CD8α+βlow effector T cells in systemic lupus erythematosus

Scandinavian Journal of Immunology

Volumn 67, Issue 5, 2008, Pages 501-508

  Werwitzke, S ^a   Tiede, A ^a   Jacobs, R ^a   Zielinska Skowronek, M ^a   Buyny, S ^a   Schmidt, R E ^a   Witte, T ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD8ALPHA ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; CD3 ANTIGEN; CD8 ANTIGEN; CD8ALPHABETA ANTIGEN; CYTOKINE; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; ANTIGEN DETECTION; ARTICLE; AUTOIMMUNE DISEASE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; EFFECTOR CELL; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOSTIMULATION; PHENOTYPE; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL GRANULE; CYTOLOGY; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; PRE T LYMPHOCYTE; T LYMPHOCYTE;

ANTIGENS, CD3; ANTIGENS, CD8; CELL DIFFERENTIATION; CYTOKINES; CYTOPLASMIC GRANULES; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE COUNT; PRECURSOR CELLS, T-LYMPHOID; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES;

EID: 42049089210     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2008.02093.x     Document Type: Article

References (46)

1. Hahn BH. Antibodies to DNA. N Engl J Med 1998 338 : 1359 68.
2. Grootscholten C, van Bruggen MC, van der Pijl JW et al. Deposition of nucleosomal antigens (histones and DNA) in the epidermal basement membrane in human lupus nephritis. Arthritis Rheum 2003 48 : 1355 62.
3. Ehrenstein MR, Katz DR, Griffiths MH et al. Human IgG anti-DNA antibodies deposit in kidneys and induce proteinuria in SCID mice. Kidney Int 1995 48 : 705 11.
4. Clynes R, Dumitru C, Ravetch JV. Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. Science 1998 279 : 1052 4.
5. + cells to support autoantibody synthesis. Arthritis Rheum 1990 33 : 1216 25.
6. Ohtsuka K, Gray JD, Stimmler MM, Toro B, Horwitz DA. Decreased production of TGF-beta by lymphocytes from patients with systemic lupus erythematosus. J Immunol 1998 160 : 2539 45.
7. Busser BW, Adair BS, Erikson J, Laufer TM. Activation of diverse repertoires of autoreactive T cells enhances the loss of anti-dsDNA B cell tolerance. J Clin Invest 2003 112 : 1361 71.
8. + T suppressor cell function in patients with active systemic lupus erythematosus. J Immunol 2001 166 : 6452 7.
9. Jacobs R, Pawlak CR, Mikeska E et al. Systemic lupus erythematosus and rheumatoid arthritis patients differ from healthy controls in their cytokine pattern after stress exposure. Rheumatology (Oxford) 2001 40 : 868 75.
10. - (double negative) T cells in patients with systemic lupus erythematosus: production of IL-4. Lupus 2002 11 : 501 7.
11. Emlen W, Niebur J, Kadera R. Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J Immunol 1994 152 : 3685 92.
12. James JA, Neas BR, Moser KL et al. Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure. Arthritis Rheum 2001 44 : 1122 6.
13. Herrmann M, Voll RE, Zoller OM, Hagenhofer M, Ponner BB, Kalden JR. Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus. Arthritis Rheum 1998 41 : 1241 50.
14. Casciola-Rosen L, Andrade F, Ulanet D, Wong WB, Rosen A. Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity. J Exp Med 1999 190 : 815 26.
15. + T cells from HIV-infected persons. J Immunol 1994 153 : 412 20.
16. van Lier RA, ten Berge IJ, Gamadia LE. Human CD8(+) T-cell differentiation in response to viruses. Nat Rev Immunol 2003 3 : 931 9.
17. - T cells in untreated hemato-oncological patients are expanded and display a Th1-type cytokine secretion profile, ex vivo cytolytic activity and enhanced tendency to apoptosis. Leukemia 1998 12 : 1573 82.
18. Gao GF, Jakobsen BK. Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor. Immunol Today 2000 21 : 630 6.
19. Renard V, Romero P, Vivier E, Malissen B, Luescher IF. CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding. J Exp Med 1996 184 : 2439 44.
