Different roles of ERK and p38 MAP kinases during tube formation from endothelial cells cultured in 3-dimensional collagen matrices

Journal of Cellular Physiology

Volumn 200, Issue 3, 2004, Pages 360-369

  Yang, Baohua ^a   Cao, Dian J ^a   Sainz, Irma ^a   Colman, Robert W ^a   Guo, Yan Lin ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CELL CYCLE PROTEIN; COLLAGEN GEL; CYCLIN DEPENDENT KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE; PROTEIN P27; RETINOBLASTOMA PROTEIN;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL ELONGATION; CELL PROLIFERATION; CELL STRUCTURE; CELL VACUOLE; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INHIBITION; HUMAN; HUMAN CELL; MORPHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CELL SURVIVAL; COLLAGEN TYPE I; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; EXTRACELLULAR MATRIX; FLAVONOIDS; GELS; GENE EXPRESSION REGULATION; HUMANS; IMIDAZOLES; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; UMBILICAL VEINS;

EID: 3442888779     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20025     Document Type: Article

References (44)

1. Becker PM, Verin AD, Booth MA, Liu F, Birukova A, Garcia JG. 2001. Differential regulation of diverse physiological responses to VEGF in pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol 281:L1500-L1511.
2. Beckner ME. 1999. Factors promoting tumor angiogenesis. Cancer Invest 17:594-623.
3. Budihardjo I, Oliver H, Lutter M, Luo X, Wang X. 1999. Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 15:269-290.
4. Cao Y, Chen A, An SSA, Ji RW, Davidson D, Llinas M. 1997. Kringle 5 of plasminogen is a novel inhibitor of endothelial cell growth. J Biol Chem 272:22924-22928.
5. Chavakis E, Dimmeler S. 2002. Regulation of endothelial cell survival and apoptosis during angiogenesis. Arterioscler Thromb Vasc Biol 22:887-893.
6. Cobb MH, Boulton TG, Robbins DJ. 1991. Extracellular signal-regulated kinases: ERKs in progress. Cell Regul 2:965-978.
7. Colman RW, Jameson BA, Lin Y, Johnson D, Mousa SA. 2000. Domain 5 of high molecular weight kininogen (kininostatin) down-regulates endothelial cell proliferation and migration and inhibits angiogenesis. Blood 95:543-550.
8. Davis GE, Camarillo CW. 1996. An alpha 2 beta 1 integrin-dependent pinocytic mechanism involving intracellular vacuole formation and coalescence regulates capillary lumen and tube formation in three-dimensional collagen matrix. Exp Cell Res 224:39-51.
9. Davis GE, Bayless KJ, Mavila A. 2002. Molecular basis of endothelial cell morphogenesis in three-dimensional extracellular matrices. Anat Rec 268:252-275.
10. Dudley DT, Pang L, Decker SJ, Bridges AJ, Saltiel AR. 1995. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 92:7686-7689.
11. Folkman J, Shing Y. 1992. Angiogenesis. J Biol Chem 267:10931-10934.
12. Griffloen AW, Molema G. 2000. Angiogenesis: Potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation. Pharmacol Rev 52:237-268.
13. Guay J, Lambert H, Gingras-Breton G, Lavoie JN, Huot J, Landry J. 1997. Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27. J Cell Sci 110:357-368.
14. Gum RJ, McLaughlin MM, Kumar S, Wang Z, Bower MJ, Lee JC, Adams JL, Livi GP, Goldsmith EJ, Young PR. 1998. Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket. J Biol Chem 273:15605-15610.
15. Guo YL, Kang B, Yang LJ, Williamson JR. 1999. Tumor necrosis factor-alpha and ceramide induce cell death through different mechanisms in rat mesangial cells. Am J Physiol 276:F390-F397.
16. Guo YL, Wang S, Colman RW. 2001a. Kininostatin, an angiogenic inhibitor, inhibits proliferation and induces apoptosis of human endothelial cells. Arterioscler Thromb Vasc Biol 21:1427-1433.
17. Guo YL, Kang B, Han J, Williamson JR. 2001b. p38beta MAP kinase protects rat mesangial cells from TNF-alpha-induced apoptosis. J Cell Biochem 82:556-565.
18. Guo YL, Wang S, Cao DJ, Colman RW. 2003. Apoptotic effect of cleaved high molecular weight kininogen is regulated by extracellular matrix proteins. J Cell Biochem 89:622-632.
19. Hale KK, Trollinger D, Rihanek M, Manthey CL. 1999. Differential expression and activation of p38 mitogen-activated protein kinase α, β, δ, and γ in inflammatory cell lineages. J Immunol 162:4246-4252.
