A spoke in the wheel: Calcium spikes disrupt yeast cell cycle

Cell Cycle

Volumn 7, Issue 7, 2008, Pages 870-873

  Zhang, Yong Qiang ^a   Rao, Rajini ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antifungal; Calcineurin; Calcium signaling; Cell cycle; MAP kinase; Swe1

Indexed keywords

AMIODARONE; CALCINEURIN; CALCIUM;

CALCIUM SIGNALING; CELL CYCLE; CELL CYCLE REGULATION; NONHUMAN; NUTRIENT; REVIEW; STRESS; YEAST CELL;

SACCHAROMYCES CEREVISIAE;

EID: 42449143446     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.7.7.5616     Document Type: Review

References (47)

1. Bonilla M, Cunningham KW. Mitogen-activated protein kinase stimulation of Ca(2+) signaling is required for survival of endoplasmic reticulum stress in yeast. Mol Biol Cell 2003; 14:4296-305.
2. 2+ transient activates calcineurin signaling to mediate ion homeostasis and salt tolerance of Saccharomyces cerevisiae. J Biol Chem 2002; 277:33075-80.
3. Viladevall L, Serrano R, Ruiz A, Domenech G, Giraldo J, Barcelo A, Arino J. Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae. J Biol Chem 2004; 279:43614-24.
4. 2+]i in single Saccharomyces cerevisiae cells with imaging of fura-2. J Biol Chem 1990; 265:13391-9.
5. Cyert MS. Genetic analysis of calmodulin and its targets in Saccharomyces cerevisiae. Annu Rev Genet 2001; 35:647-72.
6. Cyert MS. Calcineurin signaling in Saccharomyces cerevisiae: how yeast go crazy in response to stress. Biochem Biophys Res Commun 2003; 311:1143-50.
7. 2+ ATPases. J Cell Biol 1994; 124:351-63.
8. 2+ ATPases in Saccharomyces cerevisiae. Mol Cell Biol 1996; 16:2226-37.
9. 2+ exchangers. Mol Cell Biol 1996; 16:3730-41.
10. + pump in the yeast plasma membrane. Embo J 1995; 14:3870-82.
11. Haro R, Garciadeblas B, Rodriguez-Navarro A. A novel P-type ATPase from yeast involved in sodium transport. FEBS Lett 1991; 291:189-91.
12. Klis FM, Mol P, Hellingwerf K, Brul S. Dynamics of cell wall structure in Saccharomyces cerevisiae. FEMS Microbiol Rev 2002; 26:239-56.
13. Mendenhall MD, Hodge AE. Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 1998; 62:1191-243.
14. Loog M, Morgan DO. Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates. Nature 2005; 434:104-8.
15. Sia RA, Herald HA, Lew DJ. Cdc28 tyrosine phosphorylation and the morphogenesis checkpoint in budding yeast. Mol Biol Cell 1996; 7:1657-66.
16. La Valle R, Wittenberg C. A role for the Swe1 checkpoint kinase during filamentous growth of Saccharomyces cerevisiae. Genetics 2001; 158:549-62.
17. Alexander MR, Tyers M, Perret M, Craig BM, Fang KS, Gustin MC. Regulation of cell cycle progression by Swe1p and Hog1p following hypertonic stress. Mol Biol Cell 2001; 12:53-62.
18. 1 cell cycle delay and downregulation of Cln3/Cdc28 activity in Saccharomyces cerevisiae. Mol Microbiol 2001; 39:1022-35.
19. Clotet J, Posas F. Control of cell cycle in response to osmostress: lessons from yeast. Methods Enzymol 2007; 428:63-76.
20. Hohmann S. Osmotic stress signaling and osmoadaptation in yeasts. Microbiol Mol Biol Rev 2002; 66:300-72.
21. Gupta SS, Ton VK, Beaudry V, Rulli S, Cunningham K, Rao R. Antifungal activity of amiodarone is mediated by disruption of calcium homeostasis. J Biol Chem 2003; 278:28831-9.
22. Doggrell SA. Amiodarone - waxed and waned and waxed again. Expert Opin Pharmacother 2001; 2:1877-90.
23. Stevenson WG, Tedrow U. Management of atrial fibrillation in patients with heart failure. Heart Rhythm 2007; 4:28-30.
24. Antunes-Madeira MC, Videira RA, Madeira VM. Cholesterol modulates amiodarone-membrane interactions in model and native membranes. Appl Biochem Biotechnol 2002; 97:23-32.
