Vitamin E succinate induces ceramide-mediated apoptosis in head and neck squamous cell carcinoma in vitro and in vivo

Clinical Cancer Research

Volumn 14, Issue 6, 2008, Pages 1840-1848

  Gu, Xinbin ^a,b   Song, Xiaodong ^c,d   Dong, Yongheng ^e   Cai, Hui ^a   Walters, Eric ^a   Zhang, Renshu ^a,b   Pang, Xiaowu ^a   Xie, Tianpei ^c   Guo, Yinhan ^e   Sridhar, Rajagopalan ^a,b   Califano, Joseph A ^f  

^a HOWARD UNIVERSITY   (United States)

^b HOWARD UNIVERSITY CANCER CENTER   (United States)

^c Shanghai TenGen Biomedical Co Ltd   (China)

^d BINZHOU MEDICAL UNIVERSITY   (China)

^e Oriental TenGen Tech Development Co Ltd   (China)

^f JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; CASPASE 3; CASPASE 9; CERAMIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MDM2; PROTEIN P53; SPHINGOMYELIN PHOSPHODIESTERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; HEAD AND NECK CANCER; LIPID METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CASPASE 3; CASPASE 9; CELL PROLIFERATION; CELL SURVIVAL; CERAMIDES; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MICE; MICE, NUDE; POLY(ADP-RIBOSE) POLYMERASES; TUMOR CELLS, CULTURED; VITAMIN E; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 41549130926     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-07-1811     Document Type: Article

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