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Volumn 67, Issue 2, 2008, Pages 206-213

Nutrigenetics and CVD: What does the future hold?

Author keywords

ApoE, apoAI and PPAR polymorphisms; CVD risk; Dietary fat; Nutrigenetics

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN E; BIOLOGICAL MARKER; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

EID: 42149108476     PISSN: 00296651     EISSN: 14752719     Source Type: Journal    
DOI: 10.1017/S0029665108007040     Document Type: Conference Paper
Times cited : (29)

References (64)
  • 3
    • 1842483155 scopus 로고    scopus 로고
    • Nutritional genomics: The next frontier in the postgenomic era
    • Kaput J & Rodriguez RL (2004) Nutritional genomics: the next frontier in the postgenomic era. Physiol Genomics 16, 166-177.
    • (2004) Physiol Genomics , vol.16 , pp. 166-177
    • Kaput, J.1    Rodriguez, R.L.2
  • 4
    • 1842609791 scopus 로고    scopus 로고
    • Nutrigenomics and nutrigenetics
    • Ordovas JM & Mooser V (2004) Nutrigenomics and nutrigenetics. Curr Opin Lipidol 15, 101-108.
    • (2004) Curr Opin Lipidol , vol.15 , pp. 101-108
    • Ordovas, J.M.1    Mooser, V.2
  • 6
    • 32944481700 scopus 로고    scopus 로고
    • Perspectives on human genetic variation from the HapMap project
    • McVean G, Spencer C & Chaix R (2005) Perspectives on human genetic variation from the HapMap project. PLoS Genet 1, e54.
    • (2005) PLoS Genet , vol.1
    • McVean, G.1    Spencer, C.2    Chaix, R.3
  • 8
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM, Timpson NJ, Weedon MN et al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 316, 889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3
  • 9
    • 0033678517 scopus 로고    scopus 로고
    • Anisomastia associated with interstitial duplication of chromosome 16, mental retardation, obesity, dysmorphic facies, and digital anomalies: Molecular mapping of a new syndrome by fluorescent in situ hybridization and microsatellites to 16q13 (D16S419-D16S503)
    • Stratakis CA, Lafferty A, Taymans SE, Gafni RI, Meck JM & Blancato J (2000) Anisomastia associated with interstitial duplication of chromosome 16, mental retardation, obesity, dysmorphic facies, and digital anomalies: molecular mapping of a new syndrome by fluorescent in situ hybridization and microsatellites to 16q13 (D16S419-D16S503). J Clin Endocrinol Metab 85, 3396-3401.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3396-3401
    • Stratakis, C.A.1    Lafferty, A.2    Taymans, S.E.3    Gafni, R.I.4    Meck, J.M.5    Blancato, J.6
  • 10
    • 26444493132 scopus 로고    scopus 로고
    • Nutrigenomics and nutrigenetics: The emerging faces of nutrition
    • Mutch DM, Wahli W & Williamson G (2005) Nutrigenomics and nutrigenetics: the emerging faces of nutrition. FASEB J 19, 1602-1616.
    • (2005) FASEB J , vol.19 , pp. 1602-1616
    • Mutch, D.M.1    Wahli, W.2    Williamson, G.3
  • 11
    • 0036124659 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids in coronary heart disease: A meta-analysis of randomized controlled trials
    • Bucher HC, Hengstler P, Schindler C & Meier G (2002) N-3 polyunsaturated fatty acids in coronary heart disease: a meta-analysis of randomized controlled trials. Am J Med 112, 298-304.
    • (2002) Am J Med , vol.112 , pp. 298-304
    • Bucher, H.C.1    Hengstler, P.2    Schindler, C.3    Meier, G.4
  • 12
    • 0024363690 scopus 로고
    • Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: Diet and reinfarction trial (DART)
    • Burr L, Fehily AM, Gilbert JF, Rogers S, Holliday RM, Sweetnam PM, Elwood PC & Deadman NM (1989) Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: Diet and reinfarction trial (DART). Lancet ii, 757-761.