20. Ilan N, Mahooti S, Madri JA. 1998. Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis. J Cell Sci 111:3621-3631.
21. Ingber DE. 2002. Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology. Circ Res 91:877-887.
22. Jiang Y, Gram H, Zhao M, New L, Gu J, Feng L, Di Padova F, Ulevitch RJ, Han J. 1997. Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta. J Biol Chem 272:30122-30128.
23. Kayyali US, Pennella CM, Trujillo C, Villa O, Gaestel M, Hassoun PM. 2002. Cytoskeletal changes in hypoxic pulmonary endothelial cells are dependent on MAPK-activated protein kinase MK2. J Biol Chem 277:42596.
24. King KL, Cidlowski JA. 1998 Cell cycle regulation and apoptosis. Annu Rev Physiol 60:601-617.
25. Krupinski J, Slevin M, Marti E, Catena E, Rubio F, Gaffney J. 2003. Time-course phosphorylation of the mitogen activated protein (MAP) kinase group of signalling proteins and related molecules following middle cerebral artery occlusion (MCAO) in rats. Neuropathol Appl Neurobiol 29:144-158.
26. Kyriakis JM, Avruch J. 1996. Sounding the alarm: Protein kinase cascades activated by stress and inflammation. J Biol Chem 271:24313-24316.
27. Lee J, Hong F, Kwon S, Kim SS, Kim DO, Kang HS, Lee SJ, Ha J, Kim SS. 2002. Activation of p38 MAPK induces cell cycle arrest via inhibition of Raf/ERK pathway during muscle differentiation. Biochem Biophys Res Commun 298:765-771.
28. Lew DJ, Kornbluth S. 1996. Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control. Curr Opin Cell Biol 8:795-804.
29. Matsumoto T, Turesson I, Book M, Gerwins P, Claesson-Welsh L. 2002. p38 MAP kinase negatively regulates endothelial cell survival, proliferation, and differentiation in FGF-2-stimulated angiogenesis. J Cell Biol 156:149-160.
30. Mudgett JS, Ding J, Guh-Siesel L, Chartrain NA, Yang L, Gopal S, Shen MM. 2000. Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis. Proc Natl Acad Sci USA 97:10454-10459.
31. Nemoto S, Xiang J, Huang S, Lin A. 1998. Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase. J Biol Chem 273:16415-16420.
32. O'Reilly MS, Boehm T, Shing Y, Fukai N, Vasios G, Lane WS, Flynn E, Birkhead JR, Olsen BR, Folkman J. 1997. Endostatin: An endogenous inhibitor of angiogenesis and tumor growth. Cell 88:277-285.
33. Ono K, Han J. 2000. The p38 signal transduction pathway: Activation and function. Cell Signal 12:1-13.
34. Page K, Li J, Hershenson MB. 2001. p38 MAP kinase negatively regulates cyclin D1 expression in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 280:L955-L964.
35. Peters K, Troyer D, Kummer S, Kirkpatrick CJ, Rauterberg J. 2002. Apoptosis causes lumen formation during angiogenesis in vitro. Microvasc Res 64:334-338.
36. Regan CP, Li W, Boucher DM, Spatz S, Su MS, Kuida K. 2002. Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects. Proc Natl Acad Sci USA 99:9248-9253.
37. Roovers K, Assoian RK. 2000. Integrating the MAP kinase signal into the G1 phase cell cycle machinery. Bioessays 22:818-826.
38. Sears RC, Nevins JR. 2002. Signaling networks that link cell proliferation and cell fate. J Biol Chem 277:11617.
39. Wang Y, Huang S, Sah VP, Ross J Jr, Brown JH, Han J, Chien KR. 1998. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J Biol Chem 273:2161-2168.
40. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. 1995. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270:1326-1331.
41. Yang S, Graham J, Kahn JW, Schwartz EA, Gerritsen ME. 1999. Functional roles for PECAM-1 (CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels. Am J Pathol 155:887-895.
42. Yu Y, Sato JD. 1999. MAP kinases, phosphatidylinositol 3-kinase, and p70 S6 kinase mediate the mitogenic response of human endothelial cells to vascular endothelial growth factor. J Cell Physiol 178:235-246.
43. Zhang JC, Claffey K, Sakthivel R, Darzynkiewicz Z, Shaw DE, Leal J, Wang YC, Lu FM, McCrae KR. 2000. Two-chain high molecular weight kininogen induces endothelial cell apoptosis and inhibits angiogenesis: Partial activity within domain 5. FASEB J 14:2589-2600.
44. Zhu WH, MacIntyre A, Nicosia RF. 2002. Regulation of angiogenesis by vascular endothelial growth factor and angiopoietin-1 in the rat aorta model: Distinct temporal patterns of intracellular signaling correlate with induction of angiogenic sprouting. Am J Pathol 161:823-830.