Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 10, 2008, Pages 3915-3920

  Wang, Jinyan ^a   Takeuchi, Hideyuki ^a   Sonobe, Yoshifumi ^a   Jin, Shijie ^a   Mizuno, Tetsuya ^a   Miyakawa, Shin ^b   Fujiwara, Masatoshi ^b   Nakamura, Yoshikazu ^c,d   Kato, Takuma ^e   Muramatsu, Hisako ^f   Muramatsu, Takashi ^f,g   Suzumura, Akio ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b RIBOMIC Inc   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g AICHI GAKUIN UNIVERSITY   (Japan)

Author keywords

Aptamer; Multiple sclerosis

Indexed keywords

APTAMER; CD4 ANTIGEN; FIBROBLAST GROWTH FACTOR; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MIDKINE; RNA; STAT5 PROTEIN; TRANSCRIPTION FACTOR FOXP3; CYTOKINE; FORKHEAD TRANSCRIPTION FACTOR; MYELIN ASSOCIATED GLYCOPROTEIN; OLIGODENDROCYTE MYELIN GLYCOPROTEIN; OLIGODENDROCYTE-MYELIN GLYCOPROTEIN; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CARCINOGENESIS; CD4+ CD25+ T LYMPHOCYTE; CELL POPULATION; CONTROLLED STUDY; EX VIVO STUDY; IMMUNOLOGICAL TOLERANCE; INFLAMMATION; LYMPH NODE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; SYMPTOMATOLOGY; TH1 CELL; TH17 CELL; TISSUE REPAIR; ANIMAL; C57BL MOUSE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; HELPER CELL; IMMUNOLOGY; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD4; APTAMERS, NUCLEOTIDE; CELL PROLIFERATION; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPH NODES; MICE; MICE, INBRED C57BL; MYELIN-ASSOCIATED GLYCOPROTEIN; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY;

EID: 41649100722     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0709592105     Document Type: Article

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