KeenanK, P.1    Saffiotti, U.2    Stinson, S.F.3    Riggs, C.W.4    McDowell, E.M.5
  • 11
    • 77957185403 scopus 로고
    • Comparative toxicities and carcinogenicities of chronically inhaled diesel exhaust and carbon black in F344 rats
    • Nikula,K.J., Snipes,M.B., Barr,E.B., Griffith,W.C., Henderson,R.F. and Mauderly,J.L. (1995) Comparative toxicities and carcinogenicities of chronically inhaled diesel exhaust and carbon black in F344 rats. Fundam. Appl. Toxicol., 25, 80-94.
    • (1995) Fundam. Appl. Toxicol. , vol.25 , pp. 80-94
    • Nikula, K.J.1    Snipes, M.B.2    Barr, E.B.3    Griffith, W.C.4    Henderson, R.F.5    Mauderly, J.L.6
  • 12
    • 0001492660 scopus 로고
    • Carcinogenic effects of solid particles
    • Mohr,U., Dungworth,D.L., Mauderly,J.L. and Oberdorster,G. (eds). International Life Sciences Institute (ILSI) Press, Washington, DC
    • Heinrich,U. (1994) Carcinogenic effects of solid particles. In Mohr,U., Dungworth,D.L., Mauderly,J.L. and Oberdorster,G. (eds), Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract. International Life Sciences Institute (ILSI) Press, Washington, DC, pp. 57-73.
    • (1994) Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract , pp. 57-73
    • Heinrich, U.1
  • 13
    • 0003030193 scopus 로고
    • Influence of particle-associated organic compounds on the carcinogenicity of diesel exhaust
    • Mohr,U., Dungworth,D.L., Mauderly,J.L. and Oberdorster,G. (eds). International Life Sciences Institute (ILSI) Press, Washington, DC
    • Dungworth,D.L., Mohr,U., Heinrich,U., Ernst,H. and Kittel,B. (1994) Influence of particle-associated organic compounds on the carcinogenicity of diesel exhaust. In Mohr,U., Dungworth,D.L., Mauderly,J.L. and Oberdorster,G. (eds) Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract. International Life Sciences Institute (ILSI) Press, Washington, DC, pp. 75-98.
    • (1994) Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract , pp. 75-98
    • Dungworth, D.L.1    Mohr, U.2    Heinrich, U.3    Ernst, H.4    Kittel, B.5
  • 14
    • 0027444249 scopus 로고
    • Biological effect of diesel exhaust particles. I. In vitro roduction of superoxide and in vivo toxicity in mouse
    • Sagai,M. Saito,H. Ichinose,T. Kodama,M. and Mori,Y (1993) Biological effect of diesel exhaust particles. I. In vitro roduction of superoxide and in vivo toxicity in mouse. Free Rad. Biol. Med., 14, 37-47.
    • (1993) Free Rad. Biol. Med. , vol.14 , pp. 37-47
    • Sagai, M.1    Saito, H.2    Ichinose, T.3    Kodama, M.4    Mori, Y.5
  • 15
    • 0029030749 scopus 로고
    • Biological effects of diesel exhaust particles (DEP). II. Acute toxicity of DEP introduced into lung by intratracheal instillation
    • Ichinose,T., Furuyama,A. and Sagai,M. (1995) Biological effects of diesel exhaust particles (DEP). II. Acute toxicity of DEP introduced into lung by intratracheal instillation. Toxicology, 99, 153-167.
    • (1995) Toxicology , vol.99 , pp. 153-167
    • Ichinose, T.1    Furuyama, A.2    Sagai, M.3
  • 16
    • 0015789234 scopus 로고
    • Effect of hydrogen peroxide, Fenton's reagent, and irons on the carcinogenicity of 3,4-benzopyrene
    • Nagata,C., Tagashira,Y., Kodama,M., Ioki,Y. and Oboshi,S. (1973) Effect of hydrogen peroxide, Fenton's reagent, and irons on the carcinogenicity of 3,4-benzopyrene. Gann, 46, 277-285.
    • (1973) Gann , vol.46 , pp. 277-285
    • Nagata, C.1    Tagashira, Y.2    Kodama, M.3    Ioki, Y.4    Oboshi, S.5
  • 17
    • 0002738322 scopus 로고
    • Formation of 8-hyaroxydeoxyguanosine in DNA by oxygen radicals and its biological significance
    • Sies,H. (ed), Academic Press Ltd., London
    • Kasai,H. and Nishimura,S. (1991) Formation of 8-hyaroxydeoxyguanosine in DNA by oxygen radicals and its biological significance. In Sies,H. (ed), Oxidative Stress, Oxidant and Antioxidants, Academic Press Ltd., London, pp. 99-116.
