Antifungal activity of amiodarone is mediated by disruption of calcium homeostasis

Journal of Biological Chemistry

Volumn 278, Issue 31, 2003, Pages 28831-28839

  Gupta, Soma Sen ^a,b   Ton, Van Khue ^a   Beaudry, Veronica ^a   Rulli, Samuel ^a   Cunningham, Kyle ^a   Rao, Rajini ^a,c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CALCIUM; FUNGICIDES; GENETIC ENGINEERING; TOXICITY;

HYPERSENSITIVITY;

DRUG PRODUCTS;

AEQUORIN; AMIODARONE; ANTIFUNGAL AGENT; CALCINEURIN; CALCIUM ION; CARRIER PROTEIN; FLUCONAZOLE; MICONAZOLE; PROTEIN CCH1; PROTEIN MID1; PROTEIN PMC1; PROTEIN PMR1; PROTEIN VCX1; PROTEIN YVC1; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CELL VACUOLE; DELETION MUTANT; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; DRUG SENSITIVITY; FUNGAL STRAIN; FUNGICIDAL ACTIVITY; GENOME; LUMINESCENCE; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

AMIODARONE; ANTIFUNGAL AGENTS; CALCINEURIN; CALCIUM; CALCIUM CHANNELS; CALCIUM-BINDING PROTEINS; CALCIUM-TRANSPORTING ATPASES; DRUG SYNERGISM; FLUCONAZOLE; GENE DELETION; HOMEOSTASIS; MICONAZOLE; MOLECULAR CHAPERONES; MUTATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0041706252     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303300200     Document Type: Article

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