Interferon-γ induces microglial-activation-induced cell death: A hypothetical mechanism of relapse and remission in multiple sclerosis

Neurobiology of Disease

Volumn 22, Issue 1, 2006, Pages 33-39

  Takeuchi, Hideyuki ^a   Wang, Jinyan ^a   Kawanokuchi, Jun ^a   Mitsuma, Norimasa ^a   Mizuno, Tetsuya ^a   Suzumura, Akio ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Activation induced cell death; Apoptosis; Bax; Interferon ; Microglia; Multiple sclerosis

Indexed keywords

CASPASE INHIBITOR; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; PROTEIN BAX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL DEATH; CONTROLLED STUDY; IMMUNOBLOTTING; MICROGLIA; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; RELAPSE; REMISSION; SPINAL CORD; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; COCULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEEDBACK, BIOCHEMICAL; GLIOSIS; IN SITU NICK-END LABELING; INTERFERON TYPE II; MICE; MICE, INBRED C57BL; MICROGLIA; MODELS, NEUROLOGICAL; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; SPINAL CORD; UP-REGULATION;

EID: 33645081959     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.09.014     Document Type: Article

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