Natural chondroitin sulphates increase aggregation of proteoglycan complexes and decrease adamts-5 expression in interleukin 1β-treated chondrocytes

Annals of the Rheumatic Diseases

Volumn 67, Issue 5, 2008, Pages 696-702

  Tahiri, K ^a   Korwin Zmijowska, C ^a   Richette, P ^a   Heraud F ^b   Chevalier, X ^c   Savouret, J F ^a   Corvol, M T ^a  

^a INSERM   (France)

^b Laboratoires Genevrier   (France)

^c HENRI MONDOR HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN 4; A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN 5; ADAM PROTEIN; CHONDROITIN SULFATE; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; PROTEOGLYCAN; SEPHAROSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL AGGREGATION; CELL CULTURE; CHROMATOGRAPHY; COMPLEX FORMATION; CONTROLLED STUDY; DRUG MECHANISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ZYMOGRAPHY;

ADAM PROTEINS; ANIMALS; BLOTTING, WESTERN; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; CHONDROITIN SULFATES; CHROMATOGRAPHY, GEL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GELATIN; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 1; PROCOLLAGEN N-ENDOPEPTIDASE; PROTEOGLYCANS; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 42449104811     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2007.078600     Document Type: Article

References (42)

1. Benya PD, Padilla SR. Modulation of the rabbit chondrocyte phenotype by retinoic acid terminates type II collagen synthesis without inducing type I collagen: the modulated phenotype differs from that produced by subculture. Dev Biol 1986;118:296-305.
2. Dudhia J. Aggrecan, aging and assembly in articular cartilage. Cell Mol Life Sci 2005;62:2241-56.
3. Platt D, Bird JL, Bayliss MT. Ageing of equine articular cartilage: structure and composition of aggrecan and decorin. Equine Vet 1998;30:43-52.
4. Wells T, Davidson C, Morgelin M, Bird JL, Bayliss MT, Dudhia J. Age-related changes in the composition, the molecular stoichiometry and the stability of proteoglycan aggregates extracted from human articular cartilage. Biochem J 2003;370:69-79.
5. Buckwalter JA, Roughley PJ, Rosenberg LC. Age-related changes in cartilage proteoglycans: quantitative electron microscopic studies. Microsc Res Tech 1994;28:398-408.
6. Verbruggen G, Cornelissen M, Almqvist KF, Wang L, Elewaut O, Broddelez C, et al. Influence of aging on the synthesis and morphology of the aggrecans synthesized by differentiated human articular chondrocytes. Osteoarthritis Cartilage 2000;8:170-9.
7. Caterson B, Flannery CR, Hughes CE, Little CB. Mechanisms involved in cartilage proteoglycan catabolism. Matrix Biol 2000;19:333-44.
8. Lark MW, Bayne EK, Flanagan J, Harper CF, Hoerrner LA, Hutchinson NI, et al. Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints. J Clin Invest 1997;100:93-106.
9. Stanton H, Rogerson FM, East CJ, Golub SB, Lawlor KE, Meeker CT, et al. ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature 2005;434:648-52.
10. Michel BA, Stucki G, Frey D, De Vathaire F, Vignon E, Bruehlmann P, et al. Chondroitins 4 and 6 sulfate in osteoarthritis of the knee: a randomized, controlled trial. Arthritis Rheum 2005;2:779-86.
11. Verbruggen G, Cornelissen M, Elewaut D, Broddelez C, De Ridder L, Veys EM. Influence of polysulfated polysaccharides on aggrecans synthesized by differentiated human articular chondrocytes. J Rheumatol 1999;26:1663-71.
12. Bassleer CT, Combal JP, Bougaret S, Malaise M. Effects of chondroitin sulfate and interleukin-1β on human articular chondrocytes cultivated in clusters. Osteoarthritis Cartilage 1998;6:196-204.
13. Nerucci F, Fioravanti A, Cicero MR, Collodel G, Marcolongo R. Effects of chondroitin sulfate and interleukin-1β on human chondrocyte cultures exposed to pressurization: a biochemical and morphological study. Osteoarthritis Cartilage 2000;8:279-87.
14. Marossy K. Interaction of the chymotrypsin- and elastase-like enzymes of the human granulocyte with glycosaminoglycans. Biochim Biophys Acta 1981;659:351-61.
15. Baici A, Lang A. Cathepsin B secretion by rabbit articular chondrocytes. Modulation by cycloheximide and glycosaminoglycans. Cell Tissue Res 1990;259:567-73.
16. Richette P, Dumontier MF, Francois M, Tsagris L, Korwin-Zmijowska C, Rannou F, et al. Dual effects of 17β-oestradiol on interleukin 1β-induced proteoglycan degradation in chondrocytes. Ann Rheum Dis 2004;63:191-9.
17. Kapuscinski J, Skoczylas B. Simple and rapid fluorimetric method for DNA microassay. Anal Biochem 1977;83:252-7.
