The intrastriatal injection of thrombin in rat induced a retrograde apoptotic degeneration of nigral dopaminergic neurons through synaptic elimination

Journal of Neurochemistry

Volumn 105, Issue 3, 2008, Pages 750-762

  Herrera, Antonio J ^a   De Pablos, Rocío M ^a   Carreño Müller, Eloisa ^a   Villarán, Ruth F ^a   Venero, José L ^a   Tomás Camardiel, Mayka ^a   Cano, Josefina ^a   Machado, Alberto ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Haemorrhage; Neuronal death; Parkinson's disease; Retrograde; Striatum; Substantia nigra

Indexed keywords

ALPHA SYNUCLEIN; BRAIN PROTEIN; GLUTAMATE DECARBOXYLASE 67; PROTEINASE ACTIVATED RECEPTOR 4; SYNAPSE VESICLE PROTEIN 2; THROMBIN; THROMBIN RECEPTOR; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC ACTIVITY; DOPAMINERGIC NERVE CELL; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NERVE DEGENERATION; NONHUMAN; ONCOGENE C FOS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SUBSTANTIA NIGRA; SYNAPSE VESICLE; SYNAPTIC TRANSMISSION; UPREGULATION;

ANIMALS; APOPTOSIS; CORPUS STRIATUM; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; GLUTAMATE DECARBOXYLASE; MEMBRANE GLYCOPROTEINS; NERVE TISSUE PROTEINS; NEURAL PATHWAYS; NEUROTOXINS; PARKINSON DISEASE; PRESYNAPTIC TERMINALS; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; RECEPTORS, THROMBIN; RETROGRADE DEGENERATION; STILBAMIDINES; SUBSTANTIA NIGRA; SYNAPSES; SYNAPTIC VESICLES; SYNAPTOPHYSIN; THROMBIN; TYROSINE 3-MONOOXYGENASE;

RATTUS;

EID: 42449162417     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.05170.x     Document Type: Article

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