Retinal ganglion cell death after acute retinal ischemia is an ongoing process whose severity and duration depends on the duration of the insult

Neuroscience

Volumn 109, Issue 1, 2002, Pages 157-168

  Lafuente, M P ^a   Villegas Perez M P ^a   Selles Navarro I ^a   Mayor Torroglosa, S ^a   Miralles de Imperial, J ^a   Vidal Sanz, M ^a  

^a UNIVERSITY OF MURCIA   (Spain)

Author keywords

Adult rat retina; DiAsp; Ligature of the ophthalmic vessels; Neuronal degeneration; Retinal ganglion cell death; Transient ischemia

Indexed keywords

ASPARTIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL LABELING; CELL LOSS; CELL POPULATION; CELL SURVIVAL; CONTROLLED STUDY; DISEASE DURATION; DISEASE SEVERITY; LIGATION; NERVE DEGENERATION; NERVE TRANSECTION; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; RETINA ISCHEMIA;

ACUTE DISEASE; ANIMALS; BRAIN ISCHEMIA; CELL COUNT; CELL DEATH; CELL SURVIVAL; DISEASE PROGRESSION; FLUORESCENT DYES; NERVE DEGENERATION; PYRIDINIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RETINAL DISEASES; RETINAL GANGLION CELLS; STILBAMIDINES; TIME FACTORS;

EID: 0037126984     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(01)00458-4     Document Type: Article

References (65)

1. Mechanisms of the pathogenesis of glutamate neurotoxicity in retinal ischemia
2. Live or let die - Retinal ganglion cell death and survival during development and in the lesioned adult CNS
3. Prolonged bilateral carotid artery occlusion induces electrophysiological and immunohistochemical changes to the rat retina without causing histological damage
4. Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats
5. Cell death in the rat retina after a pressure-induced ischemia-reperfusion insult: An electron microsopic study: I: Ganglion cell layer and inner nuclear layer
6. Cell death in the rat retina after a pressure-induced ischemia-reperfusion insult: Electron microsopic study: II: Outer nuclear layer
7. Pressure-induced retinal ischemia in rats: An experimental model for quantitative study
8. Long-term preservation of intrinsic retinal neurons after axotomy-induced death of retinal ganaglion cells
9. Apoptosis and necrosis after reversible focal ischemia: An in situ DNA fragmentation analysis
10. Ischemia-induced neuronal apoptosis
11. Clinical trials with neuroprotective drugs in acute ischaemic stroke: Are we doing the right thing?
12. Effects of transient selective ligation of the ophthalmic vessels in the different layers of the adult rat retina
13. DNA strands breaks induced by sustained glutamate excitotoxicity in primary neuronal cultures
14. Pathobiology of ischaemic stroke: An integrated view
15. Monoclonal antibodies against carbohydrate differentiation antigens identify subsets of primary sensory neurones
16. Local hypothermia protects the retina from ischemia. A quantitative study in the rat
17. Apoptosis in adult rat retinal ganglion cells after axotomy
18. A paired comparison of two models of experimental retinal ischemia
19. Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro
20. Experimental occlusion of the central artery of the retina IV: Retinal tolerance time to acute ischemia
21. The blood vessels of the rat's eye
22. Necrosis and apoptosis after retinal ischemia: Involvement of NMDA-mediated excitotoxicity and p53
23. Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells
24. Neuronal death after brain injury. Models, mechanisms, and therapeutic strategies in vivo
25. Role of p38 mitogen-activated protein kinase in axotomy-induced apoptosis of rat retinal ganglion cells
26. Delayed neuronal death in the gerbil hippocampus following ischemia
27. Current concepts in neuroanatomical tracing
28. 2-selective adrenergic agonists against ischemia-induced retinal ganglion cell death
29. Apoptosis and caspases after ischemia-reperfusion injury in rat retina
30. Ischemic cell death in brain neurons
31. Intracellular calcium levels and calcium fluxes in the CA1 region of the rat hippocampal slice during in vitro ischemia: Relationship to electrophysiological damage
32. Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis
33. Microvasculature of the rat optic nerve head
34. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis
35. Influence of excitatory amino acids and ischemia on rat retinal choline acetyltransferase-containing cells
36. Expression of c-fos and c-jun mRNA following transient retinal ischemia: An approach using ligation of the retinal central artery in the rat
37. Effects of axotomy and intraocular administration of NT-4, NT-3, and BDNF on the survival of adult rat retinal ganglion cells: A quantitative in vito study
38. Postnatal changes in retinal ganglion cell and optic axon populations in the pigmented rat
39. Neuroprotection by the inhibition of apoptosis
40. Transient ischemia of the retina: Inner retinal layers neuroprotection with a selective alpha-2 agonist (AGN190342, Brominidine)
41. Retinal ischemia leads to apoptosis which is ameliorated by aurintricarboxylic acid
42. The role of the p53 protein in selective vulnerability of the inner retina to transient ischemia
43. Glutamate and the pathophysiology of hypoxia-ischemia brain damage
44. Neuronal apoptosis in acute necrotic insults: Why is this subject such a mess?
45. Intravenous brain-derived neurotrophic factor reduces infarct size and conterregulates Bax and Bcl-2 expression after temporaty focal cerebral ischemia
46. Retinal ganglion cell death after different transient periods of pressure-induced ischemia and survival intervals: A quantitative in vivo study
47. Apoptosis and necrosis in cerebrovascular disease
48. Activation of mitogen-activated protein kinases after transient forebrain ischemia in gerbil hippocampus
49. Optic nerve and peripapillary choroidal microvasculature of the rat eye
50. Ischemia and reperfusion-induced histologic changes in the rat retina
51. The relationship of microglial cells to dying neurons during natural neuronal cell death and axotomy-induced degeneration of the rat retina
52. Specific transcellular staining of microglia-supressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration 'in vivo' and 'in vitro'
53. Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat
54. Retinal ganglion cell death induced by retinal ischemia: Neuroprotective effects of two alpha-2 agonists
55. Long term effects of transient ischemia induced by selective ligature of the ophthalmic vessels on retinal ganglion cell survival
56. Death and neuroprotection of retinal ganglion cells after different types of injury
57. Persistent retrograde labelling of adult rat retinal ganglion cells with the carbocyanine dye diI
58. Effects of an alpha-2 agonist (AGN 190342, Brimonidine) on retinal ganglion cell survival after transient ischemia induced by selective ligature of the ophthalmic vessels
59. Transient ischemia of the retina: Long-term neuroprotection of inner retinal layers with a selective alpha-2 agonist (AGN190342, Brimonidine)
60. Influences of peripheral nerve grafts on the survival and regrowth of axotomized retinal ganglion cells in adult rats
61. Rapid and protracted phases of retinal ganglion cell loss follow axotomy in the optic nerve of adult rats
62. Neuronal death and survival in two models of hypoxic-ischemic brain damage
63. α2-Adrenoreceptor agonists are neuroprotective in a rat model of optic nerve degeneration
64. Co-existence of necrosis and apoptosis in rat hippocampus following transient forebrain ischemia
65. Neurobiology of disease