    • (1989) Lancet , vol.2 , pp. 757-761
    • Burr, L.1    Fehily, A.M.2    Gilbert, J.F.3    Rogers, S.4    Holliday, R.M.5    Sweetnam, P.M.6    Elwood, P.C.7    Deadman, N.M.8
  • 13
    • 0037317469 scopus 로고    scopus 로고
    • Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease
    • Kris-Etherton P, Harris W & Appel L (2003) Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Arterioscler Thromb Vasc Biol 23, E31-E42.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23
    • Kris-Etherton, P.1    Harris, W.2    Appel, L.3
  • 15
    • 3042723693 scopus 로고    scopus 로고
    • Moderate fish-oil supplementation reverses low-platelet, long-chain n-3 polyunsaturated fatty acid status and reduces plasma triacylglycerol concentrations in British Indo-Asians
    • Lovegrove JA, Lovegrove SS, Lesauvage SV, Brady LM, Saini N, Minihane AM & Williams CM (2004) Moderate fish-oil supplementation reverses low-platelet, long-chain n-3 polyunsaturated fatty acid status and reduces plasma triacylglycerol concentrations in British Indo-Asians. Am J Clin Nutr 79, 974-982.
    • (2004) Am J Clin Nutr , vol.79 , pp. 974-982
    • Lovegrove, J.A.1    Lovegrove, S.S.2    Lesauvage, S.V.3    Brady, L.M.4    Saini, N.5    Minihane, A.M.6    Williams, C.M.7
  • 16
    • 3042844199 scopus 로고    scopus 로고
    • Increased n-6 polyunsaturated fatty acids do not attenuate the effects of long-chain n-3 polyunsaturated fatty acids on insulin sensitivity or triacylglycerol reduction in Indian Asians
    • Brady LM, Lovegrove SS, Lesauvage SV, Gower BA, Minihane AM, Williams CM & Lovegrove JA (2004) Increased n-6 polyunsaturated fatty acids do not attenuate the effects of long-chain n-3 polyunsaturated fatty acids on insulin sensitivity or triacylglycerol reduction in Indian Asians. Am J Clin Nutr 79, 983-991.
    • (2004) Am J Clin Nutr , vol.79 , pp. 983-991
    • Brady, L.M.1    Lovegrove, S.S.2    Lesauvage, S.V.3    Gower, B.A.4    Minihane, A.M.5    Williams, C.M.6    Lovegrove, J.A.7
  • 17
    • 0033238035 scopus 로고    scopus 로고
    • Overexpression of apolipoprotein E3 in transgenic rabbits causes combined hyperlipidemia by stimulating hepatic VLDL production and impairing VLDL lipolysis
    • Huang Y, Ji ZS, Brecht WJ, Rall SC Jr, Taylor JM & Mahley RW (1999) Overexpression of apolipoprotein E3 in transgenic rabbits causes combined hyperlipidemia by stimulating hepatic VLDL production and impairing VLDL lipolysis. Arterioscler Thromb Vasc Biol 19, 2952-2959.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2952-2959
    • Huang, Y.1    Ji, Z.S.2    Brecht, W.J.3    Rall Jr, S.C.4    Taylor, J.M.5    Mahley, R.W.6
  • 18
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • Mahley RW (1988) Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 240, 622-630.
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 19
    • 34147170817 scopus 로고    scopus 로고
    • Apolipoprotein E genotype, cardiovascular risk and responsiveness to dietary fat manipulation
    • Minihane AM, Jofre-Monseny L, Olano-Martin E & Rimbach GH (2007) Apolipoprotein E genotype, cardiovascular risk and responsiveness to dietary fat manipulation. Proc Nutr Soc 66, 183-197.
    • (2007) Proc Nutr Soc , vol.66 , pp. 183-197
    • Minihane, A.M.1    Jofre-Monseny, L.2    Olano-Martin, E.3    Rimbach, G.H.4
  • 20
    • 0020490536 scopus 로고
    • Human apolipoprotein E (). The complete amino acid sequence
    • Rall SC Jr, Weisgraber KH & Mahley RW (1982) Human apolipoprotein E (). The complete amino acid sequence. J Biol Chem 257, 4171-4178.
