Characterization of the GNAQ promoter and association of increased Gq expression with cardiac hypertrophy in humans

European Heart Journal

Volumn 29, Issue 7, 2008, Pages 888-897

  Frey, Ulrich H ^a   Lieb, Wolfgang ^b   Erdmann, Jeanette ^b   Savidou, Danai ^a   Heusch, Gerd ^a   Leineweber, Kirsten ^a   Jakob, Heinz ^a   Hense, Hans Werner ^c   Löwel, Hannelore ^d   Brockmeyer, Norbert H ^e   Schunkert, Heribert ^b   Siffert, Winfried ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c UNIVERSITY OF MÜNSTER   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

G proteins; Hypertrophy; Polymorphism

Indexed keywords

GQ PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE; GENE AMPLIFICATION; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; GNAQ GENE; HEART FAILURE; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE; TRANSGENIC MOUSE;

ADULT; ANIMALS; CARDIOMEGALY; CELLS, CULTURED; FEMALE; GENE FREQUENCY; GENES, REPORTER; GENOTYPE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEINS; HEART FAILURE; HUMANS; MALE; MICE; MICE, TRANSGENIC; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); TRANSCRIPTION, GENETIC;

EID: 41849093329     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehm618     Document Type: Article

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