CD57+/CD28- T cells in untreated hemato-oncological patients are expanded and display a Th1-type cytokine secretion profile, ex vivo cytolytic activity and enhanced tendency to apoptosis

Leukemia

Volumn 12, Issue 10, 1998, Pages 1573-1582

  Van Den Hove, L E ^a   Van Gool, S W ^a   Vandenberghe, P ^a   Boogaerts, Ma ^a   Ceuppens, J L ^a,b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

CD28; CD57; Cytokine secretion; Cytotoxic T lymphocytes; Neoplasia

Indexed keywords

CD28 ANTIGEN; CD57 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; MONOCLONAL ANTIBODY CD3; TUMOR NECROSIS FACTOR ALPHA;

ADULT; APOPTOSIS; ARTICLE; B CELL LEUKEMIA; CELL SEPARATION; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOLYSIS; FLOW CYTOMETRY; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; LYMPHOCYTE SUBPOPULATION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0031660446     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401146     Document Type: Article

References (9)

1. Chou DKH, Ilyas AA, Evans JE, Costello C, Quarles RH, Jungalwa FB. Structure of sulfated glucuronyl glycolipids in the nervous system reacting with HNK-1 antibody and some IgM paraproteins in neuropathy. J Biol Chem 1986; 261: 11717-11725.
2. Kubagawa H, Abo T, Balch CM, Cooper MS. Biochemical analysis of antigenic determinants recognized on human natural killer cells by HNK-1 (Leu-7) antibody. Fed Proc 1983; 42: 1219.
3. Kruse J, Mailhammer R, Wernecke H, Faissner A, Sommer I, Goridis C, Schachner M. Neural cell adhesion molecules and myelinassociated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1. Nature 1984; 311: 153-155.
4. Needham LK, Schnaar RL. The HNK-1 reactive sulfoglucuronyl glycolipids are ligands for L-selectin and P-selectin but not E-selectin. Proc Natl Acad Sci USA 1993; 90: 1359-1363.
5. Lanier LL, Loken MR. Human lymphocyte subpopulations identified by using three-color immunofluorescence and flow cytometry analysis: correlation of Leu-2, Leu-3, Leu-7, Leu-8 and Leu-11 cell surface antigen expression. J Immunol 1984; 132: 151-156.
6. Hannet I, Erkeller-Yuksel F, Lydyard P, Deneys V, DeBruyère M. Developmental and maturational changes in human blood lymphocyte subpopulations. Immunol Today 1992; 13: 215-218.
7. + cells in human cytomegalovirus and other viral infections. Scand J Infect Dis Suppl 1995; 99: 69-77.
8. Clement LT, Grossi CE, Gartland GL. Morphological and phenotypic features of a subpopulation of Leu-2+ cells that suppress B cell differentiation. J Immunol 1984; 133: 2461-2466.
9. + lymphocyte subsets in relation to cytomegalovirus carrier status and its correlate with pokeweed mitogen-induced B cell differentiation. Clin Exp Immunol 1989; 74: 245-251.