    • (1991) Oxidative Stress, Oxidant and Antioxidants , pp. 99-116
    • Kasai, H.1    Nishimura, S.2
  • 18
    • 0021149013 scopus 로고
    • Hydroxylation of deoxyguanosine at the C-8 position by polyphenols and aminophenols in the presence of hydrogen peroxide and ferric ion
    • Kasai,H. and Nishimura,S. (1984) Hydroxylation of deoxyguanosine at the C-8 position by polyphenols and aminophenols in the presence of hydrogen peroxide and ferric ion. Gann, 75, 565-566.
    • (1984) Gann , vol.75 , pp. 565-566
    • Kasai, H.1    Nishimura, S.2
  • 19
    • 0029047758 scopus 로고
    • Formation of an oxidative DNA damage, 8-hydroxy deoxyguanosine, in mouse lung DNA after intratracheal instillation of diesel exhaust particles and effects of high dietary fat and beta-carotene in this process
    • Nagashima,M., Kasai,H., Yokota,J., Nagamachi,Y., Ichinose,T. and Sagai,M. (1995) Formation of an oxidative DNA damage, 8-hydroxy deoxyguanosine, in mouse lung DNA after intratracheal instillation of diesel exhaust particles and effects of high dietary fat and beta-carotene in this process. Carcinogenesis, 16, 1441-1445.
    • (1995) Carcinogenesis , vol.16 , pp. 1441-1445
    • Nagashima, M.1    Kasai, H.2    Yokota, J.3    Nagamachi, Y.4    Ichinose, T.5    Sagai, M.6
  • 20
    • 0026630366 scopus 로고
    • Protection by β-carotene and related compounds against oxygen-mediated cytotoxicity and genotoxicity: Implications for carcinogenesis and anticarcinogencsis
    • Rousseau,E.R., Davison,A.J. and Dunn,B. (1992) Protection by β-carotene and related compounds against oxygen-mediated cytotoxicity and genotoxicity: Implications for carcinogenesis and anticarcinogencsis. Free Rad. Biol. Med., 13, 407-433.
    • (1992) Free Rad. Biol. Med. , vol.13 , pp. 407-433
    • Rousseau, E.R.1    Davison, A.J.2    Dunn, B.3
  • 22
    • 0028339240 scopus 로고
    • Increased formation of oidative DNA damage, 8-hydroxy- Deoxyguanosine, in human livers with chronic hepatitis
    • Shimoda,R., Nagashima,M., Sakamoto,M., Yamaguchi, N., Hirohashi, S., Yokota, J. and Kasai,H. (1994) Increased formation of oidative DNA damage, 8-hydroxy- deoxyguanosine, in human livers with chronic hepatitis. Cancer Res., 54, 3171-3172.
    • (1994) Cancer Res. , vol.54 , pp. 3171-3172
    • Shimoda, R.1    Nagashima, M.2    Sakamoto, M.3    Yamaguchi, N.4    Hirohashi, S.5    Yokota, J.6    Kasai, H.7
  • 23
    • 0026653104 scopus 로고
    • Phenol sensitization of DNA to subsequent oxidative damage in 8-hydroxydeoxyguanosine assays
    • Claycamp, H.G. (1992) Phenol sensitization of DNA to subsequent oxidative damage in 8-hydroxydeoxyguanosine assays. Carcinogenesis, 13, 1289-1292.
    • (1992) Carcinogenesis , vol.13 , pp. 1289-1292
    • Claycamp, H.G.1
  • 24
    • 0022931584 scopus 로고
    • Hydroxyl free radical adduct of deoxyguanosine: Sensitive detecton and mechanisms of formation
    • Floyd,R.A., Watson,J.J., Wong,P.K., Altmiller,D.H. and Rickard,R.C. (1986) Hydroxyl free radical adduct of deoxyguanosine: sensitive detecton and mechanisms of formation. Free Radical Res. Commun., 1, 163-172.
    • (1986) Free Radical Res. Commun. , vol.1 , pp. 163-172
    • Floyd, R.A.1    Watson, J.J.2    Wong, P.K.3    Altmiller, D.H.4    Rickard, R.C.5
  • 25
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel,N. and Haenszel,W. (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl. Cancer Inst., 22, 719-748.