25. Rosa SM, Antunes-Madeira MC, Matos MJ, Jurado AS, Madeira VM. Lipid composition and dynamics of cell membranes of Bacillus stearothermophilus adapted to amiodarone. Biochim Biophys Acta 2000; 1487:286-95.
26. Courchesne WE. Characterization of a novel, broad-based fungicidal activity for the antiarrhythmic drug amiodarone. J Pharmacol Exp Ther 2002; 300:195-9.
27. Benaim G, Sanders JM, Garcia-Marchan Y, Colina C, Lira R, Caldera AR, Payares G, Sanoja C, Burgos JM, Leon-Rossell A, Concepcion JL, Schijman AG, Levin M, Oldfield E, Urbina JA. Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole. J Med Chem 2006; 49:892-9.
28. Courchesne WE, Ozturk S. Amiodarone induces a caffeine-inhibited, MID1-depedent rise in free cytoplasmic calcium in Saccharomyces cerevisiae. Mol Microbiol 2003; 47:223-34.
29. Pozniakovsky AI, Knorre DA, Markova OV, Hyman AA, Skulachev VP, Severin FF. Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast. J Cell Biol 2005; 168:257-69.
30. Muend S, Rao R. Fungicidal activity of amiodarone is tightly coupled to calcium influx. FEMS Yeast Res 2008; In press. Published online 22 Feb, 2008. doi:10.1111/j.1567-1364.2008.00354.x
31. Zhang YQ, Rao R. Global disruption of cell cycle progression and nutrient response by the antifungal agent amiodarone. J Biol Chem 2007; 282:37844-53.
32. Yoshimoto H, Saltsman K, Gasch AP, Li HX, Ogawa N, Botstein D, Brown PO, Cyert MS. Genome-wide analysis of gene expression regulated by the calcineurin/Crz1p signaling pathway in Saccharomyces cerevisiae. J Biol Chem 2002; 277:31079-88.
33. Mizunuma M, Hirata D, Miyahara K, Tsuchiya E, Miyakawa T. Role of calcineurin and Mpk1 in regulating the onset of mitosis in budding yeast. Nature 1998; 392:303-6.
34. Gasch AP, Huang M, Metzner S, Botstein D, Elledge SJ, Brown PO. Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. Mol Biol Cell 2001; 12:2987-3003.
35. Martegani E, Baroni MD, Frascotti G, Alberghina L. Molecular cloning and transcriptional analysis of the start gene CDC25 of Saccharomyces cerevisiae. Embo J 1986; 5:2363-9.
36. Santangelo GM. Glucose signaling in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 2006; 70:253-82.
37. Thevelein JM, de Winde JH. Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 1999; 33:904-18.
38. Gorner W, Durchschlag E, Martinez Pastor MT, Estruch F, Ammerer G, Hamilton B, Ruis H, Schuller C. Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Genes Dev 1998; 12:586-97.
39. Hall DD, Markwardt DD, Parviz F, Heideman W. Regulation of the Cln3-Cdc28 kinase by cAMP in Saccharomyces cerevisiae. Embo J 1998; 17:4370-8.
40. Reinders A, Burckert N, Boller T, Wiemken A, De Virgilio C. Saccharomyces cerevisiae cAMP-dependent protein kinase controls entry into stationary phase through the Rim15p protein kinase. Genes Dev 1998; 12:2943-55.
41. Stuart D, Wittenberg C. CLN3, not positive feedback, determines the timing of CLN2 transcription in cycling cells. Genes Dev 1995; 9:2780-94.
42. Dirick L, Bohm T, Nasmyth K. Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae. Embo J 1995; 14:4803-13.
43. Ma XJ, Lu Q, Grunstein M. A search for proteins that interact genetically with histone H3 and H4 amino termini uncovers novel regulators of the Swe1 kinase in Saccharomyces cerevisiae. Genes Dev 1996; 10:1327-40.
44. 2 arrest essential for cell survival at high osmolarity. Embo J 2006; 25:2338-46.
45. Ciliberto A, Novak B, Tyson JJ. Mathematical model of the morphogenesis checkpoint in budding yeast. J Cell Biol 2003; 163:1243-54.
46. Cid VJ, Shulewitz MJ, McDonald KL, Thorner J. Dynamic localization of the Swe1 regulator Hsl7 during the Saccharomyces cerevisiae cell cycle. Mol Biol Cell 2001; 12:1645-69.
47. 2/M cell cycle regulation. Biosci Biotechnol Biochem 2007; 71:633-45.