    • (1982) J Biol Chem , vol.257 , pp. 4171-4178
    • Rall Jr, S.C.1    Weisgraber, K.H.2    Mahley, R.W.3
  • 21
    • 0025171570 scopus 로고
    • Apolipoprotein E distribution among human plasma lipoproteins: Role of the cysteine-arginine interchange at residue 112
    • Weisgraber KH (1990) Apolipoprotein E distribution among human plasma lipoproteins: role of the cysteine-arginine interchange at residue 112. J Lipid Res 31, 1503-1511.
    • (1990) J Lipid Res , vol.31 , pp. 1503-1511
    • Weisgraber, K.H.1
  • 23
    • 33747165894 scopus 로고    scopus 로고
    • ApoE distribution in world populations with new data from India and the UK
    • Singh P, Singh M & Mastana S (2006) ApoE distribution in world populations with new data from India and the UK. Ann Hum Biol 33, 297-308.
    • (2006) Ann Hum Biol , vol.33 , pp. 297-308
    • Singh, P.1    Singh, M.2    Mastana, S.3
  • 24
    • 3142706539 scopus 로고    scopus 로고
    • Meta-analysis: Apolipoprotein E genotypes and risk for coronary heart disease
    • Song Y, Stampfer MJ & Liu S (2004) Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease. Ann Intern Med 141, 137-147.
    • (2004) Ann Intern Med , vol.141 , pp. 137-147
    • Song, Y.1    Stampfer, M.J.2    Liu, S.3
  • 25
    • 34147170817 scopus 로고    scopus 로고
    • ApoE genotype, cardiovascular risk and responsiveness to dietary fat manipulation
    • Minihane AM, Jofre-Monseny L, Olano-Martin E & Rimbach G (2007) ApoE genotype, cardiovascular risk and responsiveness to dietary fat manipulation. Proc Nutr Soc 66, 183-197.
    • (2007) Proc Nutr Soc , vol.66 , pp. 183-197
    • Minihane, A.M.1    Jofre-Monseny, L.2    Olano-Martin, E.3    Rimbach, G.4
  • 26
    • 0031797305 scopus 로고    scopus 로고
    • Effect of apolipoprotein E polymorphism on serum lipid response to the separate modification of dietary fat and dietary cholesterol
    • Sarkkinen E, Korhonen M, Erkkila A, Ebeling T & Uusitupa M (1998) Effect of apolipoprotein E polymorphism on serum lipid response to the separate modification of dietary fat and dietary cholesterol. Am J Clin Nutr 68, 1215-1222.
    • (1998) Am J Clin Nutr , vol.68 , pp. 1215-1222
    • Sarkkinen, E.1    Korhonen, M.2    Erkkila, A.3    Ebeling, T.4    Uusitupa, M.5
  • 27
    • 0026726414 scopus 로고
    • Cholesterol absorption, elimination, and synthesis related to LDL kinetics during varying fat intake in men with different apoprotein E phenotypes
    • Miettinen TA, Gylling H, Vanhanen H & Ollus A (1992) Cholesterol absorption, elimination, and synthesis related to LDL kinetics during varying fat intake in men with different apoprotein E phenotypes. Arterioscler Thromb 12, 1044-1052.
    • (1992) Arterioscler Thromb , vol.12 , pp. 1044-1052
    • Miettinen, T.A.1    Gylling, H.2    Vanhanen, H.3    Ollus, A.4
  • 28
    • 0026604145 scopus 로고
    • Cholesterol-rich diet induced changes in plasma lipids in relation to apolipoprotein E phenotype in healthy students
    • Lehtimaki T, Moilanen T, Solakivi T, Laippala P & Ehnholm C (1992) Cholesterol-rich diet induced changes in plasma lipids in relation to apolipoprotein E phenotype in healthy students. Ann Med 24, 61-66.