    • (1959) J. Natl. Cancer Inst. , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 26
    • 0000810339 scopus 로고
    • Chi-square tests with one degree of freedom; Extension of the Mantel-Haenszel procedure
    • Mantel,N. (1963) Chi-square tests with one degree of freedom; Extension of the Mantel-Haenszel procedure. Am. Stat. Soc. J., 67, 690-700.
    • (1963) Am. Stat. Soc. J. , vol.67 , pp. 690-700
    • Mantel, N.1
  • 27
    • 0005312032 scopus 로고    scopus 로고
    • Biological effects of diesel exhaust particles. III. Pathogenesis of asthma-like symptoms in mice
    • Sagai,M., Furuyama,A. and Ichinose,T. (1996) Biological effects of diesel exhaust particles. III. Pathogenesis of asthma-like symptoms in mice. Free Rad. Biol Med., 21, 199-209.
    • (1996) Free Rad. Biol Med. , vol.21 , pp. 199-209
    • Sagai, M.1    Furuyama, A.2    Ichinose, T.3
  • 28
    • 0028226146 scopus 로고
    • Formation of DNA adducts in rat lung following chronic inhalation of diesel emissions, carbon black and titanium dioxide particles
    • Gallagner,J., Heinrich,U., George,M., Hendee,L., Phillips,D.H. and Lewtas,J. (1994) Formation of DNA adducts in rat lung following chronic inhalation of diesel emissions, carbon black and titanium dioxide particles. Carcinogenesis, 15, 1291-1299.
    • (1994) Carcinogenesis , vol.15 , pp. 1291-1299
    • Gallagner, J.1    Heinrich, U.2    George, M.3    Hendee, L.4    Phillips, D.H.5    Lewtas, J.6
  • 29
    • 0343203228 scopus 로고
    • Mechanisms and significance of 'particle overload'
    • Mohr, U., Dungworth,D.L., Mauderly,J.L. and Oberdorster,G. (eds). International Life Sciences Institute (ILSI) Press, Washington, DC
    • Morrow,P.E. (1994) Mechanisms and significance of 'particle overload'. In Mohr, U., Dungworth,D.L., Mauderly,J.L. and Oberdorster,G. (eds), Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract. International Life Sciences Institute (ILSI) Press, Washington, DC, pp. 17-25.
    • (1994) Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract , pp. 17-25
    • Morrow, P.E.1
  • 30
    • 77957178203 scopus 로고
    • Possible mechanisms to explain dust overloading of the lungs
    • Morrow,P.E. (1988) Possible mechanisms to explain dust overloading of the lungs. Fundam. Appl. Toxicol., 10, 369-384.
    • (1988) Fundam. Appl. Toxicol. , vol.10 , pp. 369-384
    • Morrow, P.E.1
  • 32
    • 0023636722 scopus 로고
    • Implication of active oxygen species as second messengers of asbestos toxity
    • G. L. Fisher., M. A. Gallo (eds). Marcel Dekker, Inc, New York
    • Mossman,B.T., Marsh,J.P., Shatos,M.A., Doherty,J., Gilbelt,R. and Hill,S. (1988) Implication of active oxygen species as second messengers of asbestos toxity. G. L. Fisher., M. A. Gallo (eds), Asbestos Toxicity. Marcel Dekker, Inc, New York, pp. 157-180.
    • (1988) Asbestos Toxicity , pp. 157-180
    • Mossman, B.T.1    Marsh, J.P.2    Shatos, M.A.3    Doherty, J.4    Gilbelt, R.5    Hill, S.6
  • 33
    • 0031034402 scopus 로고    scopus 로고
    • Generation of reactive oxygen species during interaction of diesel exhaust particles components with NADPH-cytochrome P450 reductase and involvement of the bioactivation in the DNA damage
    • in press
    • Kumagai,Y., Arimoto,T., Shinyashiki,M., Shimojo,N., Nakai,Y., Yoshikawa,T. and Sagai,M. (1997) Generation of reactive oxygen species during interaction of diesel exhaust particles components with NADPH-cytochrome P450 reductase and involvement of the bioactivation in the DNA damage. Free Rad.Biol. Med. (in press)
    • (1997) Free Rad.Biol. Med.
