Neurodegeneration of substantia nigra accompanied with macrophage/microglia infiltration after intrastriatal hemorrhage

Neuroscience Research

Volumn 46, Issue 3, 2003, Pages 289-298

  Imamura, Nobuki ^a   Hida, Hideki ^a,b   Aihara, Noritaka ^a,b   Ishida, Kazuto ^a   Kanda, Yoshie ^a   Nishino, Hitoo ^a,b   Yamada, Kazuo ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b Japan Ministry of Education Culture Sports Science and Technology   (Japan)

Author keywords

Brain derived neurotrophic factor (BDNF); Intracerebral hemorrhage; Macrophage microglia; Neurodegenaration; p38 mitogen activated protein kinase (MAPK); Substantia nigra

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HEMORRHAGE; BRAIN NERVE CELL; BRAIN REGION; CELL INFILTRATION; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOREACTIVITY; MACROPHAGE; MALE; MICROGLIA; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; STATISTICAL SIGNIFICANCE; SUBSTANTIA NIGRA;

EID: 0037834431     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(03)00065-8     Document Type: Article

References (36)

1. Altumbabic M., Peeling J., Del Bigio M.R. Intracerebral hemorrhage in the rat: effects of hematoma aspiration. Stroke. 29:1998;1917-1922. discussion 1922-1923.
2. Batchelor P.E., Liberatore G.T., Wong J.Y., Porritt M.J., Frerichs F., Donnan G.A., Howells D.W. Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. J. Neurosci. 19:1999;1708-1716.
3. Batchelor P.E., Liberatore G.T., Porritt M.J., Donnan G.A., Howells D.W. Inhibition of brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor expression reduces dopaminergic sprouting in the injured striatum. Eur. J. Neurosci. 12:2000;3462-3468.
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
5. Brown R.D., Whisnant J.P., Sicks J.D., O'Fallon W.M., Wiebers D.O. Stroke incidence, prevalence, and survival: secular trends in Rochester, Minnesota, through 1989. Stroke. 27:1996;373-380.
6. Chesney J.A., Kondoh T., Conrad J.A., Low W.C. Collagenase-induced intrastriatal hemorrhage in rats results in long-term locomotor deficits. Stroke. 26:1995;312-316. discussion 317.
7. Cho S., Kim Y., Cruz M.O., Park E.M., Chu C.K., Song G.Y., Joh T.H. Repression of proinflammatory cytokine and inducible nitric oxide synthase (NOS2) gene expression in activated microglia by N-acetyl-O-methyldopamine: protein kinase A-dependent mechanism. Glia. 33:2001;324-333.
8. Daverat P., Castel J.P., Dartigues J.F., Orgogozo J.M. Death and functional outcome after spontaneous intracerebral hemorrhage. A prospective study of 166 cases using multivariate analysis. Stroke. 22:1991;1-6.
9. Del Bigio M.R., Yan H.J., Buist R., Peeling J. Experimental intracerebral hemorrhage in rats. Magnetic resonance imaging and histopathological correlates. Stroke. 27:1996;2312-2319. discussion 2319-2320.
10. Dihne M., Block F. Focal ischemia induces transient expression of IL-6 in the substantia nigra pars reticulata. Brain Res. 889:2001;165-173.
11. Elkabes S., DiCicco-Bloom E.M., Black I.B. Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function. J. Neurosci. 16:1996;2508-2521.
12. Garcia J.H., Anderson M.L. Circulatory disorders and their effects on the brain. Davis R.L., Robertson D.M. Textbook of Neuropathology. second ed:1991;621-718 Williams and Wilkins, Baltimore.
13. Inagawa T., Takechi A., Yahara K., Saito J., Moritake K., Kobayashi S., Fujii Y., Sugimura C. Primary intracerebral and aneurysmal subarachnoid hemorrhage in Izumo City, Japan. Part I: incidence and seasonal and diurnal variations. J. Neurosurg. 93:2000;958-966.
14. Inagawa T., Shibukawa M., Inokuchi F., Tokuda Y., Okada Y., Okada K. Primary intracerebral and aneurysmal subarachnoid hemorrhage in Izumo City, Japan. Part II: management and surgical outcome. J. Neurosurg. 93:2000;967-975.
15. Kataoka K., Hayakawa T., Yamada K., Mushiroi T., Kuroda R., Mogami H. Neuronal network disturbance after focal ischemia in rats. Stroke. 20:1989;1226-1235.