    • (1992) Ann Med , vol.24 , pp. 61-66
    • Lehtimaki, T.1    Moilanen, T.2    Solakivi, T.3    Laippala, P.4    Ehnholm, C.5
  • 29
    • 0028985109 scopus 로고
    • Plasma lipids and lipoproteins response to a dietary challenge: Analysis of four candidate genes
    • Friedlander Y, Berry EM, Eisenberg S, Stein Y & Leitersdorf E (1995) Plasma lipids and lipoproteins response to a dietary challenge: analysis of four candidate genes. Clin Genet 47, 1-12.
    • (1995) Clin Genet , vol.47 , pp. 1-12
    • Friedlander, Y.1    Berry, E.M.2    Eisenberg, S.3    Stein, Y.4    Leitersdorf, E.5
  • 30
    • 0031951031 scopus 로고    scopus 로고
    • Effect of apolipoprotein E polymorphism on serum lipoprotein response to saturated fatty acids
    • Tso TK, Park S, Tsai YH, Williams G & Snook JT (1998) Effect of apolipoprotein E polymorphism on serum lipoprotein response to saturated fatty acids. Lipids 33, 139-148.
    • (1998) Lipids , vol.33 , pp. 139-148
    • Tso, T.K.1    Park, S.2    Tsai, Y.H.3    Williams, G.4    Snook, J.T.5
  • 34
    • 0025194711 scopus 로고
    • Apolipoprotein E4 homozygosity predisposes to serum cholesterol elevation during high fat diet
    • Tikkanen MJ, Huttunen JK, Ehnholm C & Pietinen P (1990) Apolipoprotein E4 homozygosity predisposes to serum cholesterol elevation during high fat diet. Arteriosclerosis 10, 285-288.
    • (1990) Arteriosclerosis , vol.10 , pp. 285-288
    • Tikkanen, M.J.1    Huttunen, J.K.2    Ehnholm, C.3    Pietinen, P.4
  • 35
    • 0026008016 scopus 로고
    • Apolipoprotein E polymorphism influences the serum cholesterol response to dietary intervention
    • Manttari M, Koskinen P, Ehnholm C, Huttunen JK & Manninen V (1991) Apolipoprotein E polymorphism influences the serum cholesterol response to dietary intervention. Metabolism 40, 217-221.
    • (1991) Metabolism , vol.40 , pp. 217-221
    • Manttari, M.1    Koskinen, P.2    Ehnholm, C.3    Huttunen, J.K.4    Manninen, V.5
  • 37
    • 0037797302 scopus 로고    scopus 로고
    • Genetic variation and the lipid response to dietary intervention: A systematic review
    • Masson LF, McNeill G & Avenell A (2003) Genetic variation and the lipid response to dietary intervention: a systematic review. Am J Clin Nutr 77, 1098-1111.
    • (2003) Am J Clin Nutr , vol.77 , pp. 1098-1111
    • Masson, L.F.1    McNeill, G.2    Avenell, A.3
  • 38
    • 0345375272 scopus 로고    scopus 로고
    • Influences of apolipoprotein E polymorphism on the response of plasma lipids to the ad libitum consumption of a high-carbohydrate diet compared with a high-monounsaturated fatty acid diet
    • Couture P, Archer WR, Lamarche B, Landry N, Deriaz O, Corneau L, Bergeron J & Bergeron N (2003) Influences of apolipoprotein E polymorphism on the response of plasma lipids to the ad libitum consumption of a high-carbohydrate diet compared with a high-monounsaturated fatty acid diet. Metabolism 52, 1454-1459.
    • (2003) Metabolism , vol.52 , pp. 1454-1459
    • Couture, P.1    Archer, W.R.2    Lamarche, B.3    Landry, N.4    Deriaz, O.5    Corneau, L.6    Bergeron, J.7    Bergeron, N.8
  • 39
    • 4744376443 scopus 로고    scopus 로고
    • The effect of dietary fat on LDL size is influenced by apolipoprotein E genotype in healthy subjects
    • Moreno JA, Perez-Jimenez F, Marin C, Gomez P, Perez-Martinez P, Moreno R, et al. (2004) The effect of dietary fat on LDL size is influenced by apolipoprotein E genotype in healthy subjects. J Nutr 134, 2517-2522.