    • Kumagai, Y.1    Arimoto, T.2    Shinyashiki, M.3    Shimojo, N.4    Nakai, Y.5    Yoshikawa, T.6    Sagai, M.7
  • 34
    • 0022965150 scopus 로고
    • International comparisons of mortality rates for cancer of the breast, ovary, prostate, and colon, and per capita food consumption
    • Rose,D.P, Boyar,A.P. and Wynder,E.L. (1986) International comparisons of mortality rates for cancer of the breast, ovary, prostate, and colon, and per capita food consumption. Cancer, 581, 2363-2371.
    • (1986) Cancer , vol.581 , pp. 2363-2371
    • Rose, D.P.1    Boyar, A.P.2    Wynder, E.L.3
  • 35
    • 0024151977 scopus 로고
    • Dietary fat and cancer risk: Evidence and research needs
    • Pariza,M.W. (1988) Dietary fat and cancer risk: evidence and research needs. Ann. Rev. Nutr., 8, 167-183.
    • (1988) Ann. Rev. Nutr. , vol.8 , pp. 167-183
    • Pariza, M.W.1
  • 36
    • 0020508747 scopus 로고
    • Dietary carcinogens and anticarcinogens
    • Ames,B.N. (1983) Dietary carcinogens and anticarcinogens. Science, 221, 1256-1264.
    • (1983) Science , vol.221 , pp. 1256-1264
    • Ames, B.N.1
  • 37
    • 0027501656 scopus 로고
    • Fat and calories in colon and breast cancer
    • Macrae,F.A. (1993) Fat and calories in colon and breast cancer. Preventive Med., 22, 750-766.
    • (1993) Preventive Med. , vol.22 , pp. 750-766
    • Macrae, F.A.1
  • 38
    • 0004006894 scopus 로고
    • US Government Printing Office, Washington DC
    • US Department of Health and Human Services. (1988) The surgeon general's report on nutrition and health. US Government Printing Office, Washington DC.
    • (1988) The Surgeon General's Report on Nutrition and Health
  • 39
    • 0022406947 scopus 로고
    • Effect of different levels of dietary trans fat or corn oil on azoxymethane-induced colon carcinogenesis in F 344 rats
    • Reddy,B-S., Tanaka,T. and Simi,B. (1985) Effect of different levels of dietary trans fat or corn oil on azoxymethane-induced colon carcinogenesis in F 344 rats. J. Natl Cancer Inst., 75, 791-798.
    • (1985) J. Natl Cancer Inst. , vol.75 , pp. 791-798
    • Reddy, B.-S.1    Tanaka, T.2    Simi, B.3
  • 40
    • 0021884389 scopus 로고
    • Requirement of essential fatty acids for mammary tumourigenesis in the rat
    • Ip,C., Carter,C.A. and Ip,M.M. (1985) Requirement of essential fatty acids for mammary tumourigenesis in the rat. Cancer Res., 45, 1997-2001.
    • (1985) Cancer Res. , vol.45 , pp. 1997-2001
    • Ip, C.1    Carter, C.A.2    Ip, M.M.3
  • 41
    • 0028135222 scopus 로고
    • Promoting effect of two-generation exposure to a high-fat diet on prostate carcinogenesis in ACI/Seg rats
    • Kondo,Y., Homma,Y., Aso,Y. and Kaizoe,T. (1994) Promoting effect of two-generation exposure to a high-fat diet on prostate carcinogenesis in ACI/Seg rats. Cancer Res., 23, 6129-6132.
    • (1994) Cancer Res. , vol.23 , pp. 6129-6132
    • Kondo, Y.1    Homma, Y.2    Aso, Y.3    Kaizoe, T.4
  • 42
    • 0022410160 scopus 로고
    • Dietary intervention during the post-dosing phase of L-azaserine-induced preneoplastic lesion
    • O'Conner,T.P., Roebuck,B.D. and Campbell,T.C. (1985) Dietary intervention during the post-dosing phase of L-azaserine-induced preneoplastic lesion. J. Natl Cancer Inst., 75, 955-957.
    • (1985) J. Natl Cancer Inst. , vol.75 , pp. 955-957
    • O'Conner, T.P.1    Roebuck, B.D.2    Campbell, T.C.3
  • 43
    • 0028344782 scopus 로고
    • High survival rate of hamsters given intratracheal instillation of benzo[a]pyrene and ferric oxide and kept on a high β-carotene diet
    • Wolterbeek,A.P.M., Rutten,A.A.J.J.L. and Feron,V.J. (1994) High survival rate of hamsters given intratracheal instillation of benzo[a]pyrene and ferric oxide and kept on a high β-carotene diet. Carcinogenesis, 15, 133-136.
