Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding

Structure

Volumn 16, Issue 4, 2008, Pages 558-569

  Lambert, Abigail R ^a,b   Sussman, Django ^b   Shen, Betty ^b   Maunus, Robert ^c   Nix, Jay ^d   Samuelson, James ^c   Xu, Shuang Yong ^c   Stoddard, Barry L ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c NEW ENGLAND BIOLABS   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

DNA

Indexed keywords

GENOMIC DNA; IRON; RESTRICTION ENDONUCLEASE; RESTRICTION ENDONUCLEASE NOTI; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; CRYSTAL STRUCTURE; DNA BINDING; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HYDROGEN BOND; IRON BINDING CAPACITY; MOLECULAR EVOLUTION; MOLECULAR RECOGNITION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN MOTIF; RESTRICTION MAPPING; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA; IRON; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 41449117713     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2008.01.017     Document Type: Article

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