    • (2004) J Nutr , vol.134 , pp. 2517-2522
    • Moreno, J.A.1    Perez-Jimenez, F.2    Marin, C.3    Gomez, P.4    Perez-Martinez, P.5    Moreno, R.6
  • 40
    • 33644869190 scopus 로고    scopus 로고
    • Genetic interactions with diet influence the risk of cardiovascular disease
    • Ordovas JM (2006) Genetic interactions with diet influence the risk of cardiovascular disease. Am J Clin Nutr 83, 443S-446S.
    • (2006) Am J Clin Nutr , vol.83
    • Ordovas, J.M.1
  • 41
    • 0024230807 scopus 로고
    • High density lipoprotein cholesterol and mortality. The Framingham Heart Study
    • Wilson PW, Abbott RD & Castelli WP (1988) High density lipoprotein cholesterol and mortality. The Framingham Heart Study. Arteriosclerosis 8, 737-741.
    • (1988) Arteriosclerosis , vol.8 , pp. 737-741
    • Wilson, P.W.1    Abbott, R.D.2    Castelli, W.P.3
  • 42
    • 0036136232 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: The Framingham Study
    • Ordovas JM, Corella D, Cupples LA, Demissie S, Kelleher A, Coltell O, Wilson PWF, Schaefer EJ & Tucker K (2002) Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: the Framingham Study. Am J Clin Nutr 75, 38-46.
    • (2002) Am J Clin Nutr , vol.75 , pp. 38-46
    • Ordovas, J.M.1    Corella, D.2    Cupples, L.A.3    Demissie, S.4    Kelleher, A.5    Coltell, O.6    Wilson, P.W.F.7    Schaefer, E.J.8    Tucker, K.9
  • 43
    • 0032588487 scopus 로고    scopus 로고
    • PPARgamma, the ultimate thrifty gene
    • Auwerx J (1999) PPARgamma, the ultimate thrifty gene. Diabetologia 42, 1033-1049.
    • (1999) Diabetologia , vol.42 , pp. 1033-1049
    • Auwerx, J.1
  • 44
    • 0035851187 scopus 로고    scopus 로고
    • PPARgamma: A nuclear regulator of metabolism, differentiation, and cell growth
    • Rosen ED & Spiegelman BM (2001) PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem 276, 37731-37734.
    • (2001) J Biol Chem , vol.276 , pp. 37731-37734
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 45
    • 33745214257 scopus 로고    scopus 로고
    • Energy balance and food intake: The role of PPARgamma gene polymorphisms
    • Cecil JE, Watt P, Palmer CN & Hetherington M (2006) Energy balance and food intake: the role of PPARgamma gene polymorphisms. Physiol Behav 88, 227-233.
    • (2006) Physiol Behav , vol.88 , pp. 227-233
    • Cecil, J.E.1    Watt, P.2    Palmer, C.N.3    Hetherington, M.4
  • 46
    • 0141781066 scopus 로고    scopus 로고
    • Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetes
    • Memisoglu A, Hu FB, Hankinson SE, Liu S, Meigs JB, Altshuler DM, Hunter DJ & Manson JE (2003) Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPARgamma gene and type 2 diabetes. Diabetes Care 26, 2915-2917.
    • (2003) Diabetes Care , vol.26 , pp. 2915-2917
    • Memisoglu, A.1    Hu, F.B.2    Hankinson, S.E.3    Liu, S.4    Meigs, J.B.5    Altshuler, D.M.6    Hunter, D.J.7    Manson, J.E.8
  • 47
    • 0036772369 scopus 로고    scopus 로고
    • Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population
    • Gonzalez Sanchez JL, Serrano Rios M, Fernandez Perez C, Laakso M & Martinez Larrad MT (2002) Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population. Eur J Endocrinol 147, 495-501.
