Role of JNK in network formation of human lung microvascular endothelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 294, Issue 4, 2008, Pages

  Medhora, Meetha ^a   Dhanasekaran, Anuradha ^a   Pratt Jr , Phillip F ^a   Cook, Craig R ^a   Dunn, Laurel K ^a   Gruenloh, Stephanie K ^a   Jacobs, Elizabeth R ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Dominant negative mitogen activated protein kinase extracellular signal regulated kinase kinase; Extracellular signal regulated kinase; Mitogen activated protein kinase; Mitogen activated protein kinase phosphatase; PD 184352

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 (2 CHLORO 4 IODOANILINO) N CYCLOPROPYLMETHOXY 3,4 DIFLUOROBENZAMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; SYNAPTOPHYSIN;

ANGIOGENESIS; ARTICLE; CHORIOALLANTOIS; GENE OVEREXPRESSION; HUMAN LUNG MICROVASCULAR ENDOTHELIAL CELL; LUNG ENDOTHELIUM; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; COLLAGEN; DRUG COMBINATIONS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; FLAVONOIDS; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; LAMININ; MAP KINASE KINASE 4; MICROCIRCULATION; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEOGLYCANS; PULMONARY CIRCULATION;

EID: 42049122785     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00496.2007     Document Type: Article

References (44)