    • (1994) Carcinogenesis , vol.15 , pp. 133-136
    • Wolterbeek, A.P.M.1    Rutten, A.A.J.J.L.2    Feron, V.J.3
  • 44
    • 0019422226 scopus 로고
    • Can dietary betacarotene materially reduce human cancer rates?
    • Peto,R., Doll,R., Buckley,J.D. and Sporn,M.B. (1981) Can dietary betacarotene materially reduce human cancer rates? Nature, 290, 201-208.
    • (1981) Nature , vol.290 , pp. 201-208
    • Peto, R.1    Doll, R.2    Buckley, J.D.3    Sporn, M.B.4
  • 45
    • 0026321076 scopus 로고
    • Plasma antioxidant vitamins and subsequent cancer mortality in the 12-year follow-up of the prospective basal study
    • Stakelin,H.B., Gey,K.F., Eichholzer,M., Ludin,E., Bernasconi,F., Thumeysen,J. and Brubacher,G. (1991) Plasma antioxidant vitamins and subsequent cancer mortality in the 12-year follow-up of the prospective basal study. Am. J. Epidemiol., 133, 766-775.
    • (1991) Am. J. Epidemiol. , vol.133 , pp. 766-775
    • Stakelin, H.B.1    Gey, K.F.2    Eichholzer, M.3    Ludin, E.4    Bernasconi, F.5    Thumeysen, J.6    Brubacher, G.7
  • 46
    • 0027223528 scopus 로고
    • Differential effects of dietary β-carotene on papilloma and carcinoma formation induced by an initiation-promotion protocol in SENCAR mouse skin
    • Chen,L.C., Sly,L., Jones,C.S., Tarone,R. and De Luca,L.M. (1993) Differential effects of dietary β-carotene on papilloma and carcinoma formation induced by an initiation-promotion protocol in SENCAR mouse skin. Carcinogenesis, 14, 713-717.
    • (1993) Carcinogenesis , vol.14 , pp. 713-717
    • Chen, L.C.1    Sly, L.2    Jones, C.S.3    Tarone, R.4    De Luca, L.M.5
  • 47
    • 0024539095 scopus 로고
    • Dietary β-carotene in rat models of gastrointestinal cancer
    • Jones,R.C., Sugie,S., Braley,J. and Weisburger,J.H. (1989) Dietary β-carotene in rat models of gastrointestinal cancer. J. Nutr., 119, 508-514.
    • (1989) J. Nutr. , vol.119 , pp. 508-514
    • Jones, R.C.1    Sugie, S.2    Braley, J.3    Weisburger, J.H.4
  • 48
    • 0023180765 scopus 로고
    • Protective effect of β-carotene against colon tumours in mice
    • Temple,N.J. and Basu,T.K. (1987) Protective effect of β-carotene against colon tumours in mice. J. Natl. Cancer Inst., 78, 1211-1214.
    • (1987) J. Natl. Cancer Inst. , vol.78 , pp. 1211-1214
    • Temple, N.J.1    Basu, T.K.2
  • 49
    • 0024592332 scopus 로고
    • Free radicals formation by antitumour quinones
    • Powis,G. (1989) Free radicals formation by antitumour quinones. Free Radical Biol. Med., 6, 63-101.
    • (1989) Free Radical Biol. Med. , vol.6 , pp. 63-101
    • Powis, G.1
  • 50
    • 0024539206 scopus 로고
    • Free radicals in anticancer drug pharmacology
    • Sinha,B.K. (1989) Free radicals in anticancer drug pharmacology. Chem. Biol. Interact., 69, 239-317.
    • (1989) Chem. Biol. Interact. , vol.69 , pp. 239-317
    • Sinha, B.K.1
  • 52
    • 0010607277 scopus 로고
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancer in male smokers
    • The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study Group (1994) The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancer in male smokers. New Engl J. Med., 330, 1029-1035.
    • (1994) New Engl J. Med. , vol.330 , pp. 1029-1035
  • 55
    • 0025095270 scopus 로고
    • Concentration- And time-dependent formation of DNA adducts in lungs of rats exposed diesel exhaust
    • Bound,J.A., Maudely,J.L. and Wolff,R.K. (1990) Concentration- and time-dependent formation of DNA adducts in lungs of rats exposed diesel exhaust. Toxicology, 60, 127-135.
    • (1990) Toxicology , vol.60 , pp. 127-135
    • Bound, J.A.1    Maudely, J.L.2    Wolff, R.K.3


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