    • (2002) Eur J Endocrinol , vol.147 , pp. 495-501
    • Gonzalez Sanchez, J.L.1    Serrano Rios, M.2    Fernandez Perez, C.3    Laakso, M.4    Martinez Larrad, M.T.5
  • 48
    • 4243353569 scopus 로고    scopus 로고
    • Studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: Homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome
    • Frederiksen L, Brodbaek K, Fenger M, Jorgensen T, Borch-Johnsen K, Madsbad S & Urhammer SA (2002) Studies of the Pro12Ala polymorphism of the PPAR-gamma gene in the Danish MONICA cohort: homozygosity of the Ala allele confers a decreased risk of the insulin resistance syndrome. J Clin Endocrinol Metab 87, 3989-3992.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3989-3992
    • Frederiksen, L.1    Brodbaek, K.2    Fenger, M.3    Jorgensen, T.4    Borch-Johnsen, K.5    Madsbad, S.6    Urhammer, S.A.7
  • 49
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • Altshuler D, Hirschhorn JN, Klannemark M et al. (2000) The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26, 76-80.
    • (2000) Nat Genet , vol.26 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.N.2    Klannemark, M.3
  • 50
    • 33748286941 scopus 로고    scopus 로고
    • Soriguer F, Morcillo S, Cardona F, Rojo-Martinez G, de la Cruz Almaraz M, de la Soledad Ruiz de Adana M, Olveira G, Tinahones F & Esteva I (2006) Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral insulin sensitivity in a population with a high intake of oleic acid. J Nutr 136, 2325-2330.
    • Soriguer F, Morcillo S, Cardona F, Rojo-Martinez G, de la Cruz Almaraz M, de la Soledad Ruiz de Adana M, Olveira G, Tinahones F & Esteva I (2006) Pro12Ala polymorphism of the PPARG2 gene is associated with type 2 diabetes mellitus and peripheral insulin sensitivity in a population with a high intake of oleic acid. J Nutr 136, 2325-2330.
  • 51
    • 0034745183 scopus 로고    scopus 로고
    • Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 gene is associated with increased antilipolytic insulin sensitivity
    • Stumvoll M, Wahl HG, Loblein K, Becker R, Machicao F, Jacob S & Häring H (2001) Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma2 gene is associated with increased antilipolytic insulin sensitivity. Diabetes 50, 876-881.
    • (2001) Diabetes , vol.50 , pp. 876-881
    • Stumvoll, M.1    Wahl, H.G.2    Loblein, K.3    Becker, R.4    Machicao, F.5    Jacob, S.6    Häring, H.7
  • 52
    • 0036399092 scopus 로고    scopus 로고
    • Fasting plasma free fatty acid concentrations and Pro12Ala polymorphism of the peroxisome proliferator-activated receptor (PPAR) gamma2 gene in healthy individuals
    • Vaccaro O, Mancini FP, Ruffa G et al. (2002) Fasting plasma free fatty acid concentrations and Pro12Ala polymorphism of the peroxisome proliferator-activated receptor (PPAR) gamma2 gene in healthy individuals. Clin Endocrinol (Oxf) 57, 481-486.
    • (2002) Clin Endocrinol (Oxf) , vol.57 , pp. 481-486
    • Vaccaro, O.1    Mancini, F.P.2    Ruffa, G.3
  • 53
    • 0345306138 scopus 로고    scopus 로고
    • Interaction between a peroxisome proliferator-activated receptor gamma gene polymorphism and dietary fat intake in relation to body mass
    • Memisoglu A, Hu FB, Hankinson SE, Manson JE, De Vivo I, Willett WC & Hunter DJ (2003) Interaction between a peroxisome proliferator-activated receptor gamma gene polymorphism and dietary fat intake in relation to body mass. Hum Mol Genet 12, 2923-2929.
    • (2003) Hum Mol Genet , vol.12 , pp. 2923-2929
    • Memisoglu, A.1    Hu, F.B.2    Hankinson, S.E.3    Manson, J.E.4    De Vivo, I.5    Willett, W.C.6    Hunter, D.J.7
  • 54
    • 0041630975 scopus 로고    scopus 로고
    • The PPAR-gamma P12A polymorphism modulates the relationship between dietary fat intake and components of the metabolic syndrome: Results from the Quebec Family Study
    • Robitaille J, Despres JP, Perusse L & Vohl MC (2003) The PPAR-gamma P12A polymorphism modulates the relationship between dietary fat intake and components of the metabolic syndrome: results from the Quebec Family Study. Clin Genet 63, 109-116.
