Differential roles of phosphatidylinositol 3-kinase/akt pathway in retinal ganglion cell survival in rats with or without acute ocular hypertension

Neuroscience

Volumn 153, Issue 1, 2008, Pages 214-225

  Huang, Y ^a,b   Cen, L P ^a   Luo, J M ^c   Wang, N ^b   Zhang, M Z ^c   van Rooijen, N ^d   Pang, C P ^a   Cui, Q ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c SHANTOU UNIVERSITY   (China)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

acute elevation of intraocular pressure; ischemic injury; macrophages; PI3K akt signal transduction pathway; retinal ganglion cells

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CLODRONIC ACID; FLUORESCENT DYE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; MACROPHAGE; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL SURVIVAL; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; MACROPHAGES; OCULAR HYPERTENSION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION; STILBAMIDINES;

EID: 41949089610     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.02.007     Document Type: Article

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