16. Korematsu K., Goto S., Nagahiro S., Inoue N., Oyama T., Yamada K., Ushio Y. Change of phosphotyrosine immunoreactivity on microglia in the rat substantia nigra following striatal ischemic injury. Glia. 13:1995;147-153.
17. Lan H.Y., Mu W., Nikolic-Paterson D.J., Atkins R.C. A novel, simple, reliable, and sensitive method for multiple immunoenzyme staining use of microwave oven heating to block anti-body cross-reactivity and retrieve antigens. J. Histochem. Cytochem. 43:1995;97-102.
18. Lindsay R.M., Altar C.A., Cedarbaum J.M., Hyman C., Wiegand S.J. The therapeutic potential of neurotrophic factors in the treatment of Parkinson's disease. Exp. Neurol. 124:1993;103-118.
19. Maruyama M., Sudo T., Kasuya Y., Shiga T., Hu B., Osada H. Immunolocalization of p38 MAP kinase in mouse brain. Brain Res. 887:2000;350-358.
20. McMillian M.K., Vainio P.J., Tuominen R.K. Role of protein kinase C in microglia-induced neurotoxicity in mesencephalic cultures. J. Neuropathol. Exp. Neurol. 56:1997;301-307.
21. Mogi M., Togari A., Kondo T., Mizuno Y., Komure O., Kuno S., Ichinose H., Nagatsu T. Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease. Neurosci. Lett. 270:1999;45-48.
22. Nagata K., Takei N., Nakajima K., Saito H., Kohsaka S. Microglial conditioned medium promotes survival and development of cultured mesencephalic neurons from embryonic rat brain. J. Neurosci. Res. 34:1993;357-363.
23. Nakajima K., Nagata K., Kohsaka S. Plasminogen mediates an interaction between microglia and dopaminergic neurons. Eur. Neurol. 34:1994;10-16.
24. Nakajima K., Honda S., Tohyama Y., Imai Y., Kohsaka S., Kurihara T. Neurotrophin secretion from cultured microglia. J. Neurosci. Res. 65:2001;322-331.
25. Nakane M., Teraoka A., Asato R., Tamura A. Degeneration of the ipsilateral substantia nigra following cerebral infarction in the striatum. Stroke. 23:1992;328-332.
26. Peeling J., Del Bigio M.R., Corbett D., Green A.R., Jackson D.M. Efficacy of disodium 4-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (NXY-059), a free radical trapping agent, in a rat model of hemorrhagic stroke. Neuropharmacology. 40:2001;433-439.
27. Rosenberg G.A., Mun-Bryce S., Wesley M., Kornfeld M. Collagenase-induced intracerebral hemorrhage in rats. Stroke. 21:1990;801-807.
28. Seroogy K.B., Lundgren K.H., Tran T.M., Guthrie K.M., Isackson P.J., Gall C.M. Dopaminergic neurons in rat ventral midbrain express brain-derived neurotrophic factor and neurotrophin-3 mRNAs. J. Comp. Neurol. 342:1994;321-334.
29. Shimojo M., Nakajima K., Takei N., Hamanoue M., Kohsaka S. Production of basic fibroblast growth factor in cultured rat brain microglia. Neurosci. Lett. 123:1991;229-231.
30. Sinar E.J., Mendelow A.D., Graham D.I., Teasdale G.M. Experimental intracerebral hemorrhage: effects of a temporary mass lesion. J. Neurosurg. 66:1987;568-576.
31. Tamura A., Kirino T., Sano K., Takagi K., Oka H. Atrophy of the ipsilateral substantia nigra following middle cerebral artery occlusion in the rat. Brain Res. 510:1990;154-157.
32. Tamura A., Kirino T., Sano K., Takagi K., Oka H. Atrophy of the ipsilateral substantia nigra following middle cerebral artery occlusion in the rat. Brain Res. 510:1990;154-157.
33. Tamura A., Tahira Y., Nagashima H., Kirino T., Gotoh O., Hojo S., Sano K. Thalamic atrophy following cerebral infarction in the territory of the middle cerebral artery. Stroke. 22:1991;615-618.
34. Vaca K., Wendt E. Divergent effects of astroglial and microglial secretions on neuron growth and survival. Exp. Neurol. 118:1992;62-72.
35. Walton K.M., DiRocco R., Bartlett B.A., Koury E., Marcy V.R., Jarvis B., Schaefer E.M., Bhat R.V. Activation of p38MAPK in microglia after ischemia. J. Neurochem. 70:1998;1764-1767.
36. Yang G.Y., Betz A.L., Chenevert T.L., Brunberg J.A., Hoff J.T. Experimental intracerebral hemorrhage: relationship between brain edema, blood flow, and blood-brain barrier permeability in rats. J. Neurosurg. 81:1994;93-102.