    • (2003) Clin Genet , vol.63 , pp. 109-116
    • Robitaille, J.1    Despres, J.P.2    Perusse, L.3    Vohl, M.C.4
  • 56
    • 0036329369 scopus 로고    scopus 로고
    • Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study
    • Lindi VI, Uusitupa MI, Lindstrom J et al. (2002) Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study. Diabetes 51, 2581-2586.
    • (2002) Diabetes , vol.51 , pp. 2581-2586
    • Lindi, V.I.1    Uusitupa, M.I.2    Lindstrom, J.3
  • 57
    • 0035461855 scopus 로고    scopus 로고
    • Genetic variation in the peroxisome proliferator-activated receptor-gamma2 gene (Pro12Ala) affects metabolic responses to weight loss and subsequent weight regain
    • Nicklas BJ, van Rossum EF, Berman DM, Ryan AS, Dennis KE & Shuldiner AR (2001) Genetic variation in the peroxisome proliferator-activated receptor-gamma2 gene (Pro12Ala) affects metabolic responses to weight loss and subsequent weight regain. Diabetes 50, 2172-2176.
    • (2001) Diabetes , vol.50 , pp. 2172-2176
    • Nicklas, B.J.1    van Rossum, E.F.2    Berman, D.M.3    Ryan, A.S.4    Dennis, K.E.5    Shuldiner, A.R.6
  • 58
    • 0033866105 scopus 로고    scopus 로고
    • The Pro12Ala polymorphism in the peroxisome proliferatoractivated receptor gamma2 gene is not associated with postprandial responses to glucose or fat tolerance tests in young healthy subjects: The European Atherosclerosis Research Study II
    • Poirier O, Nicaud V, Cambien F & Tiret L (2000) The Pro12Ala polymorphism in the peroxisome proliferatoractivated receptor gamma2 gene is not associated with postprandial responses to glucose or fat tolerance tests in young healthy subjects: the European Atherosclerosis Research Study II. J Mol Med 78, 346-351.
    • (2000) J Mol Med , vol.78 , pp. 346-351
    • Poirier, O.1    Nicaud, V.2    Cambien, F.3    Tiret, L.4
  • 59
    • 12444344691 scopus 로고    scopus 로고
    • Impact of the Pro12Ala polymorphism of the PPAR-gamma2 gene on serum triacylglycerol response to n-3 fatty acid supplementation
    • Lindi V, Schwab U, Louheranta A et al. (2003) Impact of the Pro12Ala polymorphism of the PPAR-gamma2 gene on serum triacylglycerol response to n-3 fatty acid supplementation. Mol Genet Metab 79, 52-60.
    • (2003) Mol Genet Metab , vol.79 , pp. 52-60
    • Lindi, V.1    Schwab, U.2    Louheranta, A.3
  • 60
    • 0033779728 scopus 로고    scopus 로고
    • PPAR gamma and the treatment of insulin resistance
    • Olefsky JM & Saltiel AR (2000) PPAR gamma and the treatment of insulin resistance. Trends Endocrinol Metab 11, 362-368.
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 362-368
    • Olefsky, J.M.1    Saltiel, A.R.2
  • 63
    • 27144499158 scopus 로고    scopus 로고
    • The new nutrition Science project
    • Cannon G & Leitzmann C (2005) The new nutrition Science project. Public Health Nutr 8, 673-694.
    • (2005) Public Health Nutr , vol.8 , pp. 673-694
    • Cannon, G.1    Leitzmann, C.2
  • 64
    • 36249019203 scopus 로고    scopus 로고
    • Reductions in cardiovascular risk in association with population screening: A 10-year longitudinal study
    • McCluskey S, Baker D, Percy D, Lewis P & Middleton E (2007) Reductions in cardiovascular risk in association with population screening: a 10-year longitudinal study. J Public Health (Oxf) 29, 379-387.
    • (2007) J Public Health (Oxf) , vol.29 , pp. 379-387
    • McCluskey, S.1    Baker, D.2    Percy, D.3    Lewis, P.4    Middleton, E.5


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