The structure of Desulfovibrio vulgaris rubrerythrin reveals a unique combination of rubredoxin-like FeS4 and ferritin-like diiron domains

Nature Structural Biology

Volumn 3, Issue 6, 1996, Pages 539-546

  DeMaré, Fredrick ^a   Kurtz Jr , Donald M ^b   Nordlund, Pär ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN;

ARTICLE; DESULFOVIBRIO; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; CERULOPLASMIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME B GROUP; DESULFOVIBRIO VULGARIS; FERREDOXINS; FERRITINS; IRON; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; RUBREDOXINS;

BACTERIA (MICROORGANISMS); DESULFOVIBRIO; DESULFOVIBRIO VULGARIS;

EID: 0029949340     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb0696-539     Document Type: Article

References (21)

1. Moura, I., Tavares, P. & Ravi, N. Characterization of 3 proteins containing multiple iron sites - Rubrerythrin, desulforedoxin, and a protein containing a six-iron cluster. Meth. Enz. 243, 216-240 (1994).
2. 4 and Fe-O-Fe sites in rubrerythrin from Desulfovibrio vulgaris. Biochemistry 33, 3572-3576 (1994).
3. 57Fe-reconstituted rubrerythrin, a non-heme iron protein with structural analogies to ribonucleotide reductase. Biochemistry 32, 8487-8491 (1993).
4. Pierik, A.J., Wolbert, R.B.G., Portier, G.L., Verhagen, M.F.J.M. & Hagen, W.R. Nigerythrin and rubrerythrin from Desulfovibrio vulgaris each contain 2 mononuclear iron centers and 2 dinuclear iron clusters. European Journal of Biochemistry 212, 237-245 (1993).
5. Gupta, N. et al. Recombinant Desulfovibrio vulgaris rubrerythrin. Isolation and characterization of the diiron domain. Biochemistry 34, 3310-3318 (1995).
6. Prickril, B.C., Kurtz, D.M., Jr., LeGall, J. & Voordouw, G. Cloning and sequencing of the gene for Rubrerythrin from Desulfovibrio vulgaris (Hildenborough). Biochemistry 30, 11118-11123 (1991).
7. Kurtz, D.M., Jr. & Prickril, B.C. Intrapeptide sequence homology in rubrerythrin from Desulfovibrio vulgaris: Identification of potential ligands to the diiron site. Biochemical and Biophysical Research Communications 181, 337-341 (1991).
8. Nordlund, P. & Eklund, H. Di-iron-carboxylate proteins. Current Opinion in Structural Biology 5, 758-766 (1995).
9. Rosenzweig, A.C., Frederick, C.A., Lippard, S.J. & Nordlund, P. Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane. Nature 366, 537-543 (1993).
10. Rosenzweig, A.C., Nordlund, P., Takahara, P.M., Frederick, C.A. & Lippard, S.J. Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states. Chemistry & Biology 2, 409-418 (1995).
11. Nordlund, P., Sjöberg, B.-M. & Eklund, H. Three dimensional structure of the free radical protein of ribonucleotide reductase. Nature 345, 593-598 (1990).
12. Nordlund, P. & Eklund, H. Structure and function of the Escherichia coli ribonucleotide reductase protein R2. J. Mol. Biol. 231, 123-164 (1993).
13. Widell, L.C. & Hansen, T.A. The dissimilatory sulphate-reducing and sulfur-reducing bacteria, in The Prokaryotes (eds. A. Balows, H.G. Dworkin, W. Harder, & K.H. Schleifer) 583-624 (Springer-Verlag, New York, 1992).
14. Liu, M.Y. & LeGall, J. Purification and characterization of two proteins with inorganic pyrophosphatase activity from Desulfovibrio vulgaris: Rubrerythrin and a new, highly active, enzyme, Biochem. Biophys. Res. Commun. 171, 316-318 (1990).
15. Feig, A.L. & Lippard, S.J. Reactions of non-heme iron (II)centers with dioxygen in biology and chemistry. Chemical Reviews 94, 759-805 (1994).
16. Kurtz, D.M., Jr. Iron: Proteins with dinuclear active sites in Encyclopedia of Inorganic Chemistry (ed. King, R.B.) 1847-1859 (Wiley, Chichester, UK, 1994).
17. Stenkamp, R.E. Dioxygen and hemerythrin. Chemical Reviews 94, 715-726 (1994).
18. Fox, B.G., Shanklin, J., Ai, J., Loehr, T.M. & Sanders-Loehr, J. Resonance Raman evidence for anFe-O-Fe center in stearoyl-ACP destaurase. Primary sequence identity with other diiron-oxo proteins. Biochemistry 33, 12776-12786 (1994).
19. Harrison, P. & Lilley, T.H. Ferritin in Iron Carriers and Iron Proteins (ed.&(eds. Loehr, T.M.) 123-237 (VCH Publishers, New York, 1989).
20. Hempstead, P.D. et al. Direct observation of the iron binding sites in a ferritin. FEBS Letters 350, 258-262 (1994).
21. Frolow, F., Kalb(Gilboa), J. & Yariv, J. Structure of a unique two-fold symmetric haem-binding site. Nature Struct. Biology 1, 453-460 (1994).