1. Bayless KJ, Salazar R, Davis GE. RGD-dependent vacuolation and lumen formation observed during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the alpha(v)beta(3) and alpha(5)beta(1) integrins. Am J Pathol 156: 1673-1683, 2000.
2. Bein K, Odell-Fiddler ET, Drinane M. Role of TGF-β1 and JNK signaling in capillary tube patterning. Am J Physiol Cell Physiol 287: C1012-C1022, 2004.
3. Bokemeyer D, Ostendorf T, Kunter U, Lindemann M, Kramer HJ, Floege J. Differential activation of mitogen-activated protein kinases in experimental mesangioproliferative glomerulonephritis. J Am Soc Nephrol 11: 232-240, 2000.
4. Boutros M, Paricio N, Strutt DI, Mlodzik M. Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell 94: 109-118, 1998.
5. Brondello JM, Pouyssegur J, McKenzie FR. Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation. Science 286: 2514-2517, 1999.
6. Camps M, Nichols A, Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J 14: 6-16, 2000.
7. Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 6: 389-395, 2000.
8. Chu Y, Solski PA, Khosravi-Far R, Der CJ, Kelly K. The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation. J Biol Chem 271: 6497-6501, 1996.
9. Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 103: 239-252, 2000.
10. Dixelius J, Jakobsson L, Genersch E, Bohman S, Ekblom P, Claesson-Welsh L. Laminin-1 promotes angiogenesis in synergy with fibroblast growth factor by distinct regulation of the gene and protein expression profile in endothelial cells. J Biol Chem 279: 23766-23772, 2004.
11. Doi M, Thyboll J, Kortesmaa J, Jansson K, Iivanainen A, Parvardeh M, Timpl R, Hedin U, Swedenborg J, Tryggvason K. Recombinant human laminin-10 (alpha5beta1gamma1). Production, purification, and migration-promoting activity on vascular endothelial cells. J Biol Chem 277: 12741-12748, 2002.
12. Dunn LK, Gruenloh SK, Dunn BE, Reddy DS, Falck JR, Jacobs ER, Medhora M. Chick chorioallantoic membrane as an in vivo model to study vasoreactivity: characterization of development-dependent hyperemia induced by epoxyeicosatrienoic acids (EETs). Anat Rec A Discov Mol Cell Evol Biol 285: 771-780, 2005.
13. English D, Brindley DN, Spiegel S, Garcia JG. Lipid mediators of angiogenesis and the signaling pathways they initiate. Biochim Biophys Acta 1582: 228-239, 2002.
14. Flint AJ, Tiganis T, Barford D, Tonks NK. Development of "substratetrapping" mutants to identify physiological substrates of protein tyrosine phosphatases. Proc Natl Acad Sci USA 94: 1680-1685, 1997.
15. Foschi M, Chari S, Dunn MJ, Sorokin A. Biphasic activation of p21ras by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase. EMBO J 16: 6439-6451, 1997.
16. Franklin CC, Kraft AS. Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells. J Biol Chem 272: 16917-16923, 1997.
17. Groom LA, Sneddon AA, Alessi DR, Dowd S, Keyse SM. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO J 15: 3621-3632, 1996.
18. Hangai M, Kitaya N, Xu J, Chan CK, Kim JJ, Werb Z, Ryan SJ, Brooks PC. Matrix metalloproteinase-9-dependent exposure of a cryptic migratory control site in collagen is required before retinal angiogenesis. Am J Pathol 161: 1429-1437, 2002.
19. Hirsch DD, Stork PJ. Mitogen-activated protein kinase phosphatases inactivate stress-activated protein kinase pathways in vivo. J Biol Chem 272: 4568-4575, 1997.
20. Ilan N, Mahooti S, Madri JA. Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis. J Cell Sci 111: 3621-3631, 1998.
21. Javaherian K, Park SY, Pickl WF, LaMontagne KR, Sjin RT, Gillies S, Lo KM. Laminin modulates morphogenic properties of the collagen XVIII endostatin domain. J Biol Chem 277: 45211-45218, 2002.
22. Kleinman HK, McGarvey ML, Liotta LA, Robey PG, Tryggvason K, Martin GR. Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma. Biochemistry 21: 6188-6193, 1982.
23. Laderoute KR, Mendonca HL, Calaoagan JM, Knapp AM, Giaccia AL, Stork PJ. Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity. J Biol Chem 274: 12890-12897, 1999.
24. Lasa M, Mahtani KR, Finch A, Brewer G, Saklatvala J, Clark AR. Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade. Mol Cell Biol 20: 4265-4274, 2000.
25. Lee OH, Kim YM, Lee YM, Moon EJ, Lee DJ, Kim JH, Kim KW, Kwon YG. Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells. Biochem Biophys Res Commun 264: 743-750, 1999.
26. Li S, Harrison D, Carbonetto S, Fassler R, Smyth N, Edgar D, Yurchenco PD. Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation. J Cell Biol 157: 1279-1290, 2002.
27. Liu F, Verin AD, Wang P, Day R, Wersto RP, Chrest FJ, English DK, Garcia JG. Differential regulation of sphingosine-1-phosphate- and VEGF-induced endothelial cell chemotaxis. Involvement of G(ialpha2)-linked Rho kinase activity. Am J Respir Cell Mol Biol 24: 711-719, 2001.
28. Matsumoto T, Turesson I, Book M, Gerwins P, Claesson-Welsh L. p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis. J Cell Biol 156: 149-160, 2002.
29. McEwen DG, Cox RT, Peifer M. The canonical Wg and JNK signaling cascades collaborate to promote both dorsal closure and ventral patterning. Development 127: 3607-3617, 2000.
30. Medhora M, Daniels J, Mundey K, Fisslthaler B, Busse R, Jacobs ER, Harder DR. Epoxygenase-driven angiogenesis in human lung microvascular endothelial cells. Am J Physiol Heart Circ Physiol 284: H215-H224, 2003.
31. Medhora M, Narayanan J, Harder D. Dual regulation of the cerebral microvasculature by epoxyeicosatrienoic acids. Trends Cardiovasc Med 11: 38-42, 2001.
32. Miner JH, Cunningham J, Sanes JR. Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain. J Cell Biol 143: 1713-1723, 1998.
33. Ono K, Han J. The p38 signal transduction pathway: activation and function. Cell Signal 12: 1-13, 2000.
34. Peters K, Troyer D, Kummer S, Kirkpatrick CJ, Rauterberg J. Apoptosis causes lumen formation during angiogenesis in vitro. Microvasc Res 64: 334-338, 2002.
35. Potente M, Michaelis UR, Fisslthaler B, Busse R, Fleming I. Cytochrome P450 2C9-induced endothelial cell proliferation involves induction of mitogen-activated protein (MAP) kinase phosphatase-1, inhibition of the c-Jun N-terminal kinase, and up-regulation of cyclin D1. J Biol Chem 277: 15671-15676, 2002.
36. Pratt PF, Bokemeyer D, Foschi M, Sorokin A, Dunn MJ. Alterations in subcellular localization of p38 MAPK potentiates endothelin-stimulated COX-2 expression in glomerular mesangial cells. J Biol Chem 278: 51928-51936, 2003.
37. Sottile J. Regulation of angiogenesis by extracellular matrix. Biochim Biophys Acta 1654: 13-22, 2004.
38. Stupack DG. Integrins as a distinct subtype of dependence receptors. Cell Death Differ 12: 1021-1030, 2005.
39. Stupack DG, Puente XS, Boutsaboualoy S, Storgard CM, Cheresh DA. Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins. J Cell Biol 155: 459-470, 2001.
40. Thyboll J, Kortesmaa J, Cao R, Soininen R, Wang L, Iivanainen A, Sorokin L, Risling M, Cao Y, Tryggvason K. Deletion of the laminin alpha4 chain leads to impaired microvessel maturation. Mol Cell Biol 22: 1194-1202, 2002.
41. Wallingford JB, Rowning BA, Vogeli KM, Rothbacher U, Fraser SE, Harland RM. Dishevelled controls cell polarity during Xenopus gastrulation. Nature 405: 81-85, 2000.
42. Xu J, Rodriguez D, Petitclerc E, Kim JJ, Hangai M, Moon YS, Davis GE, Brooks PC. Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo. J Cell Biol 154: 1069-1079, 2001.
43. Yancopoulos GD, Klagsbrun M, Folkman J. Vasculogenesis, angiogenesis, and growth factors: ephrins enter the fray at the border. Cell 93: 661-664, 1998.
44. Yang B, Cao DJ, Sainz I, Colman RW, Guo YL. Different roles of ERK and p38 MAP kinases during tube formation from endothelial cells cultured in 3-dimensional collagen matrices. J Cell Physiol 200: 360-369, 2004.