Trypsin induces tumour necrosis factor-α secretion from a human leukemic mast cell line

Cell Biochemistry and Function

Volumn 21, Issue 2, 2003, Pages 161-167

  Kang, Ok Hwa ^a   Jeong, Hyun Ja ^a   Kim, Dae Ki ^b   Choi, Suck Chei ^c   Kim, Tae Hyun ^c   Nah, Yong Ho ^c   Kim, Hyung Min ^a   Lee, Young Mi ^a  

^a Wonkwang University   (South Korea)

^b Chonbuk National University   (South Korea)

^c Wonkwang University School of Medicine   (South Korea)

Author keywords

HMC 1; MAPK; PAR2; PAR4; TNF ; Trypsin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; MITOGEN ACTIVATED PROTEIN KINASE 1; PEPTIDE; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 4; SERYLISOLEUCYLGLYCYLLYSYLVALINAMIDE; STRESS ACTIVATED PROTEIN KINASE; TRYPSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOREGULATION; MAST CELL; MAST CELL DEGRANULATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

CELL DEGRANULATION; HUMANS; LEUKEMIA, MAST-CELL; MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTOR, PAR-2; RECEPTORS, THROMBIN; TRYPSIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0012273930     PISSN: 02636484     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbf.1014     Document Type: Article

References (30)

1. Dery O, Corvera CU, Steinhoff M, Bunnet NW. Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am J Physiol 1998; 274: C1429-C1452.
2. Steinhoff M, Vergnolle N, Young SH, et al. Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism. Nature Med 2000; 6: 151-158.
3. Chambers RC, Leoni P, Blanc-Brude OP, Wembridge DE, Laurent GJ. Thrombin is a potent inducer of connective tissue growth factor production via proteolytic activation of protease-activated receptor-1. J Biol Chem 2000; 275: 35584-35591.
4. Kawabata A, Kuroda R, Nakaya Y, Kawai K, Nishikawa H, Kawao N. Factor Xa-evoked relaxation in rat aorta: involvement of PAR-2. Biochem Biophys Res Commun 2001; 282: 432-435.
5. Lindner JR, Kahn ML, Coughlin SR, et al. Delayed onset of inflammation in protease-activated receptor-2-deficient mice. J Immunol 2000; 165: 6504-6510.
6. Lundberg AH, Eubanks JW, 3rd, Henry J, et al. Trypsin stimulates production of cytokines from peritoneal macrophages in vitro and in vivo. Pancreas 2000; 21: 41-51.
7. Koshikawa N, Nagashima Y, Miyagi Y, et al. Expression of trypsin in vascular endothelial cells. FEBS Lett 1997; 409: 442-448.
8. Koshikawa N, Hasegawa S, Nagashima Y, et al. Expression of trypsin by epithelial cells of various tissues, leukocytes, and neurons in human and mouse. Am J Pathol 1998; 153: 937-944.
9. Koshikawa N, Yasumitsu H, Umeda M, Miyazaki K. Multiple secretion of matrix serine proteinases by human gastric carcinoma cell lines. Cancer Res 1992; 52: 5046-5053.
10. Hirahara F, Miyagi Y, Miyagi E, et al. Trypsinogen expression in human ovarian carcinomas. Int J Cancer 1995; 63: 176-181.
11. Kawano N, Osawa H, Ito T, et al. Expression of gelatinase A, tissue inhibitor of metalloproteinases-2 (TIMP-2), matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemistry study. Hum Pathol 1997; 28: 613-622.
12. Koivunen E, Saksela O, Itkonen O, Osman S, Huhtala ML, Stenman UH. Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen. Int J Cancer 1991; 47: 592-596.
13. Metcalfe DD, Baram D, Mekori YA. Mast cells. Physiol Rev 1997; 77: 1033-1079.
14. Bradding P, Feather IH, Wilson S, et al. Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5, and IL-6 in human allergic mucosal inflammation. J Immunol 1993; 151: 3853-3865.
15. Nishikawa H, Kawabata A, Kuroda R, Nishida M, Kawai K. Characterization of protease-activated receptors in rat peritoneal mast cells. Jpn J Pharmacol 2000; 82: 74-77.
16. D'andrea MR, Rogahn CJ, Andrade-Gordon P. Localization of protease-activated receptors-1 and -2 in human mast cells: indications for an amplified mast cell degranulation cascade. Biotech Histochem 2000; 75: 85-90.
17. Razin E, Marx G. Thrombin-induced degranulation of cultured bone marrow-derived mast cells. J Immunol 1984; 133: 3282-3285.
18. He S, Gaca MD, Walls AF. A role for tryptase in the activation of human mast cells: modulation of histamine release by tryptase and inhibitors of tryptase. J Pharmacol Exp Ther 1998; 286: 289-297.
19. Bohm SK, Kong W, Bromme D, et al. Molecular cloning expression and potential functions of the human proteinase-activated receptor-2. Biochem J 1996; 314: 1009-1016.
20. Kahn ML, Nakanishi-Matsui M, Shapiro MJ, Ishihara H, Coughlin SR. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest 1999; 103: 879-887.
21. Lee YB, Schrader JW, Kim SU. p38 MAP kinase regulates TNF-alpha production in human astrocytes and microglia by multiple mechanisms. Cytokine 2000; 12: 874-880.
22. Napoli C, Cicala C, Wallace JL, et al. Protease-activated receptor-2 modulates myocardial ischemia-reperfusion injury in the rat heart. Proc Natl Acad Sci USA 2000; 97: 3678-3683.
23. Chinni C, de Niese MR, Jenkins AL, Pike RN, Bottomley SP, Mackie EJ. Protease-activated receptor-2 mediates proliferative responses in skeletal myoblasts. J Cell Sci 2000; 113(Pt 24): 4427-4433.
24. Kobayashi H, Shibata K, Fujie M, Terao T. Urinary trypsin inhibitor reduces the release of histamine from rat peritoneal mast cells. J Lab Clin Med 1999; 131: 375-385.
25. Vergnolle N, Hollenberg MD, Sharkey KA, Wallace JL. Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw. Br J Pharmacol 1999; 127: 1083-1090.
26. Kanke T, Macfarlane SR, Seatter MJ, et al. Proteinase-activated receptor-2-mediated activation of stress-activated protein kinases and inhibitory kappa B kinases in NCTC 2544 keratinocytes. J Biol Chem 2001; 276: 31657-31666.
27. Belham CM, Tate RJ, Scott PH, et al. Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases. Biochem J 1996; 320: 939-946.
28. Bretschneider E, Kaufmann R, Braun M, Nowak G, Glusa E, Schror K. Evidence for functionally active protease-activated receptor-4 (PAR-4) in human vascular smooth muscle cells. BrJ Pharmacol 2001; 132: 1441-1446.
29. Sabri A, Muske G, Zhang H, et al. Signaling properties and functions of two distinct cardiomyocyte protease-activated receptors. Circ Res 2000; 86: 1054-1061.
30. Furuta GT, Schmidt-Choudhury A, Wang MY, et al. Mast cell-dependent tumor necrosis factor alpha production participates in allergic gastric inflammation in mice. Gastroenterology 1997; 113: 1560-1569.