Rational design of a chimeric endonuclease targeted to NotI recognition site

Protein Engineering, Design and Selection

Volumn 20, Issue 10, 2007, Pages 497-504

  Zhang, Penghua ^a   Bao, Yongming ^a   Higgins, Lauren ^a   Xu, Shuang Yong ^a  

^a NEW ENGLAND BIOLABS   (United States)

Author keywords

BcgI like enzyme; BmrI; Cleavage deficient mutant; Engineered endonuclease; NotI

Indexed keywords

CHIMERIC ENDONUCLEASE; DNA MANIPULATION; ENGINEERED ENDONUCLEASE;

BINDING SITES; DNA; MUTAGENESIS; POSITIVE IONS;

ENZYME ACTIVITY;

BINDING PROTEIN; EDETIC ACID; ENDONUCLEASE; PLASMID DNA; PROTEIN BMRI; PROTEIN EAGI; PROTEIN NOTI; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CHIMERA; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEOMICS;

BASE SEQUENCE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA CLEAVAGE; DRUG DESIGN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MOLECULAR SEQUENCE DATA; MUTANT CHIMERIC PROTEINS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; SUBSTRATE SPECIFICITY; TEMPERATURE;

EID: 36248983896     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzm049     Document Type: Article

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