18. Francois M, Richette P, Tsagris L, Raymondjean M, Fulchignoni-Lataud MC, Forest C, et al. Peroxisome proliferator-activated receptor-gamma down-regulates chondrocyte matrix metalloproteinase-1 via a novel composite element. J Biol Chem 2004;279:28411-18.
19. Francois M, Richette P, Tsagris L, Fitting C, Lemay C, Benallaoua M, et al. Activation of the peroxisome proliferator-activated receptor alpha pathway potentiates interleukin-1 receptor antagonist production in cytokine-treated chondrocytes. Arthritis Rheum 2006;54:1233-45.
20. Wang L, Wang J, Almqvist KF, Veys EM, Verbruggen G. Influence of polysulphated polysaccharides and hydrocortisone on the extracellular matrix metabolism of human articular chondrocytes in vitro. Clin Exp Rheumatol 2002;20:669-76.
21. Nishikawa H, Mori I, Umemoto J. Influences of sulfated glycosaminoglycans on biosynthesis of hyaluronic acid in rabbit knee synovial membrane. Arch Biochem Biophys 1985;240:146-53.
22. Mort JS, Billington CJ. Articular cartilage and changes in arthritis: matrix degradation. Arthritis Res 2001;3:337-41.
23. Struglics A, Larsson S, Pratta MA, Kumar S, Lark MW, Lohmander LS. Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase and matrix metalloproteinase-generated aggrecan fragments. Osteoarthritis Cartilage 2006;14:101-13.
24. Little CB, Hughes CE, Curtis CL, Janusz MJ, Bohne R, Wang-Weigand S, et al. Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation. Matrix Biol 2002;21:271-88.
25. Sternlicht MD, Werb Z. How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 2001;17:463-516.
26. Lohmander LS, Neame PJ, Sandy JD. The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis. Arthritis Rheum 1993;36:1214-22.
27. Sandy JD, Flannery CR, Neame PJ, Lohmander LS. The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain. J Clin Invest 1992;89:1512-16.
28. Sandy JD, Neame PJ, Boynton RE, Flannery CR. Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain. J Biol Chem 1991;266:8683-5.
29. Collins-Racie LA, Flannery CR, Zeng W, Corcoran C, Annis-Freeman B, Agostino MJ, et al. ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage. Matrix Biol 2004;23:219- 30.
30. Kuno K, Okada Y, Kawashima H, Nakamura H, Miyasaka M, Ohno H, et al. ADAMTS-1 cleaves a cartilage proteoglycan, aggrecan. FEBS Lett 2000;478:241-5.
31. Rodriguez-Manzaneque JC, Westling J, Thai SN, Lugue A, Knauper V, Murphy G, et al. ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors. Biochem Biophys Res Commun 2002;293:501-8.
32. Abbaszade I, Liu RQ, Yang F, Rosenfeld SA, Ross OH, Link JR, et al. Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family. J Biol Chem 1999;274:23443-50.
33. Tortorella MD, Burn TC, Pratta MA, Abbaszade I, Hollis JM, Liu R, et al. Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins. Science 1999;284:1664-6.
34. Glasson SS, Askew R, Sheppard B, Carito B, Blanchet T, Ma HL, et al. Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature 2005;434:644-8.
35. Glasson SS, Askew R, Sheppard B, Carito BA, Blanchet T, Ma HL, et al. Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice. Arthritis Rheum 2004;50:2547-58.
36. Vankemmelbeke MN, Holen I, Wilson AG, Ilic MZ, Handley CJ, Kelner GS, et al. Expression and activity of ADAMTS-5 in synovium. Eur J Biochem 2001;268:1259-68.
37. Sugimoto K, Takahashi M, Yamamoto Y, Shimada K, Tanzawa K. Identification of aggrecanase activity in medium of cartilage culture. J Riochem (Tokyo) 1999;126:449-55.
38. Stephens RS, Fawaz FS, Kennedy KA, Koshiyama K, Nichols B, van Ooij C, et al. Eukaryotic cell uptake of heparin-coated microspheres: a model of host cell invasion by Chlamydia trachomatis. Infect Immun 2000;68:1080-5.
39. Dudas J, Ramadori G, Knittel T, Neubauer K, Raddatz D, Egedy K, et al. Effect of heparin and liver heparan sulphate on interaction of HepG2-derived transcription factors and their cis-acting elements: altered potential of hepatocellular carcinoma heparan sulphate. Biochem J 2000;350:245-51.
40. Tebo JM, Datta S, Kishore R, Kolosov M, Major JA, Ohmori Y, et al. Interleukin-1-mediated stabilization of mouse KC mRNA depends on sequences in both 5′- and 3′-untranslated regions. J Biol Chem 2000;275:12987-93.
41. Vincenti MP. The matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) genes. Transcriptional and posttranscriptional regulation, signal transduction and cell-type-specific expression. Methods Mol Biol 2001;151:121-48.
42. Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, et al. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J 1999;18:4969-80.