LIGR, a protease-activated receptor-2-derived peptide, enhances skin pigmentation without inducing inflammatory processes

Pigment Cell and Melanoma Research

Volumn 21, Issue 2, 2008, Pages 172-183

  Lin, Connie B ^a   Chen, Nannan ^a   Scarpa, Richard ^a,b   Guan, Fei ^a   Babiarz Magee, Laura ^a   Liebel, Frank ^a   Li, Wen Hwa ^a   Kizoulis, Menas ^a   Shapiro, Stanley ^a   Seiberg, Miri ^a  

^a JOHNSON AND JOHNSON   (United States)

^b Ernst and Young   (United States)

Author keywords

Darkening; Keratinocytes; LIGR; PAR 2; Phagocytosis; Rho GTP; Skin pigmentation; Sunless tanning

Indexed keywords

CYCLIC AMP; CYCLOOXYGENASE 2; INTERLEUKIN 6; INTERLEUKIN 8; LEUCYLISOLEUCYLGLYCYLARGINYLAMIDE; MELANIN; PROSTAGLANDIN E2; PROTEINASE ACTIVATED RECEPTOR 2; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SERYLLEUCYLISOLEUCYLGLYCYLARGINYLAMIDE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; ENZYME INDUCTION; FEMALE; HUMAN; HUMAN CELL; KERATINOCYTE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SKIN COLOR; SKIN INFLAMMATION; SKIN PIGMENTATION; SWINE; ULTRAVIOLET RADIATION;

ADMINISTRATION, TOPICAL; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; FEMALE; GENE SILENCING; HUMANS; INFLAMMATION; KERATINOCYTES; MICE; MICE, SCID; PEPTIDES; PHAGOCYTOSIS; RECEPTOR, PAR-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKIN PIGMENTATION; SKIN TRANSPLANTATION; SWINE; TRANSPLANTATION, HETEROLOGOUS;

MUS;

EID: 42249089548     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2008.00441.x     Document Type: Article

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