First CoMFA characterization of vesamicol analogs as ligands for the vesicular acetylcholine transporter

Journal of Medicinal Chemistry

Volumn 51, Issue 7, 2008, Pages 2128-2136

  Szymoszek, Andrzej ^a   Wenzel, Barbara ^b   Scheunemann, Matthias ^b   Steinbach, Jörg ^b   Schüürmann, Gerrit ^a,c  

^a HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c TU BERGAKADEMIE FREIBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 TERT BUTYLVESAMICOL; BENZOVESAMICOL; DECAHYDRONAPHTHALENEVESAMICOL; LIGAND; SPIROVESAMICOL; TROPANVESAMICOL; TROZAMICOL; UNCLASSIFIED DRUG; VESAMICOL DERIVATIVE; VESICULAR ACETYLCHOLINE TRANSPORTER;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE STUDY; EXPERIMENTAL STUDY; FIELD STUDY; MODEL; PREDICTION; QUANTITATIVE ANALYSIS; STATISTICS; TRAINING; VALIDATION STUDY;

BINDING SITES; ELECTROSTATICS; FLUOROBENZENES; IODOBENZENES; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PIPERIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REPRODUCIBILITY OF RESULTS; STEREOISOMERISM; VESICULAR ACETYLCHOLINE TRANSPORT PROTEINS;

EID: 41849140819     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm700961r     Document Type: Article

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