20. Norment AM, Littman DR. A second subunit of CD8 is expressed in human T cells. EMBO J 1988 7 : 3433 9.
21. Moebius U, Kober G, Griscelli AL, Hercend T, Meuer SC. Expression of different CD8 isoforms on distinct human lymphocyte subpopulations. Eur J Immunol 1991 21 : 1793 800.
22. Renard V, Delon J, Luescher IF, Malissen B, Vivier E, Trautmann A. The CD8 beta polypeptide is required for the recognition of an altered peptide ligand as an agonist. Eur J Immunol 1996 26 : 2999 3007.
23. Witte T, Spoerl R, Chang HC. The CD8beta ectodomain contributes to the augmented coreceptor function of CD8alphabeta heterodimers relative to CD8alphaalpha homodimers. Cell Immunol 1999 191 : 90 6.
24. + T cells in the thymus. Immunity 2000 12 : 409 18.
25. Irie HY, Ravichandran KS, Burakoff SJ. CD8 beta chain influences CD8 alpha chain-associated Lck kinase activity. J Exp Med 1995 181 : 1267 73.
26. Werwitzke S, Tiede A, Drescher BE, Schmidt RE, Witte T. CD8beta/CD28 expression defines functionally distinct populations of peripheral blood T lymphocytes. Clin Exp Immunol 2003 133 : 334 43.
27. Konno A, Okada K, Mizuno K et al. CD8alpha alpha memory effector T cells descend directly from clonally expanded CD8alpha +beta high TCRalpha beta T cells in vivo. Blood 2002 100 : 4090 7.
28. Schmitz JE, Forman MA, Lifton MA et al. Expression of the CD8alpha beta-heterodimer on CD8(+) T lymphocytes in peripheral blood lymphocytes of human immunodeficiency virus- and human immunodeficiency virus+ individuals. Blood 1998 92 : 198 206.
29. Tan EM, Cohen AS, Fries JF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982 25 : 1271 7.
30. Terry LA, DiSanto JP, Small TN, Flomenberg N. Differential expression and regulation of the human CD8 alpha and CD8 beta chains. Tissue Antigens 1990 35 : 82 91.
31. + T lymphocyte subsets that express HLA class I-specific inhibitory receptors represent oligoclonally or monoclonally expanded cell populations. Proc Natl Acad Sci U S A 1996 93 : 12433 8.
32. + T cells by inhibitory natural killer cell receptors. Microbes Infect 2003 5 : 169 77.
33. Jacobs R, Weber K, Wendt K, Heiken H, Schmidt RE. Altered coexpression of lectin-like receptors CD94 and CD161 on NK and T cells in HIV patients. J Clin Immunol 2004 24 : 281 6.
34. + T cells. Curr Opin Immunol 2001 13 : 465 70.
35. + T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus. Arthritis Rheum 2005 52 : 201 11.
36. Kang I, Quan T, Nolasco H et al. Defective control of latent Epstein-Barr virus infection in systemic lupus erythematosus. J Immunol 2004 172 : 1287 94.
37. Parks CG, Cooper GS, Hudson LL et al. Association of Epstein-Barr virus with systemic lupus erythematosus: effect modification by race, age, and cytotoxic T lymphocyte-associated antigen 4 genotype. Arthritis Rheum 2005 52 : 1148 59.
38. - cell population in the blood and lung of HIV-positive patients. J Acquir Immune Defic Syndr 1993 6 : 1194 204.
39. - T cells. Aids 1994 8 : 431 41.
40. Sfikakis PP, Zografou A, Viglis V et al. CD28 expression on T cell subsets in vivo and CD28-mediated T cell response in vitro in patients with rheumatoid arthritis. Arthritis Rheum 1995 38 : 649 54.
41. Ren Y, Tang J, Mok MY, Chan AW, Wu A, Lau CS. Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus. Arthritis Rheum 2003 48 : 2888 97.
42. Taylor PR, Carugati A, Fadok VA et al. A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo. J Exp Med 2000 192 : 359 66.
43. Seery JP, Carroll JM, Cattell V, Watt FM. Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis. J Exp Med 1997 186 : 1451 9.
44. Amital H, Levi Y, Blank M et al. Immunomodulation of murine experimental SLE-like disease by interferon-gamma. Lupus 1998 7 : 445 54.
45. Smolen JS, Steiner G, Aringer M. Anti-cytokine therapy in systemic lupus erythematosus. Lupus 2005 14 : 189 91.
46. Aringer M, Smolen JS. SLE - complex cytokine effects in a complex autoimmune disease: tumor necrosis factor in systemic lupus erythematosus. Arthritis Res Ther 2003 5 : 172 7.